Oettgen Laboratory | Current Research Projects

·      Influence of IgE on mast cell homeostasis in the intestine

·      The function of food-specific IgG antibodies and signaling, via FcyRIIb, on inhibition both in immediate hypersensitivity reactions mediated by mast cells and basophils as well as on APC:T cell interactions in the intestine and the emerging Th2/Treg balance

·      FcyRIIb signaling pathways in mast cells

·      Cell intrinsic differences in basophil sensitivity to allergens as a basis of the widely variable sensitivity of patients with food allergen-specific IgE to food ingestion