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Fatma Dedeoglu, MD

Dedeoglu MD
Medicine Research
Immunology Research
Hospital Title:
Academic Title:
Assistant Professor of Pediatrics, Harvard Medical School
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  1. Henderson LA, Volpi S, Frugoni F, Janssen E, Kim S, Sundel RP, Dedeoglu F, Lo MS, Hazen MM, Beth Son M, Mathieu R, Zurakowski D, Yu N, Lebedeva T, Fuhlbrigge RC, Walter JE, Nee Lee Y, Nigrovic PA, Notarangelo LD. Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2016 Jul; 68(7):1758-68.
  2. Levy S, Dedeoglu F, Gaffin JM, Garvey KC, Harstad E, MacGinnitie A, Rufo PA, Huang Q, Ziemnik RE, Wisk LE, Weitzman ER. A Screening Tool for Assessing Alcohol Use Risk among Medically Vulnerable Youth. PLoS One. 2016; 11(5):e0156240.
  3. Freeman S, Bhatt A, Pedamallu C, King S, Duke F, Jung J, Lawton M, Anderson E, Fuhlbrigge RC, Kenna M, Licameli G, Meyerson M, Dedeoglu F. A121: in search of infectious triggers of periodic Fever, aphthous stomatitis, pharyngitis and adenitis syndrome. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S158.
  4. Henderson LA, Volpi S, Frugoni F, Kim S, Janssen E, Sundel RP, Dedeoglu F, Lo MS, Hazen MM, Mathieu R, Fuhlbrigge RC, Lee YN, Nigrovic PA, Notarangelo LD. A119: deep sequencing analysis of the T regulatory and T effector repertoire in juvenile idiopathic arthritis. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S156.
  5. Biggs C, Dedeoglu F. A81: spectrum of mevalonate kinase deficiency: is colitis more common than we think? Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S114.
  6. Hausmann JS, Dedeoglu F. Autoinflammatory diseases in pediatrics. Dermatol Clin. 2013 Jul; 31(3):481-94.
  7. Kentsis A, Shulman A, Ahmed S, Brennan E, Monuteaux MC, Lee YH, Lipsett S, Paulo JA, Dedeoglu F, Fuhlbrigge R, Bachur R, Bradwin G, Arditi M, Sundel RP, Newburger JW, Steen H, Kim S. Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease. EMBO Mol Med. 2013 Feb; 5(2):210-20.
  8. Borzutzky A, Stern S, Reiff A, Zurakowski D, Steinberg EA, Dedeoglu F, Sundel RP. Pediatric chronic nonbacterial osteomyelitis. Pediatrics. 2012 Nov; 130(5):e1190-7.
  9. Licameli G, Lawton M, Kenna M, Dedeoglu F. Long-term surgical outcomes of adenotonsillectomy for PFAPA syndrome. Arch Otolaryngol Head Neck Surg. 2012 Oct; 138(10):902-6.
  10. Ercan A, Barnes MG, Hazen M, Tory H, Henderson L, Dedeoglu F, Fuhlbrigge RC, Grom A, Holm IA, Kellogg M, Kim S, Adamczyk B, Rudd PM, Son MB, Sundel RP, Foell D, Glass DN, Thompson SD, Nigrovic PA. Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation. Arthritis Rheum. 2012 Sep; 64(9):3025-33.
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  12. Li SC, Torok KS, Pope E, Dedeoglu F, Hong S, Jacobe HT, Rabinovich CE, Laxer RM, Higgins GC, Ferguson PJ, Lasky A, Baszis K, Becker M, Campillo S, Cartwright V, Cidon M, Inman CJ, Jerath R, O'Neil KM, Vora S, Zeft A, Wallace CA, Ilowite NT, Fuhlbrigge RC. Development of consensus treatment plans for juvenile localized scleroderma: a roadmap toward comparative effectiveness studies in juvenile localized scleroderma. Arthritis Care Res (Hoboken). 2012 Aug; 64(8):1175-85.
  13. Samkari A, Borzutzky A, Fermo E, Treaba DO, Dedeoglu F, Altura RA. A novel missense mutation in MVK associated with MK deficiency and dyserythropoietic anemia. Pediatrics. 2010 Apr; 125(4):e964-8.
  14. Dedeoglu F. Drug-induced autoimmunity. Curr Opin Rheumatol. 2009 Sep; 21(5):547-51.
  15. Kim S, El-Hallak M, Dedeoglu F, Zurakowski D, Fuhlbrigge RC, Sundel RP. Complete and sustained remission of juvenile dermatomyositis resulting from aggressive treatment. Arthritis Rheum. 2009 Jun; 60(6):1825-30.
  16. Borzutzky A, Fried A, Chou J, Bonilla FA, Kim S, Dedeoglu F. NOD2-associated diseases: Bridging innate immunity and autoinflammation. Clin Immunol. 2010 Mar; 134(3):251-61.
  17. El-Hallak M, Giani T, Yeniay BS, Jacobs KE, Kim S, Sundel RP, Dedeoglu F. Chronic minocycline-induced autoimmunity in children. J Pediatr. 2008 Sep; 153(3):314-9.
  18. Jabara HH, Chaudhuri J, Dutt S, Dedeoglu F, Weng Y, Murphy MM, Franco S, Alt FW, Manis J, Geha RS. B-cell receptor cross-linking delays activation-induced cytidine deaminase induction and inhibits class-switch recombination to IgE. J Allergy Clin Immunol. 2008 Jan; 121(1):191-196.e2.
  19. Dedeoglu F, Sundel RP. Vasculitis in children. Rheum Dis Clin North Am. 2007 Aug; 33(3):555-83.
  20. Kim S, Dedeoglu F. Update on pediatric vasculitis. Curr Opin Pediatr. 2005 Dec; 17(6):695-702.
  21. Binstadt BA, Levine JC, Nigrovic PA, Gauvreau K, Dedeoglu F, Fuhlbrigge RC, Weindling SN, Newburger JW, Sundel RP. Coronary artery dilation among patients presenting with systemic-onset juvenile idiopathic arthritis. Pediatrics. 2005 Jul; 116(1):e89-93.
  22. Dedeoglu F, Sundel RP. Vasculitis in children. Pediatr Clin North Am. 2005 Apr; 52(2):547-75, vii.
  23. Castigli E, Wilson SA, Scott S, Dedeoglu F, Xu S, Lam KP, Bram RJ, Jabara H, Geha RS. TACI and BAFF-R mediate isotype switching in B cells. J Exp Med. 2005 Jan 3; 201(1):35-9.
  24. Dedeoglu F, Horwitz B, Chaudhuri J, Alt FW, Geha RS. Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB. Int Immunol. 2004 Mar; 16(3):395-404.
  25. Castigli E, Scott S, Dedeoglu F, Bryce P, Jabara H, Bhan AK, Mizoguchi E, Geha RS. Impaired IgA class switching in APRIL-deficient mice. Proc Natl Acad Sci U S A. 2004 Mar 16; 101(11):3903-8.
  26. Dedeoglu, F. and Sundel, R.P. Emergency Department management of Lyme disease. Clinical Pediatric Emergency Medicine. 2004; 5(1):54-62.
  27. Blaeser F, Bryce PJ, Ho N, Raman V, Dedeoglu F, Donaldson DD, Geha RS, Oettgen HC, Chatila TA. Targeted inactivation of the IL-4 receptor alpha chain I4R motif promotes allergic airway inflammation. J Exp Med. 2003 Oct 20; 198(8):1189-200.
  28. Jabara H, Laouini D, Tsitsikov E, Mizoguchi E, Bhan A, Castigli E, Dedeoglu F, Pivniouk V, Brodeur S, Geha R. The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching. Immunity. 2002 Sep; 17(3):265-76.
  29. Dedeoglu F, Rose CD, Athreya BH, Conard K, Grissom L, Magnusson M. Successful treatment of retroperitoneal fibrosis with tamoxifen in a child. J Rheumatol. 2001 Jul; 28(7):1693-5.
  30. Sundel, R.P., Dedeoglu, F. “ Periodic Fever Disorders.”. International Seminars in Pediatric Gastroenterology and Nutrition. 2000; 9(3):9-15.
  31. Kaymaz H, Dedeoglu F, Schluter SF, Edmundson AB, Marchalonis JJ. Cross-reactions of anti-immunoglobulin sera with synthetic T-cell receptor beta peptides: mapping on a 3-dimension model. Adv Exp Med Biol. 1994; 347:93-8.
  32. Dedeoglu F, Kaymaz H, Klein G, Marchalonis JJ. Light and heavy chains specifying a human IgM kappa autoantibody to a T-cell receptor V beta-antigen. Immunol Lett. 1993 Nov; 38(3):223-7.
  33. Kaymaz H, Dedeoglu F, Schluter SF, Edmundson AB, Marchalonis JJ. Reactions of anti-immunoglobulin sera with synthetic T cell receptor peptides: implications for the three-dimensional structure and function of the TCR beta chain. Int Immunol. 1993 May; 5(5):491-502.
  34. Dedeoglu F, Kaymaz H, Seaver N, Schluter SF, Yocum DE, Marchalonis JJ. Lack of preferential V beta usage in synovial T cells of rheumatoid arthritis patients. Immunol Res. 1993; 12(1):12-20.
  35. Marchalonis JJ, Kaymaz H, Dedeoglu F, Schluter SF, Yocum DE, Edmundson AB. Human autoantibodies reactive with synthetic autoantigens from T-cell receptor beta chain. Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8):3325-9.
  36. Marchalonis JJ, Dedeoglu F, Kaymaz H, Schluter SF, Edmundson AB. Antigenic mapping of a human lambda light chain: correlation with three dimensional structure. J Protein Chem. 1992 Apr; 11(2):129-37.
  37. Dedeoglu F, Hubbard RA, Schluter SF, Marchalonis JJ. T-cell receptors of man and mouse studied with antibodies against synthetic peptides. Exp Clin Immunogenet. 1992; 9(2):95-108.
  38. Marchalonis JJ, Dedeoglu F, Hohman VS, McGee K, Schluter SF, Edmundson AB. Antigenic mapping of light chains and T cell receptor beta chains. Adv Exp Med Biol. 1991; 303:235-42.
  39. Kaymaz, H.; Dedeoglu, F.; Schluter, S.F; Edmundson, A.B.; Marchalonis, J.J. . "Cross-reactions of anti immunoglobulin sera with T cell receptor-beta peptides: mapping on a 3- dimensional model. Proceedings of the Seventh International Symposium on Immunobiology of Proteins and Peptides. 1991.
  40. Marchalonis, J.J.; Dedeoglu, F.; Hohman, V.S.; Schluter, S.F; Edmundson, A.B. . "Antigenic mapping of light chains and Tcell receptor b chain". Proceedings of the Sixth International Symposium on Immunobiology of Proteins and Peptides. 1991; 235-242.
  41. Dedeoglu, F.; Ozcan, E,; Ang, O. "Corynebacterium Group D2 infection: A case report". Turkish J. of Infection. 1989; 3(4):450-463.
  42. Dedeoglu, F.; Oner, A.; Ang, O. "Cases of urinary tract infections caused by Salmonella thyphymurium". Turkish J. of Infection. 1989; 3(2):201-208.
  43. Dedeoglu, F.; Tunc, M.; Oner, A.; Onat, N.; Ang, O. "Urinary tract infection caused by Corynebacterium jeikeium ( Corynebacterium Group JK) " . Turkish J. of Infection. 1989; 3(4):465-472.
  44. Keskin, A.N.; Karaosmanoglu, P.; Ang, O.; Dedeoglu, F.; Muderrisoglu, C.; Gonenc, U. Leptospirosis: A case report". Turkish J. of Infection. 1989; 3(3):373-380.
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