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Robert Shamberger, MD

Robert Shamberger MD
Surgery Research
Hospital Title:
Chief, Department of Surgery
Academic Title:
Robert E. Gross Professor of Surgery, Harvard Medical School
Research Focus Area:
Cancer and bowel surgery
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Research Overview

The goals of Robert Shamberger's research are to:

  • Define the optimal multimodal therapy for patients with neuroblastoma, Ewings sarcoma and Wilms tumor with particular emphasis in the surgical modality.
  • Establish the clinical outcome and quality of life of children with inflammatory bowel disease and to establishhow various forms of surgical therapy affect those outcomes.

He is currently active in the design and analysis of multi-institutional protocols of neuroblastoma, Wilms tumor and chest wall sarcomas through the Children's Oncology Group. He is also a principal investigator of an institutional prospective study of the quality of life outcomes of children and adolescents who have a total abdominal colectomy and ileoanal pullthrough for ulcerative colitis or familial adenomatous polyposis and a multi-institutional prospective study of the surgical management of pectus excavatum.

About Robert Shamberger

Robert Shamberger received his MD from Harvard Medical School. He completed an internship and residency in surgery at the Massachusetts General Hospital and a fellowship in pediatric surgery at Children's Hospital Boston and a surgical oncology fellowship at the National Cancer Institute, Bathesda, MD.

Key Publications

  • Shamberger RC, Holzman RS, Griscom NT, Tarbell NJ, Weinstein HJ, Wohl ME. Prospective evaluation by computed tomography and pulmonary function tests of children with mediastinal masses. Surgery 1995; 118: 468-471.
  • Shamberger RC, Leichtner AM, Jonas MM, LaQuaglia MP. Long-term hepatic regeneration and function in infants and children for ulcerative colitis and familial adenomatous polyposis. J Am Coll Surg 1996; 182: 515-519.
  • Shamberger RC, Masek BJ, Leichtner AM, Winter HS, Lillehei CW. Quality of life assessment following ileoanal pullthrough for ulcerative colitis and familial adenomatous polyposis. J Pediatr Surg 1999; 34: 163-166.
  • Shamberger RC, Guthrie KA, Ritchey ML, Haase GM, Takashima J, Beckwith JB, D'Angio GJ, Green DM, Breslow NE. Surgery-related factors and local recurrence of Wilms tumor in National Wilms Tumor Study-4. Ann Surg 1999; 229: 292-297.
  • Shamberger RC, LaQuaglia MP, Krailo MD, Miser JS, Pritchard DJ, Gebhardt MC, Healey JH, Tarbell NJ, Fryer CJH, Meyers PA, Grier HE. Ewing sarcoma of the rib: Results of an intergroup study with analysis of outcome by timing of resection. J Thorac Cardiovasc Surg 2000; 119: 1154-1161.
  • Shamberger RC, Ritchey ML, Haase GM, Bergemann TL, Loechelt-Yoshioka T, Breslow NE, Green DM. Intravascular extension of Wilms tumor. Ann Surg 2001; 234: 116-121.
  • Shamberger RC, LaQuaglia MP, Gebhardt MC, Neff JR, Tarbell NJ, Marcus KC, Sailer SL, Womer RB, Miser JS, Dickman PS, Perlman EJ, Devidas M, Linda SB, Krailo MP, Grier HE, Granowetter L. Ewing sarcoma/primitive neuroectodermal tumor of the chest wall: Impact of initial versus delayed resection on tumor margins, survival, and use of radiation therapy. Ann Surg 2003; 238: 563-568.
  • von Allmen D, Grupp S, Diller L, Marcus K, Ecklund K, Meyer J, Shamberger RC. Aggressive surgical therapy and radiotherapy for patients with high-risk neuroblastoma treated with rapid sequence tandem transplant. J Pediatr Surg 2005; 40: 936-941.
  • Kelly RE Jr, Shamberger RC, Mellins RB, Mithcell KK, Lawson ML, Oldham K, Azizkhan RG, Hebra AV, Nuss D, Goretsky MJ, Sharp RJ, Holcomb GW III, Shim WKT, Megison SM, Moss RL, Fecteau AH, Colombani PM, Bagley TC, Moscowitz AB. Prospective multicenter study of surgical correction of pectus excavatum: Design, perioperative complications, pain, and baseline pulmonary function facilitated by internet-based data collection. J Am Coll Surg 2007; 205: 205-216.
  • Kelly RE Jr, Cash TF, Shamberger RC, Mitchell KK, Mellins RB, Lawson ML, Oldham K, Azizkhan RG, Hebra AV, Nuss D, Goretsky MJ, Sharp RJ, Holcombe GW III, Shim WKT, Megison SM, Moss RL, Fecteau AH, Colombani PM, Bagley T, Quinn A, Moskowitz AB. Surgical repair of pectus excavatum markedly improves body image and perceived ability for physical activity: A multicenter study. Pediatrics 2008; 122: 1218-1222.
  • All of Dr. Shamberger publications on PubMed
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