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Researcher Areas

  • Anti-obesity drug discovery
  • Leptin resistence

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PUBLICATIONS

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  1. Feng X, Guan D, Auen T, Choi JW, Salazar-Hernandez MA, Faruk F, Copps KD, Ozcan U. Lipocalin 2 Does Not Play A Role in Celastrol-Mediated Reduction in Food Intake and Body Weight. Sci Rep. 2019 Sep 05; 9(1):12809. View abstract
  2. Feng X, Guan D, Auen T, Choi JW, Salazar Hernández MA, Lee J, Chun H, Faruk F, Kaplun E, Herbert Z, Copps KD, Ozcan U. IL1R1 is required for celastrol's leptin-sensitization and antiobesity effects. Nat Med. 2019 04; 25(4):575-582. View abstract
  3. Lee J, Liu J, Feng X, Salazar Hernández MA, Mucka P, Ibi D, Choi JW, Ozcan U. Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice. Nat Med. 2016 09; 22(9):1023-32. View abstract