Berde Lab | Meet the Team


Principal Investigator 

Charles B. Berde, MD, PhD

Charles Berde

Dr. Berde is the Sara Page Mayo Chair in Pediatric Pain Medicine, Chief of the Division of Pain Medicine at Boston Children's Hospital, and Professor of Anaesthesia (Pediatrics) at Harvard Medical School. He completed an MD and PhD (Biophysics) at Stanford University; his Residency in Pediatrics, at Boston Children's Hospital; Residency in Anesthesiology, at Massachusetts General Hospital; and Fellowship in Pediatric Anesthesiology, at Boston Children's Hospital.

Dr. Berde directs the Pain Treatment Service at Boston Children's Hospital, the first and most clinically active acute and chronic pain management program for children in the world. Dr. Berde’s translational research concerns local anesthetic mechanisms and the development of novel prolonged duration local anesthetics that are now in clinical trials. His clinical research concerns clinical pharmacology of analgesics and local anesthetics in children, clinical outcomes of treatment of neuropathic pain and cancer pain in children, functional brain imaging of children with neuropathic pain, and brain dynamic studies in children during general anesthesia.  Translation research on novel prolonged duration local anesthetics has progressed for our laboratory to clinical trials. Dr. Berde is the author of over 130 original peer reviewed articles and over 100 chapters and reviews. He was profiled as one of Time Magazine's "Heroes in Medicine" in 1997. He has received several awards and honors for his pioneering work in pediatric pain relief, including the 2003 Scientific Achievement Award of the Reflex Sympathetic Dystrophy Syndrome Association, and the 2015 IASP Special Interest Group in Pediatric Pain Distinguished Career Award.


Laura Cornelissen, PhD [Email] [Publications] [ResearchGate]

Laura Cornelissen

Dr. Cornelissen received her PhD in Neuroscience from University College London, UK.  Her research interests are in the neurophysiology of acute and chronic pain, analgesia and general anesthesia in infants, children and adolescents.

Postdoctoral Research Fellow

Joe Kossowsky, PhD [Email] [Publications] [ResearchGate]

Joe Kossowsky

Dr. Kossowsky received his PhD in Clinical Psychology and Neuroscience from University of Basel, Switzerland. His current research is focused on post-operative pain, placebo effects, and clinical trials design. Dr. Kossowsky completed his psychotherapy training and worked as a psychotherapist with children and adolescents at the psychotherapeutic outpatient clinic at the University of Basel.

Research Fellow

Carolina Donado, MD [Email] [Publications]

Carolina Donado

Dr. Donado earned her medical degree at Universidad de los Andes in Bogotá, Colombia in 2011. Her main focus in pain research has been in outcome measures involving acute and chronic pain management. Her main interest is in pediatric care and pain management.


Kimberly Lobo, MS, MPH [Email] [Publications] [ResearchGate]

Kimberly LoboKimberly Lobo earned her Master in Public Health degree in Epidemiology from Boston University. She also has a Master of Science degree in Biochemistry from University of Mumbai, India. Her research interests include the application of epidemiologic and statistical methods for clinical trials and outcomes research, study design, survey methodology, health disparities, and longitudinal data analysis.

Research Assistant

Uday HeadshotUday Agrawal, BS [Email] [Publications]

Uday Agrawal received his BS in Applied Mathematics and Neuroscience from Brown University. He is currently an MD student enrolled on the Harvard-MIT Health Sciences Technology program. His research interests include multimodal signal processing.

Genevieve Spagnuolo, MS [Email] [Publications]

Genevieve Spagnuolo received her MS in Biomedical Science from Tufts University. Her research interests include chronic pain treatment in the pediatric population.


Mirissa Price

Mirissa is a DMD student (class of 2019) at Harvard Dental School. Mirissa is working on an oral health project with our dentistry colleagues, Drs. Ng and Chase, using teledentistry in the pediatric chronic pain population.

Dafni Frohman 

Dafni is studying for a BS in Biologicial Sciences (class of 2019) at Tufts University. Dafni is working on a series of chronic pain projects within the Pain Treatment Service.

Ioannis Pappas, MSc 

Ioannis is a PhD student from the University of Cambridge (UK). Ioannis is working on developing connectivity analysis tools to further understand the functionalactivity of brain regions involved in anesthesia-induced unconsciousness.