1990

19. Rivera VM, Sheng M, Greenberg ME. The inner core of the serum response element mediates both the rapid induction and subsequent repression of c-fos transcription following serum stimulation. Genes and Development 1990; 4:255-268.

20. Greenberg ME, Shyu A-B, Belasco JG. Deadenylylation: a mechanism controlling c-fos mRNA decay. Enzyme 1990; 44:181-192.

21. Sheng M, McFadden G, Greenberg ME. Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 1990; 4:571-582.

1991

22. Shyu A-B, Belasco JG, Greenberg ME. Two distinct destabilizing elements in the c-fos message trigger deadenylylation as a first step in rapid mRNA decay. Genes and Development 1991; 5:221-231.

23. Hazel TG, Misra R, Davis IJ, Greenberg ME, Lau LF. Nur77 is differentially modified in PC12 cells upon membrane depolarization and growth factor treatment. Mol Cell Biol 1991; 11:3239-3246.

24. Sheng M, Thompson MA, Greenberg ME. CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 1991; 252:1427-1430.

25. Bading H, Greenberg ME. Stimulation of protein tyrosine phosphorylation by NMDA receptor activation. Science 1991; 253:912-914.

26. Misra RP, Rivera VM, Wang JM, Fan P-D, Greenberg ME. The serum response factor is extensively modified by phosphorylation following its synthesis in serum stimulated fibroblasts. Mol Cell Biol 1991; 11:4545-4554.

1992

27. Guitart X, Thompson MA, Miranti CK, Greenberg ME, Nestler E. Regulation of cAMP response element-binding protein (CREB) phosphorylation by acute and chronic morphine in the rat locus coeruleus. J Neurochem 1992; 58:1168-1171.

28. Greenberg ME, Thompson MA, Sheng M. Calcium regulation of immediate early gene transcription. J Physiol Paris 1992; 86:99-108.

29. Field SJ, Johnson RS, Mortensen RM, Papaioannou VE, Spiegelman BM, Greenberg ME. Growth and differentiation of embryonic stem cells that lack an intact c-fos gene. Proc Natl Acad Sci 1992; 89:9306-9310.

1993

30. Liu F, Thompson MA, Greenberg ME, Green MR. ATF-1 can mediate Ca2+ and cAMP-inducible transcriptional activation. J Biol Chem 1993; 268:6714-6720.

31. Bading H, Ginty D, Greenberg ME. Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways. Science 1993; 260:181-186.

32. Ginty DD, Kornhauser JM, Thompson MA, Bading H, Mayo KE, Takahashi JS, Greenberg ME. Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock. Science 1993; 260:238-241.

33. Wellington CL, Greenberg ME, Belasco JG. The destabilizing elements in the coding region of c-fos mRNA are recognized as RNA. Mol Cell Biol 1993; 13:5034-5042.

34. Rivera V, Misra RP, Miranti CK, Chen R-H, Blenis J, Greenberg ME. A growth factor-induced kinase cascade leads to the phosphorylation of SRF at a site that regulates its DNA binding activity. Mol Cell Biol 1993; 13:6260-6273.

35. Sucher NJ, Brose N, Deitcher DL, Awobuluyi M, Gasic GP, Bading H, Cepko CL, Greenberg ME, Jahn R, Heinemann SF, Lipton SA. Expression of Endogenous NMDA Transcripts without Receptor Protein Suggests Post-transcriptional Control in PC12 Cells. J Biol Chem 1993; 268:22299-23304.

36. Bonni A, Frank DA, Schindler C, Greenberg ME. Characterization of a Pathway for Ciliary Neurotrophic Factor Signaling to the Nucleus. Science 1993; 262:1575-1579.

1994

37. Schiavi SC, Wellington CL, Shyu A-B, Chen C-YA, Greenberg ME, Belasco JG. Multiple Elements in the c-fos Protein-coding Region Facilitate mRNA Deadenylation and Decay by a Mechanism Coupled to Translation. J Biol Chem 1994; 269:3441-3448.

38. Ghosh A, Ginty D, Bading H, Greenberg M. Calcium Regulation of Gene Expression in Neuronal Cells. J Neurobiology 1994; 25:294-303.

39. Ghosh A, Carnahan J, Greenberg ME. Requirement for BDNF in activity dependent survival of cortical neurons. Science 1994; 263:1618-1623.

40. Ginty DA, Bonni A, Greenberg ME. Nerve growth factor activates a novel Ras dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell 1994; 77:713-725.

41. Rosen LB, Ginty DD, Weber MJ, Greenberg ME. Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron 1994; 12:1207-1221.

42. Misra RP, Bonni A, Miranti CK, Rivera VM, Sheng M, Greenberg ME. L-type voltage-sensitive calcium channel activation stimulates gene expression by a serum response factor-dependent pathway. J Biol Chem 1994; 269(41):25483-25493.

1995

43. Thompson MA, Ginty DD, Bonni A, Greenberg ME. L-type voltage-sensitive Ca2+ channel activation regulates c-fos transcription at multiple levels. J Biol Chem 1995; 270(9):4224-4235.

44. Bading H, Segal MM, Sucher NJ, Dudek H, Lipton SA, Greenberg ME. NMDA receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons. Neuroscience 1995; 64(3):653-664.

45. Zubiaga AM, Belasco JG, Greenberg ME. The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation. Mol Cell Biol 1995; 15(4): 2219-2230.

46. Bonni A, Ginty DD, Dudek H, Greenberg ME. Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals. Mol Cell Neurosci 1995; 6(2):168-183.

47. Frank DA, Robertson MJ, Bonni A, Ritz J, Greenberg ME. Interleukin 2 signaling involves the phosphorylation of Stat proteins. Proc Natl Acad Sci USA 1995; 92(17):7779-7783.

48. Ghosh A, Greenberg ME. Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis. Neuron 1995; 15(1):89-103.

49. Miranti CK, Ginty DD, Huang G, Chatila T, Greenberg ME. Calcium activates serum response factor-dependent transcription by a Ras- and Elk-1-independent mechanism that involves a Ca2+/calmodulin-dependent kinase. Mol Cell Biol 1995; 15(7):3672-3684.

50. Farnsworth C, Freshney NW, Rosen LB, Ghosh A, Greenberg ME, Feig LA. Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF. Nature 1995; 376(6540):524-527.

51. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270(5240):1326-1331

52. Hirata Y, Whalin M, Ginty DD, Xing J, Greenberg ME, Milbrandt J, Guroff G. Induction of a nerve growth factor-sensitive kinase that phosphorylates the DNA-binding domain of the orphan nuclear receptor NGFI-B. J Neurochem 1995; 65(4):1780-1788.

1996

53. Rosen LB, Greenberg ME. Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels. Proc Natl Acad Sci USA 1996; 93(3):1113-1118.

54. Field SJ, Tsai FY, Kuo F, Zubiaga AM, Kaelin WG Jr, Livingston DM, Orkin SH, Greenberg ME. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 1996; 85(4):549-561.

55. Brown JR, Ye H, Bronson RT, Dikkes P, Greenberg ME. A defect in nurturing in mice lacking the immediate early gene fosB. Cell 1996; 86(2):297-309.

56. Xing J, Ginty DD, Greenberg ME. Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science 1996; 273(5277):959-963.

57. Xia Z, Dudek H, Miranti CK, Greenberg ME. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J Neurosci 1996; 16(17):5425-5436

1997

58. Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR, Greenberg ME. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 1997; 275(5300):661-665.

59. Dickens M, Rogers JS, Cavanagh J, Raitano A, Xia Z, Halpern JR, Greenberg ME, Sawyers CL, Davis RJ. A cytoplasmic inhibitor of the JNK signal transduction pathway. Science 1997; 277(5326):693-696.

60. Hiroi N, Brown JR, Haile CN, Ye H, Greenberg ME, Nestler EJ. FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects. Proc Natl Acad Sci USA 1997; 94(19):10397-10402.

61. Bonni A, Sun Y, Nadal-Vicens M, Bhatt A, Frank DA, Rozovsky I, Stahl N, Yancopoulos GD, Greenberg ME. Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway. Science 1997; 278(5337):477-483.

62. Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997; 91(2):231-241.

63. Finkbeiner S, Tavazoie SF, Maloratsky A, Jacobs KM, Harris KM, Greenberg ME. CREB: a major mediator of neuronal neurotrophin responses. Neuron 1997; 19(5):1031-1047.

1998

64. Xing J, Kornhauser JM, Xia Z, Thiele EA, Greenberg ME. Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation. Mol Cell Biol 1998; 18(4):1946-1955.

65. Tao X, Finkbeiner S, Arnold DB, Shaywitz AJ, Greenberg ME. Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron 1998; 20(4):709-726.

66. Brown JR, Nigh E, Lee RJ, Ye H, Thompson MA, Saudou F, Pestell RG, Greenberg ME. Fos family members induce cell cycle entry by activating cyclin D1. Mol Cell Biol 1998; 18(9):5609-5619.

67. Hiroi N, Marek GJ, Brown JR, Ye H, Saudou F, Vaidya VA, Duman RS, Greenberg ME, Nestler EJ. Essential role of the fosB gene in molecular, cellular, and behavioral actions of chronic electroconvulsive seizures. J Neurosci 1998; 18(17):6952-6962.

68. Saudou F, Finkbeiner S, Devys D, Greenberg ME. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell 1998; 95(1):55-66.

69. Gao Y, Sun Y, Frank KM, Dikkes P, Fujiwara Y, Seidl KJ, Sekiguchi JM, Rathbun GA, Swat W, Wang J, Bronson RT, Malynn BA, Bryans M, Zhu C, Chaudhuri J, Davidson L, Ferrini R, Stamato T, Orkin SH, Greenberg ME, Alt FW. A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell 1998; 95(7):891-902.

1999

70. Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999; 96(6):857-868.

71. Mao Z, Bonni A, Xia F, Nadal-Vicens M, Greenberg ME. Neuronal activity-dependent cell survival mediated by transcription factor MEF2. Science 1999; 286(5440):785-790.

72. Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 1999; 286(5443):1358-1362.

 

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