Publications

Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law T, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, Kingsley PD, Palis J, Fleming MD, Andrews NC,Zon LI. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature, 2000; 403:776-781.

Trenor III, CC., Campagna DR, Sellers VM, Andrews NC, Fleming MD. The molecular defect in hypotransferrinemic mice.Blood, 2000; 96:1113-1118.

Canonne-Hergaux F, Fleming MD, Levy J., Gauthier S, Ralph T, Picard V, Andrews NC, Gros P. The NRAMP2/DMT1 iron transporter is induced in the duodenum of microcytic anemia (mk) mice but is not properly targeted to the intestinal brush border. Blood, 2000; 96:3964-70.

Elenbaas B, Spirio L, Koerner F, Fleming MD, Zimonjic DB, Donaher JL, Popescu NC, Hahn WC, Weinberg RA. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev, 2001; 15(1):50-65.

Canonne-Hergaux, F, Levy JE, Fleming MD, Montross LK, Andrews NC, and Gros P. Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders. Blood, 2001; 97:1138-1140.

Fleming MD, Campagna DR, Haslett JN, Trenor CC, and Andrews NC. A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematologic and skeletal phenotype of flexed-tail (f) mice. Genes Dev, 2001; 15:652-657.

Bennett CM., Kanki JP, Rhodes J, Liu TX, Paw BH, Kieran MW, Langenau DM, Delahaye-Brown A, Zon LI, Fleming MD, Look AT. Myelopoiesis in the zebrafish, Danio rerio. Blood, 2001; 98(3):643-651.

Ghaffari S, Kitidis C, Fleming MD, Neubauer H, Pfeffer K, and Lodish HF. Erythropoiesis in the absence of Janus-Kinase 2: BCR-ABL induces red cell formation in JAK2-/- hematopoietic progenitors. Blood, 2001; 98(10):2948-2957.

Socolovsky M, Nam H, Fleming MD, Haase VH, Brugnara C, Lodish HF. Ineffective erythropoiesis in Stat5a(-/-) 5b(-/-) mice due to decreased survival of early erythroblasts. Blood, 2001; 98(12):3261-73.

Han AP, Yu C, Lu L, Fujiwara Y, Browne C, Chin G, Fleming M, Leboulch P, Orkin SH, Chen JJ. Heme-regulated eIF2 kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency. EMBO J, 2001; 20(23):6909-18.

Fleming JC, Steinkamp MP, Kawatsuji R, Tartaglini E, Pinkus JL, Pinkus GS, Fleming MD, Neufeld EJ. Characterization of a murine high-affinity thiamine transporter, Slc19a2. Mol Genet Metab, 2001 2001; 4(1-2):273-80.

Domchek SM, Hecht JL, Fleming MD, Pinkus GS, Canellos GP. Lymphomas of the breast. Cancer, 2002; 94(1):6-13.

Lundberg AS, Randell SH, Stewart SA, Elenbaas B, Hartwell KA, Brooks MW, Fleming MD, Olsen JC, Miller SW, Weinberg RA, Hahn WC. Immortalization and transformation of primary human airway epithelial cells by gene transfer. Oncogene, 2002; 21(29):4577-86.

Stewart SA, Hahn WC, O'Connor BF, Banner EN, Lundberg AS, Modha P, Mizuno H, Brooks MW, Fleming M, Zimonjic DB, Popescu NC, Weinberg RA. Telomerase contributes to tumorigenesis by a telomere length-independent mechanism. PNAS, 2002; 99(20):12606-11.

Fleming, MD. The genetics of inherited sideroblastic anemias. Semin Hematol, 2002; 39(4):270-81.

Weinstein DA, Roy CN, Fleming MD, Loda MF, Wolfsdorf JI, Andrews NC. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood, 2002; 100(10):3776-81.

Roberts CW, Leroux MM, Fleming MD, Orkin SH. Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5. Cancer, Cell, 2002; 2(5):415-25.

Fleming JC, Tartaglini E, Kawatsuji R, Yao D, Fujiwara Y, Bednarski JJ, Fleming MD, and Neufeld E. Male infertility and thiamine-dependent erythroid hypoplasia in mice lacking thiamine transporter Slc19a2. Mol Genet Metab, 2003; 80(1-2):234-41.


See Dr. Fleming's publications via PubMed