Research Overview

Charles Berde's research focuses on relieving neuropathic pain in children. The Pain Treatment Service at Children's Hospital in Boston has become a referral center for children with many types of neuropathic pain, but especially limb pain associated with signs of abnormal circulation, which has been variously named reflex sympathetic (or neurovascular) dystrophy (RSD/RND), sympathetically maintained pain (SMP), and complex regional pain syndrome type 1 (CRPS1). 

About Charles Berde

Charles Berde received an MD and PhD from Stanford University School of Medicine. He completed an internship and residency in pediatrics at Children's Hospital Boston, a residency in anesthesia at Massachusetts General Hospital, and a fellowship in pediatric anesthesia at Children's Hospital. He has received several awards and honors for his pioneering work in pediatric pain relief, including the 2003 Scientific Achievement Award of the Reflex Sympathetic Dystrophy Syndrome Association. He was profiled as one of Time Magazine's "Heroes in Medicine" in 1997.

Researcher Services

Researcher Areas

  • Pain Management

Research Departments

Research Divisions

PUBLICATIONS

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  1. Szmuk P, Andropoulos D, McGowan F, Brambrink A, Lee C, Lee KJ, McCann ME, Liu Y, Saynhalath R, Bong CL, Anderson BJ, Berde C, de Graaff JC, Disma N, Kurth D, Loepke A, Orser B, Sessler DI, Skowno JJ, von Ungern-Sternberg BS, Vutskits L, Davidson A. An Open Label Pilot Study of a Dexmedetomidine-Remifentanil-Caudal Anesthetic for Infant Lower Abdominal/Lower Extremity Surgery: The T REX Pilot Study. Paediatr Anaesth. 2018 Nov 14. View abstract
  2. Tsui BCH, Boretsky K, Berde C. Maximum Recommended Dosage of Ropivacaine and Bupivacaine for Pediatric Regional Anesthesia. Reg Anesth Pain Med. 2018 11; 43(8):895-896. View abstract
  3. Koechlin H, Donado C, Berde CB, Kossowsky J. Effects of Childhood Life Events on Adjustment Problems in Adolescence: A Longitudinal Study. J Dev Behav Pediatr. 2018 Oct/Nov; 39(8):629-641. View abstract
  4. Sieberg CB, Taras C, Gomaa A, Nickerson C, Wong C, Ward C, Baskozos G, Bennett DLH, Ramirez JD, Themistocleous AC, Rice ASC, Shillo PR, Tesfaye S, Edwards RR, Andrews NA, Berde C, Costigan M. Neuropathic pain drives anxiety behavior in mice, results consistent with anxiety levels in diabetic neuropathy patients. Pain Rep. 2018 May; 3(3):e651. View abstract
  5. Cornelissen L, Kim SE, Lee JM, Brown EN, Purdon PL, Berde CB. Electroencephalographic markers of brain development during sevoflurane anaesthesia in children up to 3 years old. Br J Anaesth. 2018 Jun; 120(6):1274-1286. View abstract
  6. Walco GA, Kopecky EA, Weisman SJ, Stinson J, Stevens B, Desjardins PJ, Berde CB, Krane EJ, Anand KJS, Yaster M, Dampier CD, Dworkin RH, Gilron I, Lynn AM, Maxwell LG, Raja S, Schachtel B, Turk DC. Clinical trial designs and models for analgesic medications for acute pain in neonates, infants, toddlers, children, and adolescents: ACTTION recommendations. Pain. 2018 Feb; 159(2):193-205. View abstract
  7. Cornelissen L, Donado C, Lee JM, Liang NE, Mills I, Tou A, Bilge A, Berde CB. Clinical signs and electroencephalographic patterns of emergence from sevoflurane anaesthesia in children: An observational study. Eur J Anaesthesiol. 2018 Jan; 35(1):49-59. View abstract
  8. Simons LE, Sieberg CB, Conroy C, Randall ET, Shulman J, Borsook D, Berde C, Sethna NF, Logan DE. Children With Chronic Pain: Response Trajectories After Intensive Pain Rehabilitation Treatment. J Pain. 2018 Feb; 19(2):207-218. View abstract
  9. Donado C, Lobo K, Velarde-Álvarez MF, Kim J, Kenney A, Logan D, Berde CB. Continuous Regional Anesthesia and Inpatient Rehabilitation for Pediatric Complex Regional Pain Syndrome. Reg Anesth Pain Med. 2017 Jul/Aug; 42(4):527-534. View abstract
  10. Cornelissen L, Bergin AM, Lobo K, Donado C, Soul JS, Berde CB. Electroencephalographic discontinuity during sevoflurane anesthesia in infants and children. Paediatr Anaesth. 2017 Mar; 27(3):251-262. View abstract
  11. Robinson S, Robertson FC, Dasenbrock HH, O'Brien CP, Berde C, Padua H. Image-guided intrathecal baclofen pump catheter implantation: a technical note and case series. J Neurosurg Spine. 2017 May; 26(5):621-627. View abstract
  12. Peake RW, Zhang VY, Azcue N, Hartigan CE, Shkreta A, Prabhakara J, Berde CB, Kellogg MD. Measurement of neosaxitoxin in human plasma using liquid-chromatography tandem mass spectrometry: Proof of concept for a pharmacokinetic application. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Nov 15; 1036-1037:42-49. View abstract
  13. Cornelissen L, Berde C. Biomedical science: Protection for anaesthetized mice. Nature. 2016 08 04; 536(7614):36-7. View abstract
  14. Berde C, Koka A, Donado-Rincon C. Lidocaine Infusions and Other Options for Opioid-Resistant Pain Due to Pediatric Advanced Cancer. Pediatr Blood Cancer. 2016 07; 63(7):1141-3. View abstract
  15. Chalkiadis GA, Berde C. Bundled analgesia interventions for day-stay surgery. Paediatr Anaesth. 2016 Feb; 26(2):120-1. View abstract
  16. Simons LE, Erpelding N, Hernandez JM, Serrano P, Zhang K, Lebel AA, Sethna NF, Berde CB, Prabhu SP, Becerra L, Borsook D. Fear and Reward Circuit Alterations in Pediatric CRPS. Front Hum Neurosci. 2015; 9:703. View abstract
  17. Kurgansky KE, Rodriguez ST, Kralj MS, Mooney JJ, Dinakar P, d'Hemecourt PA, Hedequist DJ, Proctor MR, Berde CB. Epidural Steroid Injections for Radiculopathy and/or Back Pain in Children and Adolescents: A Retrospective Cohort Study With a Prospective Follow-Up. Reg Anesth Pain Med. 2016 Jan-Feb; 41(1):86-92. View abstract
  18. Davidson AJ, Disma N, de Graaff JC, Withington DE, Dorris L, Bell G, Stargatt R, Bellinger DC, Schuster T, Arnup SJ, Hardy P, Hunt RW, Takagi MJ, Giribaldi G, Hartmann PL, Salvo I, Morton NS, von Ungern Sternberg BS, Locatelli BG, Wilton N, Lynn A, Thomas JJ, Polaner D, Bagshaw O, Szmuk P, Absalom AR, Frawley G, Berde C, Ormond GD, Marmor J, McCann ME. Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial. Lancet. 2016 Jan 16; 387(10015):239-50. View abstract
  19. Poorun R, Hartley C, Goksan S, Worley A, Boyd S, Cornelissen L, Berde C, Rogers R, Ali T, Slater R. Electroencephalography during general anaesthesia differs between term-born and premature-born children. Clin Neurophysiol. 2016 Feb; 127(2):1216-1222. View abstract
  20. Lobo K, Donado C, Cornelissen L, Kim J, Ortiz R, Peake RW, Kellogg M, Alexander ME, Zurakowski D, Kurgansky KE, Peyton J, Bilge A, Boretsky K, McCann ME, Berde CB, Cravero J. A Phase 1, Dose-escalation, Double-blind, Block-randomized, Controlled Trial of Safety and Efficacy of Neosaxitoxin Alone and in Combination with 0.2% Bupivacaine, with and without Epinephrine, for Cutaneous Anesthesia. Anesthesiology. 2015 Oct; 123(4):873-85. View abstract
  21. Templin JS, Wylie MC, Kim JD, Kurgansky KE, Gorski G, Kheir J, Zurakowski D, Corfas G, Berde C. Neosaxitoxin in Rat Sciatic Block: Improved Therapeutic Index Using Combinations with Bupivacaine, with and without Epinephrine. Anesthesiology. 2015 Oct; 123(4):886-98. View abstract
  22. Cornelissen L, Kim SE, Purdon PL, Brown EN, Berde CB. Age-dependent electroencephalogram (EEG) patterns during sevoflurane general anesthesia in infants. Elife. 2015 Jun 23; 4:e06513. View abstract
  23. Garibyan L, Cornelissen L, Sipprell W, Pruessner J, Elmariah S, Luo T, Lerner EA, Jung Y, Evans C, Zurakowski D, Berde CB, Rox Anderson R. Transient Alterations of Cutaneous Sensory Nerve Function by Noninvasive Cryolipolysis. J Invest Dermatol. 2015 Nov; 135(11):2623-2631. View abstract
  24. Berde C. Developing better local anesthetics. Anesth Analg. 2015 Apr; 120(4):718-20. View abstract
  25. Bajic D, Soiza-Reilly M, Spalding AL, Berde CB, Commons KG. Endogenous cholinergic neurotransmission contributes to behavioral sensitization to morphine. PLoS One. 2015; 10(2):e0117601. View abstract
  26. Kossowsky J, Donado C, Berde CB. Immediate rescue designs in pediatric analgesic trials: a systematic review and meta-analysis. Anesthesiology. 2015 Jan; 122(1):150-171. View abstract
  27. Cornelissen L, Donado C, Kim J, Chiel L, Zurakowski D, Logan DE, Meier P, Sethna NF, Blankenburg M, Zernikow B, Sundel RP, Berde CB. Pain hypersensitivity in juvenile idiopathic arthritis: a quantitative sensory testing study. Pediatr Rheumatol Online J. 2014; 12:39. View abstract
  28. Becerra L, Sava S, Simons LE, Drosos AM, Sethna N, Berde C, Lebel AA, Borsook D. Intrinsic brain networks normalize with treatment in pediatric complex regional pain syndrome. Neuroimage Clin. 2014; 6:347-69. View abstract
  29. Simons LE, Pielech M, Erpelding N, Linnman C, Moulton E, Sava S, Lebel A, Serrano P, Sethna N, Berde C, Becerra L, Borsook D. The responsive amygdala: treatment-induced alterations in functional connectivity in pediatric complex regional pain syndrome. Pain. 2014 Sep; 155(9):1727-42. View abstract
  30. Berde CB, Boretsky KR, Cravero JP. Paravertebral block for analgesia after pediatric thoracic surgery. Reg Anesth Pain Med. 2014 May-Jun; 39(3):179-80. View abstract
  31. Solodiuk JC, Brighton H, McHale J, LoChiatto J, Logan DE, Sager S, Zurakowski D, Berde CB. Documented electronic medical record-based pain intensity scores at a tertiary pediatric medical center: a cohort analysis. J Pain Symptom Manage. 2014 Nov; 48(5):924-33. View abstract
  32. Jerome J, Solodiuk JC, Sethna N, McHale J, Berde C. A single institution's effort to translate codeine knowledge into specific clinical practice. J Pain Symptom Manage. 2014 Jul; 48(1):119-26. View abstract
  33. Rork JF, Berde CB, Goldstein RD. Regional anesthesia approaches to pain management in pediatric palliative care: a review of current knowledge. J Pain Symptom Manage. 2013 Dec; 46(6):859-73. View abstract
  34. Allee JI, Goins KM, Berde CB, McCann ME. A case of cerebrospinal fluid leak in an infant after spinal anesthesia. J Clin Anesth. 2013 May; 25(3):217-9. View abstract
  35. Linnman C, Becerra L, Lebel A, Berde C, Grant PE, Borsook D. Transient and persistent pain induced connectivity alterations in pediatric complex regional pain syndrome. PLoS One. 2013; 8(3):e57205. View abstract
  36. Logan DE, Williams SE, Carullo VP, Claar RL, Bruehl S, Berde CB. Children and adolescents with complex regional pain syndrome: more psychologically distressed than other children in pain? Pain Res Manag. 2013 Mar-Apr; 18(2):87-93. View abstract
  37. Berde C, Greco C. Pediatric regional anesthesia: drawing inferences on safety from prospective registries and case reports. Anesth Analg. 2012 Dec; 115(6):1259-62. View abstract
  38. Logan DE, Carpino EA, Chiang G, Condon M, Firn E, Gaughan VJ, Hogan M, Leslie DS, Olson K, Sager S, Sethna N, Simons LE, Zurakowski D, Berde CB. A day-hospital approach to treatment of pediatric complex regional pain syndrome: initial functional outcomes. Clin J Pain. 2012 Nov-Dec; 28(9):766-74. View abstract
  39. Bajic D, Berde CB, Commons KG. Periaqueductal gray neuroplasticity following chronic morphine varies with age: role of oxidative stress. Neuroscience. 2012 Dec 13; 226:165-77. View abstract
  40. Templin JS, Bang SJ, Soiza-Reilly M, Berde CB, Commons KG. Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas. Brain Res. 2012 May 31; 1457:1-12. View abstract
  41. Wylie MC, Johnson VM, Carpino E, Mullen K, Hauser K, Nedder A, Kheir JN, Rodriguez-Navarro AJ, Zurakowski D, Berde CB. Respiratory, neuromuscular, and cardiovascular effects of neosaxitoxin in isoflurane-anesthetized sheep. Reg Anesth Pain Med. 2012 Mar-Apr; 37(2):152-8. View abstract
  42. Oaklander AL, Wilson PR, Moskovitz PA, Manning DC, Lubenow T, Levine JD, Harden RN, Galer BS, Cooper MS, Bruehl S, Broatch J, Berde C, Bennett GJ. Response to "A new definition of neuropathic pain". Pain. 2012 Apr; 153(4):934-5; author reply 935-6. View abstract
  43. Berde CB, Walco GA, Krane EJ, Anand KJ, Aranda JV, Craig KD, Dampier CD, Finkel JC, Grabois M, Johnston C, Lantos J, Lebel A, Maxwell LG, McGrath P, Oberlander TF, Schanberg LE, Stevens B, Taddio A, von Baeyer CL, Yaster M, Zempsky WT. Pediatric analgesic clinical trial designs, measures, and extrapolation: report of an FDA scientific workshop. Pediatrics. 2012 Feb; 129(2):354-64. View abstract
  44. Sethna NF, Berde CB. Sympathetic nerve blocks, pragmatic trials, and responder analysis. Anesthesiology. 2012 Jan; 116(1):12-4. View abstract
  45. Berde CB, Athiraman U, Yahalom B, Zurakowski D, Corfas G, Bognet C. Tetrodotoxin-bupivacaine-epinephrine combinations for prolonged local anesthesia. Mar Drugs. 2011 Dec; 9(12):2717-28. View abstract
  46. Yahalom B, Athiraman U, Soriano SG, Zurakowski D, Carpino EA, Corfas G, Berde CB. Spinal anesthesia in infant rats: development of a model and assessment of neurologic outcomes. Anesthesiology. 2011 Jun; 114(6):1325-35. View abstract
  47. Rodríguez-Navarro AJ, Berde CB, Wiedmaier G, Mercado A, Garcia C, Iglesias V, Zurakowski D. Comparison of neosaxitoxin versus bupivacaine via port infiltration for postoperative analgesia following laparoscopic cholecystectomy: a randomized, double-blind trial. Reg Anesth Pain Med. 2011 Mar-Apr; 36(2):103-9. View abstract
  48. Simons LE, Sieberg CB, Carpino E, Logan D, Berde C. The Fear of Pain Questionnaire (FOPQ): assessment of pain-related fear among children and adolescents with chronic pain. J Pain. 2011 Jun; 12(6):677-86. View abstract
  49. Ullrich CK, Dussel V, Hilden JM, Sheaffer JW, Moore CL, Berde CB, Wolfe J. Fatigue in children with cancer at the end of life. J Pain Symptom Manage. 2010 Oct; 40(4):483-94. View abstract
  50. Berde CB, Stevens B. Blood sampling and other needle procedures - the Achilles heel of newborn intensive care. Pain. 2009 Dec 15; 147(1-3):15-6. View abstract
  51. Berde C, McGrath P. Pain measurement and Beecher's challenge: 50 years later. Anesthesiology. 2009 Sep; 111(3):473-4. View abstract
  52. Meier PM, Zurakowski D, Berde CB, Sethna NF. Lumbar sympathetic blockade in children with complex regional pain syndromes: a double blind placebo-controlled crossover trial. Anesthesiology. 2009 Aug; 111(2):372-80. View abstract
  53. Sava S, Lebel AA, Leslie DS, Drosos A, Berde C, Becerra L, Borsook D. Challenges of functional imaging research of pain in children. Mol Pain. 2009 Jun 16; 5:30. View abstract
  54. Ababneh ZQ, Beloeil H, Berde CB, Ababneh AM, Maier SE, Mulkern RV. In vivo lipid diffusion coefficient measurements in rat bone marrow. Magn Reson Imaging. 2009 Jul; 27(6):859-64. View abstract
  55. Lebel A, Becerra L, Wallin D, Moulton EA, Morris S, Pendse G, Jasciewicz J, Stein M, Aiello-Lammens M, Grant E, Berde C, Borsook D. fMRI reveals distinct CNS processing during symptomatic and recovered complex regional pain syndrome in children. Brain. 2008 Jul; 131(Pt 7):1854-79. View abstract
  56. Berde C, Nurko S. Opioid side effects--mechanism-based therapy. N Engl J Med. 2008 May 29; 358(22):2400-2. View abstract
  57. Wolfe J, Hammel JF, Edwards KE, Duncan J, Comeau M, Breyer J, Aldridge SA, Grier HE, Berde C, Dussel V, Weeks JC. Easing of suffering in children with cancer at the end of life: is care changing? J Clin Oncol. 2008 Apr 01; 26(10):1717-23. View abstract
  58. Needleman HL, Harpavat S, Wu S, Allred EN, Berde C. Postoperative pain and other sequelae of dental rehabilitations performed on children under general anesthesia. Pediatr Dent. 2008 Mar-Apr; 30(2):111-21. View abstract
  59. Berde CB, Yaster M, Meretoja O, McCann ME, Huledal G, Gustafsson U, Larsson LE. Stable plasma concentrations of unbound ropivacaine during postoperative epidural infusion for 24-72 hours in children. Eur J Anaesthesiol. 2008 May; 25(5):410-7. View abstract
  60. Dimitrakov J, Kroenke K, Steers WD, Berde C, Zurakowski D, Freeman MR, Jackson JL. Pharmacologic management of painful bladder syndrome/interstitial cystitis: a systematic review. Arch Intern Med. 2007 Oct 08; 167(18):1922-9. View abstract
  61. Wen YR, Suter MR, Kawasaki Y, Huang J, Pertin M, Kohno T, Berde CB, Decosterd I, Ji RR. Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model. Anesthesiology. 2007 Aug; 107(2):312-21. View abstract
  62. Sethna NF, Meier PM, Zurakowski D, Berde CB. Cutaneous sensory abnormalities in children and adolescents with complex regional pain syndromes. Pain. 2007 Sep; 131(1-2):153-61. View abstract
  63. Beloeil H, Ababneh Z, Chung R, Zurakowski D, Mulkern RV, Berde CB. Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 1): hyperalgesia, edema, and systemic cytokines. Anesthesiology. 2006 Jul; 105(1):128-38. View abstract
  64. Beloeil H, Ji RR, Berde CB. Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 2): cytokines and p38 mitogen-activated protein kinases in dorsal root ganglia and spinal cord. Anesthesiology. 2006 Jul; 105(1):139-45. View abstract
  65. Ullrich CK, Hilden JM, Sheaffer JW, Moore CL, Berde CB, Weeks JC, Wolfe J. Factors associated with fatigue in children with cancer at the end of life. J Clin Oncol. 2006 Jun 20; 24(18_suppl):8574. View abstract
  66. Meier PM, Alexander ME, Sethna NF, De Jong-De Vos Van Steenwijk CC, Zurakowski D, Berde CB. Complex regional pain syndromes in children and adolescents: regional and systemic signs and symptoms and hemodynamic response to tilt table testing. Clin J Pain. 2006 May; 22(4):399-406. View abstract
  67. Anand KJ, Aranda JV, Berde CB, Buckman S, Capparelli EV, Carlo W, Hummel P, Johnston CC, Lantos J, Tutag-Lehr V, Lynn AM, Maxwell LG, Oberlander TF, Raju TN, Soriano SG, Taddio A, Walco GA. Summary proceedings from the neonatal pain-control group. Pediatrics. 2006 Mar; 117(3 Pt 2):S9-S22. View abstract
  68. Lin YC, Lee AC, Kemper KJ, Berde CB. Use of complementary and alternative medicine in pediatric pain management service: a survey. Pain Med. 2005 Nov-Dec; 6(6):452-8. View abstract
  69. Ababneh Z, Beloeil H, Berde CB, Gambarota G, Maier SE, Mulkern RV. Biexponential parameterization of diffusion and T2 relaxation decay curves in a rat muscle edema model: decay curve components and water compartments. Magn Reson Med. 2005 Sep; 54(3):524-31. View abstract
  70. Greco C, Berde C. Pain management for the hospitalized pediatric patient. Pediatr Clin North Am. 2005 Aug; 52(4):995-1027, vii-viii. View abstract
  71. Tsui BC, Berde CB. Caudal analgesia and anesthesia techniques in children. Curr Opin Anaesthesiol. 2005 Jun; 18(3):283-8. View abstract
  72. Anand KJ, Aranda JV, Berde CB, Buckman S, Capparelli EV, Carlo WA, Hummel P, Lantos J, Johnston CC, Lehr VT, Lynn AM, Maxwell LG, Oberlander TF, Raju TN, Soriano SG, Taddio A, Walco GA. Analgesia and anesthesia for neonates: study design and ethical issues. Clin Ther. 2005 Jun; 27(6):814-43. View abstract
  73. Berde CB, Jaksic T, Lynn AM, Maxwell LG, Soriano SG, Tibboel D. Anesthesia and analgesia during and after surgery in neonates. Clin Ther. 2005 Jun; 27(6):900-21. View abstract
  74. Sethna NF, Verghese ST, Hannallah RS, Solodiuk JC, Zurakowski D, Berde CB. A randomized controlled trial to evaluate S-Caine patch for reducing pain associated with vascular access in children. Anesthesiology. 2005 Feb; 102(2):403-8. View abstract
  75. Berde CB, Lebel A. Complex regional pain syndromes in children and adolescents. Anesthesiology. 2005 Feb; 102(2):252-5. View abstract
  76. Masuda T, Cairns BE, Sadhasivam S, Dunning PS, Berde CB. Epinephrine prevents muscle blood flow increases after perineural injection of tetrodotoxin. Anesthesiology. 2004 Dec; 101(6):1428-34. View abstract
  77. McCann ME, Waters P, Goumnerova LC, Berde C. Self-mutilation in young children following brachial plexus birth injury. Pain. 2004 Jul; 110(1-2):123-9. View abstract
  78. Berde C. Local anesthetics in infants and children: an update. Paediatr Anaesth. 2004 May; 14(5):387-93. View abstract
  79. Lin YC, Bioteau AB, Ferrari LR, Berde CB. The use of herbs and complementary and alternative medicine in pediatric preoperative patients. J Clin Anesth. 2004 Feb; 16(1):4-6. View abstract
  80. Wang C, Liu H, Wilder RT, Berde CB. Effects of repeated injection of local anesthetic on sciatic nerve blocks response. J Huazhong Univ Sci Technolog Med Sci. 2004; 24(5):497-9. View abstract
  81. Suter MR, Papaloïzos M, Berde CB, Woolf CJ, Gilliard N, Spahn DR, Decosterd I. Development of neuropathic pain in the rat spared nerve injury model is not prevented by a peripheral nerve block. Anesthesiology. 2003 Dec; 99(6):1402-8. View abstract
  82. Kohane DS, Smith SE, Louis DN, Colombo G, Ghoroghchian P, Hunfeld NG, Berde CB, Langer R. Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres. Pain. 2003 Jul; 104(1-2):415-21. View abstract
  83. Cairns BE, Svensson P, Wang K, Hupfeld S, Graven-Nielsen T, Sessle BJ, Berde CB, Arendt-Nielsen L. Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle. J Neurophysiol. 2003 Oct; 90(4):2098-105. View abstract
  84. Berde CB, Brennan TJ, Raja SN. Opioids: more to learn, improvements to be made. Anesthesiology. 2003 Jun; 98(6):1309-12. View abstract
  85. Berde C, Wolfe J. Pain, anxiety, distress, and suffering: interrelated, but not interchangeable. J Pediatr. 2003 Apr; 142(4):361-3. View abstract
  86. Cairns BE, Gambarota G, Dunning PS, Mulkern RV, Berde CB. Activation of peripheral excitatory amino acid receptors decreases the duration of local anesthesia. Anesthesiology. 2003 Feb; 98(2):521-9. View abstract
  87. Berde CB, Sethna NF. Analgesics for the treatment of pain in children. N Engl J Med. 2002 Oct 03; 347(14):1094-103. View abstract
  88. Palmer GM, Cairns BE, Berkes SL, Dunning PS, Taylor GA, Berde CB. The effects of lidocaine and adrenergic agonists on rat sciatic nerve and skeletal muscle blood flow in vivo. Anesth Analg. 2002 Oct; 95(4):1080-6, table of contents. View abstract
  89. Teitelbaum JE, Berde CB, Nurko S, Buonomo C, Perez-Atayde AR, Fox VL. Diagnosis and management of MNGIE syndrome in children: case report and review of the literature. J Pediatr Gastroenterol Nutr. 2002 Sep; 35(3):377-83. View abstract
  90. Lee BH, Scharff L, Sethna NF, McCarthy CF, Scott-Sutherland J, Shea AM, Sullivan P, Meier P, Zurakowski D, Masek BJ, Berde CB. Physical therapy and cognitive-behavioral treatment for complex regional pain syndromes. J Pediatr. 2002 Jul; 141(1):135-40. View abstract
  91. Palmer GM, Sundel R, Berde CB, Sethna NF. Prolonged sensory and motor deficit following short-term lumbar epidural analgesia in a patient with mixed connective tissue disease. J Pain Symptom Manage. 2002 Feb; 23(2):89-92. View abstract
  92. Cairns BE, Gambarota G, Svensson P, Arendt-Nielsen L, Berde CB. Glutamate-induced sensitization of rat masseter muscle fibers. Neuroscience. 2002; 109(2):389-99. View abstract
  93. McCann ME, Sethna NF, Mazoit JX, Sakamoto M, Rifai N, Hope T, Sullivan L, Auble SG, Berde CB. The pharmacokinetics of epidural ropivacaine in infants and young children. Anesth Analg. 2001 Oct; 93(4):893-7. View abstract
  94. Meier PM, Berde CB, DiCanzio J, Zurakowski D, Sethna NF. Quantitative assessment of cutaneous thermal and vibration sensation and thermal pain detection thresholds in healthy children and adolescents. Muscle Nerve. 2001 Oct; 24(10):1339-45. View abstract
  95. Gambarota G, Cairns BE, Berde CB, Mulkern RV. Osmotic effects on the T2 relaxation decay of in vivo muscle. Magn Reson Med. 2001 Sep; 46(3):592-9. View abstract
  96. Wang C, Sholas MG, Berde CB, DiCanzio J, Zurakowski D, Wilder RT. Evidence that spinal segmental nitric oxide mediates tachyphylaxis to peripheral local anesthetic nerve block. Acta Anaesthesiol Scand. 2001 Sep; 45(8):945-53. View abstract
  97. Kohane DS, Lu NT, Crosa GA, Kuang Y, Berde CB. High concentrations of adrenergic antagonists prolong sciatic nerve blockade by tetrodotoxin. Acta Anaesthesiol Scand. 2001 Aug; 45(7):899-905. View abstract
  98. Kohane DS, Lu NT, Cairns BE, Berde CB. Effects of adrenergic agonists and antagonists on tetrodotoxin-induced nerve block. Reg Anesth Pain Med. 2001 May-Jun; 26(3):239-45. View abstract
  99. Berde C, Cairns B. Developmental pharmacology across species: promise and problems. Anesth Analg. 2000 Jul; 91(1):1-5. View abstract
  100. Needleman HL, Hoang CD, Allred E, Hertzberg J, Berde C. Reports of pain by children undergoing rapid palatal expansion. Pediatr Dent. 2000 May-Jun; 22(3):221-6. View abstract
  101. Kemper KJ, Sarah R, Silver-Highfield E, Xiarhos E, Barnes L, Berde C. On pins and needles? Pediatric pain patients' experience with acupuncture. Pediatrics. 2000 Apr; 105(4 Pt 2):941-7. View abstract
  102. Kohane DS, Lu NT, Gökgöl-Kline AC, Shubina M, Kuang Y, Hall S, Strichartz GR, Berde CB. The local anesthetic properties and toxicity of saxitonin homologues for rat sciatic nerve block in vivo. Reg Anesth Pain Med. 2000 Jan-Feb; 25(1):52-9. View abstract
  103. Lee AC, Highfield ES, Berde CB, Kemper KJ. Survey of acupuncturists: practice characteristics and pediatric care. West J Med. 1999 Sep; 171(3):153-7. View abstract
  104. Shenkman Z, Holzman RS, Kim C, Ferrari LR, DiCanzio J, Highfield ES, Van Keuren K, Kaptchuk T, Kenna MA, Berde CB, Rockoff MA. Acupressure-acupuncture antiemetic prophylaxis in children undergoing tonsillectomy. Anesthesiology. 1999 May; 90(5):1311-6. View abstract
  105. Fauza DO, Berde CB, Fishman SJ. Prolonged local myometrial blockade prevents preterm labor after fetal surgery in a leporine model. J Pediatr Surg. 1999 Apr; 34(4):540-2. View abstract
  106. Kohane DS, Kuang Y, Lu NT, Langer R, Strichartz GR, Berde CB. Vanilloid receptor agonists potentiate the in vivo local anesthetic activity of percutaneously injected site 1 sodium channel blockers. Anesthesiology. 1999 Feb; 90(2):524-34. View abstract
  107. Kohane DS, Sankar WN, Shubina M, Hu D, Rifai N, Berde CB. Sciatic nerve blockade in infant, adolescent, and adult rats: a comparison of ropivacaine with bupivacaine. Anesthesiology. 1998 Nov; 89(5):1199-208; discussion 10A. View abstract
  108. Dräger C, Benziger D, Gao F, Berde CB. Prolonged intercostal nerve blockade in sheep using controlled-release of bupivacaine and dexamethasone from polymer microspheres. Anesthesiology. 1998 Oct; 89(4):969-79. View abstract
  109. Kohane DS, Yieh J, Lu NT, Langer R, Strichartz GR, Berde CB. A re-examination of tetrodotoxin for prolonged duration local anesthesia. Anesthesiology. 1998 Jul; 89(1):119-31. View abstract
  110. Robinson WM, Ravilly S, Berde C, Wohl ME. End-of-life care in cystic fibrosis. Pediatrics. 1997 Aug; 100(2 Pt 1):205-9. View abstract
  111. Hu D, Hu R, Berde CB. Neurologic evaluation of infant and adult rats before and after sciatic nerve blockade. Anesthesiology. 1997 Apr; 86(4):957-65. View abstract
  112. Charles Berde and Robert Langer. "Biodegradable polymer matrices for sustained delivery of local anesthetic agents". 1997. View abstract
  113. Charles Berde and Robert Langer. "Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid". 1997. View abstract
  114. Wilder RT, Sholas MG, Berde CB. NG-nitro-L-arginine methyl ester (L-NAME) prevents tachyphylaxis to local anesthetics in a dose-dependent manner. Anesth Analg. 1996 Dec; 83(6):1251-5. View abstract
  115. Oberlander TF, Berde CB, Saul JP. Halothane and cardiac autonomic control in infants: assessment with quantitative respiratory sinus arrhythmia. Pediatr Res. 1996 Nov; 40(5):710-7. View abstract
  116. Castillo J, Curley J, Hotz J, Uezono M, Tigner J, Chasin M, Wilder R, Langer R, Berde C. Glucocorticoids prolong rat sciatic nerve blockade in vivo from bupivacaine microspheres. Anesthesiology. 1996 Nov; 85(5):1157-66. View abstract
  117. Berde C. Regional anesthesia in children: what have we learned? Anesth Analg. 1996 Nov; 83(5):897-900. View abstract
  118. Collins JJ, Geake J, Grier HE, Houck CS, Thaler HT, Weinstein HJ, Twum-Danso NY, Berde CB. Patient-controlled analgesia for mucositis pain in children: a three-period crossover study comparing morphine and hydromorphone. J Pediatr. 1996 Nov; 129(5):722-8. View abstract
  119. Ravilly S, Robinson W, Suresh S, Wohl ME, Berde CB. Chronic pain in cystic fibrosis. Pediatrics. 1996 Oct; 98(4 Pt 1):741-7. View abstract
  120. Houck CS, Wilder RT, McDermott JS, Sethna NF, Berde CB. Safety of intravenous ketorolac therapy in children and cost savings with a unit dosing system. J Pediatr. 1996 Aug; 129(2):292-6. View abstract
  121. Yaster M, Kost-Byerly S, Berde C, Billet C. The management of opioid and benzodiazepine dependence in infants, children, and adolescents. Pediatrics. 1996 Jul; 98(1):135-40. View abstract
  122. Curley J, Castillo J, Hotz J, Uezono M, Hernandez S, Lim JO, Tigner J, Chasin M, Langer R, Berde C. Prolonged regional nerve blockade. Injectable biodegradable bupivacaine/polyester microspheres. Anesthesiology. 1996 Jun; 84(6):1401-10. View abstract
  123. Collins JJ, Grier HE, Sethna NF, Wilder RT, Berde CB. Regional anesthesia for pain associated with terminal pediatric malignancy. Pain. 1996 Apr; 65(1):63-9. View abstract
  124. Collins JJ, Berde CB, Grier HE, Nachmanoff DB, Kinney HC. Massive opioid resistance in an infant with a localized metastasis to the midbrain periaqueductal gray. Pain. 1995 Nov; 63(2):271-5. View abstract
  125. Collins JJ, Kerner J, Sentivany S, Berde CB. Intravenous amitriptyline in pediatrics. J Pain Symptom Manage. 1995 Aug; 10(6):471-5. View abstract
  126. Berde C. Pediatric oncology procedures: to sleep or perchance to dream? Pain. 1995 Jul; 62(1):1-2. View abstract
  127. Collins JJ, Grier HE, Kinney HC, Berde CB. Control of severe pain in children with terminal malignancy. J Pediatr. 1995 Apr; 126(4):653-7. View abstract
  128. Strafford MA, Wilder RT, Berde CB. The risk of infection from epidural analgesia in children: a review of 1620 cases. Anesth Analg. 1995 Feb; 80(2):234-8. View abstract
  129. Rusy LM, Houck CS, Sullivan LJ, Ohlms LA, Jones DT, McGill TJ, Berde CB. A double-blind evaluation of ketorolac tromethamine versus acetaminophen in pediatric tonsillectomy: analgesia and bleeding. Anesth Analg. 1995 Feb; 80(2):226-9. View abstract
  130. Oberlander TF, Berde CB, Lam KH, Rappaport LA, Saul JP. Infants tolerate spinal anesthesia with minimal overall autonomic changes: analysis of heart rate variability in former premature infants undergoing hernia repair. Anesth Analg. 1995 Jan; 80(1):20-7. View abstract
  131. Suresh S, Ravilly S, Wohl ME, Berde CB. Anesthesia and perioperative care in cystic fibrosis. Anesth. Analg. 1995. View abstract
  132. Berde CB, Twum-Danso NAY, Wilder RT, Retik AJ. Epidural analgesia accelerates recovery following major pediatric urologic reconstructive surgery. Society for Pediatric Anesthesia/American Academy of Pediatrics. 1995. View abstract
  133. Wilder RT, Sholas M, Berde CB. L-nitroso-arginine methyl ester prevents tachyphylaxis to sciatic nerve blockade in a dose-dependent manner. Anesthesiology. 1995; 83:A808. View abstract
  134. Lee KC, Wilder RT, Smith RL, Berde CB. Thermal hyperalgesia accelerates and MK-801 prevents the development of tachyphylaxis to rat sciatic nerve blockade. Anesthesiology. 1994 Nov; 81(5):1284-93. View abstract
  135. Berde C. Epidural analgesia in children. Can J Anaesth. 1994 Jul; 41(7):555-60. View abstract
  136. Rusy LM, Houck CS, Ohlms LA, Jones DT, McGill TJ, Sullivan LJ, Berde CB. A double blind evaluation of ketorolac tromethamine versus acetaminophen in the pediatric tonsillectomy patient, effects on analgesia and bleeding. American Academy of Pediatrics, Section on Anesthesiology. 1994. View abstract
  137. Yee JD, Berde CB. Dextroamphetamine or methylphenidate as adjuvants to opioid analgesia for adolescents with cancer. J Pain Symptom Manage. 1994 Feb; 9(2):122-5. View abstract
  138. Kain ZN, O'Connor TZ, Berde CB. Management of tracheobronchial and esophageal foreign bodies in children: a survey study. J Clin Anesth. 1994 Jan-Feb; 6(1):28-32. View abstract
  139. Hu D, Hu R, Berde CB. Absolute volume predicts duration of sciatic blockade better than volume/kilogram in infant and adult rats. Anesthesiology. 1994; 81:A1375. View abstract
  140. Sang CN, Sethna NF, Sullivan L, Berde CB. Evaluation of epinephrine epidural test dose in children receiving isoflurane anesthesia. Anesthesiology. 1994; 81:A1344. View abstract
  141. Blank JW, Houck CS, McClain BC, Berde CB. Cephalad advancement of epidural catheters: radiographic correlation. Anesthesiology. 1994; 81:A1345. View abstract
  142. Olsson GL, Berde CB, Krane E, McGrath PA. Neuropathic pain in children. Abstracts of the 3rd International Pediatric Pain Symposium. 1994. View abstract
  143. Sang CN, Berde CV. The safety in pediatric regional analgesia study group: a multicenter study of safety and risk factors in pediatric regional analgesia. Anesthesiology. 1994; 81:A1386. View abstract
  144. Houck CS, McClain BC, Wilder RT, Sethna NF, Berde CB. The dose-response of epidural hydromorphone in children. Anesthesiology. 1994; 81:A1346. View abstract
  145. Sholas M, Wilder RT, Berde CB. Tachyphylaxis to sciatic blockade persists in spinalized rats. Anesthesiology. 1994; 81:A964. View abstract
  146. Hu R, Hu D, Berde CB. Epinephrine prolongs sciatic nerve block in infant but not adult rats. Anesthesiology. 1994; 81:A1356. View abstract
  147. Burrows FA, Berde CB. Optimal pain relief in infants and children. BMJ. 1993 Oct 02; 307(6908):815-6. View abstract
  148. Masters DB, Berde CB, Dutta S, Turek T, Langer R. Sustained local anesthetic release from bioerodible polymer matrices: a potential method for prolonged regional anesthesia. Pharm Res. 1993 Oct; 10(10):1527-32. View abstract
  149. Wilder RT, Berde CB, Griggs CT, Chickalingaiah R, Strichartz G. Chronic exposure to lidocaine does not alter flux through sodium channels in cultured neuronal cells. Reg Anesth. 1993 Sep-Oct; 18(5):283-9. View abstract
  150. Masters DB, Berde CB, Dutta SK, Griggs CT, Hu D, Kupsky W, Langer R. Prolonged regional nerve blockade by controlled release of local anesthetic from a biodegradable polymer matrix. Anesthesiology. 1993 Aug; 79(2):340-6. View abstract
  151. Kain ZN, Berde CB, Benjamin PK, Thompson JE. Performance of pediatric resuscitation bags assessed with an infant lung simulator. Anesth Analg. 1993 Aug; 77(2):261-4. View abstract
  152. Sethna NF, Berde CB. Venous air embolism during identification of the epidural space in children. Anesth Analg. 1993 May; 76(5):925-7. View abstract
  153. Berde CB. Toxicity of local anesthetics in infants and children. J Pediatr. 1993 May; 122(5 Pt 2):S14-20. View abstract
  154. Henderson K, Sethna NF, Berde CB. Continuous caudal anesthesia for inguinal hernia repair in former preterm infants. J Clin Anesth. 1993 Mar-Apr; 5(2):129-33. View abstract
  155. Truog RD, Berde CB. Pain, euthanasia, and anesthesiologists. Anesthesiology. 1993 Feb; 78(2):353-60. View abstract
  156. Houck CS, Berde C. Pain management in pediatrics. West J Med. 1993 Feb; 158(2):178-9. View abstract
  157. Perillo M, Sethna NF, Berde CB. Intravenous isoproterenol as a marker for epidural test-dosing in children. Anesth Analg. 1993 Jan; 76(1):178-81. View abstract
  158. Ly DQ, Berde CB, Hu D, Masters DB, Hu R. Comparison of injection and sustained release bupivicaine sciatic nerve blockade between adult and weaning rats. Anesthesiology. 1993; 79(3A):A908. View abstract
  159. Hu D, Hu R, Berde CB. Comparison of sciatic nerve blockade between infant and adult rats. Anesthesiology. 1993; 79(3A):A1137. View abstract
  160. Truog RD, Berde CB, Mitchell C, Grier HE. Barbiturates in the care of the terminally ill. N Engl J Med. 1992 Dec 03; 327(23):1678-82. View abstract
  161. Berde CB. Convulsions associated with pediatric regional anesthesia. Anesth Analg. 1992 Aug; 75(2):164-6. View abstract
  162. Wilder RT, Berde CB, Wolohan M, Vieyra MA, Masek BJ, Micheli LJ. Reflex sympathetic dystrophy in children. Clinical characteristics and follow-up of seventy patients. J Bone Joint Surg Am. 1992 Jul; 74(6):910-9. View abstract
  163. Masters DB, Griggs CT, Berde CB. High sensitivity quantification of RNA from gels and autoradiograms with affordable optical scanning. Biotechniques. 1992 Jun; 12(6):902-6, 908-11. View abstract
  164. Irazuzta JE, Berde CB, Sethna NF. Laser Doppler measurements of skin blood flow before, during, and after lumbar sympathetic blockade in children and young adults with reflex sympathetic dystrophy syndrome. J Clin Monit. 1992 Jan; 8(1):16-9. View abstract
  165. Sethna NF, Berde CB. Pediatric regional anesthesia equipment. Int Anesthesiol Clin. 1992; 30(3):163-76. View abstract
  166. Kain ZN, Berde CB, Benjamin PK, Thompson JE. Performance of pediatric resuscitation bags assessed with an infant lung simulator. Anesthesiology. 1992; 77:A509. View abstract
  167. Wilder RT, Berde CB, Troshynski TJ, Cahill CA, Sethna NF. Patient-controlled analgesia in children and adolescents: safety and outcome amoung 1,589 patients. Anesthesiology. 1992; 77:A1187. View abstract
  168. Sethna NF, Berde CB, Wilder RT, Strafford MA. The risk of infection from pediatric epidural analgesia is low. Anesthesiology. 1992; 77:A1158. View abstract
  169. Sievers TD, Yee JD, Foley ME, Blanding PJ, Berde CB. Midazolam for conscious sedation during pediatric oncology procedures: safety and recovery parameters. Pediatrics. 1991 Dec; 88(6):1172-9. View abstract
  170. Sethna NF, Berde CB. Continuous subarachnoid analgesia in two adolescents with severe scoliosis and impaired pulmonary function. Reg Anesth. 1991 Nov-Dec; 16(6):333-6. View abstract
  171. Berde CB, Beyer JE, Bournaki MC, Levin CR, Sethna NF. Comparison of morphine and methadone for prevention of postoperative pain in 3- to 7-year-old children. J Pediatr. 1991 Jul; 119(1 Pt 1):136-41. View abstract
  172. Desparmet JF, Berde CB, Schwartz DC, Lunn RJ, Hershenson MB. Efficacy of adrenaline, lignocaine-adrenaline and isoprenaline as a test dose in halothane-anaesthetized lambs. Eur J Anaesthesiol. 1991 Mar; 8(2):123-8. View abstract
  173. Berde CB, Lehn BM, Yee JD, Sethna NF, Russo D. Patient-controlled analgesia in children and adolescents: a randomized, prospective comparison with intramuscular administration of morphine for postoperative analgesia. J Pediatr. 1991 Mar; 118(3):460-6. View abstract
  174. Vieyra MA, Masek BJ, Berde CB, Allen GA. Children's pain and family functioning: a comparative analysis. J. Pain and Symptom Management. 1991; 6:146. View abstract
  175. Yee JD, Berde CB. Methylphenidate or dextraamphetamine as adjuvants in opioid analgesia. Journal of Pain and Symptom Management. 1991; 6:162. View abstract
  176. Masters DB, Dutta S, Langer R, Berde CB. Porlonged sciatic nerve blockade using sustained release of bupivicaine from a biodegradable polymer matrix. Anesthesiology. 1991; 75:A765. View abstract
  177. Cahill C, Gondek E, Stafford MA, Sethna NF, Berde CB. Implementation of a PCA program. Journal of Pain and Symptom Management. 1991; 6:187. View abstract
  178. Stafford MA, Cahill C, Schwartz T, Yee JD, Sethna NF, Berde CB. Recognition and treatment of pain in pediatric patients with AIDS. Journal of Pain and Symptom Management. 1991; 6:162. View abstract
  179. Beyer JE, Berde CB, Bournaki MC. Memories of pain in three- to seven-year-old children. Journal of Pain and Symptom Management. 1991; 6:174. View abstract
  180. Henderson KH, Sethna NF, Berde CB. Continuous caudal anesthesia with 2-chloroprocaine for premature infants undergoing inguinal hernia repair. Anesthesiology. 1991; 75:A693. View abstract
  181. Sethna NF, Stafford MA, Berde CB. Experience with 852 epidural infusions in a children's hospital. Journal of Pain and Symptom Management. 1991; 6:164. View abstract
  182. Wilder RT, Berde CB, Wolohan M, Micheli LM, Vieyra MA. Reflex sympathetic dystrophy in children and adolescents: follow-up of 70 patients adn development of a treatment algorithm. Anesthesiology. 1991; 75:A916. View abstract
  183. Beyer JE, McGrath PJ, Berde CB. Discordance between self-report and behavioral pain measures in children aged 3-7 years after surgery. J Pain Symptom Manage. 1990 Dec; 5(6):350-6. View abstract
  184. Berde CB, Sethna NF, Fisher DE, Kahn CH, Chandler P, Grier HE. Celiac plexus blockade for a 3-year-old boy with hepatoblastoma and refractory pain. Pediatrics. 1990 Nov; 86(5):779-81. View abstract
  185. Berde C, Ablin A, Glazer J, Miser A, Shapiro B, Weisman S, Zeltzer P. American Academy of Pediatrics Report of the Subcommittee on Disease-Related Pain in Childhood Cancer. Pediatrics. 1990 Nov; 86(5 Pt 2):818-25. View abstract
  186. Berde CB, Sethna NF, Conrad LS, Hershenson MB, Shillito J. Subarachnoid bupivacaine analgesia for seven months for a patient with a spinal cord tumor. Anesthesiology. 1990 Jun; 72(6):1094-6. View abstract
  187. Berde CB, Yee JD, Lehn BM, Moore LJ, Sethna NF. Patient-controlled analgesia in children and adolescents: a randomized comparison with intramuscular morphine. Anesthesiology. 1990; 73:A1102. View abstract
  188. Holzman RS, Pascucci RV, Sethna NF, Berde CB. Hypotension, flushing and bronchospasm in myelodysplasia patients undergoing surgery. Section on Anesthesiology, American Academy of Pediatrics. 1990; Spring. View abstract
  189. Berde CB, Sethna NF, Yemen TA, Pullerits J, Miler V. Continuous epidural bupivacaine-fentanyl infusions in children following ureteral reimplantation. Anesthesiology. 1990; 73:A775. View abstract
  190. Perillo M, Sethna NF, Berde CB. Isoproterenol for test dosing in pediatric regional blockade. Anesthesiology. 1990; 73:A1127. View abstract
  191. Berde CB, Masters DB, Dutta S, Turek T, Langer R. Sustained release of dibucaine from a biodegradable polymer matrix: a potential method for prolonged neural blockade. Anesthesiology. 1990; 73:A776. View abstract
  192. Berde CB. Regional analgesia in the management of chronic pain in childhood. J Pain Symptom Manage. 1989 Dec; 4(4):232-7. View abstract
  193. Anderson CT, Berde CB, Sethna NF, Pribaz JJ. Meningococcal purpura fulminans: treatment of vascular insufficiency in a 2-yr-old child with lumbar epidural sympathetic blockade. Anesthesiology. 1989 Sep; 71(3):463-4. View abstract
  194. Shannon M, Berde CB. Pharmacologic management of pain in children and adolescents. Pediatr Clin North Am. 1989 Aug; 36(4):855-71. View abstract
  195. Berde CB. Pediatric postoperative pain management. Pediatr Clin North Am. 1989 Aug; 36(4):921-40. View abstract
  196. Chang HM, Berde CB, Holz GG, Steward GF, Kream RM. Sufentanil, morphine, met-enkephalin, and kappa-agonist (U-50,488H) inhibit substance P release from primary sensory neurons: a model for presynaptic spinal opioid actions. Anesthesiology. 1989 Apr; 70(4):672-7. View abstract
  197. Berde CB, Fischel N, Filardi JP, Coe CS, Grier HE, Bernstein SC. Caudal epidural morphine analgesia for an infant with advanced neuroblastoma: report of a case. Pain. 1989 Feb; 36(2):219-23. View abstract
  198. Scuderi G, Sanders DP, Brustowicz RM, Berde CB, Colin A, Allen J, Healy GB, Hall JE. Postoperative lordoscoliosis causing extrinsic compression of the right main stem bronchus and respiratory insufficiency. A case report. Spine (Phila Pa 1976). 1989 Jan; 14(1):110-4. View abstract
  199. Berde CB, Sethna NF, Levin L, Retik A, Millis M, Lillehei C, Micheli L. Regional analgesia on pediatric medical and surgical wards. Intensive Care Med. 1989; 15 Suppl 1:S40-3. View abstract
  200. Berde C, Sethna NF, Masek B, Fosburg M, Rocklin S. Pediatric pain clinics: recommendations for their development. Pediatrician. 1989; 16(1-2):94-102. View abstract
  201. Holzman R, Sethna NF, Berde CB. Spinal vs. general anesthesia in infants undergoing hernia repair. Section on Anesthesiology, American Academy of Pediatrics. 1989. View abstract
  202. Vieyra M, Masek BJ, Berde CB. Reflex sympathetic dystrophy in children and adolescents. Society for Behavioral Medicine. 1989. View abstract
  203. Lunn RJ, Berde CB, Sethna NF, Johnson C, Gonzalez M. Stellate ganglion blockade in children and adolescents. Anesthesiology. 1989; 71:A1023. View abstract
  204. Desparmet J, Berde CB, Schwartz D, Lunn RJ, Hershenson M. Epidural test dosing in halothane-anesthesized lambs. Anesthesiology. 1989; 72:A1022. View abstract
  205. Berde CB, Warfield CA. Pediatric pain management. Hosp Pract (Off Ed). 1988 May 30; 23(5A):83-4, 89, 93-4 passim. View abstract
  206. Colin AA, Allen JL, Berde CB, Griscom NT, Hall JE, Young LW. Radiological case of the month. Bronchial compression and ventilatory dysfunction in scoliosis. Am J Dis Child. 1988 May; 142(5):545-6. View abstract
  207. Berde CB, Holzman RS, Sethna NF, Dickerson RB, Brustowicz RM. A comparison of methadone and morphine for postoperative analgesia in children and adolescents. Anesthesiology. 1988; 69:A768. View abstract
  208. Berde CB, Sethna NF, Micheli LJ. A technique for continuous lumbar sympathetic blockade for severe reflex sympathetic dystrophy in children and adolescents. Anesth Analg. 1988; 67:S4. View abstract
  209. Berde CB, Lacouture PG, Masek BJ, Sethna NF. Initial experience with a multidiscplinary pediatric pain treatment service. Pain. 1987; Supplement 4:S99. View abstract
  210. Berde CB, Sethna NF, Holzman RS, Reidy P, Gondek E. Pharmacokinetics of methadone in children and adolescents in the perioperative period. Anesthesiology. 1987; 67:A519. View abstract
  211. Berde CB, Sethna NF. Regional anesthetic approaches to post-operative pain in children and adolescents. Intensive Care Med. 1987; 13:460. View abstract
  212. Chang HM, Berde CB, Holz GG, Steward GF, Kream RM. Opioids inhibit substance P release from cultured dorsal root ganglia: a model for spinal narcotic action. Anesthesiology. 1987; 67:A388. View abstract
  213. Badwey JA, Curnutte JT, Robinson JM, Berde CB, Karnovsky MJ, Karnovsky ML. Effects of free fatty acids on release of superoxide and on change of shape by human neutrophils. Reversibility by albumin. J Biol Chem. 1984 Jun 25; 259(12):7870-7. View abstract
  214. Simmons CF, Winter HS, Berde C, Schrater F, Humphrey GB, Rosen FS, Beaver PC, Weller PF. Zoonotic filariasis with lymphedema in an immunodeficient infant. N Engl J Med. 1984 May 10; 310(19):1243-5. View abstract
  215. Berde CB, Benitz WE, Rasmussen LF, Kerner JA, Johnson JD, Wennberg RP. Bilirubin binding in the plasma of newborns: critical evaluation of a fluorescence quenching method and comparison to the peroxidase method. Pediatr Res. 1984 Apr; 18(4):349-54. View abstract
  216. Karnovsky ML, Badwey JA, Curnutte JT, Robinson JM, Berde CB, Karnovsky MJ. Some functional effects of physical changes in the membranes of white cells. Kroc Found Ser. 1984; 16:111-27. View abstract
  217. Karnovsky ML, Badwey JA, Curnutte JT, Robinson JM, Berde CB, Karnovsky MJ. The excitable membrane of phagocytic leukocytes. Prog Clin Biol Res. 1984; 164:347-54. View abstract
  218. Berde C, Willis DC, Sandberg EC. Pregnancy in women with pseudoxanthoma elasticum. Obstet Gynecol Surv. 1983 Jun; 38(6):339-44. View abstract
  219. Coolbear KP, Berde CB, Keough KM. Gel to liquid-crystalline phase transitions of aqueous dispersions of polyunsaturated mixed-acid phosphatidylcholines. Biochemistry. 1983 Mar 15; 22(6):1466-73. View abstract
  220. Badwey JA, Curnutte JT, Berde CB, Karnovsky ML. Cytochalasin E diminishes the lag phase in the release of superoxide by human neutrophils. Biochem Biophys Res Commun. 1982 May 14; 106(1):170-4. View abstract
  221. Berde CB, Coolbear KP, Keough KMW. Phase transitions of dispersions of polyunsaturated mixed acid phosphatidyl cholines: calorimetric measurements and a statistical-mechanical description. Mackinac Conference on Artificial Surfactant Proceedings. 1982. View abstract
  222. Kerner JA, Cassani C, Hurwitz R, Berde CB. Monitoring intravenous fat emulsions in neonates with the fatty acid/serum albumin molar ratio. JPEN J Parenter Enteral Nutr. 1981 Nov-Dec; 5(6):517-8. View abstract
  223. Berde CB, Andersen HC, Hudson BS. A theory of the effects of head-group structure and chain unsaturation on the chain melting transition of phospholipid dispersions. Biochemistry. 1980 Sep 02; 19(18):4279-93. View abstract
  224. Berde CB, Kerner JA, Johnson JD. Use of the conjugated polyene fatty acid, parinaric acid, in assaying fatty acids in serum or plasma. Clin Chem. 1980 Jul; 26(8):1173-7. View abstract
  225. Berde CB, Nagai M, Deutsch HF. Human alpha-fetoprotein. Fluorescence studies on binding and proximity relationships for fatty acids and bilirubin. J Biol Chem. 1979 Dec 25; 254(24):12609-14. View abstract
  226. Berde CB, Hudson BS, Simoni RD, Sklar LA. Human serum albumin. Spectroscopic studies of binding and proximity relationships for fatty acids and bilirubin. J Biol Chem. 1979 Jan 25; 254(2):391-400. View abstract
  227. Berde CB, Rasmussen F, Benitz W, Kerner JA, Johnson JD, Wennberg R. Binding of bilirubin and fatty acids in the sera of neonates. Clin Res. 1979; 27:134A. View abstract
  228. Daan S, Berde C. Two coupled oscillators: simulations of the circadian pacemaker in mammalian activity rhythms. J Theor Biol. 1978 Feb 06; 70(3):297-313. View abstract
  229. Berde CB, Kerner JA, Johnson JD. A free fatty acid binding index for serum. Pediatr Res. 1978; 12:502. View abstract
  230. Berde CB, Heller RA, Simoni RD. Activation of purified 3-hydroxy-3-methylglutaryl-CoA reductase by phospholipids. Biochim Biophys Acta. 1977 Jul 20; 488(1):112-20. View abstract
  231. Berde C. A population-family planning resource center: a community educational service. Fam Plann Resume. 1977; 1(1):142-3. View abstract
  232. Berde C. Nonmonotonic transients and some mathematical models of circadian rhythms. J Theor Biol. 1976 Feb; 56(2):435-41. View abstract