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Asim A.  Ahmed, MD

Medicine Research
Infectious Diseases Research
Hospital Title:
Assistant in Medicine
Academic Title:
Instructor in Medicine, Harvard Medical School
Research Focus Area:
Molecular mechanisms of viral entry, Host determinants of viral entry, Mosquito-borne viruses, Encephalitis, Emerging viruses
Contact Via Email
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Research Overview

Asim A. Ahmed has a long-standing interest in re-emerging pathogens, mosquito-borne viruses and molecular mechanisms of viral entry. Most recently he has focused on a domestic arbovirus called Eastern Equine Encephalitis virus (EEEV), which causes highly pathogenic, often fatal brain infection in humans and horses. He has been investigating the host factors that are required for EEEV infection. The approach involves utilizing genome-wide loss of function screens to identify host factors that are necessary for EEEV infection into host cells.

About Dr. Ahmed

Asim A. Ahmed is a native of St. Louis, Missouri and obtained his B.A. in Anthropology and Neuroscience from Amherst College. He obtained his M.D. from Baylor College of Medicine and performed an HHMI medical student research fellowship at UCSF. He completed his residency in pediatrics at The Children’s Hospital of Philadelphia and fellowship in pediatric infectious diseases at Boston Children’s Hospital.


Publications powered by Harvard Catalyst Profiles
  1. Gauguet S, Ahmed AA, Zhou J, Pfoh ER, Ahnger-Pier KK, Harper MB, Ozonoff A, Wessels MR, Lee GM. Group A streptococcal bacteremia without a source is associated with less severe disease in children. Pediatr Infect Dis J. 2015 Apr; 34(4):447-9.
  2. Jemielity S, Wang JJ, Chan YK, Ahmed AA, Li W, Monahan S, Bu X, Farzan M, Freeman GJ, Umetsu DT, Dekruyff RH, Choe H. TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine. PLoS Pathog. 2013 Mar; 9(3):e1003232.
  3. Silverman MA, Misasi J, Smole S, Feldman HA, Cohen AB, Santagata S, McManus M, Ahmed AA. Eastern equine encephalitis in children, Massachusetts and New Hampshire,USA, 1970-2010. Emerg Infect Dis. 2013 Feb; 19(2):194-201; quiz 352.
  4. Flett K, Youngster I, Huang J, McAdam A, Sandora TJ, Rennick M, Smole S, Rogers SL, Nix WA, Oberste MS, Gellis S, Ahmed AA. Hand, foot, and mouth disease caused by coxsackievirus a6. Emerg Infect Dis. 2012 Oct; 18(10):1702-4.
  5. Kwong JA, Dorfman T, Quinlan BD, Chiang JJ, Ahmed AA, Choe H, Farzan M. A tyrosine-sulfated CCR5-mimetic peptide promotes conformational transitions in the HIV-1 envelope glycoprotein. J Virol. 2011 Aug; 85(15):7563-71.
  6. Huang IC, Bailey CC, Weyer JL, Radoshitzky SR, Becker MM, Chiang JJ, Brass AL, Ahmed AA, Chi X, Dong L, Longobardi LE, Boltz D, Kuhn JH, Elledge SJ, Bavari S, Denison MR, Choe H, Farzan M. Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus. PLoS Pathog. 2011; 7(1):e1001258.
  7. Fox LM, Wingerter S, Ahmed A, Arnold A, Chou J, Rhein L, Levy O. Neonatal babesiosis: case report and review of the literature. Pediatr Infect Dis J. 2006 Feb; 25(2):169-73.
  8. Pierson TC, Sánchez MD, Puffer BA, Ahmed AA, Geiss BJ, Valentine LE, Altamura LA, Diamond MS, Doms RW. A rapid and quantitative assay for measuring antibody-mediated neutralization of West Nile virus infection. Virology. 2006 Mar 1; 346(1):53-65.
  9. Ahmed AA, McFalls JM, Hoffmann C, Filone CM, Stewart SM, Paragas J, Khodjaev S, Shermukhamedova D, Schmaljohn CS, Doms RW, Bertolotti-Ciarlet A. Presence of broadly reactive and group-specific neutralizing epitopes on newly described isolates of Crimean-Congo hemorrhagic fever virus. J Gen Virol. 2005 Dec; 86(Pt 12):3327-36.
  10. Hanna SL, Pierson TC, Sanchez MD, Ahmed AA, Murtadha MM, Doms RW. N-linked glycosylation of west nile virus envelope proteins influences particle assembly and infectivity. J Virol. 2005 Nov; 79(21):13262-74.
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  12. Elia J, Dell ML, Friedman DF, Zimmerman RA, Balamuth N, Ahmed AA, Pati S. PANDAS with catatonia: a case report. Therapeutic response to lorazepam and plasmapheresis. J Am Acad Child Adolesc Psychiatry. 2005 Nov; 44(11):1145-50.
  13. Holden KL, Stein DA, Pierson TC, Ahmed AA, Clyde K, Iversen PL, Harris E. Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure. Virology. 2006 Jan 20; 344(2):439-52.
  14. Pierson TC, Diamond MS, Ahmed AA, Valentine LE, Davis CW, Samuel MA, Hanna SL, Puffer BA, Doms RW. An infectious West Nile virus that expresses a GFP reporter gene. Virology. 2005 Mar 30; 334(1):28-40.
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