Mike Greenberg's Publications

Search Medline (Entrez subset) for Greenberg, ME

Original Reports:

    1979

  1. Maness PF, Engeser H, Greenberg ME, O'Farrell M, Gall WE, Edelman GM. Characterization of the protein kinase activity of avian sarcoma virus src gene product. Proc Natl Acad Sci USA 1979; 76:5028-5032.

    1983

  2. Greenberg ME, Edelman GM. Comparison of the 34,000-Da pp60src substrate and a 38,000-Da phosphoprotein identified by monoclonal antibodies. J Biol Chem 1983; 258: 8497-8502.

  3. Greenberg ME, Edelman GM. The 34 Kd pp60src substrate is located at the inner face of the plasma membrane. Cell 1983; 33:767-779.

    1984

  4. Greenberg ME, Brackenbury R, Edelman GM. Changes in the distribution of the 34-K dalton tyrosine kinase substrate during differentiation and maturation of chicken tissues. J Cell Biol 1984; 98:473-486.

  5. Greenberg ME, Brackenbury R, Edelman GM. Alteration of neural cell adhesion molecular (N-CAM) expression after neuronal cell transformation by Rous sarcoma virus. Proc Natl Acad Sci USA 1984; 81:969-973.

  6. Greenberg ME, Ziff EB. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature 1984; 311:433-438.

    1985

  7. Brackenbury R, Greenberg ME, Edelman GM. Phenotypic changes and loss of N CAM mediated adhesion in transformed embryonic chicken retinal cells. J Cell Biol 1985; 99: 1944-1954.

  8. Antler AM, Greenberg ME, Edelman GM, Hanafusa H. Increased phosphorylation of tyrosine in vinculin does not occur upon transformation by some avian sarcoma viruses. Mol Cell Biol 1985; 5:263-267.

  9. Greenberg ME, Greene LA, Ziff EB. NGF and EGF induced rapid transient changes in proto-oncogene transcription in PC12 cells. J Biol Chem 1985; 260:14101-14110.

    1986

  10. Greenberg ME, Hermanowski AL, Ziff EB. Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc and actin gene transcription. Mol Cell Biol 1986; 6:1050-1057.

  11. Greenberg ME, Ziff EB, Greene LA. Stimulation of neuronal acetylcholine receptors induces rapid gene transcription. Science 1986; 234:80-83.

    1987

  12. Greenberg ME, Siegfried Z, Ziff EB. Mutation of c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and nuclear regulatory factor binding in vitro. Mol Cell Biol 1987; 7:1217-1225.

  13. Nepveu A, Levine RA, Campisi J, Greenberg ME, Ziff EB, Marcu KB. Alternative modes of c-myc regulation in growth factor-stimulated and differentiating cells. Oncogene 1987; 1:243-250.

    1988

  1. Sheng M, Dougan ST, McFadden G, Greenberg ME. Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences. Mol Cell Biol 1988; 8:2787-2796.

  2. Halazonetis TD, Georgopoulos K, Greenberg ME, Leder P. C-jun dimerizes with itself and with c-fos forming complexes of different DNA binding affinities. Cell 1988; 55: 917-924.

    1989

  3. Shyu A-B, Greenberg ME, Belasco JG. The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways. Genes and Development 1989; 3:60-72.

  4. Bartel DP, Sheng M, Lau LF, Greenberg ME. Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction. Genes and Development 1989; 3:304-313.

  5. Johnson RS, Sheng M, Greenberg ME, Kolodner RD, Papaionannou VE, Spiegelman BM. Targeting of non-expressed genes in embryonic stem cells via homologous recombination. Science 1989; 245:1234-1236.

    1990

  6. Rivera VM, Sheng M, Greenberg ME. The inner core of the serum response element mediates both the rapid induction and subsequent repression of c-fos transcription following serum stimulation. Genes and Development 1990; 4:255-268.

  7. Greenberg ME, Shyu A-B, Belasco JG. Deadenylylation: a mechanism controlling c-fos mRNA decay. Enzyme 1990; 44:181-192.

  8. Sheng M, McFadden G, Greenberg ME. Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 1990; 4:571-582.

    1991

  9. Shyu A-B, Belasco JG, Greenberg ME. Two distinct destabilizing elements in the c-fos message trigger deadenylylation as a first step in rapid mRNA decay. Genes and Development 1991; 5:221-231.

  10. Hazel TG, Misra R, Davis IJ, Greenberg ME, Lau LF. Nur77 is differentially modified in PC12 cells upon membrane depolarization and growth factor treatment. Mol Cell Biol 1991; 11:3239-3246.

  11. Sheng M, Thompson MA, Greenberg ME. CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 1991; 252:1427-1430.

  12. Bading H, Greenberg ME. Stimulation of protein tyrosine phosphorylation by NMDA receptor activation. Science 1991; 253:912-914.

  13. Misra RP, Rivera VM, Wang JM, Fan P-D, Greenberg ME. The serum response factor is extensively modified by phosphorylation following its synthesis in serum stimulated fibroblasts. Mol Cell Biol 1991; 11:4545-4554.

    1992

  14. Guitart X, Thompson MA, Miranti CK, Greenberg ME, Nestler E. Regulation of cAMP response element-binding protein (CREB) phosphorylation by acute and chronic morphine in the rat locus coeruleus. J Neurochem 1992; 58:1168-1171.

  15. Greenberg ME, Thompson MA, Sheng M. Calcium regulation of immediate early gene transcription. J Physiol Paris 1992; 86:99-108.

  16. Field SJ, Johnson RS, Mortensen RM, Papaioannou VE, Spiegelman BM, Greenberg ME. Growth and differentiation of embryonic stem cells that lack an intact c-fos gene. Proc Natl Acad Sci 1992; 89:9306-9310.

    1993

  17. Liu F, Thompson MA, Greenberg ME, Green MR. ATF-1 can mediate Ca2+ and cAMP-inducible transcriptional activation. J Biol Chem 1993; 268:6714-6720.

  18. Bading H, Ginty D, Greenberg ME. Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways. Science 1993; 260:181-186.

  19. Ginty DD, Kornhauser JM, Thompson MA, Bading H, Mayo KE, Takahashi JS, Greenberg ME. Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock. Science 1993; 260:238-241.

  20. Wellington CL, Greenberg ME, Belasco JG. The destabilizing elements in the coding region of c-fos mRNA are recognized as RNA. Mol Cell Biol 1993; 13:5034-5042.

  21. Rivera V, Misra RP, Miranti CK, Chen R-H, Blenis J, Greenberg ME. A growth factor-induced kinase cascade leads to the phosphorylation of SRF at a site that regulates its DNA binding activity. Mol Cell Biol 1993; 13:6260-6273.

  22. Sucher NJ, Brose N, Deitcher DL, Awobuluyi M, Gasic GP, Bading H, Cepko CL, Greenberg ME, Jahn R, Heinemann SF, Lipton SA. Expression of Endogenous NMDA Transcripts without Receptor Protein Suggests Post-transcriptional Control in PC12 Cells. J Biol Chem 1993; 268:22299-23304.

  23. Bonni A, Frank DA, Schindler C, Greenberg ME. Characterization of a Pathway for Ciliary Neurotrophic Factor Signaling to the Nucleus. Science 1993; 262:1575-1579.

    1994

  24. Schiavi SC, Wellington CL, Shyu A-B, Chen C-YA, Greenberg ME, Belasco JG. Multiple Elements in the c-fos Protein-coding Region Facilitate mRNA Deadenylation and Decay by a Mechanism Coupled to Translation. J Biol Chem 1994; 269:3441-3448.

  25. Ghosh A, Ginty D, Bading H, Greenberg M. Calcium Regulation of Gene Expression in Neuronal Cells. J Neurobiology 1994; 25:294-303.

  26. Ghosh A, Carnahan J, Greenberg ME. Requirement for BDNF in activity dependent survival of cortical neurons. Science 1994; 263:1618-1623.

  27. Ginty DA, Bonni A, Greenberg ME. Nerve growth factor activates a novel Ras dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell 1994; 77:713-725.

  28. Rosen LB, Ginty DD, Weber MJ, Greenberg ME. Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron 1994; 12:1207-1221.

  29. Misra RP, Bonni A, Miranti CK, Rivera VM, Sheng M, Greenberg ME. L-type voltage-sensitive calcium channel activation stimulates gene expression by a serum response factor-dependent pathway. J Biol Chem 1994; 269(41):25483-25493.

    1995

  30. Thompson MA, Ginty DD, Bonni A, Greenberg ME. L-type voltage-sensitive Ca2+ channel activation regulates c-fos transcription at multiple levels. J Biol Chem 1995; 270(9):4224-4235.

  31. Bading H, Segal MM, Sucher NJ, Dudek H, Lipton SA, Greenberg ME. NMDA receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons. Neuroscience 1995; 64(3):653-664.

  32. Zubiaga AM, Belasco JG, Greenberg ME. The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation. Mol Cell Biol 1995; 15(4): 2219-2230.

  33. Bonni A, Ginty DD, Dudek H, Greenberg ME. Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals. Mol Cell Neurosci 1995; 6(2):168-183.

  34. Frank DA, Robertson MJ, Bonni A, Ritz J, Greenberg ME. Interleukin 2 signaling involves the phosphorylation of Stat proteins. Proc Natl Acad Sci USA 1995; 92(17):7779-7783.

  35. Ghosh A, Greenberg ME. Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis. Neuron 1995; 15(1):89-103.

  36. Miranti CK, Ginty DD, Huang G, Chatila T, Greenberg ME. Calcium activates serum response factor-dependent transcription by a Ras- and Elk-1-independent mechanism that involves a Ca2+/calmodulin-dependent kinase. Mol Cell Biol 1995; 15(7):3672-3684.

  37. Farnsworth C, Freshney NW, Rosen LB, Ghosh A, Greenberg ME, Feig LA. Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF. Nature 1995; 376(6540):524-527.

  38. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270(5240):1326-1331

  39. Hirata Y, Whalin M, Ginty DD, Xing J, Greenberg ME, Milbrandt J, Guroff G. Induction of a nerve growth factor-sensitive kinase that phosphorylates the DNA-binding domain of the orphan nuclear receptor NGFI-B. J Neurochem 1995; 65(4):1780-1788.

    1996

  40. Rosen LB, Greenberg ME. Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels. Proc Natl Acad Sci USA 1996; 93(3):1113-1118.

  41. Field SJ, Tsai FY, Kuo F, Zubiaga AM, Kaelin WG Jr, Livingston DM, Orkin SH, Greenberg ME. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell 1996; 85(4):549-561.

  42. Brown JR, Ye H, Bronson RT, Dikkes P, Greenberg ME. A defect in nurturing in mice lacking the immediate early gene fosB. Cell 1996; 86(2):297-309.

  43. Xing J, Ginty DD, Greenberg ME. Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science 1996; 273(5277):959-963.

  44. Xia Z, Dudek H, Miranti CK, Greenberg ME. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J Neurosci 1996; 16(17):5425-5436

    1997

  45. Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR, Greenberg ME. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 1997; 275(5300):661-665.

  46. Dickens M, Rogers JS, Cavanagh J, Raitano A, Xia Z, Halpern JR, Greenberg ME, Sawyers CL, Davis RJ. A cytoplasmic inhibitor of the JNK signal transduction pathway. Science 1997; 277(5326):693-696.

  47. Hiroi N, Brown JR, Haile CN, Ye H, Greenberg ME, Nestler EJ. FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects. Proc Natl Acad Sci USA 1997; 94(19):10397-10402.

  48. Bonni A, Sun Y, Nadal-Vicens M, Bhatt A, Frank DA, Rozovsky I, Stahl N, Yancopoulos GD, Greenberg ME. Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway. Science 1997; 278(5337):477-483.

  49. Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997; 91(2):231-241.

  50. Finkbeiner S, Tavazoie SF, Maloratsky A, Jacobs KM, Harris KM, Greenberg ME. CREB: a major mediator of neuronal neurotrophin responses. Neuron 1997; 19(5):1031-1047.

    1998

  51. Xing J, Kornhauser JM, Xia Z, Thiele EA, Greenberg ME. Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation. Mol Cell Biol 1998; 18(4):1946-1955.

  52. Tao X, Finkbeiner S, Arnold DB, Shaywitz AJ, Greenberg ME. Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron 1998; 20(4):709-726.

  53. Brown JR, Nigh E, Lee RJ, Ye H, Thompson MA, Saudou F, Pestell RG, Greenberg ME. Fos family members induce cell cycle entry by activating cyclin D1. Mol Cell Biol 1998; 18(9):5609-5619.

  54. Hiroi N, Marek GJ, Brown JR, Ye H, Saudou F, Vaidya VA, Duman RS, Greenberg ME, Nestler EJ. Essential role of the fosB gene in molecular, cellular, and behavioral actions of chronic electroconvulsive seizures. J Neurosci 1998; 18(17):6952-6962.

  55. Saudou F, Finkbeiner S, Devys D, Greenberg ME. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell 1998; 95(1):55-66.

  56. Gao Y, Sun Y, Frank KM, Dikkes P, Fujiwara Y, Seidl KJ, Sekiguchi JM, Rathbun GA, Swat W, Wang J, Bronson RT, Malynn BA, Bryans M, Zhu C, Chaudhuri J, Davidson L, Ferrini R, Stamato T, Orkin SH, Greenberg ME, Alt FW. A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell 1998; 95(7):891-902.

    1999

  57. Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999; 96(6):857-868.

  58. Mao Z, Bonni A, Xia F, Nadal-Vicens M, Greenberg ME. Neuronal activity-dependent cell survival mediated by transcription factor MEF2. Science 1999; 286(5440):785-790.

  59. Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 1999; 286(5443):1358-1362.

Reviews:

  1. Sheng M, Greenberg ME. The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron 1990; 4:477-485.

  2. Rivera VM, Greenberg ME. Growth factor-induced gene expression: the ups and downs of c-fos regulation. New Biol 1990; 2(9):751-758.

  3. Ginty DD, Bading H, Greenberg ME. Trans-synaptic control of gene expression. Curr Opin Neurobiol 1992; 2:312-316.

  4. Schiavi SC, Belasco JG, Greenberg ME. Regulation of proto-oncogene mRNA stability. Biochim Biophys Acta 1992; 1114:95-106.

  5. Frank DA, Greenberg ME. CREB: A mediator of long-term memory from mollusks to mammals. Cell 1994; 79:5-8.

  6. Rosen LB, Ginty DD, Greenberg ME. Calcium regulation of gene expression. Adv Second Messenger Phosphoprotein Res 1995; 30:225-253.

  7. Gallin WJ, Greenberg ME. Calcium regulation of gene expression in neurons: the mode of entry matters. Curr Opin Neurobiol 1995; 5(3):367-374.

  8. Ghosh A, Greenberg ME. Calcium signaling in neurons: molecular mechanisms and cellular consequences. Science 1995; 268(5208):239-247.

  9. Segal RA, Greenberg ME. Intracellular signaling pathways activated by neurotrophic factors. Annu Rev Neurosci 1996; 19:463-489.

  10. Finkbeiner S, Greenberg ME. Ca(2+)-dependent routes to Ras: mechanisms for neuronal survival, differentiation, and plasticity? (Minireview). Neuron 1996; 16(2):233-236.

  11. Kornhauser JM, Ginty DD, Greenberg ME, Mayo KE, Takahashi JS. Light entrainment and activation of signal transduction pathways in the SCN. Prog Brain Res 1996; 111:133-146.

  12. Kornhauser JM, Greenberg ME. A kinase to remember: Dual roles for MAP kinase in long-term memory. (Minireview). Neuron 1997; 18(6):839-842.

  13. Finkbeiner S, Greenberg ME. Spatial features of calcium-regulated gene expression. Bioessays 1997; 19(8):657-660.

  14. Bonni A, Greenberg ME. Neurotrophin regulation of gene expression. Can J Neurol Sci 1997; 24(4):272-283.

  15. Finkbeiner S, Greenberg ME. Ca2+ channel-regulated neuronal gene expression. J Neurobiol 1998; 37(1):171-89.

  16. Shaywitz AJ, Greenberg ME. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 1999; 68:821-861.

  17. Datta SR, Brunet A, Greenberg ME. Cellular survival: a play in three Akts. Genes Dev 1999; 13(22):2905-2927.

  18. Lin MZ, Greenberg ME. Orchestral maneuvers in the axon: trio and the control of axon guidance. Cell 2000; 101(3):239-242.

Books and Monographs:

  1. Maness PF, Engeser H, Greenberg ME, O'Farrell M, Gall WE, Edelman GM. Activities of the src-gene product of avian sarcoma virus. In: Cold Spring Harbor Symposia on Quantitative Biology, Volume XLIV. Cold Spring Harbor Laboratory. 1979; 949-958.

  2. Edelman GM, Hoffman S, Chuong C-M, Thiery J-P, Brackenbury R, Gallin WJ, Grumet M, Greenberg ME, Hemperly JJ, Cohen C, Cunningham BA. Structure and modulation of neural cell adhesion molecules in early and late embryogenesis. In: Cold Spring Harbor Symposia on Quantitative Biology, Volume XLVIII. Cold Spring Harbor Laboratory, 1983; 515-526.

  3. Greenberg ME, Brackenbury R, Edelman GM. Subcellular localization and tissue distribution of the 34,000-dalton tyrosine kinase substrate. In: Vande Woude GB, Levine AJ, Topp WC, Watson JP, eds. Cancer Cells, Volume 2. Cold Spring Harbor Laboratory, 1984; 99-108.

  4. Greenberg ME, Ziff EB. c-fos transcription is activated as an early response to 3T3 cell stimulation. In: Feramisco J, Ozanne B, Stiles C, eds. Cancer Cells, Volume 3. Cold Spring Harbor Laboratory, 1985; 307-314.

  5. Greene LA, Aletta JM, Burstein DE, Drexler SA, Greenberg ME, Leonard D, Ziff EB. Gene regulation by nerve growth factor. Mosback Colloquium, 1985.

  6. Greenberg ME. Identification of newly transcribed RNAs by nuclear run-off transcription. In: Ausubel, F., Brent, R., Kingston, B., Moore, D., Seidman, J., Smith, J. and Struhl, K., eds. Current Protocols in Molecular Biology, Greene Publishing.

  7. Greene LA, Greenberg ME. Proto-oncogenes in the nervous system. In: Adelman G, ed. Neuroscience Year 1988, Brikhauser Boston, Inc.

  8. Metz R, Gorham J, Siegfried Z, Leonard D, Gizang-Ginsberg E, Thompson M, Lawe D, Kouzarides T, Vosatka R, MacGregor D, Jamal S, Greenberg ME, Ziff EB. Gene regulation by growth factors. In: Cold Spring Harbor Symposia on Quantitative Biology, Volume LIII. Cold Spring Harbor Laboratory, 1989.

  9. Belasco JG, Shyu A-B, Greenberg ME. Rapid degradation of the c-fos proto oncogene transcript. In: Post-transcriptional Control of Gene Expression. JEG McCarthy and MF Tuite (eds.). Springer-Verlag, 1990.

  10. Thompson MA, Sheng M, Greenberg ME. Membrane depolarization regulation of c-fos proto-oncogene transcription. In: Costa, E. and John, TH, eds. Neurotransmitter Regulation of Gene Transcription. FIDIA Research Foundation Symposium Series, Vol. 7, 1991.

  11. Greenberg ME, Belasco JG. Control of the decay of labile protooncogene and cytokine mRNAs. In: Brawerman G and Belasco J, eds. Control of Messenger RNA Stability. San Diego: Academic Press, 1993.

  12. Misra RP, Greenberg ME, Bading H. Mechanisms of c-fos transcriptional regulation by growth factors and membrane depolarization. In: Proceedings of the Ninth International Congress on Endocrinology, Nice, France.

  13. Rosen LB, Greenberg ME. Regulation of c-fos and other immediate early genes in PC12 cells as a model for studying specificity in neuronal signaling. In: Proceedings of the Second NIMH Conference on Molecular Neurobiology.

  14. Rosen LB, Ginty DD, Greenberg ME. Calcium regulation of gene expression. In: Advances in Second Messenger and Phosphoprotein Research, Vol. 30, edited by Anthony R. Means. New York: Raven Press, Ltd., 1995.

  15. Frank DA, Greenberg ME. Signal transduction pathways activated by ciliary neurotrophic factor and related cytokines. Perspect Dev Neurobiol 1996; 4(1):3-18.

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