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Stavroula  Osganian, MD, ScD

Stavroula Osganian
Medicine Research
General Pediatrics Research
Hospital Title:
Co-Chief, Clinical Research Center
Academic Title:
Assistant Professor of Pediatrics, Harvard Medical School
Research Focus Area:
Obesity prevention
Contact Via Email
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Research Overview

Dr. Osganian's research interests and activities have focused on studies of youth cardiovascular health promotion including obesity, smoking cessation, and nutritional supplement interventions. She has had a leadership role in one of the largest, nationally recognized NIH-funded school-based studies of cardiovascular health promotion in the United States, the Child and Adolescent Trial for Cardiovascular Health (CATCH) as well as several other epidemiological and school or community based studies.

About Stavroula Osganian, MD, ScD, MPH

Stavroula Osganian received an MD degree from UMASS Worcester Medical School, an MPH from UMASS Amherst School of Public Health, and an ScD from Harvard School of Public Health. She completed an internship in Pediatrics at New England Medical Center Floating Hospital for Children, a Preventive Medicine residency and Preventive Cardiology research fellowship at UMASS Medical Center, Worcester.

Active Projects

2014 POOL Research Registry: A Registry of Obese and Overweight Youth at Boston Children’s Hospital

The Milton Fund

This project will establish a well characterized cohort of obese and overweight patients at Boston Children’s Hospital as well as a biorepository of specimens in order to conduct research to better understand the biologic mechanisms of obesity and develop new and more effective approaches to prevention and treatment. 


Publications powered by Harvard Catalyst Profiles
  1. Pbert L, Druker S, Barton B, Schneider KL, Olendzki B, Gapinski MA, Kurtz S, Osganian S. A School-Based Program for Overweight and Obese Adolescents: A Randomized Controlled Trial. J Sch Health. 2016 Oct; 86(10):699-708.
  2. Thaker VV, Lee F, Bottino CJ, Perry CL, Holm IA, Hirschhorn JN, Osganian SK. Impact of an Electronic Template on Documentation of Obesity in a Primary Care Clinic. Clin Pediatr (Phila). 2016 Oct; 55(12):1152-9.
  3. Crouter SE, de Ferranti SD, Whiteley J, Steltz SK, Osganian SK, Feldman HA, Hayman LL. Effect on Physical Activity of a Randomized Afterschool Intervention for Inner City Children in 3rd to 5th Grade. PLoS One. 2015; 10(10):e0141584.
  4. Denhoff ER, Milliren CE, de Ferranti SD, Steltz SK, Osganian SK. Factors Associated with Clinical Research Recruitment in a Pediatric Academic Medical Center--A Web-Based Survey. PLoS One. 2015; 10(10):e0140768.
  5. de Ferranti SD, Milliren CE, Denhoff ER, Quinn N, Osganian SK, Feldman HA, Ebbeling CB, Ludwig DS. Providing food to treat adolescents at risk for cardiovascular disease. Obesity (Silver Spring). 2015 Oct; 23(10):2109-17.
  6. Peterson KE, Spadano-Gasbarro JL, Greaney ML, Austin SB, Mezgebu S, Hunt AT, Blood EA, Horan C, Feldman HA, Osganian SK, Bettencourt MF, Richmond TK. Three-Year Improvements in Weight Status and Weight-Related Behaviors in Middle School Students: The Healthy Choices Study. PLoS One. 2015; 10(8):e0134470.
  7. Maahs DM, Daniels SR, de Ferranti SD, Dichek HL, Flynn J, Goldstein BI, Kelly AS, Nadeau KJ, Martyn-Nemeth P, Osganian SK, Quinn L, Shah AS, Urbina E. Cardiovascular disease risk factors in youth with diabetes mellitus: a scientific statement from the American Heart Association. Circulation. 2014 Oct 21; 130(17):1532-58.
  8. de Ferranti SD, Milliren CE, Denhoff ER, Steltz SK, Selamet Tierney ES, Feldman HA, Osganian SK. Using high-dose omega-3 fatty acid supplements to lower triglyceride levels in 10- to 19-year-olds. Clin Pediatr (Phila). 2014 May; 53(5):428-38.
  9. Pbert L, Druker S, Gapinski MA, Gellar L, Magner R, Reed G, Schneider K, Osganian S. A school nurse-delivered intervention for overweight and obese adolescents. J Sch Health. 2013 Mar; 83(3):182-93.
  10. Austin SB, Richmond TK, Spadano-Gasbarro J, Greaney ML, Blood EA, Walls C, Wang ML, Mezgebu S, Osganian SK, Peterson KE. The contribution of school environmental factors to individual and school variation in disordered weight control behaviors in a statewide sample of middle schools. Eat Disord. 2013; 21(2):91-108.
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  12. Enquobahrie DA, Feldman HA, Hoelscher DH, Steffen LM, Webber LS, Zive MM, Rimm EB, Stampfer MJ, Osganian SK. Serum homocysteine and folate concentrations among a US cohort of adolescents before and after folic acid fortification. Public Health Nutr. 2012 Oct; 15(10):1818-26.
  13. Ebbeling CB, Feldman HA, Chomitz VR, Antonelli TA, Gortmaker SL, Osganian SK, Ludwig DS. A randomized trial of sugar-sweetened beverages and adolescent body weight. N Engl J Med. 2012 Oct 11; 367(15):1407-16.
  14. Lee LK, Walia T, Forbes PW, Osganian SK, Samuels R, Cox JE, Mooney DP. Home safety practices in an urban low-income population: level of agreement between parental self-report and observed behaviors. Clin Pediatr (Phila). 2012 Dec; 51(12):1119-24.
  15. Howe CA, Freedson PS, Alhassan S, Feldman HA, Osganian SK. A recess intervention to promote moderate-to-vigorous physical activity. Pediatr Obes. 2012 Feb; 7(1):82-8.
  16. Austin SB, Spadano-Gasbarro JL, Greaney ML, Blood EA, Hunt AT, Richmond TK, Wang ML, Mezgebu S, Osganian SK, Peterson KE. Effect of the planet health intervention on eating disorder symptoms in Massachusetts middle schools, 2005-2008. Prev Chronic Dis. 2012; 9:E171; quiz E171.
  17. Pbert L, Druker S, DiFranza JR, Gorak D, Reed G, Magner R, Sheetz AH, Osganian S. Effectiveness of a school nurse-delivered smoking-cessation intervention for adolescents. Pediatrics. 2011 Nov; 128(5):926-36.
  18. Gellar L, Druker S, Osganian SK, Gapinski MA, Lapelle N, Pbert L. Exploratory research to design a school nurse-delivered intervention to treat adolescent overweight and obesity. J Nutr Educ Behav. 2012 Jan-Feb; 44(1):46-54.
  19. de Ferranti SD, Crean S, Cotter J, Boyd D, Osganian SK. Hypertriglyceridemia in a pediatric referral practice: experience with 300 patients. Clin Pediatr (Phila). 2011 Apr; 50(4):297-307.
  20. Austin SB, Spadano-Gasbarro J, Greaney ML, Richmond TK, Feldman HA, Osganian SK, Hunt AT, Mezgebu S, Peterson KE. Disordered weight control behaviors in early adolescent boys and girls of color: an under-recognized factor in the epidemic of childhood overweight. J Adolesc Health. 2011 Jan; 48(1):109-12.
  21. Howe CA, Freedson PS, Feldman HA, Osganian SK. Energy expenditure and enjoyment of common children's games in a simulated free-play environment. J Pediatr. 2010 Dec; 157(6):936-942.e1-2.
  22. Gray SH, Ebe LK, Feldman HA, Emans SJ, Osganian SK, Gordon CM, Laufer MR. Salivary progesterone levels before menarche: a prospective study of adolescent girls. J Clin Endocrinol Metab. 2010 Jul; 95(7):3507-11.
  23. Suchy FJ, Brannon PM, Carpenter TO, Fernandez JR, Gilsanz V, Gould JB, Hall K, Hui SL, Lupton J, Mennella J, Miller NJ, Osganian SK, Sellmeyer DE, Wolf MA. National Institutes of Health Consensus Development Conference: lactose intolerance and health. Ann Intern Med. 2010 Jun 15; 152(12):792-6.
  24. Suchy FJ, Brannon PM, Carpenter TO, Fernandez JR, Gilsanz V, Gould JB, Hall K, Hui SL, Lupton J, Mennella J, Miller NJ, Osganian SK, Sellmeyer DE, Wolf MA. NIH consensus development conference statement: Lactose intolerance and health. NIH Consens State Sci Statements. 2010 Feb 24; 27(2):1-27.
  25. Gordon MB, Osganian SK, Emans SJ, Lovejoy FH. Gender differences in research grant applications for pediatric residents. Pediatrics. 2009 Aug; 124(2):e355-61.
  26. De Ferranti SD, Osganian SK. Epidemiology of paediatric metabolic syndrome and type 2 diabetes mellitus. Diab Vasc Dis Res. 2007 Dec; 4(4):285-96.
  27. Poussaint TY, Phillips PC, Vajapeyam S, Fahey FH, Robertson RL, Osganian S, Ramamurthy U, Mulkern RV, Treves ST, Boyett JM, Kun LE. The Neuroimaging Center of the Pediatric Brain Tumor Consortium-collaborative neuroimaging in pediatric brain tumor research: a work in progress. AJNR Am J Neuroradiol. 2007 Apr; 28(4):603-7.
  28. Reaves L, Steffen LM, Dwyer JT, Webber LS, Lytle LA, Feldman HA, Hoelscher DM, Zive MM, Osganian SK. Vitamin supplement intake is related to dietary intake and physical activity: The Child and Adolescent Trial for Cardiovascular Health (CATCH). J Am Diet Assoc. 2006 Dec; 106(12):2018-23.
  29. Pbert L, Osganian SK, Gorak D, Druker S, Reed G, O'Neill KM, Sheetz A. A school nurse-delivered adolescent smoking cessation intervention: a randomized controlled trial. Prev Med. 2006 Oct; 43(4):312-20.
  30. Lutsey PL, Steffen LM, Feldman HA, Hoelscher DH, Webber LS, Luepker RV, Lytle LA, Zive M, Osganian SK. Serum homocysteine is related to food intake in adolescents: the Child and Adolescent Trial for Cardiovascular Health. Am J Clin Nutr. 2006 Jun; 83(6):1380-6.
  31. Ebbeling CB, Feldman HA, Osganian SK, Chomitz VR, Ellenbogen SJ, Ludwig DS. Effects of decreasing sugar-sweetened beverage consumption on body weight in adolescents: a randomized, controlled pilot study. Pediatrics. 2006 Mar; 117(3):673-80.
  32. Cheifetz AT, Osganian SK, Allred EN, Needleman HL. Prevalence of bruxism and associated correlates in children as reported by parents. J Dent Child (Chic). 2005 May-Aug; 72(2):67-73.
  33. Fine AM, Forbes P, Osganian S, Goldmann DA, Mandl KD. Feasibility of leveraging electronic data from pediatric hospitals for national surveillance: a survey of chief information officers. AMIA Annu Symp Proc. 2005; 954.
  34. Hoelscher DM, Feldman HA, Johnson CC, Lytle LA, Osganian SK, Parcel GS, Kelder SH, Stone EJ, Nader PR. School-based health education programs can be maintained over time: results from the CATCH Institutionalization study. Prev Med. 2004 May; 38(5):594-606.
  35. Osganian SK, Hoelscher DM, Zive M, Mitchell PD, Snyder P, Webber LS. Maintenance of effects of the eat smart school food service program: results from the CATCH-ON study. Health Educ Behav. 2003 Aug; 30(4):418-33.
  36. Osganian SK, Parcel GS, Stone EJ. Institutionalization of a school health promotion program: background and rationale of the CATCH-ON study. Health Educ Behav. 2003 Aug; 30(4):410-7.
  37. Osganian SK, Stampfer MJ, Rimm E, Spiegelman D, Hu FB, Manson JE, Willett WC. Vitamin C and risk of coronary heart disease in women. J Am Coll Cardiol. 2003 Jul 16; 42(2):246-52.
  38. Rawson ES, Freedson PS, Osganian SK, Matthews CE, Reed G, Ockene IS. Body mass index, but not physical activity, is associated with C-reactive protein. Med Sci Sports Exerc. 2003 Jul; 35(7):1160-6.
  39. Osganian SK, Stampfer MJ, Rimm E, Spiegelman D, Manson JE, Willett WC. Dietary carotenoids and risk of coronary artery disease in women. Am J Clin Nutr. 2003 Jun; 77(6):1390-9.
  40. Osganian SK, Zapka JG, Feldman HA, Goldberg RJ, Hedges JR, Eisenberg MS, Raczynski JM, McGovern PG, Cooper LS, Pandey DK, Linares AC, Luepker RV. Use of emergency medical services for suspected acute cardiac ischemia among demographic and clinical patient subgroups: the REACT trial. Rapid Early Action for Coronary Treatment. Prehosp Emerg Care. 2002 Apr-Jun; 6(2):175-85.
  41. Kelder SH, Osganian SK, Feldman HA, Webber LS, Parcel GS, Leupker RV, Wu MC, Nader PR. Tracking of physical and physiological risk variables among ethnic subgroups from third to eighth grade: the Child and Adolescent Trial for Cardiovascular Health cohort study. Prev Med. 2002 Mar; 34(3):324-33.
  42. Goldberg RJ, Osganian S, Zapka J, Mitchell P, Bittner V, Daya M, Luepker R. Prehospital delay in individuals with acute coronary disease: concordance of medical records and follow-up phone interviews. Cardiology. 2002; 97(3):159-65.
  43. Bauchner H, Osganian S, Smith K, Triant R. Improving parent knowledge about antibiotics: a video intervention. Pediatrics. 2001 Oct; 108(4):845-50.
  44. Hedges JR, Feldman HA, Bittner V, Goldberg RJ, Zapka J, Osganian SK, Murray DM, Simons-Morton DG, Linares A, Williams J, Luepker RV, Eisenberg MS. Impact of community intervention to reduce patient delay time on use of reperfusion therapy for acute myocardial infarction: rapid early action for coronary treatment (REACT) trial. REACT Study Group. Acad Emerg Med. 2000 Aug; 7(8):862-72.
  45. Brown AL, Mann NC, Daya M, Goldberg R, Meischke H, Taylor J, Smith K, Osganian S, Cooper L. Demographic, belief, and situational factors influencing the decision to utilize emergency medical services among chest pain patients. Rapid Early Action for Coronary Treatment (REACT) study. Circulation. 2000 Jul 11; 102(2):173-8.
  46. Luepker RV, Raczynski JM, Osganian S, Goldberg RJ, Finnegan JR, Hedges JR, Goff DC, Eisenberg MS, Zapka JG, Feldman HA, Labarthe DR, McGovern PG, Cornell CE, Proschan MA, Simons-Morton DG. Effect of a community intervention on patient delay and emergency medical service use in acute coronary heart disease: The Rapid Early Action for Coronary Treatment (REACT) Trial. JAMA. 2000 Jul 5; 284(1):60-7.
  47. Goldberg R, Goff D, Cooper L, Luepker R, Zapka J, Bittner V, Osganian S, Lessard D, Cornell C, Meshack A, Mann C, Gilliland J, Feldman H. Age and sex differences in presentation of symptoms among patients with acute coronary disease: the REACT Trial. Rapid Early Action for Coronary Treatment. Coron Artery Dis. 2000 Jul; 11(5):399-407.
  48. Grenier MA, Osganian SK, Cox GF, Towbin JA, Colan SD, Lurie PR, Sleeper LA, Orav EJ, Lipshultz SE. Design and implementation of the North American Pediatric Cardiomyopathy Registry. Am Heart J. 2000 Feb; 139(2 Pt 3):S86-95.
  49. Goff DC, Feldman HA, McGovern PG, Goldberg RJ, Simons-Morton DG, Cornell CE, Osganian SK, Cooper LS, Hedges JR. Prehospital delay in patients hospitalized with heart attack symptoms in the United States: the REACT trial. Rapid Early Action for Coronary Treatment (REACT) Study Group. Am Heart J. 1999 Dec; 138(6 Pt 1):1046-57.
  50. Nader PR, Stone EJ, Lytle LA, Perry CL, Osganian SK, Kelder S, Webber LS, Elder JP, Montgomery D, Feldman HA, Wu M, Johnson C, Parcel GS, Luepker RV. Three-year maintenance of improved diet and physical activity: the CATCH cohort. Child and Adolescent Trial for Cardiovascular Health. Arch Pediatr Adolesc Med. 1999 Jul; 153(7):695-704.
  51. Osganian SK, Stampfer MJ, Spiegelman D, Rimm E, Cutler JA, Feldman HA, Montgomery DH, Webber LS, Lytle LA, Bausserman L, Nader PR. Distribution of and factors associated with serum homocysteine levels in children: Child and Adolescent Trial for Cardiovascular Health. JAMA. 1999 Apr 7; 281(13):1189-96.
  52. Simons-Morton DG, Goff DC, Osganian S, Goldberg RJ, Raczynski JM, Finnegan JR, Zapka J, Eisenberg MS, Proschan MA, Feldman HA, Hedges JR, Luepker RV. Rapid early action for coronary treatment: rationale, design, and baseline characteristics. REACT Research Group. Acad Emerg Med. 1998 Jul; 5(7):726-38.
  53. Stone EJ, Osganian SK, McKinlay SM, Wu MC, Webber LS, Luepker RV, Perry CL, Parcel GS, Elder JP. Operational design and quality control in the CATCH multicenter Trial. Prev Med. 1996 Jul-Aug; 25(4):384-99.
  54. Webber LS, Osganian SK, Feldman HA, Wu M, McKenzie TL, Nichaman M, Lytle LA, Edmundson E, Cutler J, Nader PR, Luepker RV. Cardiovascular risk factors among children after a 2 1/2-year intervention-The CATCH Study. Prev Med. 1996 Jul-Aug; 25(4):432-41.
  55. Osganian SK, Ebzery MK, Montgomery DH, Nicklas TA, Evans MA, Mitchell PD, Lytle LA, Snyder MP, Stone EJ, Zive MM, Bachman KJ, Rice R, Parcel GS. Changes in the nutrient content of school lunches: results from the CATCH Eat Smart Food service Intervention. Prev Med. 1996 Jul-Aug; 25(4):400-12.
  56. Osganian SK, Nicklas T, Stone E, Nichaman M, Ebzery MK, Lytle L, Nader PR. Perspectives on the School Nutrition Dietary Assessment Study from the Child and Adolescent Trial for Cardiovascular Health. Am J Clin Nutr. 1995 Jan; 61(1 Suppl):241S-244S.
  57. Johnson CC, Osganian SK, Budman SB, Lytle LA, Barrera EP, Bonura SR, Wu MC, Nader PR. CATCH: family process evaluation in a multicenter trial. Health Educ Q. 1994; Suppl 2:S91-106.
  58. McGraw SA, Stone EJ, Osganian SK, Elder JP, Perry CL, Johnson CC, Parcel GS, Webber LS, Luepker RV. Design of process evaluation within the Child and Adolescent Trial for Cardiovascular Health (CATCH). Health Educ Q. 1994; Suppl 2:S5-26.
  59. Raizman DJ, Montgomery DH, Osganian SK, Ebzery MK, Evans MA, Nicklas TA, Zive MM, Hann BJ, Snyder MP, Clesi AL. CATCH: food service program process evaluation in a multicenter trial. Health Educ Q. 1994; Suppl 2:S51-71.
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