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Nikolay V. Vasilyev, MD

Nikolay V. Vasilyev, MD
Department:
Cardiac Surgery Research
Hospital Title:
Staff Scientist
Academic Title:
Assistant Professor of Surgery
Research Focus Area:
Cardiac Surgery
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Research Overview

Nikolay V. Vasilyev's research interests include development of image-guided beating-heart intracardiac interventions. In particular, his research is focused on instruments and device design for valve interventions and septal defects closure, new imaging techniques, computer modeling and simulation. In addition, Dr. Vasilyev has been working on developing of novel concepts for atrio-ventricular valve annuloplasty.

About Nikolay V. Vasilyev, MD

Dr. Vasilyev graduated from Moscow Medical Academy. He completed residency in cardiovascular surgery and fellowship in pediatric cardiovascular surgery at A.N. Bakoulev Center for Cardiovascular Surgery in Moscow. Dr. Vasilyev completed his research fellowship at the Cleveland Clinic.

Key Publications

  • Vasilyev NV, Dupont PE, Del Nido PJ. Robotics and imaging in congenital heart surgery. Future Cardiol. 2012 Mar;8(2):285-96.

  • Vasilyev NV, Kawata M, DiBiasio CM, Durand KV, Hopkins J, Traina ZJ, Slocum AH, del Nido PJ. A novel cardioport for beating-heart, image-guided intracardiac surgery. J Thorac Cardiovasc Surg. 2011 Dec;142(6):1545-51.

  • Ren H, Vasilyev NV, Dupont PE. Detection of Curved Robots using 3D Ultrasound. Rep U S. 2011 Sep 25;2011:2083-2089.

  • Perrin DP, Vasilyev NV, Novotny P, Stoll J, Howe RD, Dupont PE, Salgo IS, del Nido PJ. Image Guided Surgical Interventions. Curr Probl Surg. 2009 Sep;46(9):730-66.

  • Vasilyev NV, Novotny PM, Martinez JF, Loyola H, Salgo IS, Howe RD, del Nido PJ. Stereoscopic Vision Display Technology in Real-Time Three-Dimensional Echocardiography-Guided Intracardiac Beating-Heart Surgery. J Thorac Cardiovasc Surg. 2008 Jun;135(6):1334-41.

  • Hoch M, Vasilyev N, Soriano B, Gauvreau K, Marx GR. Variables Influencing the Accuracy of Right Ventricular Volume Assessment by Real-time 3-Dimensional Echocardiography: An In Vitro Validation Study. J Am Soc Echocardiogr. 2007 May;20(5):456-461.

  • Vasilyev NV, Martinez JF, Freudenthal FP, Suematsu Y, Marx GR, del Nido PJ. Three-Dimensional Echo and Videocardioscopy-Guided Atrial Septal Defect Closure. Ann Thorac Surg; 2006 Oct;82(4):1322-6.

All publications in PubMed

Publications

Publications powered by Harvard Catalyst Profiles
  1. Ataollahi A, Berra I, Vasilyev NV, Machaidze Z, Dupont PE. Cardioscopic Tool-delivery Instrument for Beating-heart Surgery. IEEE ASME Trans Mechatron. 2016 Feb; 21(1):584-590.
  2. Roche ET, Fabozzo A, Lee Y, Polygerinos P, Friehs I, Schuster L, Whyte W, Casar Berazaluce AM, Bueno A, Lang N, Pereira MJ, Feins E, Wasserman S, O'Cearbhaill ED, Vasilyev NV, Mooney DJ, Karp JM, Del Nido PJ, Walsh CJ. A light-reflecting balloon catheter for atraumatic tissue defect repair. Sci Transl Med. 2015 Sep 23; 7(306):306ra149.
  3. Bergeles C, Gosline AH, Vasilyev NV, Codd PJ, Del Nido PJ, Dupont PE. Concentric Tube Robot Design and Optimization Based on Task and Anatomical Constraints. IEEE Trans Robot. 2015 Feb 3; 31(1):67-84.
  4. Roche ET, Hastings CL, Lewin SA, Shvartsman DE, Brudno Y, Vasilyev NV, O'Brien FJ, Walsh CJ, Duffy GP, Mooney DJ. Comparison of biomaterial delivery vehicles for improving acute retention of stem cells in the infarcted heart. Biomaterials. 2014 Aug; 35(25):6850-8.
  5. Roche ET, Wohlfarth R, Overvelde JT, Vasilyev NV, Pigula FA, Mooney DJ, Bertoldi K, Walsh CJ. A bioinspired soft actuated material. Adv Mater. 2014 Feb 26; 26(8):1200-6.
  6. Yamauchi H, Feins EN, Vasilyev NV, Shimada S, Zurakowski D, Del Nido PJ. Creation of nonischemic functional mitral regurgitation by annular dilatation and nonplanar modification in a chronic in vivo swine model. Circulation. 2013 Sep 10; 128(11 Suppl 1):S263-70.
  7. Vasilyev NV, Gosline AH, Butler E, Lang N, Codd PJ, Yamauchi H, Feins EN, Folk CR, Cohen AL, Chen R, Zurakowski D, del Nido PJ, Dupont PE. Percutaneous steerable robotic tool delivery platform and metal microelectromechanical systems device for tissue manipulation and approximation: closure of patent foramen ovale in an animal model. Circ Cardiovasc Interv. 2013 Aug; 6(4):468-75.
  8. Gosline AH, Vasilyev NV, Butler EJ, Folk C, Cohen A, Chen R, Lang N, Del Nido PJ, Dupont PE. Percutaneous intracardiac beating-heart surgery using metal MEMS tissue approximation tools. Int J Rob Res. 2012 Aug 1; 31(9):1081-1093.
  9. Yap CH, Saikrishnan N, Tamilselvan G, Vasilyev N, Yoganathan AP. The congenital bicuspid aortic valve can experience high-frequency unsteady shear stresses on its leaflet surface. Am J Physiol Heart Circ Physiol. 2012 Sep 15; 303(6):H721-31.
  10. Saikrishnan N, Yap CH, Milligan NC, Vasilyev NV, Yoganathan AP. In vitro characterization of bicuspid aortic valve hemodynamics using particle image velocimetry. Ann Biomed Eng. 2012 Aug; 40(8):1760-75.
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  12. Gosline AH, Vasilyev NV, Veeramani A, Wu M, Schmitz G, Chen R, Arabagi V, Del Nido PJ, Dupont PE. Metal MEMS Tools for Beating-heart Tissue Removal. IEEE Int Conf Robot Autom. 2012.
  13. Tenenholtz NA, Hammer PE, Schneider RJ, Vasilyev NV, Howe RD. On the Design of an Interactive, Patient-Specific Surgical Simulator for Mitral Valve Repair. Rep U S. 2011 Dec 31; 2011:1327-1332.
  14. Butler EJ, Folk C, Cohen A, Vasilyev NV, Chen R, Del Nido PJ, Dupont PE. Metal MEMS Tools for Beating-heart Tissue Approximation. IEEE Int Conf Robot Autom. 2011 May 9; 2011:411-416.
  15. Lang N, Kozlik-Feldmann R, Meyer-Gold A, Fuchs F, Lehner A, Abicht J, Sodian R, Vasilyev N, del Nido P, Netz H, Reichart B, Schmitz C. Modification of a hybrid technique for closure of muscular ventricular septal defects in a pig model. Heart Surg Forum. 2010 Oct; 13(5):E299-304.
  16. Yuen SG, Vasilyev NV, del Nido PJ, Howe RD. Robotic tissue tracking for beating heart mitral valve surgery. Med Image Anal. 2013 Dec; 17(8):1236-42.
  17. Schneider RJ, Perrin DP, Vasilyev NV, Marx GR, del Nido PJ, Howe RD. Mitral annulus segmentation from 3D ultrasound using graph cuts. IEEE Trans Med Imaging. 2010 Sep; 29(9):1676-87.
  18. Yuen SG, Yip MC, Vasilyev NV, Perrin DP, Del Nido PJ, Howe RD. Robotic Force Stabilization for Beating Heart Intracardiac Surgery. Med Image Comput Comput Assist Interv. 2009 Oct 1; 5761(2009):26-33.
  19. Perrin DP, Vasilyev NV, Novotny P, Stoll J, Howe RD, Dupont PE, Salgo IS, del Nido PJ. Image guided surgical interventions. Curr Probl Surg. 2009 Sep; 46(9):730-66.
  20. Yuen SG, Yip MC, Vasilyev NV, Perrin DP, del Nido PJ, Howe RD. Robotic force stabilization for beating heart intracardiac surgery. Med Image Comput Comput Assist Interv. 2009; 12(Pt 1):26-33.
  21. Schneider RJ, Perrin DP, Vasilyev NV, Marx GR, Del Nido PJ, Howe RD. Mitral Annulus Segmentation from Three-Dimensional Ultrasound. Proc IEEE Int Symp Biomed Imaging. 2009; 779-782.
  22. Huang J, Triedman JK, Vasilyev NV, Suematsu Y, Cleveland RO, Dupont PE. Imaging artifacts of medical instruments in ultrasound-guided interventions. J Ultrasound Med. 2007 Oct; 26(10):1303-22.
  23. Linguraru MG, Vasilyev NV, Del Nido PJ, Howe RD. Statistical segmentation of surgical instruments in 3-D ultrasound images. Ultrasound Med Biol. 2007 Sep; 33(9):1428-37.
  24. Vasilyev NV, Martinez JF, Freudenthal FP, Suematsu Y, Marx GR, del Nido PJ. Three-dimensional echo and videocardioscopy-guided atrial septal defect closure. Ann Thorac Surg. 2006 Oct; 82(4):1322-6; discussion 1326.
  25. Novotny PM, Jacobsen SK, Vasilyev NV, Kettler DT, Salgo IS, Dupont PE, Del Nido PJ, Howe RD. 3D ultrasound in robotic surgery: performance evaluation with stereo displays. Int J Med Robot. 2006 Sep; 2(3):279-85.
  26. Friehs I, Barillas R, Vasilyev NV, Roy N, McGowan FX, del Nido PJ. Vascular endothelial growth factor prevents apoptosis and preserves contractile function in hypertrophied infant heart. Circulation. 2006 Jul 4; 114(1 Suppl):I290-5.
  27. Novotny PM, Stoll JA, Vasilyev NV, del Nido PJ, Dupont PE, Howe RD. GPU based real-time instrument tracking with three dimensional ultrasound. Med Image Comput Comput Assist Interv. 2006; 9(Pt 1):58-65.
  28. Mumtaz MA, Fraga CH, Nicholls CM, Desai S, Vasilyev N, Joshi R, Mee RB, Duncan BW. Increased expression of vascular endothelial growth factor messenger RNA in lungs of rats after cavopulmonary anastomosis. J Thorac Cardiovasc Surg. 2005 Jan; 129(1):209-10.
  29. Yamauchi H, Vasilyev NV, Marx GR, Loyola H, Padala M, Yoganathan AP, del Nido PJ. Right ventricular papillary muscle approximation as a novel technique of valve repair for functional tricuspid regurgitation in an ex vivo porcine model. J Thorac Cardiovasc Surg. 2012 Jul; 144(1):235-42.
  30. Kozlik-Feldmann R, Lang N, Aumann R, Lehner A, Rassoulian D, Sodian R, Schmitz C, Hinterseer M, Hinkel R, Thein E, Freudenthal F, Vasilyev NV, Vasylev NV, del Nido PJ, Netz H. Patch closure of muscular ventricular septal defects with a new hybrid therapy in a pig model. J Am Coll Cardiol. 2008 Apr 22; 51(16):1597-603.
  31. Vasilyev N, Williams T, Brennan ML, Unzek S, Zhou X, Heinecke JW, Spitz DR, Topol EJ, Hazen SL, Penn MS. Myeloperoxidase-generated oxidants modulate left ventricular remodeling but not infarct size after myocardial infarction. Circulation. 2005 Nov 1; 112(18):2812-20.
  32. Schneider RJ, Perrin DP, Vasilyev NV, Marx GR, del Nido PJ, Howe RD. Mitral annulus segmentation from four-dimensional ultrasound using a valve state predictor and constrained optical flow. Med Image Anal. 2012 Feb; 16(2):497-504.
  33. Vasilyev NV, Kawata M, DiBiasio CM, Durand KV, Hopkins J, Traina ZJ, Slocum AH, del Nido PJ. A novel cardioport for beating-heart, image-guided intracardiac surgery. J Thorac Cardiovasc Surg. 2011 Dec; 142(6):1545-51.
  34. Walter EM, Delmo Walter EM, Vasilyev NV, Sill B, Padala M, Jimenez J, Yoganathan AP, Hetzer R, del Nido PJ. Creation of a tricuspid valve regurgitation model from tricuspid annular dilatation using the cardioport video-assisted imaging system. J Heart Valve Dis. 2011 Mar; 20(2):184-8.
  35. Vasilyev NV, Dupont PE, del Nido PJ. Robotics and imaging in congenital heart surgery. Future Cardiol. 2012 Mar; 8(2):285-96.
  36. Schneider RJ, Perrin DP, Vasilyev NV, Marx GR, Del Nido PJ, Howe RD. Real-time image-based rigid registration of three-dimensional ultrasound. Med Image Anal. 2012 Feb; 16(2):402-14.
  37. Linguraru MG, Vasilyev NV, Marx GR, Tworetzky W, Del Nido PJ, Howe RD. Fast block flow tracking of atrial septal defects in 4D echocardiography. Med Image Anal. 2008 Aug; 12(4):397-412.
  38. Yuen SG, Kesner SB, Vasilyev NV, Del Nido PJ, Howe RD. 3D ultrasound-guided motion compensation system for beating heart mitral valve repair. Med Image Comput Comput Assist Interv. 2008; 11(Pt 1):711-9.
  39. Novotny PM, Stoll JA, Vasilyev NV, del Nido PJ, Dupont PE, Zickler TE, Howe RD. GPU based real-time instrument tracking with three-dimensional ultrasound. Med Image Anal. 2007 Oct; 11(5):458-64.
  40. Perrin DP, Vasilyev NV, Marx GR, del Nido PJ. Temporal enhancement of 3D echocardiography by frame reordering. JACC Cardiovasc Imaging. 2012 Mar; 5(3):300-4.
  41. Padala M, Vasilyev NV, Owen JW, Jimenez JH, Dasi LP, del Nido PJ, Yoganathan AP. Cleft closure and undersizing annuloplasty improve mitral repair in atrioventricular canal defects. J Thorac Cardiovasc Surg. 2008 Nov; 136(5):1243-9.
  42. Vasilyev NV, Melnychenko I, Kitahori K, Freudenthal FP, Phillips A, Kozlik-Feldmann R, Salgo IS, del Nido PJ, Bacha EA. Beating-heart patch closure of muscular ventricular septal defects under real-time three-dimensional echocardiographic guidance: a preclinical study. J Thorac Cardiovasc Surg. 2008 Mar; 135(3):603-9.
  43. Kawata M, Vasilyev NV, Perrin DP, del Nido PJ. Beating-heart mitral valve suture annuloplasty under real-time three-dimensional echocardiography guidance: an ex vivo study. Interact Cardiovasc Thorac Surg. 2010 Jul; 11(1):6-9.
  44. Hoch M, Vasilyev NV, Soriano B, Gauvreau K, Marx GR. Variables influencing the accuracy of right ventricular volume assessment by real-time 3-dimensional echocardiography: an in vitro validation study. J Am Soc Echocardiogr. 2007 May; 20(5):456-61.
  45. Linguraru MG, Vasilyev NV, del Nido PJ, Howe RD. Atrial septal defect tracking in 3D cardiac ultrasound. Med Image Comput Comput Assist Interv. 2006; 9(Pt 1):596-603.
  46. Vasilyev NV, Novotny PM, Martinez JF, Loyola H, Salgo IS, Howe RD, del Nido PJ. Stereoscopic vision display technology in real-time three-dimensional echocardiography-guided intracardiac beating-heart surgery. J Thorac Cardiovasc Surg. 2008 Jun; 135(6):1334-41.
  47. Ren H, Vasilyev NV, Dupont PE. Detection of Curved Robots using 3D Ultrasound. Rep U S. 2011 Sep 25; 2011:2083-2089.
  48. Kozlik-Feldmann R, Lang N, Lehner A, Sigler M, Schmitz C, Sodian R, Freudenthal F, Dalla-Pozza R, Vasilyev NV, del Nido PJ, Netz H. Evaluation of a new hybrid technique for closure of muscular ventricular septal defects in a long-term setting. J Thorac Cardiovasc Surg. 2009 Aug; 138(2):365-73.
  49. Feins EN, Yamauchi H, Marx GR, Freudenthal FP, Liu H, Del Nido PJ, Vasilyev NV. Repair of posterior mitral valve prolapse with a novel leaflet plication clip in an animal model. J Thorac Cardiovasc Surg. 2014 Feb; 147(2):783-90; discussion 790-1.
  50. Lang N, Pereira MJ, Lee Y, Friehs I, Vasilyev NV, Feins EN, Ablasser K, O'Cearbhaill ED, Xu C, Fabozzo A, Padera R, Wasserman S, Freudenthal F, Ferreira LS, Langer R, Karp JM, del Nido PJ. A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects. Sci Transl Med. 2014 Jan 8; 6(218):218ra6.
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