Abby Fleisch’s research is focused on the extent to which environmental toxicants impact endocrine outcomes such as growth, obesity and insulin resistance.
She has used data from the Russian Children’s Study (~400 peripubertal boys) to identify inhibition of the hypothalamic pituitary growth axis as a pathway through which lead exposure may impair childhood growth. She has evaluated the use of bisphenol A in dental materials and reviewed the role of environmental epigenetics in endocrine disease.
Her current projects are nested within the Project Viva pre-birth cohort (~2,100 Boston-area women and their offspring). She has demonstrated that higher ambient air pollution exposure during pregnancy is associated with maternal hyperglycemia, low fetal growth, and rapid infant weight gain, a milieu that may prime children for obesity and insulin resistance later in life. Her ongoing studies (1) examine the extent to which prenatal exposures to ambient air pollution and to per- and polyfluoroalkyl substances are associated with adverse cardiometabolic health in mid-childhood and (2) explore the magnitude and impact of prenatal exposure to indoor air pollution in rural New England.
About Abby Fleisch
Abby Fleisch received her MD from Northwestern University Feinberg School of Medicine (2007). During medical school, she conducted research as a Clinical Research Training Program fellow, at the National Institutes of Health (2005-2006). She completed a residency in pediatrics (2010) and a fellowship in pediatric endocrinology (2013) at Boston Children’s Hospital. Additionally, she completed the Harvard-wide Pediatric Health Services Research Fellowship (2013) and received her MPH from Harvard School of Public Health (2013).