Research

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Joseph Madsen, MD

joseph madsen
Department:
Neurosurgery Research
Hospital Title:
Director, Epilepsy Surgery Program;Associate in Neurosurgery
Academic Title:
Associate Professor of Neurosurgery, Harvard Medical School
Research Focus Area:
Epilepsy
Contact:
617-355-6008

Research Overview

As a neurosurgeon, one goal of Joseph Madsen's research is to combine clinical research and basic research -- using data from the former in the latter. For example, the study of human electrocorticograms recorded during behavioral cortical tasks is used to answer basic questions about cortical physiology. It is also used to point the way toward safer surgery to control epilepsy by improving the ability to map cortical function. This opportunity is uniquely available because of the need for and benefits of neurosurgical intervention. Advanced technologies, such as digital signal processing (DSP), wavelet analysis, and cutting-edge cognitive science combine in this new laboratory.

He and colleagues are also studying the role of electrostimulation of the vagal nerve in the treatment of epilepsy.

About Joseph Madsen

Joseph Madsen received his MD from Harvard Medical School and the Harvard-MIT Division of Health Sciences and Technology. He completed an internship at Beth Israel Deaconess Medical Center, a residency at Massachusetts General Hospital, and a fellowship at Beth Israel Deaconess Medical Center.

Key Publications

  • Scott RM, Madsen JR. Shunt technology: contemporary concepts and prospects. Clinical Neurosurgery 2003; 50:256-67.

  • Helmers SL, Wheless JW, Frost M, Gates J, Levisohn P, Tardo C, Conry JA, Yalnizoglu D, Madsen JR. Vagus nerve stimulation therapy in pediatric patients with refractory epilepsy: retrospective study. Journal of Child Neurology 2001; 16: 843848.

  • Lee IW, Vacanti JP, Taylor GA, Madsen JR. The living shunt: a tissue engineering approach in the treatment of hydrocephalus. Neurological Research 2000; 22: 105-10.

For a list of Joseph Madsen's publications on PubMed, click here.

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