Current Environment:

 

  • Kaufman CK, Mosimann C, Fan ZP, Yang S, Thomas AJ, Ablain J, Tan JL, Fogley RD, van Rooijen E, Hagedorn EJ, Ciarlo C, White RM, Matos DA, Puller AC, Santoriello C, Liao EC, Young RA, Zon LI. A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation. Science. 2016 Jan 29;351(6272):aad2197. PMID: 26823433
  • Tamplin OJ, Durand EM, Carr LA, Childs SJ, Hagedorn EJ, Li P, Yzaguirre AD, Speck NA, Zon LI. Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche. Cell. 2015 Jan 15;160(1-2):241-52. PMID:25594182
  • Li P, Lahvic JL, Binder V, Pugach EK, Riley EB, Tamplin OJ, Panigrahy D, Bowman TV, Barrett FG, Heffner GC, McKinney-Freeman S, Schlaeger TM, Daley GQ, Zeldin DC, Zon LI. Epoxyeicosatrienoic acids enhance hematopoietic stem and progenitor cell engraftment. Nature. 2015 Jul 22;523(7561):468-71. PMID: 26201599
  • Xu C, Tabebordbar M, Lovino S, Ciarlo C, Liu J, Castiglioni A, Price E, Kahn RC, Wagers AJ, and Zon LI.  A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species.  Cell, 2013, Nov 7;155(4):909-21. PMCID: PMC3902670
  • Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferre F, Bourque C, Burke C, Turner L, Uong A, Johnson LA, Beroukhim R, Mermel CH, Loda M, Slimane A-S-A, Garraway L, Young RA, and Zon LI.  The SETDB1 histone methyltransferase is recurrently amplified in and accelerates melanoma.  Nature, 2011, Mar 24:471, 513-517. PMCID: PMC3348545
  • White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahls PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, Granter S, Young RA, Morrison S, Wheeler GN, and Zon LI.  DHODH modulates transcriptional elongation in the neural crest and melanoma.  Nature. 2011, Mar 24:471, 518-522. PMCID:PMC3759979
  • Trompouki E, Bowman TV, Lawton LN, Fan ZP, Wu D-C, DiBiase A, Martin CS, Cech JN, Sessa AK, Leblanc JL, Li P, Durand E, Mosimann C, Heffner GC, Daley GQ, Paulson RF, Young RA and Zon LI.  Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration.  Cell, 2011, October 28:147 (3);577-589. PMCID: PMC3219441
  • Bai X, Kim J, Yang Z, Jurynec M, Lee J, LeBlanc J, Sessa A, Jiang H, Grunwald DJ, Lin S, Orkin SH, Zon LI.  TIF1γ controls erythroid cell fate by regulating transcriptional elongation. Cell, 2010, Jul 9;142(1):133-143. PMCID: PMC3072682
  • Goessling W, North TE, Loewer S, Lord AM, Lee S, Stick-Cooper CL, Weidinger G, Puder M, Daley GQ, Moon RT, and Zon LI.  Genetic interaction of PGE2 and wnt signaling regulates developmental specification of stem cells and regeneration.  Cell, 2009 Mar 20;136(6):1136-46. PMCID:PMC2692708
  • North TE, Goessling W, Peeters M, Li P, Ceol C, Lord AM, Weber GJ, Harris J, Cutting CC, Huang P, Dzierzak E, and Zon LI.  Hematopoietic stem cell development is dependent on blood flow. Cell, 2009, May 15;137(4):736-748. PMCID:PMC2722870
  • North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber G, Bowman TV, Jang IH, Grosser T, FitzGerald GA, Daley GQ, Orkin SH, and Zon LI.  Prostaglandin E2 regulates vertebrate hematopoietic stem cell homeostasis.  Nature, 2007, Jun 21;447(7147):1007-11. PMCID: PMC2775137
  • Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, Kingsley PD, Palis J, Fleming MD, Andrews NC, and Zon LI.  Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.  Nature, 2000.