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 Clinical Research
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Flower General Clinical Research Center (GCRC)
The General Clinical Research Center, continuously funded by the National Institutes of Health since 1964, serves as the central focus of clinical research at Children's Hospital Boston. Its mission is to provide an optimal setting for multidisciplinary clinical research, therefore ensuring the timely translation of scientific knowledge into effective patient care.

Centrally located on the CHB campus in the Main Building (6 East), the GCRC is an eight-bed unit organized to support the care of children involved in clinical research. All patient rooms have accommodations for one parent to stay overnight with their child. The unit has a well-equipped treatment room, medication room, play-activity area, dining room and nourishment center. A metabolic kitchen that supports our protocol needs is also located on 6 East. Ambulatory GCRC for outpatient research visits is located adjacent to the inpatient unit on Pavilion 6. Support provided by the GCRC includes a Core Laboratory, and Informatics, Biostatistics, Nutrition, and Phenotype/Genotype Core Programs.

Currently, the GCRC supports 140 active protocols involving 75 different investigators representing 21 of the Hospital's departments and divisions. There is a major effort to train and mentor young clinical investigators.

GCRC Program Direction
Richard J. Grand, MD
Program Director
617-355-2962

David S. Ludwig, MD, PhD
Associate Program Director/Medical Director
617-355-4878

Robert Fuhlbrigge, MD, PhD
Associate Program Director/Protocol Development
617-355-5727

Stavroula Osganian, MD, ScD, MPH
Associate Program Director/Training & Informatics
617-355-2463

Nursing
Margaret McCabe, RN, PNP, DNSc
Director of Nursing and Patient Services
617-355-7545
Nutrition
Nicolle Quinn, MS, RD, LDN
Research Dietitian
617-355-6423
Administration
Kristine Jordan
Administrative Manager
617-355-7541
Biostatistics
Leslie Kalish, ScD
Director, Biostatistics
617-355-2461
Informatics
Joseph Rezuke, BS
Director, Informatics
617-355-9157
Research Subject Advocate
Maya Greer, APRN
617-355-5076

Stephen Brown, MD
RSA for Education
617-355-8259
Core Laboratory
Francisco Bonilla, MD, PhD
Core Laboratory Director
617-355-8594
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