Research

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Carolyn Bridgemohan, MD

Carolyn Bridgemohan
Department:
Medicine Research
Division
Developmental Medicine Research
Hospital Title:
Associate in Medicine
Academic Title:
Assistant Professor of Pediatrics, Harvard Medical School
Research Focus Area:
Autism Spectrum Disorders
Contact:
617-355-7249

Research Overview

Dr. Bridgemohan's research is focused on clinical care of children with autism spectrum disorder. Current projects include a multisite study to identify early markers of ASD and pilot the collection of data within the setting of the clinical visit across diverse clinical units. One goal of this work is to evaluate the feasibility of combining clinical care with research in a population of children who often have difficulty participating due to their communication, behavioral and sensory challenges. The second goal is to identify measurable biomarkers (such as substances in the blood and urine) that could predict risk for ASD or identify subgroups of children with ASD and thus lead to earlier diagnosis and more targeted treatments.

Dr. Bridgemohan is the co-director of Boston Children's Hospital Autism Spectrum Center, a multi-departmental and multidisciplinary center providing diagnosis, treatment, continuity of care and support services for children with ASD and their families. Projects in the Autism Spectrum Center's Autism Friendly Hospital initiative include developing materials to improve children's preparation for and experience with hospital visits and procedures, educational training modules for staff to improve awareness of ASD and quality of care throughout the institution, and a periodic survey of patients to identify barriers to care encountered by this patient population.

Two related research projects focus on development of outcomes measures as there are currently no widely accepted measures of outcome for children with ASD used in research or clinical practice. The first involves development a parent reported outcomes monitoring tool to allow monitoring of clinical and developmental progress over time. The second involves validating items from the NIH PROMIS quality of life measures in children with ASD.

Dr. Bridgemohan received her MD from Brown University. She completed her pediatric residency at Children's Hospital of Philadelphia and her fellowship at Boston Children's Hospital.



Publications

Publications powered by Harvard Catalyst Profiles
  1. Bickel J, Bridgemohan C, Sideridis G, Huntington N. Child and family characteristics associated with age of diagnosis of an autism spectrum disorder in a tertiary care setting. J Dev Behav Pediatr. 2015 Jan; 36(1):1-7.
  2. Schonwald A, Huntington N, Chan E, Risko W, Bridgemohan C. Routine developmental screening implemented in urban primary care settings: more evidence of feasibility and effectiveness. Pediatrics. 2009 Feb; 123(2):660-8.
  3. Miller DT, Shen Y, Weiss LA, Korn J, Anselm I, Bridgemohan C, Cox GF, Dickinson H, Gentile J, Harris DJ, Hegde V, Hundley R, Khwaja O, Kothare S, Luedke C, Nasir R, Poduri A, Prasad K, Raffalli P, Reinhard A, Smith SE, Sobeih MM, Soul JS, Stoler J, Takeoka M, Tan WH, Thakuria J, Wolff R, Yusupov R, Gusella JF, Daly MJ, Wu BL. Microdeletion/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders. J Med Genet. 2009 Apr; 46(4):242-8.
  4. Bridgemohan CF, Levy S, Veluz AK, Knight JR. Teaching paediatric residents about learning disorders: use of standardised case discussion versus multimedia computer tutorial. Med Educ. 2005 Aug; 39(8):797-806.
  5. Schonwald A, Sherritt L, Stadtler A, Bridgemohan C. Factors associated with difficult toilet training. Pediatrics. 2004 Jun; 113(6):1753-7.
  6. Handelman L, Rich M, Bridgemohan CF, Schneider L. Understanding pediatric inner-city asthma: an explanatory model approach. J Asthma. 2004 Apr; 41(2):167-77.
  7. Shen Y, Dies KA, Holm IA, Bridgemohan C, Sobeih MM, Caronna EB, Miller KJ, Frazier JA, Silverstein I, Picker J, Weissman L, Raffalli P, Jeste S, Demmer LA, Peters HK, Brewster SJ, Kowalczyk SJ, Rosen-Sheidley B, McGowan C, Duda AW, Lincoln SA, Lowe KR, Schonwald A, Robbins M, Hisama F, Wolff R, Becker R, Nasir R, Urion DK, Milunsky JM, Rappaport L, Gusella JF, Walsh CA, Wu BL, Miller DT. Clinical genetic testing for patients with autism spectrum disorders. Pediatrics. 2010 Apr; 125(4):e727-35.
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