The Division of Immunology has a long track record of cutting edge research in allergic and immunological mechanisms and is recognized world-wide for work on IgE regulation,
Current areas of basic research include:-
Pathogenesis of atopic dermatitis
- Wiskott Aldrich Syndrome protein (WASP) and associated molecules
- Signal transduction by the T cell receptor, the role of SLP-76
- Regulation of IgE production
- Roles of IgE in allergic pathogenesis and parasite immunity
- TRAF functions in TNF receptor family signaling
Ongoing clinical projects include:
- The evaluation of immunomodulators in asthma and atopic dermatitis.
- A study of the efficacy of purified C1 esterase inhibitor in hereditary angioneurotic edema.
- The evaluation of intravenous gammaglobulin
treatment of patients with antibody deficiency disorders.
- Studies of the use of anti_IgE in the treatment of asthma and atopic dermatitis.
Featured researchers in the Division of Immunology hold faculty appointments at Harvard Medical School.
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Immunology
