Research Overview

Dr. Landrigan is Research Director of Inpatient Pediatrics at Boston Children’s Hospital and a practicing pediatric hospitalist. He seeks to study and improve the safety and quality of care for hospitalized children. Over the past decade, he has served as the principal investigator of a series of cohort studies, randomized controlled trials, and multi-center intervention projects that have evaluated the effectiveness of novel interventions designed to improve patient safety.  He has strong interests in the effects of physicians' sleep deprivation, work schedules, teamwork, and handoffs of care.  He was the first Chair, and is a current Executive Council Member of the Pediatric Research in Inpatient Settings (PRIS) Network, the only federally funded hospitalist research network in the U.S.

Major goals of Dr. Landrigan's work include:

  • To develop rigorous systems for studying the quality and safety of hospital care
  • To develop innovative approaches to the organization of inpatient care, such as interventions designed to improve physicians' working conditions, teamwork, and handoffs
  • To carefully evaluate the effectiveness of interventions designed to improve care, and to continuously improve these interventions to achieve optimal safety and health
  • To broadly disseminate effective innovations through education and health policy efforts

About Christopher Landrigan, MD, MPH

Dr. Landrigan received his BA from Haverford College, his MD from Mount Sinai School of Medicine and his MPH from the Harvard School of Public Health. He completed his pediatrics residency and a fellowship in hospital medicine / health services research at Boston Children's Hospital, as well as a health policy fellowship at the U.S. Department of Health and Human Services. He has received numerous research and teaching awards including Boston Children’s Hospital’s Janeway Award for Excellence in Clinical Teaching, the Sleep Research Society’s Young Investigator Award, the Society of Hospital Medicine’s Excellence in Research Award, and Academy Health’s Nemours Child Health Services Research Award.  He is an elected member of the Society for Pediatric Research, the American Society for Clinical Investigation, and the American Pediatric Society.

Key Publications

  • Landrigan CP, Rothschild JM, Cronin JW, Kaushal R, Burdick E, Katz JT, Lilly CM, Stone PH, Lockley SW, Bates DW, Czeisler CA. Effect of reducing interns' work hours on serious medical errors in intensive care units. New Engl J Med. 2004;351(18):1838-1848.
  • Rothschild JM, Landrigan CP, Cronin JW, Kaushal R, Lockley SE, Burdick E, Stone PH, Lilly CM, Katz JT, Czeisler CA, Bates DW. The Critical Care Safety Study: the incidence and nature of adverse events and near-misses in intensive care. Crit Care Med. 2005;33(8):1694-1700.
  • Walsh KE, Adams WG, Bauchner H, Vinci RJ, Chessare JB, Cooper MR, Hebert PM, Schainker EG, Landrigan CP. Medication errors related to computerized order entry for children. Pediatrics. 2006;118(5):1872-1879.
  • Landrigan CP, Barger LK, Cade BE, Ayas NT, Czeisler CA. Interns’ compliance with Accreditation Council for Graduate Medical Education work-hour limits.  JAMA. 2006;296(9):1063-1070.
  • Fahrenkopf AM, Sectish TC, Barger LK, Sharek PJ, Lewin D, Chiang VW, Edwards S, Wiedermann BL, Landrigan CP. Rates of medication errors among depressed and burned out Residents: A prospective cohort study.  BMJ. 2008;336(7642):488-491. PMCID: PMC2258399.
  • Landrigan CP, Fahrenkopf AM, Lewin D, Sharek PJ, Barger LK, Eisner M, Edwards S, Chiang VW, Wiedermann BL, Sectish TC. Effects of the Accreditation Council for Graduate Medical Education duty hour limits on sleep, work hours, and safety.  Pediatrics. 2008;122(2):250-258.
  • Rothschild JM, Keohane CA, Rogers S, Gardner R, Lipsitz SR, Salzberg CA, Yu T, Yoon CS, Williams DH, Wien MF, Czeisler CA, Bates DW, Landrigan CP. Risks of complications by attending physicians after performing nighttime procedures.  JAMA. 2009;302(14):1565-1572.
  • Starmer AJ, Sectish TC, Simon DW, Keohane C, McSweeney ME, Chung EY, Yoon CS, Lipsitz SR, Wassner AJ, Harper MB, Landrigan CP.  Rates of medical errors and preventable adverse events among hospitalized children following implementation of a resident handoff bundle. JAMA. 2013;310(21):2262-2270.
  • Landrigan CP, Parry G, Bones CB, Hackbarth AD, Goldmann DA, Sharek PJ. Temporal trends in rates of patient harm due to medical care. New Engl J Med. 2010;363(22):2124-2134.
  • Sharek PJ, Parry G, Goldmann DA, Bones CB, Hackbarth AD, Rhoda D, Murphy C, Landrigan CP. Performance characteristics of a methodology to quantify adverse events over time in hospitalized patients.  Health Serv Res 2011; 46:654-678. PMCID: PMC3064924

Active Projects

2012-2017 Multi-Center Trial of Limiting PGY2&3 Resident Work Hours on Patient Safety

NHLBI U01 HL111478
Principal Investigator

In the ROSTERS (Randomized Order Safety Trial Evaluating Resident Schedules) project, we are working with the Sleep Research Network to conduct a six-center randomized controlled crossover trial evaluating the effect on patient safety, resident safety, and resident education of eliminating shifts >16 hours for 2nd and 3rd year pediatric residents in pediatric intensive care units.

2013-2014 The I-PASS Electronic Family Sign out:  A Technological Innovation to Empower and Engage Families of Hospitalized Patients

Web Site: I-PASS Study

Taking on Tomorrow Innovation Program, Boston Children’s Hospital
Principal Investigator

In this study, we are developing a computerized handoff tool for families, to facilitate provider-family communication during hospitalization.

2014-2017 Bringing I-PASS to the Bedside:  a Communication Bundle to Improve Patient Safety and Experience

Web Site: I-PASS Study

Patient Centered Outcomes Research Institute (PCORI) R-CDR-1306-03556
Principal Investigator

In this 10-center study that builds on the I-PASS Study, we are testing the effects on patient safety, care processes, and workflow of adapting and integrating I-PASS communication tools and strategies into family centered rounds and other family communications throughout the day. The manner in which adoption across sites is affected by patient and hospital-level variables will be assessed.

Researcher Services

Researcher Areas

  • Patient Safety
  • Resident Sleep Loss

Research Departments

Research Divisions

Researcher Labs

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. McBride S, Thurm C, Gouripeddi R, Stone B, Jaggard P, Shah SS, Tieder JS, Butcher R, Weiser J, Hall M, Keren R, Landrigan CP. Comparison of Empiric Antibiotics for Acute Osteomyelitis in Children. Hosp Pediatr. 2018 May; 8(5):280-287. View abstract
  2. Winn AS, Marcus CH, Sectish TC, Williams K, Landrigan CP. A Comparison of Resident Self-Perception and Pediatric Hospitalist Perceptions of the Supervisory Needs of New Interns. Hosp Pediatr. 2018 Apr; 8(4):214-219. View abstract
  3. Simpkin AL, Khan A, West DC, Garcia BM, Sectish TC, Spector ND, Landrigan CP. Stress From Uncertainty and Resilience Among Depressed and Burned Out Residents: A Cross-Sectional Study. Acad Pediatr. 2018 Mar 07. View abstract
  4. Khan A, Cray S, Mercer AN, Ramotar MW, Landrigan CP. Engaging Families as True Partners During Hospitalization. J Hosp Med. 2018 05 01; 13(5):358-360. View abstract
  5. Winn AS, Marcus CH, Williams K, Smith GC, Gorbounova I, Sectish TC, Landrigan CP. Development, Implementation, and Assessment of the Intensive Clinical Orientation for Residents (ICOR) Curriculum: A Pilot Intervention to Improve Intern Clinical Preparedness. Acad Pediatr. 2018 Mar; 18(2):140-144. View abstract
  6. Khan A, Furtak SL, Melvin P, Rogers JE, Schuster MA, Landrigan CP. Parent-Provider Miscommunications in Hospitalized Children. Hosp Pediatr. 2017 Sep; 7(9):505-515. View abstract
  7. Starmer AJ, Schnock KO, Lyons A, Hehn RS, Graham DA, Keohane C, Landrigan CP. Effects of the I-PASS Nursing Handoff Bundle on communication quality and workflow. BMJ Qual Saf. 2017 Dec; 26(12):949-957. View abstract
  8. Geva A, Landrigan CP, van der Velden MG, Randolph AG. Simulation of a Novel Schedule for Intensivist Staffing to Improve Continuity of Patient Care and Reduce Physician Burnout. Crit Care Med. 2017 Jul; 45(7):1138-1144. View abstract
  9. Coffey M, Thomson K, Li SA, Bismilla Z, Starmer AJ, O'Toole JK, Blankenburg RL, Rosenbluth G, Cole FS, Yu CE, Hepps JH, Sectish TC, Spector ND, Srivastava R, Allen AD, Mahant S, Landrigan CP. Resident Experiences With Implementation of the I-PASS Handoff Bundle. J Grad Med Educ. 2017 Jun; 9(3):313-320. View abstract
  10. Starmer AJ, Spector ND, West DC, Srivastava R, Sectish TC, Landrigan CP. Integrating Research, Quality Improvement, and Medical Education for Better Handoffs and Safer Care: Disseminating, Adapting, and Implementing the I-PASS Program. Jt Comm J Qual Patient Saf. 2017 Jul; 43(7):319-329. View abstract
  11. Destino LA, Valentine M, Sheikhi FH, Starmer AJ, Landrigan CP, Sanders L. Inpatient Hospital Factors and Resident Time With Patients and Families. Pediatrics. 2017 May; 139(5). View abstract
  12. Khan A, Coffey M, Litterer KP, Baird JD, Furtak SL, Garcia BM, Ashland MA, Calaman S, Kuzma NC, O'Toole JK, Patel A, Rosenbluth G, Destino LA, Everhart JL, Good BP, Hepps JH, Dalal AK, Lipsitz SR, Yoon CS, Zigmont KR, Srivastava R, Starmer AJ, Sectish TC, Spector ND, West DC, Landrigan CP, Allair BK, Alminde C, Alvarado-Little W, Atsatt M, Aylor ME, Bale JF, Balmer D, Barton KT, Beck C, Bismilla Z, Blankenburg RL, Chandler D, Choudhary A, Christensen E, Coghlan-McDonald S, Cole FS, Corless E, Cray S, Da Silva R, Dahale D, Dreyer B, Growdon AS, Gubler L, Guiot A, Harris R, Haskell H, Kocolas I, Kruvand E, Lane MM, Langrish K, Ledford CJW, Lewis K, Lopreiato JO, Maloney CG, Mangan A, Markle P, Mendoza F, Micalizzi DA, Mittal V, Obermeyer M, O'Donnell KA, Ottolini M, Patel SJ, Pickler R, Rogers JE, Sanders LM, Sauder K, Shah SS, Sharma M, Simpkin A, Subramony A, Thompson ED, Trueman L, Trujillo T, Turmelle MP, Warnick C, Welch C, White AJ, Wien MF, Winn AS, Wintch S, Wolf M, Yin HS, Yu CE. Families as Partners in Hospital Error and Adverse Event Surveillance. JAMA Pediatr. 2017 Apr 01; 171(4):372-381. View abstract
  13. Khan A, Baird J, Rogers JE, Furtak SL, Williams KA, Allair B, Litterer KP, Sharma M, Smith A, Schuster MA, Landrigan CP. Parent and Provider Experience and Shared Understanding After a Family-Centered Nighttime Communication Intervention. Acad Pediatr. 2017 May - Jun; 17(4):389-402. View abstract
  14. Klerman EB, Beckett SA, Landrigan CP. Applying mathematical models to predict resident physician performance and alertness on traditional and novel work schedules. BMC Med Educ. 2016 Sep 13; 16(1):239. View abstract
  15. Landrigan CP, Stockwell D, Toomey SL, Loren S, Tracy M, Jang J, Quinn JA, Ashrafzadeh S, Wang M, Sharek PJ, Parry G, Schuster MA. Performance of the Global Assessment of Pediatric Patient Safety (GAPPS) Tool. Pediatrics. 2016 Jun; 137(6). View abstract
  16. Khan A, Rogers JE, Forster CS, Furtak SL, Schuster MA, Landrigan CP. Communication and Shared Understanding Between Parents and Resident-Physicians at Night. Hosp Pediatr. 2016 Jun; 6(6):319-29. View abstract
  17. Feraco AM, Starmer AJ, Sectish TC, Spector ND, West DC, Landrigan CP. Reliability of Verbal Handoff Assessment and Handoff Quality Before and After Implementation of a Resident Handoff Bundle. Acad Pediatr. 2016 08; 16(6):524-31. View abstract
  18. Khan A, Furtak SL, Melvin P, Rogers JE, Schuster MA, Landrigan CP. Parent-Reported Errors and Adverse Events in Hospitalized Children. JAMA Pediatr. 2016 Apr; 170(4):e154608. View abstract
  19. Calaman S, Hepps JH, Bismilla Z, Carraccio C, Englander R, Feraco A, Landrigan CP, Lopreiato JO, Sectish TC, Starmer AJ, Yu CE, Spector ND, West DC. The Creation of Standard-Setting Videos to Support Faculty Observations of Learner Performance and Entrustment Decisions. Acad Med. 2016 Feb; 91(2):204-9. View abstract
  20. Schondelmeyer AC, Brady PW, Landrigan CP. Alarm fatigue: Clearing the air. J Hosp Med. 2016 Feb; 11(2):153-4. View abstract
  21. Starmer AJ, Destino L, Yoon CS, Landrigan CP. Intern and Resident Workflow Patterns on Pediatric Inpatient Units: A Multicenter Time-Motion Study. JAMA Pediatr. 2015 Dec; 169(12):1175-7. View abstract
  22. Khan A, Rogers JE, Melvin P, Furtak SL, Faboyede GM, Schuster MA, Landrigan CP. Physician and Nurse Nighttime Communication and Parents' Hospital Experience. Pediatrics. 2015 Nov; 136(5):e1249-58. View abstract
  23. Rosenbluth G, Landrigan CP. The authors reply "Variation in printed handoff documents: Results and recommendations from a multicenter needs assessment". J Hosp Med. 2016 Jan; 11(1):81-2. View abstract
  24. Rajaratnam SM, Landrigan CP, Czeisler CA. Graduated Driver-Licensing: The Authors Reply. Health Aff (Millwood). 2015 Sep; 34(9):1610. View abstract
  25. Rajaratnam SM, Landrigan CP, Wang W, Kaprielian R, Moore RT, Czeisler CA. Teen Crashes Declined After Massachusetts Raised Penalties For Graduated Licensing Law Restricting Night Driving. Health Aff (Millwood). 2015 Jun; 34(6):963-70. View abstract
  26. Rosenbluth G, Bale JF, Starmer AJ, Spector ND, Srivastava R, West DC, Sectish TC, Landrigan CP. Variation in printed handoff documents: Results and recommendations from a multicenter needs assessment. J Hosp Med. 2015 Aug; 10(8):517-24. View abstract
  27. Stockwell DC, Bisarya H, Classen DC, Kirkendall ES, Landrigan CP, Lemon V, Tham E, Hyman D, Lehman SM, Searles E, Hall M, Muething SE, Schuster MA, Sharek PJ. A trigger tool to detect harm in pediatric inpatient settings. Pediatrics. 2015 Jun; 135(6):1036-42. View abstract
  28. Landrigan CP. Crying wolf: False alarms and patient safety. J Hosp Med. 2015 Jun; 10(6):409-10. View abstract
  29. Starmer AJ, Landrigan CP. Changes in medical errors with a handoff program. N Engl J Med. 2015 01 29; 372(5):490-1. View abstract
  30. Starmer AJ, Spector ND, Srivastava R, West DC, Rosenbluth G, Allen AD, Noble EL, Tse LL, Dalal AK, Keohane CA, Lipsitz SR, Rothschild JM, Wien MF, Yoon CS, Zigmont KR, Wilson KM, O'Toole JK, Solan LG, Aylor M, Bismilla Z, Coffey M, Mahant S, Blankenburg RL, Destino LA, Everhart JL, Patel SJ, Bale JF, Spackman JB, Stevenson AT, Calaman S, Cole FS, Balmer DF, Hepps JH, Lopreiato JO, Yu CE, Sectish TC, Landrigan CP. Changes in medical errors after implementation of a handoff program. N Engl J Med. 2014 Nov 06; 371(19):1803-12. View abstract
  31. Bigham MT, Logsdon TR, Manicone PE, Landrigan CP, Hayes LW, Randall KH, Grover P, Collins SB, Ramirez DE, O'Guin CD, Williams CI, Warnick RJ, Sharek PJ. Decreasing handoff-related care failures in children's hospitals. Pediatrics. 2014 Aug; 134(2):e572-9. View abstract
  32. Starmer AJ, O'Toole JK, Rosenbluth G, Calaman S, Balmer D, West DC, Bale JF, Yu CE, Noble EL, Tse LL, Srivastava R, Landrigan CP, Sectish TC, Spector ND. Development, implementation, and dissemination of the I-PASS handoff curriculum: A multisite educational intervention to improve patient handoffs. Acad Med. 2014 Jun; 89(6):876-84. View abstract
  33. Walsh KE, Bundy DG, Landrigan CP. Preventing health care-associated harm in children. JAMA. 2014 May 07; 311(17):1731-2. View abstract
  34. O'Toole JK, West DC, Starmer AJ, Yu CE, Calaman S, Rosenbluth G, Hepps JH, Lopreiato JO, Landrigan CP, Sectish TC, Spector ND. Placing faculty development front and center in a multisite educational initiative: lessons from the I-PASS Handoff study. Acad Pediatr. 2014 May-Jun; 14(3):221-4. View abstract
  35. Kevat DA, Cameron PA, Davies AR, Landrigan CP, Rajaratnam SW. Safer hours for doctors and improved safety for patients. Med J Aust. 2014 Apr 21; 200(7):396-8. View abstract
  36. Starmer AJ, Sectish TC, Simon DW, Keohane C, McSweeney ME, Chung EY, Yoon CS, Lipsitz SR, Wassner AJ, Harper MB, Landrigan CP. Rates of medical errors and preventable adverse events among hospitalized children following implementation of a resident handoff bundle. JAMA. 2013 Dec 04; 310(21):2262-70. View abstract
  37. Simon TD, Starmer AJ, Conway PH, Landrigan CP, Shah SS, Shen MW, Sectish TC, Spector ND, Tieder JS, Srivastava R, Willis LE, Wilson KM. Quality improvement research in pediatric hospital medicine and the role of the Pediatric Research in Inpatient Settings (PRIS) network. Acad Pediatr. 2013 Nov-Dec; 13(6 Suppl):S54-60. View abstract
  38. O'Toole JK, Stevenson AT, Good BP, Guiot AB, Solan LG, Tse LL, Landrigan CP, Sectish TC, Srivastava R, Starmer AJ, Spector ND. Closing the gap: a needs assessment of medical students and handoff training. J Pediatr. 2013 May; 162(5):887-8.e1. View abstract
  39. Landrigan CP. New questions on the road to safer health care. Pediatrics. 2013 May; 131(5):e1621-2. View abstract
  40. McSweeney ME, Landrigan CP, Jiang H, Starmer A, Lightdale JR. Answering questions on call: pediatric resident physicians' use of handoffs and other resources. J Hosp Med. 2013 Jun; 8(6):328-33. View abstract
  41. McCormick F, Kadzielski J, Evans BT, Landrigan CP, Herndon J, Rubash H. Fatigue optimization scheduling in graduate medical education: reducing fatigue and improving patient safety. J Grad Med Educ. 2013 Mar; 5(1):107-11. View abstract
  42. Cohen IG, Czeisler CA, Landrigan CP. Making residency work hour rules work. J Law Med Ethics. 2013; 41(1):310-4. View abstract
  43. Hayes SM, Murray S, Castriotta RJ, Landrigan CP, Malhotra A. (Mis) perceptions and interactions of sleep specialists and generalists: obstacles to referrals to sleep specialists and the multidisciplinary team management of sleep disorders. J Clin Sleep Med. 2012 Dec 15; 8(6):633-42. View abstract
  44. Rosenbluth G, Landrigan CP. Sleep science, schedules, and safety in hospitals: challenges and solutions for pediatric providers. Pediatr Clin North Am. 2012 Dec; 59(6):1317-28. View abstract
  45. Srivastava R, Landrigan CP. Development of the Pediatric Research in Inpatient Settings (PRIS) Network: lessons learned. J Hosp Med. 2012 Oct; 7(8):661-4. View abstract
  46. Landrigan CP, Srivastava R. Pediatric hospitalists: coming of age in 2012. Arch Pediatr Adolesc Med. 2012 Aug; 166(8):696-9. View abstract
  47. Gordon MB, Sectish TC, Elliott MN, Klein D, Landrigan CP, Bogart LM, Amrock S, Burke A, Chiang VW, Schuster MA. Pediatric residents' perspectives on reducing work hours and lengthening residency: a national survey. Pediatrics. 2012 Jul; 130(1):99-107. View abstract
  48. Auger KA, Landrigan CP, Gonzalez del Rey JA, Sieplinga KR, Sucharew HJ, Simmons JM. Better rested, but more stressed? Evidence of the effects of resident work hour restrictions. Acad Pediatr. 2012 Jul-Aug; 12(4):335-43. View abstract
  49. McCormick F, Kadzielski J, Landrigan CP, Evans B, Herndon JH, Rubash HE. Surgeon fatigue: a prospective analysis of the incidence, risk, and intervals of predicted fatigue-related impairment in residents. Arch Surg. 2012 May; 147(5):430-5. View abstract
  50. Starmer AJ, Spector ND, Srivastava R, Allen AD, Landrigan CP, Sectish TC. I-pass, a mnemonic to standardize verbal handoffs. Pediatrics. 2012 Feb; 129(2):201-4. View abstract
  51. Rajaratnam SM, Barger LK, Lockley SW, Shea SA, Wang W, Landrigan CP, O'Brien CS, Qadri S, Sullivan JP, Cade BE, Epstein LJ, White DP, Czeisler CA. Sleep disorders, health, and safety in police officers. JAMA. 2011 Dec 21; 306(23):2567-78. View abstract
  52. Chua KP, Gordon MB, Sectish T, Landrigan CP. Effects of a night-team system on resident sleep and work hours. Pediatrics. 2011 Dec; 128(6):1142-7. View abstract
  53. Landrigan CP. Healthcare provider working conditions and well-being: sharing international lessons to improve patient safety. J Pediatr (Rio J). 2011 Nov-Dec; 87(6):463-5. View abstract
  54. Majekodunmi A, Landrigan CP. The effect of physician sleep deprivation on patient safety in perinatal-neonatal medicine. Am J Perinatol. 2012 Jan; 29(1):43-8. View abstract
  55. Blum AB, Shea S, Czeisler CA, Landrigan CP, Leape L. Implementing the 2009 Institute of Medicine recommendations on resident physician work hours, supervision, and safety. Nat Sci Sleep. 2011; 3:47-85. View abstract
  56. Gordon MB, Melvin P, Graham D, Fifer E, Chiang VW, Sectish TC, Landrigan CP. Unit-based care teams and the frequency and quality of physician-nurse communications. Arch Pediatr Adolesc Med. 2011 May; 165(5):424-8. View abstract
  57. Landrigan CP, Parry GJ, Bones CB, Hackbarth AD, Goldmann DA, Sharek PJ. Temporal trends in rates of patient harm resulting from medical care. N Engl J Med. 2010 Nov 25; 363(22):2124-34. View abstract
  58. Gordon JA, Alexander EK, Lockley SW, Flynn-Evans E, Venkatan SK, Landrigan CP, Czeisler CA. Does simulator-based clinical performance correlate with actual hospital behavior? The effect of extended work hours on patient care provided by medical interns. Acad Med. 2010 Oct; 85(10):1583-8. View abstract
  59. Sectish TC, Starmer AJ, Landrigan CP, Spector ND. Establishing a multisite education and research project requires leadership, expertise, collaboration, and an important aim. Pediatrics. 2010 Oct; 126(4):619-22. View abstract
  60. Sharek PJ, Parry G, Goldmann D, Bones K, Hackbarth A, Resar R, Griffin FA, Rhoda D, Murphy C, Landrigan CP. Performance characteristics of a methodology to quantify adverse events over time in hospitalized patients. Health Serv Res. 2011 Apr; 46(2):654-78. View abstract
  61. Levine AC, Adusumilli J, Landrigan CP. Effects of reducing or eliminating resident work shifts over 16 hours: a systematic review. Sleep. 2010 08; 33(8):1043-53. View abstract
  62. Mittal VS, Sigrest T, Ottolini MC, Rauch D, Lin H, Kit B, Landrigan CP, Flores G. Family-centered rounds on pediatric wards: a PRIS network survey of US and Canadian hospitalists. Pediatrics. 2010 Jul; 126(1):37-43. View abstract
  63. Blum AB, Raiszadeh F, Shea S, Mermin D, Lurie P, Landrigan CP, Czeisler CA. US public opinion regarding proposed limits on resident physician work hours. BMC Med. 2010 Jun 01; 8:33. View abstract
  64. Landrigan CP. Resident sleep deprivation and critical care: the unintended consequences of inaction. Crit Care Med. 2010 Mar; 38(3):980-1. View abstract
  65. Rothschild JM, Keohane CA, Rogers S, Gardner R, Lipsitz SR, Salzberg CA, Yu T, Yoon CS, Williams DH, Wien MF, Czeisler CA, Bates DW, Landrigan CP. Risks of complications by attending physicians after performing nighttime procedures. JAMA. 2009 Oct 14; 302(14):1565-72. View abstract
  66. Gaies MG, Morris SA, Hafler JP, Graham DA, Capraro AJ, Zhou J, Landrigan CP, Sandora TJ. Reforming procedural skills training for pediatric residents: a randomized, interventional trial. Pediatrics. 2009 Aug; 124(2):610-9. View abstract
  67. Cappuccio FP, Lockley SW, Landrigan CP. Cappuccio response to correspondence. QJM. 2009 May; 102(5):363-4. View abstract
  68. Barger LK, Lockley SW, Rajaratnam SM, Landrigan CP. Neurobehavioral, health, and safety consequences associated with shift work in safety-sensitive professions. Curr Neurol Neurosci Rep. 2009 Mar; 9(2):155-64. View abstract
  69. Cappuccio FP, Bakewell A, Taggart FM, Ward G, Ji C, Sullivan JP, Edmunds M, Pounder R, Landrigan CP, Lockley SW, Peile E. Implementing a 48 h EWTD-compliant rota for junior doctors in the UK does not compromise patients' safety: assessor-blind pilot comparison. QJM. 2009 Apr; 102(4):271-82. View abstract
  70. Landrigan CP. Driving drowsy. J Clin Sleep Med. 2008 Dec 15; 4(6):536-7. View abstract
  71. Volpp KG, Landrigan CP. Building physician work hour regulations from first principles and best evidence. JAMA. 2008 Sep 10; 300(10):1197-9. View abstract
  72. Landrigan CP, Fahrenkopf AM, Lewin D, Sharek PJ, Barger LK, Eisner M, Edwards S, Chiang VW, Wiedermann BL, Sectish TC. Effects of the accreditation council for graduate medical education duty hour limits on sleep, work hours, and safety. Pediatrics. 2008 Aug; 122(2):250-8. View abstract
  73. Landrigan CP, Conway PH, Stucky ER, Chiang VW, Ottolini MC. Variation in pediatric hospitalists' use of proven and unproven therapies: a study from the Pediatric Research in Inpatient Settings (PRIS) network. J Hosp Med. 2008 Jul; 3(4):292-8. View abstract
  74. Owens JA, Avidan A, Baldwin D, Landrigan C. Improving sleep hygiene. Arch Intern Med. 2008 Jun 09; 168(11):1229-30; author reply 1230. View abstract
  75. Janney M, Landrigan C. Improving nurse working conditions: towards safer models of hospital care. J Hosp Med. 2008 May; 3(3):181-3. View abstract
  76. Walsh KE, Landrigan CP, Adams WG, Vinci RJ, Chessare JB, Cooper MR, Hebert PM, Schainker EG, McLaughlin TJ, Bauchner H. Effect of computer order entry on prevention of serious medication errors in hospitalized children. Pediatrics. 2008 Mar; 121(3):e421-7. View abstract
  77. Fahrenkopf AM, Sectish TC, Barger LK, Sharek PJ, Lewin D, Chiang VW, Edwards S, Wiedermann BL, Landrigan CP. Rates of medication errors among depressed and burnt out residents: prospective cohort study. BMJ. 2008 Mar 01; 336(7642):488-91. View abstract
  78. Lockley SW, Barger LK, Ayas NT, Rothschild JM, Czeisler CA, Landrigan CP. Effects of health care provider work hours and sleep deprivation on safety and performance. Jt Comm J Qual Patient Saf. 2007 Nov; 33(11 Suppl):7-18. View abstract
  79. Landrigan CP, Czeisler CA, Barger LK, Ayas NT, Rothschild JM, Lockley SW. Effective implementation of work-hour limits and systemic improvements. Jt Comm J Qual Patient Saf. 2007 Nov; 33(11 Suppl):19-29. View abstract
  80. Gaies MG, Landrigan CP, Hafler JP, Sandora TJ. Assessing procedural skills training in pediatric residency programs. Pediatrics. 2007 Oct; 120(4):715-22. View abstract
  81. Srivastava R, Landrigan CP, Ross-Degnan D, Soumerai SB, Homer CJ, Goldmann DA, Muret-Wagstaff S. Impact of a hospitalist system on length of stay and cost for children with common conditions. Pediatrics. 2007 Aug; 120(2):267-74. View abstract
  82. Walsh KE, Adams WG, Bauchner H, Vinci RJ, Chessare JB, Cooper MR, Hebert PM, Schainker EG, Landrigan CP. Medication errors related to computerized order entry for children. Pediatrics. 2006 Nov; 118(5):1872-9. View abstract
  83. Landrigan CP, Barger LK, Cade BE, Ayas NT, Czeisler CA. Interns' compliance with accreditation council for graduate medical education work-hour limits. JAMA. 2006 Sep 06; 296(9):1063-70. View abstract
  84. Conway PH, Edwards S, Stucky ER, Chiang VW, Ottolini MC, Landrigan CP. Variations in management of common inpatient pediatric illnesses: hospitalists and community pediatricians. Pediatrics. 2006 Aug; 118(2):441-7. View abstract
  85. Lockley SW, Landrigan CP, Barger LK, Czeisler CA. When policy meets physiology: the challenge of reducing resident work hours. Clin Orthop Relat Res. 2006 Aug; 449:116-27. View abstract
  86. Landrigan CP, Conway PH, Edwards S, Srivastava R. Pediatric hospitalists: a systematic review of the literature. Pediatrics. 2006 May; 117(5):1736-44. View abstract
  87. Lye PS, Rauch DA, Ottolini MC, Landrigan CP, Chiang VW, Srivastava R, Muret-Wagstaff S, Ludwig S. Pediatric hospitalists: report of a leadership conference. Pediatrics. 2006 Apr; 117(4):1122-30. View abstract
  88. Rothschild JM, Hurley AC, Landrigan CP, Cronin JW, Martell-Waldrop K, Foskett C, Burdick E, Czeisler CA, Bates DW. Recovery from medical errors: the critical care nursing safety net. Jt Comm J Qual Patient Saf. 2006 Feb; 32(2):63-72. View abstract
  89. Lilly CM, Landrigan CP. A shift for the better. Chest. 2005 Dec; 128(6):3787-8. View abstract
  90. Landrigan CP. Sliding down the Bell curve: effects of 24-hour work shifts on physicians' cognition and performance. Sleep. 2005 Nov; 28(11):1351-3. View abstract
  91. McBride SC, Chiang VW, Goldmann DA, Landrigan CP. Preventable adverse events in infants hospitalized with bronchiolitis. Pediatrics. 2005 Sep; 116(3):603-8. View abstract
  92. Rothschild JM, Landrigan CP, Cronin JW, Kaushal R, Lockley SW, Burdick E, Stone PH, Lilly CM, Katz JT, Czeisler CA, Bates DW. The Critical Care Safety Study: The incidence and nature of adverse events and serious medical errors in intensive care. Crit Care Med. 2005 Aug; 33(8):1694-700. View abstract
  93. Landrigan CP. The safety of inpatient pediatrics: preventing medical errors and injuries among hospitalized children. Pediatr Clin North Am. 2005 Aug; 52(4):979-93, vii. View abstract
  94. Landrigan CP, Lockley SW, Czeisler CA. Effect of intern's consecutive work hours on safety, medical education and professionalism. Crit Care. 2005 Oct 05; 9(5):528-30; author reply 528-30. View abstract
  95. Lockley SW, Cronin JW, Evans EE, Cade BE, Lee CJ, Landrigan CP, Rothschild JM, Katz JT, Lilly CM, Stone PH, Aeschbach D, Czeisler CA. Effect of reducing interns' weekly work hours on sleep and attentional failures. N Engl J Med. 2004 Oct 28; 351(18):1829-37. View abstract
  96. Landrigan CP, Rothschild JM, Cronin JW, Kaushal R, Burdick E, Katz JT, Lilly CM, Stone PH, Lockley SW, Bates DW, Czeisler CA. Effect of reducing interns' work hours on serious medical errors in intensive care units. N Engl J Med. 2004 Oct 28; 351(18):1838-48. View abstract
  97. Willson DF, Landrigan CP, Horn SD, Smout RJ. Complications in infants hospitalized for bronchiolitis or respiratory syncytial virus pneumonia. J Pediatr. 2003 Nov; 143(5 Suppl):S142-9. View abstract
  98. Fortescue EB, Kaushal R, Landrigan CP, McKenna KJ, Clapp MD, Federico F, Goldmann DA, Bates DW. Prioritizing strategies for preventing medication errors and adverse drug events in pediatric inpatients. Pediatrics. 2003 Apr; 111(4 Pt 1):722-9. View abstract
  99. Olsen SJ, Bleasdale SC, Magnano AR, Landrigan C, Holland BH, Tauxe RV, Mintz ED, Luby S. Outbreaks of typhoid fever in the United States, 1960-99. Epidemiol Infect. 2003 Feb; 130(1):13-21. View abstract
  100. Landrigan CP, Muret-Wagstaff S, Chiang VW, Nigrin DJ, Goldmann DA, Finkelstein JA. Senior resident autonomy in a pediatric hospitalist system. Arch Pediatr Adolesc Med. 2003 Feb; 157(2):206-7. View abstract
  101. Bunyavanich S, Landrigan CP, McMichael AJ, Epstein PR. The impact of climate change on child health. Ambul Pediatr. 2003 Jan-Feb; 3(1):44-52. View abstract
  102. Landrigan CP, Srivastava R, Muret-Wagstaff S, Soumerai SB, Ross-Degnan D, Graef JW, Homer CJ, Goldmann DA. Impact of a health maintenance organization hospitalist system in academic pediatrics. Pediatrics. 2002 Oct; 110(4):720-8. View abstract
  103. Landrigan CP, Muret-Wagstaff S, Chiang VW, Nigrin DJ, Goldmann DA, Finkelstein JA. Effect of a pediatric hospitalist system on housestaff education and experience. Arch Pediatr Adolesc Med. 2002 Sep; 156(9):877-83. View abstract
  104. Nigrovic LE, Lumeng C, Landrigan C, Chiang VW. Rotavirus cerebellitis? Clin Infect Dis. 2002 Jan 01; 34(1):130. View abstract
  105. Srivastava R, Landrigan C, Gidwani P, Harary OH, Muret-Wagstaff S, Homer CJ. Pediatric hospitalists in Canada and the United States: a survey of pediatric academic department chairs. Ambul Pediatr. 2001 Nov-Dec; 1(6):338-9. View abstract
  106. Landrigan C, Srivastava R, Muret-Wagstaff S, Dyck IJ, Homer CJ, Goldmann DA. Pediatric hospitalists: what do we know, and where do we go from here? Ambul Pediatr. 2001 Nov-Dec; 1(6):340-5. View abstract
  107. Landrigan C. Preventable deaths and injuries during magnetic resonance imaging. N Engl J Med. 2001 Sep 27; 345(13):1000-1. View abstract
  108. Kaushal R, Bates DW, Landrigan C, McKenna KJ, Clapp MD, Federico F, Goldmann DA. Medication errors and adverse drug events in pediatric inpatients. JAMA. 2001 Apr 25; 285(16):2114-20. View abstract
  109. Kim R, Landrigan C, Mossmann P, Sparrow D, Hu H. Age and secular trends in bone lead levels in middle-aged and elderly men: three-year longitudinal follow-up in the Normative Aging Study. Am J Epidemiol. 1997 Oct 01; 146(7):586-91. View abstract