Research

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Pilot Awardees


2008 - Pilot

Principal Investigator

Affiliation

Grant Title

Scott Armstrong

Hematology/Oncology

Reversal of Glucocorticoid Resistance in Acute Lymphoblastic Leukemia

Joyce Bischoff

Vascular Biology

A stem/progenitor cell that recapitulates infantile hemangoma

Gabriel Corfas

Neurology

GDNF receptor agonists to treat peripheral neuropathies

Robert Husson

Infectious Diseases

Proteome-wide screen for M. tuberculosis antigens

Richard Malley

Infectious Diseases

A transcutaneous vaccine to prevent pneumococcal colonization and disease

Benjamin Matthews

Critical Care

Microparticles with TRPV4 inhibitor for lung protection

Umut Ozcan

Endocrinology

Role of ER Stress in Development of Leptin Resistance

Mark Puder

Surgery

The essentiality of archidonic acid (AA), docosahexaaenoic acid (DHA)

Leslie Silberstein

Blood Bank/Transfusion Medicine

Novel Approaches in Targeting Pediatric B-ALL

2009 - Pilot

Principal Investigator

Affiliation

Grant Title

Joyce Bischoff

Vascular Biology

A stem/progenitor cell that recapitulates infantile hemangoma

Wayne Lencer

Gastroenterology

Novel platform for mucosal protein drug/vaccine delivery and increased half-life

Luigi Notarangelo

Immunology

Use of engineered meganucleases to correct RAG1 deficiency in humans

Alexander Rotenberg

Neurology

Treatment of Status Epilepticus by Transcranial Direct Current Stimulation

Janet Soul

Neurology

Pilot Trial of Bumetanide to Treat Neonatal Seizures

Hanno Steen

Pathology

Urine proteomics of Kawasaki disease and pediatric vasculitis

Dale Umetsu

Immunology

A Novel Therapy for Severe Food Allergy by Rapid and Safe Induction of Oral Tolerance

2010 - Pilot

Principal Investigator

Affiliation

Grant Title

Xi He

Neurology

Chemical inhibition of a novel Wnt modulator for osteoporosis therapeutics

Jordan Kreidberg

Nephrology

c-Met inhibitor treatment of Polycystic Kidney Disease

David Ludwig

Endocrinology

Effects of a food preservative on glucose Homeostasis

Alexander Rotenberg

Neurology

Closed-loop adjustment of transcranial direct current stimulation (tDCS) in of status epilepticus

Dale Umetsu

Immunology

Renewal: A novel therapy for severe food allergy by rapid and safe induction of oral tolerance

Dennis Wall

Medicine/Informatics

Deciphering autism through cross-disease system biology

Gerhard Wolf

Anesthesia

Reducing ventilator-associated lung injury through non-invasive bedside imaging

2011 - Pilot

Principal Investigator

Affiliation

Grant Title

Paolo Fiorina

Medicine

Role of B7.1 in Diabetic Nephropathy

Rani George

Oncology

Validation of a Genetically Engineered Mouse Model of Neuroblastoma Drive by Mutated AIK and MYCN

Takao Hensch 

Neurology

Recovery from Amblyopia with Cholinesterase Inhibitors

Joel Hirschhorn 

Endocrinology

New Genetic Classes of Idiopathic Short Stature Defined by Sequence and Copy Number Variants

Robert Husson

Infectious Disease

Stress-Potential Screens to Identify Novel Inhibitors of M. Tuberculosis

Omar Khwaja

Neurology

Pilot Trial of Mecasermin (rDNA) Injection to Treat Rett Syndrome

Hannah Kinney 

Pathology

Potential Clinical Biomarkers of SIDS

Brian Snyder 

Orthopaedics

Development of Contrast Enhanced Quantitative CT as Clinical Tool for Arthritis

2012 - Pilot

Principal Investigator

Affiliation

Grant Title

William Bosl

Endocrinology

Biomarkers for Early Identification of Children with Epileptic Encephalopathies

Larry Benowitz

Neurosurgery

The Effects of Inosine in Promoting Recovery after Spinal Cord Injury

Pedro del Nido

Cardiovascular Surgery

A Novel Light-Activated Adhesive for Pediatric Cardiovascular Applications

Paolo Fiorina

Nephrology

Role of B7.1 in Diabetic Nephropathy: Establishing the CTLA4-lg Clinical Trial

Xi He

Neurology

A Novel Strategy for Turning off β-catenin Oncogenic Signaling in Cancer

Matthew Heeney

Hematology/Oncology

Pilot Trial of Glycine Supplementation in Autosomal Recessive Congenital Sideroblastic Anemia Due to Mutations in SLC25A38

Richard Lee

Urology

Early Validation of Urinary Biomarkers of Renal Obstruction

Richard Malley

Infectious Disease

Development of a Multiple Antigen Presentation System (MAPS) Pneumococcal Vaccine

Martha Murray

Orthopaedics

Regeneration of the Anterior Cruciate Ligament after Rupture

Hans Oettgen

Immunology

Safe Food Allergy Desensitization using IgE Receptor Signaling Inhibitors

Simon Warfield

Radiology

Diffusion-Weighted MRI for the Assessment of Disease Activity and Progression in Pediatric Chron’s Disease

2013 - Pilot

Principal Investigator

 Affiliation

 Grant Title

Joyce Bischoff

Vascular Biology Program

Cellular and Molecular Basis of Lymphatic Malformations

Talal Chatila

 Immunology

Regulatory T Cell Bio-Markers of Food Allergy Outcomes

Roberto Chiarle

 Pathology

ALK Tumor Vaccine in Neuroblastoma

Steven Colan

 Cardiology

Novel Cardiac Biomarkers and Tissue Doppler Imaging for Rejection Surveillance after Pediatric Heart Transplantation

Pedro del Nido

Cardiac Surgery

Novel Strategies for Intracardiac Septal Defect Closure

Michela Fagiolini

Neurology

Pre-Clinical and Clinical Testing of NMDAr Antagonist Treatment in Rett Syndrome

Medhi Hedjazi Moghari

Cardiology

Accelerated 3D-SSFP Magnetic Resonance Imaging for Guiding Congenital Heart Disease Management 


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