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Dario  Fauza, MD, PhD

Dario Fauza
Department:
Surgery Research
Hospital Title:
Associate in Surgery
Academic Title:
Associate Professor of Surgery, Harvard Medical School
Research Focus Area:
Fetal Tissue Engineering
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Research Overview

Dario Fauza's research is directed at developing original, more effective ways to repair birth defects, both pre and postnatally. To that end, he has pioneered and explored a variety of approaches. One is fetal tissue engineering, or the use of fetal cells to produce tissue to repair congenital anomalies. This concept involves the minimally invasive harvest of fetal cells, which are then employed to engineer tissue in the laboratory while pregnancy is allowed to continue, so that a newborn, or a fetus with a prenatally diagnosed birth defect can benefit from having autologous, expanded tissue readily available for surgical reconstruction, either before or after birth. Fetal cells can be obtained from the fetus itself, the amniotic fluid, the placenta, or umbilical cord blood. This concept has already been applied successfully, in large animal models, for the creation of various types of fetal tissue used in the treatment of several anomalies, including congenital diaphragmatic hernia, tracheal and chest wall defects, bladder extrophy, and cardiac anomalies. Related projects for the treatment of other birth defects are also ongoing. The first human application of this new therapeutic concept is expected before long, as regulatory hurdles are currently being addressed. Another project is aimed at studying the immunological characteristics of fetal cells. Early results point to the fact that some of these cells are immunologically privileged, thus bettering their chances of engraftment after transplantation among different individuals. This may have many implications both in fetal tissue engineering and other fetal cell therapy applications.

Yet another area of interest to Dr. Fauza is the treatment of spina bifida. He has demonstrated that neural stem cells can partially repair damaged areas of the spinal cord in a large animal model of spina bifida, which could lead to improved outcomes in the treatment of this devastating disease. He is now perfecting the methods for isolation of neural stem cells and their delivery to the fetus or newborn, before human trials can be pursued.

He is also developing a novel method to facilitate clinical application of fetal tracheal occlusion as a means to treat lung hypoplasia (i.e. underdevelopment) associated with congenital diaphragmatic hernia. He has shown that fetal tracheal occlusion can be enhanced by intrapulmonary delivery of concentrated albumin, a protein that naturally occurs in the fetal lung liquid. The increased oncotic pressure in the fetal airway resulting from this intervention leads to an active expansion of fetal lung liquid. This, in turn, allows for fetal tracheal occlusion to become effective in the short term, late in gestation, thus avoiding prematurity, ever so prevalent with the current therapeutic methodology. This should lead to improved outcomes in this form of fetal treatment.

Finally, Dr. Fauza seeks to improve the safety of fetal surgery in general by studying fetal physiology during this form of intervention and by creating novel methods to prevent postoperative premature delivery. He has shown, experimentally, that direct local drug delivery to the uterus, rather than drug administration through the mother's blood stream, is a highly effective approach to control this dreadful and universal complication of fetal surgery. Among the drugs being tested for local administration to the uterus, Botox, which is known to inhibit muscular contractions, is among the most promising.

About Dario Fauza

Dario Fauza received an MD from the University of Sao Paulo Medical School, Brazil, where he also received a PhD-equivalent degree and completed an internship and residencies on both general and pediatric surgery at its Hospital of Clinics. He then moved to the United States, where he completed different clinical and research fellowships, as well as postdoctoral training, at Boston Children's Hospital.

He is the recipient of a number of research and funding grant awards, both in his native country and in the US, as well as of a Fellowship ad eundem (i.e. by invitation) by the Royal College of Surgeons of England the first surgeon from his home country to receive such an honor. He has an extensive bibliography and has been awarded different patents for the development of novel surgical devices.

Publications

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  1. Fauza DO. Tissue engineering in congenital diaphragmatic hernia. Semin Pediatr Surg. 2014 Jun; 23(3):135-40.
  2. Turner CG, Klein JD, Wang J, Thakor D, Benedict D, Ahmed A, Teng YD, Fauza DO. The amniotic fluid as a source of neural stem cells in the setting of experimental neural tube defects. Stem Cells Dev. 2013 Feb 15; 22(4):548-53.
  3. Gray FL, Turner CG, Ahmed A, Calvert CE, Zurakowski D, Fauza DO. Prenatal tracheal reconstruction with a hybrid amniotic mesenchymal stem cells-engineered construct derived from decellularized airway. J Pediatr Surg. 2012 Jun; 47(6):1072-9.
  4. Turner CG, Klein JD, Gray FL, Ahmed A, Zurakowski D, Fauza DO. Craniofacial repair with fetal bone grafts engineered from amniotic mesenchymal stem cells. J Surg Res. 2012 Dec; 178(2):785-90.
  5. Klein JD, Fauza DO. Amniotic and placental mesenchymal stem cell isolation and culture. Methods Mol Biol. 2011; 698:75-88.
  6. Nicksa GA, Yu DC, Kalish BT, Klein JD, Turner CG, Zurakowski D, Barnewolt CE, Fauza DO, Buchmiller TL. Serial amnioinfusions prevent fetal pulmonary hypoplasia in a large animal model of oligohydramnios. J Pediatr Surg. 2011 Jan; 46(1):67-71.
  7. Turner CG, Klein JD, Steigman SA, Armant M, Nicksa GA, Zurakowski D, Ritz J, Fauza DO. Preclinical regulatory validation of an engineered diaphragmatic tendon made with amniotic mesenchymal stem cells. J Pediatr Surg. 2011 Jan; 46(1):57-61.
  8. Klein JD, Turner CG, Steigman SA, Ahmed A, Zurakowski D, Eriksson E, Fauza DO. Amniotic mesenchymal stem cells enhance normal fetal wound healing. Stem Cells Dev. 2011 Jun; 20(6):969-76.
  9. Steigman SA, Oh JT, Almendinger N, Javid P, LaVan D, Fauza D. Structural and biomechanical characteristics of the diaphragmatic tendon in infancy and childhood: an initial analysis. J Pediatr Surg. 2010 Jul; 45(7):1455-8.
  10. Klein JD, Turner CG, Ahmed A, Steigman SA, Zurakowski D, Fauza DO. Chest wall repair with engineered fetal bone grafts: an efficacy analysis in an autologous leporine model. J Pediatr Surg. 2010 Jun; 45(6):1354-60.
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  12. Nicksa GA, O'Neil E, Yu DC, Curatolo AS, McNeish BL, Barnewolt CE, Zurakowski D, Buchmiller TL, Moses MA, Rosen S, Fauza DO. Correlation between prenatal urinary matrix metalloproteinase activity and the degree of kidney damage in a large animal model of congenital obstructive uropathy. J Pediatr Surg. 2010 Jun; 45(6):1120-5.
  13. Turner CG, Klein JD, Ahmed A, Zurakowski D, Fauza DO. A large animal model of the fetal tracheal stenosis/atresia spectrum. J Surg Res. 2011 Nov; 171(1):164-9.
  14. Nicksa GA, Yu DC, Curatolo AS, McNeish BL, Barnewolt CE, Valim C, Buchmiller TL, Moses MA, Fauza DO. Prenatal urinary matrix metalloproteinase profiling as a potential diagnostic tool in fetal obstructive uropathy. J Pediatr Surg. 2010 Jan; 45(1):70-3.
  15. Steigman SA, Kunisaki SM, Wilkins-Haug L, Takoudes TC, Fauza DO. Optical properties of human amniotic fluid: implications for videofetoscopic surgery. Fetal Diagn Ther. 2010; 27(2):87-90.
  16. Steigman SA, Ahmed A, Shanti RM, Tuan RS, Valim C, Fauza DO. Sternal repair with bone grafts engineered from amniotic mesenchymal stem cells. J Pediatr Surg. 2009 Jun; 44(6):1120-6; discussion 1126.
  17. Turner CG, Fauza DO. Fetal tissue engineering. Clin Perinatol. 2009 Jun; 36(2):473-88, xii.
  18. Modi BP, Ching YA, Langer M, Donovan K, Fauza DO, Kim HB, Jaksic T, Nurko S. Preservation of intestinal motility after the serial transverse enteroplasty procedure in a large animal model of short bowel syndrome. J Pediatr Surg. 2009 Jan; 44(1):229-35; discussion 235.
  19. Fauza DO, Jennings RW, Teng YD, Snyder EY. Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida. Surgery. 2008 Sep; 144(3):367-73.
  20. Kunisaki SM, Fauza DO, Craig N, Jennings RW. Extracorporeal membrane oxygenation as a bridge to definitive tracheal reconstruction in neonates. J Pediatr Surg. 2008 May; 43(5):800-4.
  21. Kunisaki SM, Barnewolt CE, Estroff JA, Nemes LP, Jennings RW, Wilson JM, Fauza DO. Liver position is a prenatal predictive factor of prosthetic repair in congenital diaphragmatic hernia. Fetal Diagn Ther. 2008; 23(4):258-62.
  22. Kunisaki SM, Fuchs JR, Steigman SA, Fauza DO. A comparative analysis of cartilage engineered from different perinatal mesenchymal progenitor cells. Tissue Eng. 2007 Nov; 13(11):2633-44.
  23. Steigman SA, Fauza DO. Isolation of mesenchymal stem cells from amniotic fluid and placenta. Curr Protoc Stem Cell Biol. 2007 Jun; Chapter 1:Unit 1E.2.
  24. Kunisaki SM, Barnewolt CE, Estroff JA, Ward VL, Nemes LP, Fauza DO, Jennings RW. Large fetal congenital cystic adenomatoid malformations: growth trends and patient survival. J Pediatr Surg. 2007 Feb; 42(2):404-10.
  25. Kunisaki SM, Barnewolt CE, Estroff JA, Myers LB, Fauza DO, Wilkins-Haug LE, Grable IA, Ringer SA, Benson CB, Nemes LP, Morash D, Buchmiller TL, Wilson JM, Jennings RW. Ex utero intrapartum treatment with extracorporeal membrane oxygenation for severe congenital diaphragmatic hernia. J Pediatr Surg. 2007 Jan; 42(1):98-104; discussion 104-6.
  26. Barnewolt CE, Kunisaki SM, Fauza DO, Nemes LP, Estroff JA, Jennings RW. Percent predicted lung volumes as measured on fetal magnetic resonance imaging: a useful biometric parameter for risk stratification in congenital diaphragmatic hernia. J Pediatr Surg. 2007 Jan; 42(1):193-7.
  27. Piper H, Modi BP, Kim HB, Fauza D, Glickman J, Jaksic T. The second STEP: the feasibility of repeat serial transverse enteroplasty. J Pediatr Surg. 2006 Dec; 41(12):1951-6.
  28. Kunisaki SM, Azpurua H, Fuchs JR, Graves SC, Zurakowski D, Fauza DO. Fetal hepatic haematopoiesis is modulated by arterial blood flow to the liver. Br J Haematol. 2006 Aug; 134(3):330-2.
  29. Fuchs JR, Nasseri BA, Vacanti JP, Fauza DO. Postnatal myocardial augmentation with skeletal myoblast-based fetal tissue engineering. Surgery. 2006 Jul; 140(1):100-7.
  30. Kunisaki SM, Chang RW, Andreoli S, Lewicke S, Peña-Peterson S, Jennings RW, Fauza DO. Hyperoncotic enhancement of fetal pulmonary growth after tracheal occlusion: an alveolar and capillary morphometric analysis. J Pediatr Surg. 2006 Jul; 41(7):1214-8.
  31. Vogel AM, Smithers CJ, Kozakewich HP, Zurakowski D, Moses MA, Burrows PE, Fauza DO, Fishman SJ. Extracellular matrix dynamics associated with tissue-engineered intravascular sclerotherapy. J Pediatr Surg. 2006 Apr; 41(4):757-62.
  32. Kunisaki SM, Jennings RW, Fauza DO. Fetal cartilage engineering from amniotic mesenchymal progenitor cells. Stem Cells Dev. 2006 Apr; 15(2):245-53.
  33. Kunisaki SM, Freedman DA, Fauza DO. Fetal tracheal reconstruction with cartilaginous grafts engineered from mesenchymal amniocytes. J Pediatr Surg. 2006 Apr; 41(4):675-82; discussion 675-82.
  34. Chang RW, Javid PJ, Oh JT, Andreoli S, Kim HB, Fauza D, Jaksic T. Serial transverse enteroplasty enhances intestinal function in a model of short bowel syndrome. Ann Surg. 2006 Feb; 243(2):223-8.
  35. Kunisaki SM, Fuchs JR, Kaviani A, Oh JT, LaVan DA, Vacanti JP, Wilson JM, Fauza DO. Diaphragmatic repair through fetal tissue engineering: a comparison between mesenchymal amniocyte- and myoblast-based constructs. J Pediatr Surg. 2006 Jan; 41(1):34-9; discussion 34-9.
  36. Terada S, Fuchs JR, Yoshimoto H, Fauza DO, Vacanti JP. In vitro cartilage regeneration from proliferated adult elastic chondrocytes. Ann Plast Surg. 2005 Aug; 55(2):196-201.
  37. Fuchs JR, Hannouche D, Terada S, Zand S, Vacanti JP, Fauza DO. Cartilage engineering from ovine umbilical cord blood mesenchymal progenitor cells. Stem Cells. 2005 Aug; 23(7):958-64.
  38. Sakurai MK, Greene AK, Wilson J, Fauza D, Puder M. Pneumonectomy in the mouse: technique and perioperative management. J Invest Surg. 2005 Jul-Aug; 18(4):201-5.
  39. Smithers CJ, Vogel AM, Kozakewich HP, Freedman DA, Burrows PE, Fauza DO, Fishman SJ. An injectable tissue-engineered embolus prevents luminal recanalization after vascular sclerotherapy. J Pediatr Surg. 2005 Jun; 40(6):920-5.
  40. Smithers CJ, Vogel AM, Kozakewich HP, Freedman DA, Udagawa T, Burrows PE, Fauza DO, Fishman SJ. Enhancement of intravascular sclerotherapy by tissue engineering: short-term results. J Pediatr Surg. 2005 Feb; 40(2):412-7.
  41. Fuchs JR, Kaviani A, Watson K, Thompson J, Wilson JM, Fauza DO. Intratracheal pulmonary ventilation improves gas exchange during laparoscopy in a pediatric lung injury model. J Pediatr Surg. 2005 Jan; 40(1):22-5.
  42. Fauza D. Amniotic fluid and placental stem cells. Best Pract Res Clin Obstet Gynaecol. 2004 Dec; 18(6):877-91.
  43. Garza J, Clayton N, Kaviani A, Maher TJ, Fauza D. In situ inhibition of uterine activity by indomethacin: possible relevance to preterm labor prevention after fetal surgery. J Pediatr Surg. 2004 Aug; 39(8):1173-5.
  44. Fuchs JR, Kaviani A, Oh JT, LaVan D, Udagawa T, Jennings RW, Wilson JM, Fauza DO. Diaphragmatic reconstruction with autologous tendon engineered from mesenchymal amniocytes. J Pediatr Surg. 2004 Jun; 39(6):834-8; discussion 834-8.
  45. Chang R, Komura M, Andreoli S, Jennings R, Wilson J, Fauza D. Rapidly polymerizing hydrogel prevents balloon dislodgement in a model of fetal tracheal occlusion. J Pediatr Surg. 2004 Apr; 39(4):557-60.
  46. Fauza DO, Kohane DS, Beeuwkes EB, Clayton N, Maher TJ. Local anesthetics inhibit uterine activity in vitro. Possible application on preterm labor prevention and treatment. Fetal Diagn Ther. 2003 Sep-Oct; 18(5):292-6.
  47. Fuchs JR, Terada S, Hannouche D, Ochoa ER, Vacanti JP, Fauza DO. Fetal tissue engineering: chest wall reconstruction. J Pediatr Surg. 2003 Aug; 38(8):1188-93.
  48. Fauza DO. Tissue engineering: current state of clinical application. Curr Opin Pediatr. 2003 Jun; 15(3):267-71.
  49. Fuchs JR, Hannouche D, Terada S, Vacanti JP, Fauza DO. Fetal tracheal augmentation with cartilage engineered from bone marrow-derived mesenchymal progenitor cells. J Pediatr Surg. 2003 Jun; 38(6):984-7.
  50. Kim HB, Lee PW, Garza J, Duggan C, Fauza D, Jaksic T. Serial transverse enteroplasty for short bowel syndrome: a case report. J Pediatr Surg. 2003 Jun; 38(6):881-5.
  51. Kaviani A, Guleserian K, Perry TE, Jennings RW, Ziegler MM, Fauza DO. Fetal tissue engineering from amniotic fluid. J Am Coll Surg. 2003 Apr; 196(4):592-7.
  52. Kim HB, Fauza D, Garza J, Oh JT, Nurko S, Jaksic T. Serial transverse enteroplasty (STEP): a novel bowel lengthening procedure. J Pediatr Surg. 2003 Mar; 38(3):425-9.
  53. Garza JJ, Downard CD, Clayton N, Maher TJ, Fauza DO. Clostridium botulinum toxin inhibits myometrial activity in vitro: possible application on the prevention of preterm labor after fetal surgery. J Pediatr Surg. 2003 Mar; 38(3):511-3.
  54. Fuchs JR, Terada S, Hannouche D, Ochoa ER, Vacanti JP, Fauza DO. Engineered fetal cartilage: structural and functional analysis in vitro. J Pediatr Surg. 2002 Dec; 37(12):1720-5.
  55. Fuchs JR, Terada S, Ochoa ER, Vacanti JP, Fauza DO. Fetal tissue engineering: in utero tracheal augmentation in an ovine model. J Pediatr Surg. 2002 Jul; 37(7):1000-6; discussion 1000-6.
  56. Kaviani A, Perry TE, Barnes CM, Oh JT, Ziegler MM, Fishman SJ, Fauza DO. The placenta as a cell source in fetal tissue engineering. J Pediatr Surg. 2002 Jul; 37(7):995-9; discussion 995-9.
  57. Dzakovic A, Kaviani A, Jennings RW, Wilson JM, Fauza DO. Positive intrapulmonary oncotic pressure enhances short-term lung growth acceleration after fetal tracheal occlusion. J Pediatr Surg. 2002 Jul; 37(7):1007-10; discussion 1007-10.
  58. Kaviani A, Perry TE, Dzakovic A, Jennings RW, Ziegler MM, Fauza DO. The amniotic fluid as a source of cells for fetal tissue engineering. J Pediatr Surg. 2001 Nov; 36(11):1662-5.
  59. Fauza DO, Hirschl RB, Wilson JM. Continuous intrapulmonary distension with perfluorocarbon accelerates lung growth in infants with congenital diaphragmatic hernia: initial experience. J Pediatr Surg. 2001 Aug; 36(8):1237-40.
  60. Fauza DO, Marler JJ, Koka R, Forse RA, Mayer JE, Vacanti JP. Fetal tissue engineering: diaphragmatic replacement. J Pediatr Surg. 2001 Jan; 36(1):146-51.
  61. Fauza DO. The littlest patient. Sciences (New York). 1999 Jul-Aug; 39(4):34-8.
  62. Fauza DO, Berde CB, Fishman SJ. Prolonged local myometrial blockade prevents preterm labor after fetal surgery in a leporine model. J Pediatr Surg. 1999 Apr; 34(4):540-2.
  63. Fauza DO, Rawn J, Fishman SJ. Fetal response to neutral gas and liquid media for intraamniotic distension. J Pediatr Surg. 1999 Apr; 34(4):591-4.
  64. Fauza DO, Fishman SJ. Fetal carotid blood flow during videofetoscopy. J Pediatr Surg. 1998 Dec; 33(12):1737-40.
  65. Nobuhara KK, DiFiore JW, Ibla JC, Siddiqui AM, Ferretti ML, Fauza DO, Schnitzer JJ, Wilson JM. Insulin-like growth factor-I gene expression in three models of accelerated lung growth. J Pediatr Surg. 1998 Jul; 33(7):1057-60; discussion 1061.
  66. Nobuhara KK, Fauza DO, DiFiore JW, Hines MH, Fackler JC, Slavin R, Hirschl R, Wilson JM. Continuous intrapulmonary distension with perfluorocarbon accelerates neonatal (but not adult) lung growth. J Pediatr Surg. 1998 Feb; 33(2):292-8.
  67. Fauza DO, Fishman SJ, Mehegan K, Atala A. Videofetoscopically assisted fetal tissue engineering: skin replacement. J Pediatr Surg. 1998 Feb; 33(2):357-61.
  68. Maksoud JG, Fauza DO, Silva MM, Porta G, Miura I, Zerbini CN. Management of biliary atresia in the liver transplantation era: a 15-year, single-center experience. J Pediatr Surg. 1998 Jan; 33(1):115-8.
  69. Fauza DO, Fishman SJ, Mehegan K, Atala A. Videofetoscopically assisted fetal tissue engineering: bladder augmentation. J Pediatr Surg. 1998 Jan; 33(1):7-12.
  70. Wilson JM, Bower LK, Thompson JE, Fauza DO, Fackler JC. ECMO in evolution: the impact of changing patient demographics and alternative therapies on ECMO. J Pediatr Surg. 1996 Aug; 31(8):1116-22; discussion 1122-3.
  71. Lund DP, Soriano SG, Fauza D, Bower L, Jonas R, Hansen DD, Wilson J. Resection of a massive sacrococcygeal teratoma using hypothermic hypoperfusion: a novel use of extracorporeal membrane oxygenation. J Pediatr Surg. 1995 Nov; 30(11):1557-9.
  72. DiFiore JW, Fauza DO, Slavin R, Wilson JM. Experimental fetal tracheal ligation and congenital diaphragmatic hernia: a pulmonary vascular morphometric analysis. J Pediatr Surg. 1995 Jul; 30(7):917-23; discussion 923-4.
  73. Fauza DO, Wilson JM. Congenital diaphragmatic hernia and associated anomalies: their incidence, identification, and impact on prognosis. J Pediatr Surg. 1994 Aug; 29(8):1113-7.
  74. Fauza DO, Tannuri U, Ayoub AA, Capelozzi VL, Saldiva PH, Maksoud JG. Surgically produced congenital diaphragmatic hernia in fetal rabbits. J Pediatr Surg. 1994 Jul; 29(7):882-6.
  75. Wilson JM, Fauza DO, Lund DP, Benacerraf BR, Hendren WH. Antenatal diagnosis of isolated congenital diaphragmatic hernia is not an indicator of outcome. J Pediatr Surg. 1994 Jun; 29(6):815-9.
  76. DiFiore JW, Fauza DO, Slavin R, Peters CA, Fackler JC, Wilson JM. Experimental fetal tracheal ligation reverses the structural and physiological effects of pulmonary hypoplasia in congenital diaphragmatic hernia. J Pediatr Surg. 1994 Feb; 29(2):248-56; discussion 256-7.
  77. Maksoud JG, Chapchap P, Porta G, Miura I, Carone Filho E, Tannuri U, da Silva MM, Ayoub AA, Santos MM, Fauza Dde O, et al. [Liver transplantation in children: initial experience of the Instituto da Criança of the Hospital das Clínicas of Universidade de São Paulo]. AMB Rev Assoc Med Bras. 1991 Oct-Dec; 37(4):193-9.
  78. Fauza Dde O, Maksoud Filho JG, el Ibrahim R. [Acute abdomen in childhood caused by intestinal angiostrongylus infection: a case report]. AMB Rev Assoc Med Bras. 1990 Jul-Dec; 36(3-4):150-2.
  79. Fauza Dde O. [A new cannula for tracheostomy]. Rev Hosp Clin Fac Med Sao Paulo. 1988 Nov-Dec; 43(6):291-3.
  80. Rodrigues Júnior AJ, Bevilacqua RG, Fauza Dde O, de Carvalho CA. [Prevention of tracheo-innominate fistula following tracheostomy: anatomic relations of the trachea and brachiocephalic trunk]. Rev Hosp Clin Fac Med Sao Paulo. 1988 Jan-Feb; 43(1):71-4.
  81. Fuchs JR, Pomerantseva I, Ochoa ER, Vacanti JP, Fauza DO. Fetal tissue engineering: in vitro analysis of muscle constructs. J Pediatr Surg. 2003 Sep; 38(9):1348-53.
  82. Chang R, Komura M, Andreoli S, Klingenberg M, Jennings R, Wilson J, Fauza D. Hyperoncotic enhancement of pulmonary growth after fetal tracheal occlusion: a comparison between dextran and albumin. J Pediatr Surg. 2004 Mar; 39(3):324-8; discussion 324-8.
  83. Fauza DO, Barnewolt C, Brown SD, Jennings RW. Ultrasound-guided fetal tracheal occlusion. J Pediatr Surg. 2002 Mar; 37(3):300-2.
  84. Kunisaki SM, Fauza DO, Barnewolt CE, Estroff JA, Myers LB, Bulich LA, Wong G, Levine D, Wilkins-Haug LE, Benson CB, Jennings RW. Ex utero intrapartum treatment with placement on extracorporeal membrane oxygenation for fetal thoracic masses. J Pediatr Surg. 2007 Feb; 42(2):420-5.
  85. Kunisaki SM, Armant M, Kao GS, Stevenson K, Kim H, Fauza DO. Tissue engineering from human mesenchymal amniocytes: a prelude to clinical trials. J Pediatr Surg. 2007 Jun; 42(6):974-9; discussion 979-80.
  86. Steigman SA, Armant M, Bayer-Zwirello L, Kao GS, Silberstein L, Ritz J, Fauza DO. Preclinical regulatory validation of a 3-stage amniotic mesenchymal stem cell manufacturing protocol. J Pediatr Surg. 2008 Jun; 43(6):1164-9.
  87. Levy MS, Share JC, Fauza DO, Wilson JM. Fate of the reconstructed carotid artery after extracorporeal membrane oxygenation. J Pediatr Surg. 1995 Jul; 30(7):1046-9.
  88. Kunisaki SM, Fauza DO, Nemes LP, Barnewolt CE, Estroff JA, Kozakewich HP, Jennings RW. Bronchial atresia: the hidden pathology within a spectrum of prenatally diagnosed lung masses. J Pediatr Surg. 2006 Jan; 41(1):61-5; discussion 61-5.
  89. Steigman SA, Nemes L, Barnewolt CE, Estroff JA, Valim C, Jennings RW, Fauza DO. Differential risk for neonatal surgical airway intervention in prenatally diagnosed neck masses. J Pediatr Surg. 2009 Jan; 44(1):76-9.
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