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Publications
Donovan
A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer
A, Barut B, Zapata A, Law T, Brugnara C, Lux SE, Pinkus GS, Pinkus JL,
Kingsley PD, Palis J, Fleming MD, Andrews NC,Zon LI. Positional cloning
of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.
Nature, 2000; 403:776-781.
Trenor III, CC., Campagna DR, Sellers VM, Andrews NC, Fleming MD. The
molecular defect in hypotransferrinemic mice.Blood, 2000; 96:1113-1118.
Canonne-Hergaux F, Fleming MD, Levy J., Gauthier S, Ralph T, Picard
V, Andrews NC, Gros P. The NRAMP2/DMT1 iron transporter is induced in
the duodenum of microcytic anemia (mk) mice but is not properly targeted
to the intestinal brush border. Blood, 2000; 96:3964-70.
Elenbaas B, Spirio L, Koerner F, Fleming MD, Zimonjic DB, Donaher JL,
Popescu NC, Hahn WC, Weinberg RA. Human breast cancer cells generated
by oncogenic transformation of primary mammary epithelial cells. Genes
Dev, 2001; 15(1):50-65.
Canonne-Hergaux, F, Levy JE, Fleming MD, Montross LK, Andrews NC, and
Gros P. Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice
with genetic iron overload disorders. Blood, 2001; 97:1138-1140.
Fleming MD, Campagna DR, Haslett JN, Trenor CC, and Andrews NC. A mutation
in a mitochondrial transmembrane protein is responsible for the pleiotropic
hematologic and skeletal phenotype of flexed-tail (f) mice. Genes
Dev, 2001; 15:652-657.
Bennett CM., Kanki JP, Rhodes J, Liu TX, Paw BH, Kieran MW, Langenau
DM, Delahaye-Brown A, Zon LI, Fleming MD, Look AT. Myelopoiesis in the
zebrafish, Danio rerio. Blood, 2001; 98(3):643-651.
Ghaffari S, Kitidis C, Fleming MD, Neubauer H, Pfeffer K, and Lodish
HF. Erythropoiesis in the absence of Janus-Kinase 2: BCR-ABL induces
red cell formation in JAK2-/- hematopoietic progenitors. Blood,
2001; 98(10):2948-2957.
Socolovsky M, Nam H, Fleming MD, Haase VH, Brugnara C, Lodish HF. Ineffective
erythropoiesis in Stat5a(-/-) 5b(-/-) mice due to decreased survival
of early erythroblasts. Blood, 2001; 98(12):3261-73.
Han AP, Yu C, Lu L, Fujiwara Y, Browne C, Chin G, Fleming M, Leboulch
P, Orkin SH, Chen JJ. Heme-regulated eIF2 kinase (HRI) is required for
translational regulation and survival of erythroid precursors in iron
deficiency. EMBO J, 2001; 20(23):6909-18.
Fleming JC, Steinkamp MP, Kawatsuji R, Tartaglini E, Pinkus JL, Pinkus
GS, Fleming MD, Neufeld EJ. Characterization of a murine high-affinity
thiamine transporter, Slc19a2. Mol Genet Metab, 2001 2001; 4(1-2):273-80.
Domchek SM, Hecht JL, Fleming MD, Pinkus GS, Canellos GP. Lymphomas
of the breast. Cancer, 2002; 94(1):6-13.
Lundberg AS, Randell SH, Stewart SA, Elenbaas B, Hartwell KA, Brooks
MW, Fleming MD, Olsen JC, Miller SW, Weinberg RA, Hahn WC. Immortalization
and transformation of primary human airway epithelial cells by gene
transfer. Oncogene, 2002; 21(29):4577-86.
Stewart SA, Hahn WC, O'Connor BF, Banner EN, Lundberg AS, Modha P, Mizuno
H, Brooks MW, Fleming M, Zimonjic DB, Popescu NC, Weinberg RA. Telomerase
contributes to tumorigenesis by a telomere length-independent mechanism.
PNAS, 2002; 99(20):12606-11.
Fleming, MD. The genetics of inherited sideroblastic anemias. Semin
Hematol, 2002; 39(4):270-81.
Weinstein DA, Roy CN, Fleming MD, Loda MF, Wolfsdorf JI, Andrews NC.
Inappropriate expression of hepcidin is associated with iron refractory
anemia: implications for the anemia of chronic disease. Blood,
2002; 100(10):3776-81.
Roberts CW, Leroux MM, Fleming MD, Orkin SH. Highly penetrant, rapid
tumorigenesis through conditional inversion of the tumor suppressor
gene Snf5. Cancer, Cell, 2002; 2(5):415-25.
Fleming JC, Tartaglini E, Kawatsuji R, Yao D, Fujiwara Y, Bednarski
JJ, Fleming MD, and Neufeld E. Male infertility and thiamine-dependent
erythroid hypoplasia in mice lacking thiamine transporter Slc19a2. Mol
Genet Metab, 2003; 80(1-2):234-41.
See
Dr. Fleming's publications via PubMed
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