Overview

Dr. Rodrigue's research is aimed at understanding the biological underpinnings of psychiatric disorders, especially those related to psychosis, using structural and functional magnetic resonance imaging (MRI) and genetics. She primarily uses these tools for biomarker discovery, characterization, and validation. To accomplish this goal Dr. Rodrigue uses multiple imaging modalities and large scale datasets from both family-based and population-based cohorts. Current interests include genetic influences underlying brain based psychosis biomarkers and validation of existing neuroimaging biomarkers in psychosis using machine learning.

Background

Dr. Rodrigue completed her master's degree in Experimental Psychology from the University of Louisiana at Lafayette followed by a PhD in Psychology from the University of Georgia. She is currently a postdoc working under the supervision of Dr. David Glahn.

Researcher Services

Researcher Areas

  • Neuroimaging
  • Genetics
  • Psychosis

Research Departments

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Rodrigue AL, Knowles EE, Mollon J, Mathias SR, Koenis MM, Peralta JM, Leandro AC, Fox PT, Sprooten E, Kochunov P, Olvera RL, Duggirala R, Almasy L, Curran JE, Blangero J, Glahn DC. Evidence for genetic correlation between human cerebral white matter microstructure and inflammation. Hum Brain Mapp. 2019 Oct 01; 40(14):4180-4191. View abstract
  2. Knowles EEM, Curran JE, Göring HHH, Mathias SR, Mollon J, Rodrigue A, Olvera RL, Leandro A, Duggirala R, Almasy L, Blangero J, Glahn DC. Family-based analyses reveal novel genetic overlap between cytokine interleukin-8 and risk for suicide attempt. Brain Behav Immun. 2019 Aug; 80:292-299. View abstract
  3. Doucet GE, Moser DA, Rodrigue A, Bassett DS, Glahn DC, Frangou S. Person-Based Brain Morphometric Similarity is Heritable and Correlates With Biological Features. Cereb Cortex. 2019 Feb 01; 29(2):852-862. View abstract
  4. Mollon J, Mathias SR, Knowles EEM, Rodrigue A, Koenis MMG, Pearlson GD, Reichenberg A, Barrett J, Denbow D, Aberizk K, Zatony M, Poldrack RA, Blangero J, Glahn DC. Cognitive impairment from early to middle adulthood in patients with affective and nonaffective psychotic disorders. Psychol Med. 2019 Jan 04; 1-10. View abstract
  5. Burton CR, Schaeffer DJ, Bobilev AM, Pierce JE, Rodrigue AL, Krafft CE, Clementz BA, Lauderdale JD, McDowell JE. Microstructural differences in visual white matter tracts in people with aniridia. Neuroreport. 2018 12 05; 29(17):1473-1478. View abstract
  6. Knowles EEM, Mathias SR, Mollon J, Rodrigue A, Koenis MMG, Dyer TD, Goring HHH, Curran JE, Olvera RL, Duggirala R, Almasy L, Blangero J, Glahn DC. A QTL on chromosome 3q23 influences processing speed in humans. Genes Brain Behav. 2019 04; 18(4):e12530. View abstract
  7. Wang LY, Chung J, Park C, Choi H, Rodrigue AL, Pierce JE, Clementz BA, McDowell JE. Regularized aggregation of statistical parametric maps. Hum Brain Mapp. 2019 Jan; 40(1):65-79. View abstract
  8. Rodrigue AL, Schaeffer DJ, Pierce JE, Clementz BA, McDowell JE. Evaluating the Specificity of Cognitive Control Deficits in Schizophrenia Using Antisaccades, Functional Magnetic Resonance Imaging, and Healthy Individuals With Poor Cognitive Control. Front Psychiatry. 2018; 9:107. View abstract
  9. Rodrigue AL, McDowell JE, Tandon N, Keshavan MS, Tamminga CA, Pearlson GD, Sweeney JA, Gibbons RD, Clementz BA. Multivariate Relationships Between Cognition and Brain Anatomy Across the Psychosis Spectrum. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 12; 3(12):992-1002. View abstract
  10. Schaeffer DJ, Rodrigue AL, Burton CR, Pierce JE, Murphy MN, Clementz BA, McDowell JE. White matter fiber integrity of the saccadic eye movement network differs between schizophrenia and healthy groups. Psychophysiology. 2017 Dec; 54(12):1967-1977. View abstract
  11. Rodrigue AL, Austin BP, McDowell JE. Plasticity of prefrontal cortex connectivity in schizophrenia in response to antisaccade practice. Psychiatry Res Neuroimaging. 2017 Jul 30; 265:77-86. View abstract
  12. Schaeffer DJ, Rodrigue AL, Burton CR, Pierce JE, Unsworth N, Clementz BA, McDowell JE. White matter structural integrity differs between people with schizophrenia and healthy groups as a function of cognitive control. Schizophr Res. 2015 Dec; 169(1-3):62-68. View abstract
  13. Schwarz NF, Krafft CE, Chi L, Weinberger AL, Schaeffer DJ, Pierce JE, Rodrigue AL, Williams CF, DiBattisto CH, Maria BL, Davis CL, McDowell JE. Antisaccade-related brain activation in children with attention-deficit/hyperactivity disorder--A pilot study. Psychiatry Res. 2015 Nov 30; 234(2):272-9. View abstract
  14. Pierce JE, Krafft CE, Rodrigue AL, Bobilev AM, Lauderdale JD, McDowell JE. Increased functional connectivity in intrinsic neural networks in individuals with aniridia. Front Hum Neurosci. 2014; 8:1013. View abstract
  15. Schaeffer DJ, Krafft CE, Schwarz NF, Chi L, Rodrigue AL, Pierce JE, Allison JD, Yanasak NE, Liu T, Davis CL, McDowell JE. The relationship between uncinate fasciculus white matter integrity and verbal memory proficiency in children. Neuroreport. 2014 Aug 20; 25(12):921-5. View abstract
  16. Schaeffer DJ, Krafft CE, Schwarz NF, Chi L, Rodrigue AL, Pierce JE, Allison JD, Yanasak NE, Liu T, Davis CL, McDowell JE. An 8-month exercise intervention alters frontotemporal white matter integrity in overweight children. Psychophysiology. 2014 Aug; 51(8):728-33. View abstract
  17. Krafft CE, Schaeffer DJ, Schwarz NF, Chi L, Weinberger AL, Pierce JE, Rodrigue AL, Allison JD, Yanasak NE, Liu T, Davis CL, McDowell JE. Improved frontoparietal white matter integrity in overweight children is associated with attendance at an after-school exercise program. Dev Neurosci. 2014; 36(1):1-9. View abstract
  18. Krafft CE, Schwarz NF, Chi L, Weinberger AL, Schaeffer DJ, Pierce JE, Rodrigue AL, Yanasak NE, Miller PH, Tomporowski PD, Davis CL, McDowell JE. An 8-month randomized controlled exercise trial alters brain activation during cognitive tasks in overweight children. Obesity (Silver Spring). 2014 Jan; 22(1):232-42. View abstract