Research Overview

Dr. Olson's research focuses on examining parameters that effect the detection of disease outbreaks that are relatively small in size but characterized by spatial clustering. Detection algorithms are evaluated by inserting simulated clusters that vary on parameters of interest into historical data from hospital emergency departments.

About Karen Olson

Karen Olson received her PhD from Wayne State University. She completed post-doctoral work at the University of Geneva, Switzerland, and the University of Regensburg, Germany.

Key Publications

  • Olson KL, Bonetti M, Pagano M, Mandl KD. Real time spatial cluster detection using interpoint distances among precise patient locations. BMC Medical Informatics and Decision Making, 2005, 5:19.

  • Olson KL, Bonetti M, Pagano M, Mandl KD. A population- adjusted stable geospatial baseline for outbreak detection in syndromic surveillance. Morbidity and Mortality Weekly Report, Syndromic Surveillance Reports, 2004, 53:231.

  • Beitel AJ, Olson KL, Reis BY, Mandl KD. Use of emergency department chief complaint and diagnostic codes for identifying respiratory illness in a pediatric population. Pediatric Emergency Care, 2004, 20:355-360.

Researcher Services

Researcher Areas

  • Emergency Medicine

Research Departments

Research Divisions

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Lyons TW, Olson KL, Palmer NP, Horwitz R, Mandl KD, Fine AM. Patients Visiting Multiple Emergency Departments: Patterns, Costs, and Risk Factors. Acad Emerg Med. 2017 Nov; 24(11):1349-1357. View abstract
  2. Geva A, Olson KL, Liu C, Mandl KD. Provider Connectedness to Other Providers Reduces Risk of Readmission After Hospitalization for Heart Failure. Med Care Res Rev. 2017 Jul 01; 1077558717718626. View abstract
  3. Ong MS, Olson KL, Chadwick L, Liu C, Mandl KD. The Impact of Provider Networks on the Co-Prescriptions of Interacting Drugs: A Claims-Based Analysis. Drug Saf. 2017 03; 40(3):263-272. View abstract
  4. Bourgeois FT, Olson KL, Tse T, Ioannidis JP, Mandl KD. Prevalence and Characteristics of Interventional Trials Conducted Exclusively in Elderly Persons: A Cross-Sectional Analysis of Registered Clinical Trials. PLoS One. 2016; 11(5):e0155948. View abstract
  5. Ong MS, Olson KL, Cami A, Liu C, Tian F, Selvam N, Mandl KD. Erratum to: Provider patient-sharing networks and multiple-provider prescribing of benzodiazepines. J Gen Intern Med. 2016 May; 31(5):588. View abstract
  6. Lebowitz MB, Olson KL, Burns M, Harper MB, Bourgeois F. Drug-Drug Interactions Among Hospitalized Children Receiving Chronic Antiepileptic Drug Therapy. Hosp Pediatr. 2016 May; 6(5):282-9. View abstract
  7. Provenzi L, Olson KL, Montirosso R, Tronick E. Infants, mothers, and dyadic contributions to stability and prediction of social stress response at 6 months. Dev Psychol. 2016 Jan; 52(1):1-8. View abstract
  8. Bourgeois FT, Olson KL, Poduri A, Mandl KD. Comparison of Drug Utilization Patterns in Observational Data: Antiepileptic Drugs in Pediatric Patients. Paediatr Drugs. 2015 Oct; 17(5):401-10. View abstract
  9. Ong MS, Olson KL, Cami A, Liu C, Tian F, Selvam N, Mandl KD. Provider Patient-Sharing Networks and Multiple-Provider Prescribing of Benzodiazepines. J Gen Intern Med. 2016 Feb; 31(2):164-71. View abstract
  10. Mandl KD, Olson KL, Mines D, Liu C, Tian F. Provider collaboration: cohesion, constellations, and shared patients. J Gen Intern Med. 2014 Nov; 29(11):1499-505. View abstract
  11. Bourgeois FT, Olson KL, Ioannidis JP, Mandl KD. Association between pediatric clinical trials and global burden of disease. Pediatrics. 2014 Jan; 133(1):78-87. View abstract
  12. Bourgeois FT, Murthy S, Pinto C, Olson KL, Ioannidis JP, Mandl KD. Pediatric versus adult drug trials for conditions with high pediatric disease burden. Pediatrics. 2012 Aug; 130(2):285-92. View abstract
  13. Olson KL, Mandl KD. Temporal patterns of medications dispensed to children and adolescents in a national insured population. PLoS One. 2012; 7(7):e40991. View abstract
  14. Fink NS, Tronick E, Olson K, Lester B. Healthy newborns' neurobehavior: norms and relations to medical and demographic factors. J Pediatr. 2012 Dec; 161(6):1073-9. View abstract
  15. Reis BY, Olson KL, Tian L, Bohn RL, Brownstein JS, Park PJ, Cziraky MJ, Wilson MD, Mandl KD. A pharmacoepidemiological network model for drug safety surveillance: statins and rhabdomyolysis. Drug Saf. 2012 May 01; 35(5):395-406. View abstract
  16. Fine AM, Brownstein JS, Nigrovic LE, Kimia AA, Olson KL, Thompson AD, Mandl KD. Integrating spatial epidemiology into a decision model for evaluation of facial palsy in children. Arch Pediatr Adolesc Med. 2011 Jan; 165(1):61-7. View abstract
  17. Bourgeois FC, Olson KL, Mandl KD. Patients treated at multiple acute health care facilities: quantifying information fragmentation. Arch Intern Med. 2010 Dec 13; 170(22):1989-95. View abstract
  18. Lee LK, Fleegler EW, Forbes PW, Olson KL, Mooney DP. The modern paediatric injury pyramid: injuries in Massachusetts children and adolescents. Inj Prev. 2010 Apr; 16(2):123-6. View abstract
  19. Fine AM, Reis BY, Nigrovic LE, Goldmann DA, Laporte TN, Olson KL, Mandl KD. Use of population health data to refine diagnostic decision-making for pertussis. J Am Med Inform Assoc. 2010 Jan-Feb; 17(1):85-90. View abstract
  20. Weinberg MK, Beeghly M, Olson KL, Tronick E. EFFECTS OF MATERNAL DEPRESSION AND PANIC DISORDER ON MOTHER-INFANT INTERACTIVE BEHAVIOR IN THE FACE-TO-FACE STILL-FACE PARADIGM. Infant Ment Health J. 2008 Sep; 29(5):472-491. View abstract
  21. Bourgeois FT, Simons WW, Olson K, Brownstein JS, Mandl KD. Evaluation of influenza prevention in the workplace using a personally controlled health record: randomized controlled trial. J Med Internet Res. 2008 Mar 14; 10(1):e5. View abstract
  22. Weinberg MK, Beeghly M, Olson KL, Tronick E. A Still-face Paradigm for Young Children: 2½ Year-olds' Reactions to Maternal Unavailability during the Still-face. J Dev Process. 2008; 3(1):4-22. View abstract
  23. Bourgeois F, Olson K, Mandl KD. Patients treated across multiple sites of care: a case for personally controlled health records. AMIA Annu Symp Proc. 2007 Oct 11; 881. View abstract
  24. Reis BY, Kirby C, Hadden LE, Olson K, McMurry AJ, Daniel JB, Mandl KD. AEGIS: a robust and scalable real-time public health surveillance system. J Am Med Inform Assoc. 2007 Sep-Oct; 14(5):581-8. View abstract
  25. Olson KL, Grannis SJ, Mandl KD. Privacy protection versus cluster detection in spatial epidemiology. Am J Public Health. 2006 Nov; 96(11):2002-8. View abstract
  26. Weinberg MK, Olson KL, Beeghly M, Tronick EZ. Making up is hard to do, especially for mothers with high levels of depressive symptoms and their infant sons. J Child Psychol Psychiatry. 2006 Jul; 47(7):670-83. View abstract
  27. Kimia A, Brownstein JS, Olson KL, Zak V, Bourgeois FT, Mandl KD. Lumbar puncture ordering and results in the pediatric population: a promising data source for surveillance systems. Acad Emerg Med. 2006 Jul; 13(7):767-73. View abstract
  28. Bourgeois FT, Olson KL, Brownstein JS, McAdam AJ, Mandl KD. Validation of syndromic surveillance for respiratory infections. Ann Emerg Med. 2006 Mar; 47(3):265.e1. View abstract
  29. Cassa CA, Iancu K, Olson KL, Mandl KD. A software tool for creating simulated outbreaks to benchmark surveillance systems. BMC Med Inform Decis Mak. 2005 Jul 14; 5:22. View abstract
  30. Olson KL, Bonetti M, Pagano M, Mandl KD. Real time spatial cluster detection using interpoint distances among precise patient locations. BMC Med Inform Decis Mak. 2005 Jun 21; 5:19. View abstract
  31. Beitel AJ, Olson KL, Reis BY, Mandl KD. Use of emergency department chief complaint and diagnostic codes for identifying respiratory illness in a pediatric population. Pediatr Emerg Care. 2004 Jun; 20(6):355-60. View abstract
  32. Tronick EZ, Fetters L, Olson KL, Chen Y. Similar and functionally typical kinematic reaching parameters in 7- and 15-month-old in utero cocaine-exposed and unexposed infants. Dev Psychobiol. 2004 Apr; 44(3):168-75. View abstract
  33. Tronick EZ, Olson K, Rosenberg R, Bohne L, Lu J, Lester BM. Normative neurobehavioral performance of healthy infants on the Neonatal Intensive Care Unit Network Neurobehavioral Scale. Pediatrics. 2004 Mar; 113(3 Pt 2):676-8. View abstract
  34. Beeghly M, Olson KL, Weinberg MK, Pierre SC, Downey N, Tronick EZ. Prevalence, stability, and socio-demographic correlates of depressive symptoms in Black mothers during the first 18 months postpartum. Matern Child Health J. 2003 Sep; 7(3):157-68. View abstract
  35. Beeghly M, Weinberg MK, Olson KL, Kernan H, Riley J, Tronick EZ. Stability and change in level of maternal depressive symptomatology during the first postpartum year. J Affect Disord. 2002 Sep; 71(1-3):169-80. View abstract
  36. Weinberg MK, Tronick EZ, Beeghly M, Olson KL, Kernan H, Riley JM. Subsyndromal depressive symptoms and major depression in postpartum women. Am J Orthopsychiatry. 2001 Jan; 71(1):87-97. View abstract
  37. Weinberg MK, Tronick EZ, Cohn JF, Olson KL. Gender differences in emotional expressivity and self-regulation during early infancy. Dev Psychol. 1999 Jan; 35(1):175-88. View abstract
  38. Poland ML, Ager JW, Olson KL, Sokol RJ. Quality of prenatal care; selected social, behavioral, and biomedical factors; and birth weight. Obstet Gynecol. 1990 Apr; 75(4):607-12. View abstract
  39. Berman RF, Lee JA, Olson KL, Goldman MS. Effects of naloxone on ethanol dependence in rats. Drug Alcohol Depend. 1984 May; 13(3):245-54. View abstract