Research

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Aditya “AK" Kaza, MD

AK Kaza MD
Department:
Cardiac Surgery Research
Hospital Title:
Attending in Cardiac Surgery
Academic Title:
Assistant Professor, Harvard Medical School

Publications

Publications powered by Harvard Catalyst Profiles
  1. Kaza AK. Are attempts at regulating flow through systemic-to-pulmonary arterial shunts still valid? J Thorac Cardiovasc Surg. 2016 Nov; 152(5):1353-1354.
  2. Kaza AK, Thiagarajan RR. Left Ventricular Outflow Tract Obstruction: Coarctation of the Aorta, Interrupted Aortic Arch, and Borderline Left Ventricle. Pediatr Crit Care Med. 2016 Aug; 17(8 Suppl 1):S315-7.
  3. Kaza AK. Techniques to aid pulmonary valve preservation during repair of tetralogy of Fallot. J Thorac Cardiovasc Surg. 2016 Jun; 151(6):1759.
  4. Huang C, Sachse FB, Hitchcock RW, Kaza AK. Sensitivity and Specificity of Cardiac Tissue Discrimination Using Fiber-Optics Confocal Microscopy. PLoS One. 2016; 11(1):e0147667.
  5. Kaza AK, Pigula FA. Are Bioprosthetic Valves Appropriate for Aortic Valve Replacement in Young Patients? Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2016; 19(1):63-7.
  6. Kaza AK. Heart transplantation in patients who have congenital heart disease and single-lung physiology. J Thorac Cardiovasc Surg. 2015 Dec; 150(6):1473.
  7. Kaza AK, Pigula FA. Surgical approaches to critical aortic stenosis with unicommissural valve in neonates. Expert Rev Cardiovasc Ther. 2014 Dec; 12(12):1401-5.
  8. Huang C, Kaza AK, Hitchcock RW, Sachse FB. Local delivery of fluorescent dye for fiber-optics confocal microscopy of the living heart. Front Physiol. 2014; 5:367.
  9. Kaza AK. Fontan modification with a Y-graft. J Thorac Cardiovasc Surg. 2015 Jan; 149(1):246.
  10. Loftus PD, Arrington CB, Kaza AK. Neonatal flail tricuspid valve: diagnosis and management. Ann Thorac Surg. 2014 Sep; 98(3):1098-101.
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  12. Kaza AK, Kaza E, Bullock E, Reyna S, Yetman A, Everitt MD. Pulmonary vascular remodelling after heart transplantation in patients with cavopulmonary connection. Eur J Cardiothorac Surg. 2015 Mar; 47(3):505-10; discussion 510.
  13. Boucek D, Yetman AT, Yeung E, Miyamoto SD, Stehlik J, Kfoury AG, Kaza AK, Weng C, Everitt MD. Survival based on patient selection for heart transplant in adults with congenital heart disease: a multi-institutional study. Int J Cardiol. 2014; 172(1):e89-90.
  14. Kaza AK, Gruber PJ. Surgical approaches for CHD: and update on success and challenges. Curr Opin Pediatr. 2013 Oct; 25(5):591-6.
  15. Huang C, Kaza AK, Hitchcock RW, Sachse FB. Identification of nodal tissue in the living heart using rapid scanning fiber-optics confocal microscopy and extracellular fluorophores. Circ Cardiovasc Imaging. 2013 Sep; 6(5):739-46.
  16. Atz AM, Travison TG, McCrindle BW, Mahony L, Glatz AC, Kaza AK, Breitbart RE, Colan SD, Kaltman JR, Margossian R, Pasquali SK, Wang Y, Gersony WM. Cardiac performance and quality of life in patients who have undergone the Fontan procedure with and without prior superior cavopulmonary connection. Cardiol Young. 2013 Jun; 23(3):335-43.
  17. Menon SC, Kaza AK, Puchalski MD. Effect of ventricular size and function on exercise performance and the electrocardiogram in repaired tetralogy of Fallot with pure pulmonary regurgitation. Ann Pediatr Cardiol. 2012 Jul; 5(2):151-5.
  18. Pasquali SK, Ohye RG, Lu M, Kaltman J, Caldarone CA, Pizarro C, Dunbar-Masterson C, Gaynor JW, Jacobs JP, Kaza AK, Newburger J, Rhodes JF, Scheurer M, Silver E, Sleeper LA, Tabbutt S, Tweddell J, Uzark K, Wells W, Mahle WT, Pearson GD. Variation in perioperative care across centers for infants undergoing the Norwood procedure. J Thorac Cardiovasc Surg. 2012 Oct; 144(4):915-21.
  19. Everitt MD, Hammond ME, Snow GL, Stehlik J, Revelo MP, Miller DV, Kaza AK, Budge D, Alharethi R, Molina KM, Kfoury AG. Biopsy-diagnosed antibody-mediated rejection based on the proposed International Society for Heart and Lung Transplantation working formulation is associated with adverse cardiovascular outcomes after pediatric heart transplant. J Heart Lung Transplant. 2012 Jul; 31(7):686-93.
  20. Everitt MD, Boyle GJ, Schechtman KB, Zheng J, Bullock EA, Kaza AK, Dipchand AI, Naftel DC, Kirklin JK, Canter CE. Early survival after heart transplant in young infants is lowest after failed single-ventricle palliation: a multi-institutional study. J Heart Lung Transplant. 2012 May; 31(5):509-16.
  21. Mart CR, Kaza AK. Postoperative dissecting ventricular septal hematoma: recognition and treatment. ISRN Pediatr. 2011; 2011:534940.
  22. Everitt MD, Donaldson AE, Stehlik J, Kaza AK, Budge D, Alharethi R, Bullock EA, Kfoury AG, Yetman AT. Would access to device therapies improve transplant outcomes for adults with congenital heart disease? Analysis of the United Network for Organ Sharing (UNOS). J Heart Lung Transplant. 2011 Apr; 30(4):395-401.
  23. Burch PT, Kaza AK, Lambert LM, Holubkov R, Shaddy RE, Hawkins JA. Clinical performance of decellularized cryopreserved valved allografts compared with standard allografts in the right ventricular outflow tract. Ann Thorac Surg. 2010 Oct; 90(4):1301-5; discussion 1306.
  24. Hawkins JA, Kaza AK, Burch PT, Lambert LM, Holubkov R, Witte MK. Simple versus complex truncus arteriosus: neutralization of risk but with increased resource utilization. World J Pediatr Congenit Heart Surg. 2010 Oct; 1(3):285-91.
  25. Lemoine TJ, Kaza AK, Gray R, Day RW, Tani LY, Poss WB. Anomalous origin of the left coronary artery from the pulmonary artery in Alagille syndrome. Congenit Heart Dis. 2010 Sep-Oct; 5(5):462-4.
  26. Kouretas PC, Kaza AK, Burch PT, Witte MK, Clayson SE, Everitt MD, Selzman CH. Experience with the Levitronix CentriMag in the pediatric population as a bridge to decision and recovery. Artif Organs. 2009 Nov; 33(11):1002-4.
  27. Kouretas PC, Burch PT, Kaza AK, Lambert LM, Witte MK, Everitt MD, Siddiqi FA. Management of deep wound complications with vacuum-assisted therapy after Berlin Heart EXCOR ventricular assist device placement in the pediatric population. Artif Organs. 2009 Nov; 33(11):922-5.
  28. Everitt MD, Donaldson AE, Casper TC, Stehlik J, Hawkins JA, Tani LY, Renlund DG, Kouretas PC, Kaza AK, Bullock EA, Cardon M, Kfoury AG. Effect of ABO-incompatible listing on infant heart transplant waitlist outcomes: analysis of the United Network for Organ Sharing (UNOS) database. J Heart Lung Transplant. 2009 Dec; 28(12):1254-60.
  29. Griffiths ER, Kaza AK, Wyler von Ballmoos MC, Loyola H, Valente AM, Blume ED, del Nido P. Evaluating failing Fontans for heart transplantation: predictors of death. Ann Thorac Surg. 2009 Aug; 88(2):558-63; discussion 563-4.
  30. Kaza AK, Lim HG, Dibardino DJ, Bautista-Hernandez V, Robinson J, Allan C, Laussen P, Fynn-Thompson F, Bacha E, del Nido PJ, Mayer JE, Pigula FA. Long-term results of right ventricular outflow tract reconstruction in neonatal cardiac surgery: options and outcomes. J Thorac Cardiovasc Surg. 2009 Oct; 138(4):911-6.
  31. DiBardino DJ, McElhinney DB, Kaza AK, Mayer JE. Analysis of the US Food and Drug Administration Manufacturer and User Facility Device Experience database for adverse events involving Amplatzer septal occluder devices and comparison with the Society of Thoracic Surgery congenital cardiac surgery database. J Thorac Cardiovasc Surg. 2009 Jun; 137(6):1334-41.
  32. Hawkins JA, Sower CT, Lambert LM, Kouretas PC, Burch PT, Kaza AK, Puchalski MD, Yetman AT. Stentless porcine valves in the right ventricular outflow tract: improved durability? Eur J Cardiothorac Surg. 2009 Apr; 35(4):600-4; discussion 604-5.
  33. Bautista-Hernandez V, Kaza AK, Benavidez OJ, Pigula FA. True aneurysmal dilatation of a contegra conduit after right ventricular outflow tract reconstruction: a novel mechanism of conduit failure. Ann Thorac Surg. 2008 Dec; 86(6):1976-7.
  34. Tissot C, Darst JR, Kaza AK, Younoszai AK, da Cruz E. Partial left pulmonary artery sling associated with multiple ventricular septal defects: a rare congenital anomaly. J Thorac Cardiovasc Surg. 2008 Oct; 136(4):1085-7.
  35. Kaza AK, Mitchell JD. Preoperative pulmonary evaluation of the thoracic surgical patient. Thorac Surg Clin. 2005 May; 15(2):297-304.
  36. Long SM, Laubach VE, Tribble CG, Kaza AK, Fiser SM, Cassada DC, Kern JA, Kron IL. Pyrrolidine dithiocarbamate reduces lung reperfusion injury. J Surg Res. 2003 Jun 1; 112(1):12-8.
  37. Kaza AK, Cope JT, Fiser SM, Long SM, Kern JA, Kron IL, Tribble CG. Elimination of fat microemboli during cardiopulmonary bypass. Ann Thorac Surg. 2003 Feb; 75(2):555-9; discussion 559.
  38. Long SM, Tribble CG, Raymond DP, Fiser SM, Kaza AK, Kern JA, Kron IL. Preoperative shock determines outcome for acute type A aortic dissection. Ann Thorac Surg. 2003 Feb; 75(2):520-4.
  39. Fiser SM, Tribble CG, Kaza AK, Long SM, Kern JA, Cassada DC, Linden J, Rieger J, Laubach VE, Matisoff A, Kron IL. Adenosine A2A receptor activation decreases reperfusion injury associated with high-flow reperfusion. J Thorac Cardiovasc Surg. 2002 Nov; 124(5):973-8.
  40. Kaza AK, Kron IL, Leuwerke SM, Tribble CG, Laubach VE. Keratinocyte growth factor enhances post-pneumonectomy lung growth by alveolar proliferation. Circulation. 2002 Sep 24; 106(12 Suppl 1):I120-4.
  41. Cassada DC, Tribble CG, Long SM, Kaza AK, Linden J, Rieger JM, Rosin D, Kron IL, Kern JA. Adenosine A2A agonist reduces paralysis after spinal cord ischemia: correlation with A2A receptor expression on motor neurons. Ann Thorac Surg. 2002 Sep; 74(3):846-9; discussion 849-50.
  42. Fiser SM, Kron IL, Long SM, Kaza AK, Kern JA, Cassada DC, Laubach VE, Tribble CG. Controlled perfusion decreases reperfusion injury after high-flow reperfusion. J Heart Lung Transplant. 2002 Jun; 21(6):687-91.
  43. Kaza AK, Patel MR, Fiser SM, Long SM, Kern JA, Tribble CG, Kron IL. Ventricular reconstruction results in improved left ventricular function and amelioration of mitral insufficiency. Ann Surg. 2002 Jun; 235(6):828-32.
  44. Leuwerke SM, Kaza AK, Tribble CG, Kron IL, Laubach VE. Inhibition of compensatory lung growth in endothelial nitric oxide synthase-deficient mice. Am J Physiol Lung Cell Mol Physiol. 2002 Jun; 282(6):L1272-8.
  45. Kaza AK, Tribble CG, Crosby IK. Repair of an anomalous left coronary artery. Cardiovasc Surg. 2002 Jun; 10(3):276-8.
  46. Cassada DC, Tribble CG, Long SM, Laubach VE, Kaza AK, Linden J, Nguyen BN, Rieger JM, Fiser SM, Kron IL, Kern JA. Adenosine A2A analogue ATL-146e reduces systemic tumor necrosing factor-alpha and spinal cord capillary platelet-endothelial cell adhesion molecule-1 expression after spinal cord ischemia. J Vasc Surg. 2002 May; 35(5):994-8.
  47. Fiser SM, Tribble CG, Long SM, Kaza AK, Kern JA, Jones DR, Robbins MK, Kron IL. Ischemia-reperfusion injury after lung transplantation increases risk of late bronchiolitis obliterans syndrome. Ann Thorac Surg. 2002 Apr; 73(4):1041-7; discussion 1047-8.
  48. Kaza AK, Dietz JF, Kern JA, Jones DR, Robbins MK, Fiser SM, Long SM, Bergin JD, Kron IL, Tribble CG. Coronary risk stratification in patients with end-stage lung disease. J Heart Lung Transplant. 2002 Mar; 21(3):334-9.
  49. Kaza AK, Cope JT, Fiser SM, Long SM, Kern JA, Tribble CG, Kron IL, Laubach VE. Contrasting natures of lung growth after transplantation and lobectomy. J Thorac Cardiovasc Surg. 2002 Feb; 123(2):288-94.
  50. Kaza AK, Buchanan SA, Parrino GP, Fiser SM, Long SM, Tribble CG. Cardioscope-assisted excision of a left ventricular tumor--a case report. Heart Surg Forum. 2002; 5(1):75-6.
  51. Fiser SM, Kron IL, Long SM, Kaza AK, Robbins M, Kern JA, Tribble CG. Donor lung salvage after neurogenic pulmonary edema with the use of post-transplant extracorporeal membrane oxygenation. J Thorac Cardiovasc Surg. 2001 Dec; 122(6):1257-8.
  52. Fiser SM, Kron IL, Long SM, Kaza AK, Kern JA, Cassada DC, Jones DR, Robbins MC, Tribble CG. Influence of graft ischemic time on outcomes following lung transplantation. J Heart Lung Transplant. 2001 Dec; 20(12):1291-6.
  53. Cope JT, Kaza AK, Reade CC, Shockey KS, Kern JA, Tribble CG, Kron IL. A cost comparison of heart transplantation versus alternative operations for cardiomyopathy. Ann Thorac Surg. 2001 Oct; 72(4):1298-305.
  54. Cassada DC, Gangemi JJ, Rieger JM, Linden J, Kaza AK, Long SM, Kron IL, Tribble CG, Kern JA. Systemic adenosine A2A agonist ameliorates ischemic reperfusion injury in the rabbit spinal cord. Ann Thorac Surg. 2001 Oct; 72(4):1245-50.
  55. Patel MR, Buchanan SA, Bergin JD, Fiser SM, Kaza AK, Tribble CG. As originally published in 1994: Ambulatory intraaortic balloon counterpulsation. Updated in 2001. Ann Thorac Surg. 2001 Sep; 72(3):975.
  56. Cassada DC, Tribble CG, Laubach VE, Nguyen BN, Rieger JM, Linden J, Kaza AK, Long SM, Kron IL, Kern JA. An adenosine A2A agonist, ATL-146e, reduces paralysis and apoptosis during rabbit spinal cord reperfusion. J Vasc Surg. 2001 Sep; 34(3):482-8.
  57. Cassada DC, Tribble CG, Kaza AK, Fiser SM, Long SM, Linden J, Rieger JM, Kron IL, Kern JA. Adenosine analogue reduces spinal cord reperfusion injury in a time-dependent fashion. Surgery. 2001 Aug; 130(2):230-5.
  58. Kaza AK, Cope JT, Kern JA, Cassada DC, Long SM, Fiser SM, Kron IL, Tribble CG. A technique for adequate coverage of the proximal suture line during abdominal aortic aneurysm repair. J Vasc Surg. 2001 Aug; 34(2):367-8.
  59. Kaza AK, Kron IL, Long SM, Fiser SM, Stevens PM, Kern JA, Tribble CG, Laubach VE. Epidermal growth factor receptor up-regulation is associated with lung growth after lobectomy. Ann Thorac Surg. 2001 Aug; 72(2):380-5.
  60. Fiser SM, Tribble CG, Kern JA, Long SM, Kaza AK, Kron IL. Cardiac reoperation in the intensive care unit. Ann Thorac Surg. 2001 Jun; 71(6):1888-92; discussion 1892-3.
  61. Fiser SM, Kron IL, McLendon Long S, Kaza AK, Kern JA, Tribble CG. Early intervention after severe oxygenation index elevation improves survival following lung transplantation. J Heart Lung Transplant. 2001 Jun; 20(6):631-6.
  62. Fiser SM, Tribble CG, Long SM, Kaza AK, Cope JT, Laubach VE, Kern JA, Kron IL. Lung transplant reperfusion injury involves pulmonary macrophages and circulating leukocytes in a biphasic response. J Thorac Cardiovasc Surg. 2001 Jun; 121(6):1069-75.
  63. Kaza AK, Kron IL, Kern JA, Long SM, Fiser SM, Nguyen RP, Tribble CG, Laubach VE. Retinoic acid enhances lung growth after pneumonectomy. Ann Thorac Surg. 2001 May; 71(5):1645-50.
  64. Fiser SM, Cope JT, Kron IL, Kaza AK, Long SM, Kern JA, Tribble CG, Lowson SM. Aerosolized prostacyclin (epoprostenol) as an alternative to inhaled nitric oxide for patients with reperfusion injury after lung transplantation. J Thorac Cardiovasc Surg. 2001 May; 121(5):981-2.
  65. Fiser SM, Tribble CG, Long SM, Kaza AK, Kern JA, Kron IL. Pulmonary macrophages are involved in reperfusion injury after lung transplantation. Ann Thorac Surg. 2001 Apr; 71(4):1134-8; discussion 1138-9.
  66. Fiser SM, Kron IL, Long SM, Kaza AK, Kern JA, Tribble CG. Influence of graft ischemia time on outcomes following lung transplantation. J Heart Lung Transplant. 2001 Feb; 20(2):206-207.
  67. Fiser SM, Tribble CG, Kern JA, Long SM, Kaza AK, Kron IL. Controlled perfusion decreases lung transplant reperfusion injury in the setting of high flow reperfusion. J Heart Lung Transplant. 2001 Feb; 20(2):183.
  68. Hersh RE, Kaza AK, Long SM, Fiser SM, Drake DB, Tribble CG. A technique for the treatment of sternal infections using the Vacuum Assisted Closure device. Heart Surg Forum. 2001; 4(3):211-5.
  69. Fiser SM, Tribble CG, Kaza AK, Long SM, Zacour RK, Kern JA, Kron IL. When to discontinue extracorporeal membrane oxygenation for postcardiotomy support. Ann Thorac Surg. 2001 Jan; 71(1):210-4.
  70. Long SM, Peeler BB, Fiser SM, Kaza AK, Tribble CG. Xenotransplantation update. Heart Surg Forum. 2001; 4(3):261-5.
  71. Fiser SM, Wood HE, Allaire PE, Long J, Diegel P, Long SM, Kaza AK, Kron IL, Kern JA, Tribble CG. A long-term ventricular assist device utilizing a magnetic bearing system and implantable physiologic controller. Heart Surg Forum. 2001; 4(1):11-2.
  72. Kaza AK, Laubach VE, Kern JA, Long SM, Fiser SM, Tepper JA, Nguyen RP, Shockey KS, Tribble CG, Kron IL. Epidermal growth factor augments postpneumonectomy lung growth. J Thorac Cardiovasc Surg. 2000 Nov; 120(5):916-21.
  73. Kaza AK, Burch PT, Pinto N, Minich LL, Tani LY, Hawkins JA. Durability of truncal valve repair. Ann Thorac Surg. 2010 Oct; 90(4):1307-12; discussion 1312.
  74. Kaza E, Marx GR, Kaza AK, Colan SD, Loyola H, Perrin DP, Del Nido PJ. Changes in left atrioventricular valve geometry after surgical repair of complete atrioventricular canal. J Thorac Cardiovasc Surg. 2012 May; 143(5):1117-24.
  75. Kaza AK, Colan SD, Jaggers J, Lu M, Atz AM, Sleeper LA, McCrindle BW, Lambert LM, Margossian R, Lacro RV, Richmond ME, Natarajan S, Minich LL. Surgical interventions for atrioventricular septal defect subtypes: the pediatric heart network experience. Ann Thorac Surg. 2011 Oct; 92(4):1468-75; discussion 1475.
  76. Long SM, Kern JA, Fiser SM, Kaza AK, Cassada DC, Miller BT, Claridge JA, Kron IL, Tribble CG. Carotid arteriography impacts carotid stenosis management. Vasc Surg. 2001 Jul-Aug; 35(4):251-6; discussion 257.
  77. Mauney MM, Cassada DC, Kaza AK, Long SM, Kern JA. Management of innominate artery injury in the setting of bovine arch anomaly. Ann Thorac Surg. 2001 Dec; 72(6):2134-6.
  78. Loftus PD, Erickson LK, Everitt MD, Kaza AK. Heart failure due to "disappearing" aortic valve in hypoplastic left heart syndrome. World J Pediatr Congenit Heart Surg. 2014 Apr; 5(2):334-7.
  79. Emani S, Kaza AK, Almodovar M, Thiagarajan R, Emani SM. Intravenous GPIIb/IIIa Inhibitor for Secondary Prevention of Shunt Thrombosis in a Pediatric Patient. Ann Thorac Surg. 2015 Jun; 99(6):e151-3.
  80. Kaza AK. The need for personalized resuscitation guidelines in children with congenital heart disease. J Thorac Cardiovasc Surg. 2016 Oct 24.
  81. Mills KI, Kaza AK, Walsh BK, Bond HC, Ford M, Wypij D, Thiagarajan RR, Almodovar MC, Quinonez LG, Baird CW, Emani SE, Pigula FA, DiNardo JA, Kheir JN. Phosphodiesterase Inhibitor-Based Vasodilation Improves Oxygen Delivery and Clinical Outcomes Following Stage 1 Palliation. J Am Heart Assoc. 2016 Nov 2; 5(11).
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