Research Overview

Dr. McBride’s research focuses on clinical effectiveness and systems-based approaches to patient safety and quality in caring for hospitalized children. Her most recent projects have aimed to develop best clinical practices for children hospitalized with high-risk pediatric conditions such as asthma, bronchiolitis and osteomyelitis. She receives both federal and private funding for her research. Her present work includes a federally funded, multi-centered study aimed at augmenting a national pediatric database (Pediatric Health Information System- PHIS) with real-time clinical data to improve the reliability of future clinical research. She currently leads a comparative effectiveness study using this augmented database to compare treatment failure rates for osteomyelitis in the era of increased community-acquired methicillin-resistant staph aureus (MRSA). In addition, she is part of a leadership team conducting a privately funded national stakeholder project to develop national consensus guidelines for pediatric hospital discharge planning.

About Sarah McBride

Dr. McBride is an Instructor in Pediatrics at Harvard Medical School.  She completed her pediatric residency training at The Children’s Hospital of Philadelphia and a Fellowship in Hospital Medicine at Boston Children’s Hospital including the Program for Clinical Effectiveness at Harvard School of Public Health. She is a Director of Resident Education for Inpatient Medicine and attends on the inpatient pediatric wards at Boston Children’s Hospital while supervising Boston Combined Residency Program pediatric residents and Harvard medical students. She is a member of the teaching faculty for other resident curriculum courses.  Dr. McBride is also involved in a number of hospital-wide committees related to safety and quality initiatives.

Active Projects

2010-2014 PHIS +: Comparative Effectiveness of Empiric Antibiotic Choices for Treatment of Osteomyelitis in the era of MRSA

Agency for Health Care Research and Quality (AHRQ), R01 HS019862-01
Principal Investigator

This study uses the augmented Pediatric Health Information System (PHIS) database to compare treatment failure rates among those patients hospitalized with osteomyelitis who are treated empirically with MRSA-covering antibiotics to those patients who do not receive initial antibiotics to cover MRSA.

Researcher Services

Researcher Areas

  • Quality of Care
  • Patient Safety
  • Asthma

Research Departments

Research Divisions


Publications powered by Harvard Catalyst Profiles

  1. McBride S, Thurm C, Gouripeddi R, Stone B, Jaggard P, Shah SS, Tieder JS, Butcher R, Weiser J, Hall M, Keren R, Landrigan CP. Comparison of Empiric Antibiotics for Acute Osteomyelitis in Children. Hosp Pediatr. 2018 May; 8(5):280-287. View abstract
  2. Wells S, O'Neill M, Rogers J, Blaine K, Hoffman A, McBride S, Tschudy MM, Shumskiy I, Mauskar S, Berry JG. Nursing-led Home Visits Post-hospitalization for Children with Medical Complexity. J Pediatr Nurs. 2017 May - Jun; 34:10-16. View abstract
  3. Berry JG, Blaine K, Rogers J, McBride S, Schor E, Birmingham J, Schuster MA, Feudtner C. A framework of pediatric hospital discharge care informed by legislation, research, and practice. JAMA Pediatr. 2014 Oct; 168(10):955-62; quiz 965-6. View abstract
  4. Caplow J, McBride SC, Steil GM, Wong J. Changes in cardiac output and stroke volume as measured by non-invasive CO monitoring in infants with RSV bronchiolitis. J Clin Monit Comput. 2012 Jun; 26(3):197-205. View abstract
  5. McBride SC. Management of parapneumonic effusions in pediatrics: current practice. J Hosp Med. 2008 May; 3(3):263-70. View abstract
  6. McBride SC, Chiang VW, Goldmann DA, Landrigan CP. Preventable adverse events in infants hospitalized with bronchiolitis. Pediatrics. 2005 Sep; 116(3):603-8. View abstract
  7. McBride SC. Office laboratory procedures, office economics, parenting and parent education, and urinary tract infection. Curr Opin Pediatr. 2003 Dec; 15(6):641-9. View abstract