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Khashayar  Vakili, MD

Khashayar vakili
Surgery Research
Hospital Title:
Assistant in Surgery
Academic Title:
Assistant Professor of Surgery, Harvard Medical School
Research Focus Area:
Liver tumor biologyLiver regenerationLiver tissue engineering
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Research Overview

Dr. Vakili is a surgeon who specializes in transplantation of liver, kidney, and intestines. His clinical practice also encompasses surgical treatment of liver tumors as well as various vascular procedures. Dr. Vakili’s basic science research involves liver regeneration, liver tumor biology, and liver tissue engineering.

Dr. Vakili is specifically interested in developing a better understanding of pediatric hepatocellular carcinoma biology with the aim of developing new therapies as no effective chemotherapeutic agents are currently available for this type of tumor. His approach involves an in-depth study of tumors from individual patients. Currently, significant efforts are underway in identifying key genetic changes and signaling pathways in liver tumor cells using patient-derived tumor samples.

Key Publications

  • Vakili K, Pomposelli JJ, Cheah YL, Akoad M, Lewis WD, Khettry U, Gordon FD, Khwaja K, Jenkins RL, Pomfret EA. Living-donor liver transplantation for hepatocellular carcinoma: Increased recurrence but improved survival. Liver Transplantation. 2009; 15(12): 1861-6.
  • Kim HB, Vakili K, Modi BP, Ferguson M, Guillot AP, Potanos KM, Prabhu S, Fishman SJ. A Novel Treatment for Midaortic Syndrome. N Engl J Med. 2012 Dec 13; 367(24):2361-2.
  • Vakili K, Fullington NM, Cauley RP, Potanos KM, Lee SI, Turner CG, Ferguson M, Lock, JE, Kim HB. Aortomesenteric and Renal Allograft Transplant: A Novel Treatment for Midaortic Syndrome. American Journal of Transplantation. 2013 Apr; 13(4):1088-92.
  • Cauley RP, Vakili K, Potanos K, Fullington N, Graham DA, Finkelstein JA, Kim HB. Deceased donor liver transplantation in infants and small children: are partial grafts riskier than whole organs? Liver Transpl. 2013 Jul; 19(7):721-9.
  • Porras D, Stein DR, Ferguson MA, Chaudry G, Alomari A, Vakili K, Fishman SJ, Lock JE, Kim HB. Midaortic syndrome: 30 years of experience with medical, endovascular and surgical management.Pediatr Nephrol. 2013 Jun 18.
  • Bairdain S, Modi BP, Kim HB, Mooney DP, Durkin E, Vakili K. Pediatric blunt abdominal aortic injury and the use of intra-operative aortic ultrasound for surgical decision making. J Pediatr Surg. 2013 Jul; 48(7):1584-7.
  • Cauley RP, Vakili K, Fullington N, Potanos K, Graham DA, Finkelstein JA, Kim HB. Deceased-donor split-liver transplantation in adult recipients: Is the learning curve over? J Am Coll Surg. 2013 Oct; 217(4):672-684.
  • Vakili K and Kim HB. Partial esophageal transplant is possible as part of a multivisceral graft. Am J Transplant 2014 Mar;14(3):720-3.
  • Grijalva J, Huizenga M, Mueller K, Rodriguez S, Brazzo J, Camargo F, Sadri-Vakili G, Vakili K. Dynamic alterations in Hippo signaling pathway and YAP activation during liver regeneration. American Journal of Physiology: Gastrointestinal and Liver Physiology. 2014 Jul 15; 307(2):G196-204.
  • Fullington N, Cauley R, Potanos K, O'Melia L, Kim, HB, Seefelder C, Vakili K. Immediate extubation after pediatric liver transplantation: A single center experience. Liver Transplantation. Liver Transplantation. 2015 Jan; 21(1):57-62.
  • Cauley R, Potanos K, Fullington N, Grijalva J, Graham D, Kim HB, Vakili K. The effect of graft type on mortality in liver transplantation for hepatocellular carcinoma. Annals of Transplantation. Annals of Transplantation. 2015 Apr; 20:175-185.
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