Research Overview

Dr. Chen has focused much of her clinical research efforts on the diagnosis and amelioration of late cardiac effects in cancer survivors—attempting to understand treatment-related cardiac effects in patients currently undergoing cancer treatment. As an expert in cardiac noninvasive imaging, Dr. Chen’s approach is preventative and one of non-invasive screening to detect cardiovascular issue earlier in its course. 

Twenty years ago, Dr. Chen began investigating the genetics and clinical cardiovascular ramifications of periventricular nodular heterotopia (PVNH), as well as the filamin A mutation that has been implicated as a causal factor in this multi-system disorder. She has helped analyze mechanisms of congenital heart disease in this population along with describing its clinical association with Ehlers-Danlos Syndrome. To improve the lives of patients with PVNH and cardiovascular disease, she is the founder and leader of the C-BrDG (pronounced C-Bridge) (Cardiology of Brain Development in Genetics Program).

About Ming Hui Chen, MD, MSc

Dr. Chen, a graduate of Princeton University and Harvard Medical School, trained as an internist and cardiologist at Massachusetts General Hospital. She also has a master’s degree in clinical investigation from Harvard Medical School. She now serves as an attending cardiologist at Boston Children’s Hospital. Dr. Chen has been on-staff at the Harvard Teaching Hospital for more than 25 years.

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