Publications

He X, Saint-Jeannet J-P, Nathans J, Wang Y, Dawid IB, Varmus H E. A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science 1997; 275:1652-1654.

Finch PW, He X, Kelley MJ, Uren A, Schaudies P, Popescu NC, Rudikoff S, Aaronson SA, Varmus HE, Rubin J S. Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. PNAS USA 1997; 94:6770-6775.

Saint-Jeannet J-P, He X, Varmus HE, Dawid IB. Regulation of dorsal fate in the neuraxis by Wnt-1 and Wnt-3a. PNAS USA 1997; 94:13713-13718.

Zhang Z, Hartmann H, Do VM, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Sommer B, van de Wetering M, Clevers H, Saftig P, De Strooper B, He X, Yankner BA. Destabilization of beta-catenin by Presenilin-1 mutations increases neuronal vulnerability to apoptosis. Nature 1998; 395:698-702.

Liu C, Kato Y, Zhang Z, Do VM, Yankner BA, He X. Beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation. PNAS USA 1999; 96:6273-6278.

Kato Y, Shi Y, He X. Neuralization of the Xenopus embryo by inhibition of p300/CBP function. J Neurosci 1999; 19:9346-9373.

Semenov MV, Tamai K, Brott BK, Kuhl M, Sokol S, He X. The Wnt antagonist Dickkopf 1 is a ligand for low density lipoprotein receptor related proteins. Curr Biol 2001;26:951-961.

Liu C, Y. L, Semenov M, Baeg G-H, Han C, Tan Y, Zhang Z, Lin X, He X. Control of beta-catenin phosphorylation-degradation by a dual-kinase mechanism. Cell 2002;108:837-847.

Zhang Y, Qiu W-J, Chan SC, Han JH, He X, Lin SC. Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways. J Biol Chem 2002;277:17706-17712.

Luo ZG, Wang Q, Zhou J, Wang J, Luo ZJ, Liu M, He X, Wynshaw-Boris A, Xiong WC, Lu G, Mei L. Regulation of AChR Clustering by Dishevelled Interacting with MuSK and PAK1. Neuron 2002;35:489-505.

Kato Y, Habas R, Katsuyama Y, Naar A, He X. A component of the ARC/Mediator complex required for TGF-beta/Nodal signaling. Nature 2002;418:641-646.

Capelluto DGS, Kutateladze TG, Habas R, Finkielstein CV, He X, Overduin M. DIX domain targets dishevelled to actin stress fibers and vesicular membranes. Nature 2002;419:726-729.

Widlund H, Horstmann M, Price E, Cui J, Lessnick S, Wu M, He X, Fisher D. Beta-catenin induced melanoma growth requires the downstream target MITF. J Cell Biol 2002;158:1079-1087.

Habas R, Dawid I, He X. Co-activation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. Genes Dev 2003;17:295-309.

Semenov M, He X. Secreted extracellular Wnt modulators. In: Kuhl M, editor. Wnt Signaling in Development. Georgetown, Texas: Landes Biosciences; 2003;16-35.

He X. A Wnt -Wnt situation (meeting review). Dev Cell 2003;4:791-797.

He X, Bazan JF, McDermott G, Park JB, K. W, He Z, Garcia KC. Structure of a soluble Nogo receptor ectodomain: a recognition module implicated in myelin inhibition. Neuron 2003;38:177-185.

He X, Semenov M, Tamai K, Zeng X. LDL receptor-related proteins 5 and 6 in Wnt/{beta}-catenin signaling: Arrows point the way. Development 2004;131(8):1663-1677.

Tamai K, Zeng X, Liu C, Zhang X, Harada Y, Chang Z, He X. A mechanism for Wnt coreceptor activation. Mol Cell 2004;13(1):149-56.

Wu G, Liu C, He X. Ozz; a new name on the long list of beta-catenin's nemeses. Mol Cell 2004;13(4):451-3.

Ossipova1 O, He X, Green J. Molecular cloning and developmental expression of Par-1/MARK homologues XPar-1A and XPar-1B from Xenopus laevis. Mech Dev 2004, in press.

See Dr. He's publications via PubMed