Research

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Maureen Jonas, MD

Maureen Jonas
Department:
Medicine Research
Division
Gastroenterology, Hepatology and Nutrition Research
Hospital Title:
Senior Associate in Medicine
Academic Title:
Professor of Pediatrics, Harvard Medical School
Research Focus Area:
Liver disease
Contact:
617-355-5837

Research Overview

Maureen Jonas' research focuses on liver disease in children, with emphasis on viral hepatitis. She was the principal investigator in the multicenter International Pediatric Lamivudine Trial, and is currently studying the safety and efficacy of other drugs, adefovir dipivoxil and entecavir, in children with chronic hepatitis B. She is the principle site investigator for PEDS-C, an NIH sponsored study of the treatment of chronic hepatitis C in children. Other research involves looking at non-invasive ways to detect and measure fibrosis (scarring) in the liver, and some of the metabolic effects of chronic hepatitis C. She participates in an international epidemiologic study of hepatitis B in children, and the national Studies of Pediatric Liver Transplantation (SPLIT.)

About Maureen Jonas

Maureen Jonas received her MD degree from University of Miami School of Medicine. She completed internship and residency in General Pediatrics, and fellowship in Pediatric Gastroenterology, at Boston Children's Hospital. She is certified in Pediatric Gastroenterology and Pediatric Transplant Hepatology. Dr. Jonas has served on the Executive Council of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) and numerous committees of the American Association for the Study of Liver Diseases. She is a member of the Medical Advisory Committee of the New England Chapter of the American Liver Foundation. She is the director of the Center for Childhood Liver Disease and the Medical Director of the Liver Transplant Program at Boston Children’s Hospital. She is also the Director of the 4th year Advanced Hepatology Fellowship at Children’s. Dr. Jonas recently edited a book on Viral Hepatitis in Children.

Publications

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  1. Wasiak D, Jonas M, Lagiewska B, Cieciura T, Malkowski P, Chmura A. Delayed, Uncommon Recurrence of Hepatocellular Carcinoma After Liver Transplantation: A Case Report. Transplant Proc. 2016 Jun; 48(5):1855-7.
  2. Valentino PL, Jonas MM, Lee CK, Kim HB, Vakili K, Elisofon SA. Outcomes after discontinuation of routine use of transanastomotic biliary stents in pediatric liver transplantation at a single site. Pediatr Transplant. 2016 Aug; 20(5):647-51.
  3. Desai NK, Harney S, Raza R, Al-Ibraheemi A, Shillingford N, Mitchell PD, Jonas MM. Comparison of Controlled Attenuation Parameter and Liver Biopsy to Assess Hepatic Steatosis in Pediatric Patients. J Pediatr. 2016 Jun; 173:160-164.e1.
  4. Schwarz KB, Molleston JP, Jonas MM, Wen J, Murray KF, Rosenthal P, Gonzalez-Peralta RP, Lobritto SJ, Mogul D, Pavlovic V, Warne C, Wat C, Thompson B. Children Treated With Pegylated Interferon alfa-2a?±?Ribavirin for Chronic Hepatitis C. J Pediatr Gastroenterol Nutr. 2016 Jan; 62(1):93-6.
  5. Jonas MM, Lok AS, McMahon BJ, Brown RS, Wong JB, Ahmed AT, Farah W, Mouchli MA, Singh S, Prokop LJ, Murad MH, Mohammed K. Antiviral therapy in management of chronic hepatitis B viral infection in children: A systematic review and meta-analysis. Hepatology. 2016 Jan; 63(1):307-18.
  6. Terrault NA, Bzowej NH, Chang KM, Hwang JP, Jonas MM, Murad MH. AASLD guidelines for treatment of chronic hepatitis B. Hepatology. 2016 Jan; 63(1):261-83.
  7. Jonas MM, Chang MH, Sokal E, Schwarz KB, Kelly D, Kim KM, Ling SC, Rosenthal P, Oraseanu D, Reynolds L, Thiry A, Ackerman P. Randomized, controlled trial of entecavir versus placebo in children with hepatitis B envelope antigen-positive chronic hepatitis B. Hepatology. 2016 Feb; 63(2):377-87.
  8. Lee CK, Jonas MM. Hepatitis C: Issues in Children. Gastroenterol Clin North Am. 2015 Dec; 44(4):901-9.
  9. Tucker SM, Jonas MM, Perez-Atayde AR. Hyaline droplets in Kupffer cells: a novel diagnostic clue for autoimmune hepatitis. Am J Surg Pathol. 2015 Jun; 39(6):772-8.
  10. Wu FM, Jonas MM, Opotowsky AR, Harmon A, Raza R, Ukomadu C, Landzberg MJ, Singh MN, Valente AM, Egidy Assenza G, Perez-Atayde AR. Portal and centrilobular hepatic fibrosis in Fontan circulation and clinical outcomes. J Heart Lung Transplant. 2015 Jul; 34(7):883-91.
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  12. Delgado-Borrego A, Gonzalez-Peralta RP, Raza R, Negre B, Goodman ZD, Jonas MM, Chung RT, Ludwig DA. Correlates of adiponectin in hepatitis C-infected children: the importance of body mass index. J Pediatr Gastroenterol Nutr. 2015 Feb; 60(2):165-70.
  13. Jonas MM, Schwarz KB, Gonzalez-Peralta R, Lobritto S, Molleston JP, Murray KF, Rosenthal P, Wen J, Wat C, Pavlovic V, Warne C. Long-term growth outcomes in children treated for chronic hepatitis C. J Pediatr. 2014 Dec; 165(6):1252-4.
  14. Wu FM, Opotowsky AR, Raza R, Harney S, Ukomadu C, Landzberg MJ, Valente AM, Breitbart RE, Singh MN, Gauvreau K, Jonas MM. Transient elastography may identify Fontan patients with unfavorable hemodynamics and advanced hepatic fibrosis. Congenit Heart Dis. 2014 Sep-Oct; 9(5):438-47.
  15. Govender P, Jonas MM, Alomari AI, Padua HM, Dillon BJ, Landrigan-Ossar MF, Chaudry G. Sonography-guided percutaneous liver biopsies in children. AJR Am J Roentgenol. 2013 Sep; 201(3):645-50.
  16. Lee CK, Perez-Atayde AR, Mitchell PD, Raza R, Afdhal NH, Jonas MM. Serum biomarkers and transient elastography as predictors of advanced liver fibrosis in a United States cohort: the Boston children's hospital experience. J Pediatr. 2013 Oct; 163(4):1058-64.e2.
  17. Ramon-Krauel M, Salsberg SL, Ebbeling CB, Voss SD, Mulkern RV, Apura MM, Cooke EA, Sarao K, Jonas MM, Ludwig DS. A low-glycemic-load versus low-fat diet in the treatment of fatty liver in obese children. Child Obes. 2013 Jun; 9(3):252-60.
  18. Molleston JP, Mellman W, Narkewicz MR, Balistreri WF, Gonzalez-Peralta RP, Jonas MM, Lobritto SJ, Mohan P, Murray KF, Njoku D, Rosenthal P, Barton BA, Talor MV, Cheng I, Schwarz KB, Haber BA. Autoantibodies and autoimmune disease during treatment of children with chronic hepatitis C. J Pediatr Gastroenterol Nutr. 2013 Mar; 56(3):304-10.
  19. Jonas MM, Balistreri W, Gonzalez-Peralta RP, Haber B, Lobritto S, Mohan P, Molleston JP, Murray KF, Narkewicz MR, Rosenthal P, Schwarz KB, Barton BA, Shepherd JA, Mitchell PD, Duggan C. Pegylated interferon for chronic hepatitis C in children affects growth and body composition: results from the pediatric study of hepatitis C (PEDS-C) trial. Hepatology. 2012 Aug; 56(2):523-31.
  20. Delgado-Borrego A, Smith L, Jonas MM, Hall CA, Negre B, Jordan SH, Ogrodowicz M, Raza R, Ludwig DA, Miller T, Lipshultz SE, Gonzalez-Peralta R, Chung RT. Expected and actual case ascertainment and treatment rates for children infected with hepatitis C in Florida and the United States: epidemiologic evidence from statewide and nationwide surveys. J Pediatr. 2012 Nov; 161(5):915-21.
  21. Cauley RP, Suh MY, Kamin DS, Lillehei CW, Jenkins RL, Jonas MM, Vakili K, Kim HB. Multivisceral transplantation using a 2.9 kg neonatal donor. Pediatr Transplant. 2012 Dec; 16(8):E379-82.
  22. Jonas MM, Kelly D, Pollack H, Mizerski J, Sorbel J, Frederick D, Mondou E, Rousseau F, Sokal E. Efficacy and safety of long-term adefovir dipivoxil therapy in children with chronic hepatitis B infection. Pediatr Infect Dis J. 2012 Jun; 31(6):578-82.
  23. Kelly DA, Haber B, González-Peralta RP, Murray KF, Jonas MM, Molleston JP, Narkewicz MR, Sinatra FR, Lang T, Lachaux A, Wirth S, Shelton M, Te HS, Pollack H, Deng W, Noviello S, Albrecht JK. Durability of sustained response shown in paediatric patients with chronic hepatitis C who were treated with interferon alfa-2b plus ribavirin. J Viral Hepat. 2012 Apr; 19(4):263-70.
  24. Rodrigue JR, Balistreri W, Haber B, Jonas MM, Mohan P, Molleston JP, Murray KF, Narkewicz MR, Rosenthal P, Smith LJ, Lobritto SJ, Schwarz KB, Robuck PR, Barton B, González-Peralta RP. Peginterferon with or without ribavirin has minimal effect on quality of life, behavioral/emotional, and cognitive outcomes in children. Hepatology. 2011 May; 53(5):1468-75.
  25. Jonas MM. Hepatitis A virus infection: progress made, more work to be done. J Pediatr (Rio J). 2011 May-Jun 8; 87(3):185-6.
  26. Schwarz KB, Gonzalez-Peralta RP, Murray KF, Molleston JP, Haber BA, Jonas MM, Rosenthal P, Mohan P, Balistreri WF, Narkewicz MR, Smith L, Lobritto SJ, Rossi S, Valsamakis A, Goodman Z, Robuck PR, Barton BA. The combination of ribavirin and peginterferon is superior to peginterferon and placebo for children and adolescents with chronic hepatitis C. Gastroenterology. 2011 Feb; 140(2):450-458.e1.
  27. Jonas MM, Block JM, Haber BA, Karpen SJ, London WT, Murray KF, Narkewicz MR, Rosenthal P, Schwarz KB, McMahon BJ. Treatment of children with chronic hepatitis B virus infection in the United States: patient selection and therapeutic options. Hepatology. 2010 Dec; 52(6):2192-205.
  28. Delgado-Borrego A, Healey D, Negre B, Christofi M, Sabharwal S, Ludwig DA, Chung RT, Jonas MM. Influence of body mass index on outcome of pediatric chronic hepatitis C virus infection. J Pediatr Gastroenterol Nutr. 2010 Aug; 51(2):191-7.
  29. McGuire MM, Jones BA, Hull MA, Misra MV, Smithers CJ, Feins NR, Jenkins RL, Lillehei CW, Harmon WE, Jonas MM, Kim HB. Combined en bloc liver-double kidney transplantation in an infant with IVC thrombosis. Pediatr Transplant. 2011 Nov; 15(7):E142-4.
  30. Haber BA, Block JM, Jonas MM, Karpen SJ, London WT, McMahon BJ, Murray KF, Narkewicz MR, Rosenthal P, Schwarz KB. Recommendations for screening, monitoring, and referral of pediatric chronic hepatitis B. Pediatrics. 2009 Nov; 124(5):e1007-13.
  31. Rodrigue JR, Balistreri W, Haber B, Jonas MM, Mohan P, Molleston JP, Murray KF, Narkewicz MR, Rosenthal P, Smith LJ, Schwarz KB, Robuck P, Barton B, González-Peralta RP. Impact of hepatitis C virus infection on children and their caregivers: quality of life, cognitive, and emotional outcomes. J Pediatr Gastroenterol Nutr. 2009 Mar; 48(3):341-7.
  32. Jonas MM. Hepatitis B and pregnancy: an underestimated issue. Liver Int. 2009 Jan; 29 Suppl 1:133-9.
  33. Harmatz P, Jonas MM, Kwiatkowski JL, Wright EC, Fischer R, Vichinsky E, Giardina PJ, Neufeld EJ, Porter J, Olivieri N. Safety and efficacy of pegylated interferon alpha-2a and ribavirin for the treatment of hepatitis C in patients with thalassemia. Haematologica. 2008 Aug; 93(8):1247-51.
  34. Smith LM, Nesterova A, Ryan MC, Duniho S, Jonas M, Anderson M, Zabinski RF, Sutherland MK, Gerber HP, Van Orden KL, Moore PA, Ruben SM, Carter PJ. CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers. Br J Cancer. 2008 Jul 8; 99(1):100-9.
  35. Jonas MM, Kelly D, Pollack H, Mizerski J, Sorbel J, Frederick D, Mondou E, Rousseau F, Sokal E. Safety, efficacy, and pharmacokinetics of adefovir dipivoxil in children and adolescents (age 2 to &lt18 years) with chronic hepatitis B. Hepatology. 2008 Jun; 47(6):1863-71.
  36. Suh MY, Wang K, Gutweiler JR, Misra MV, Krawczuk LE, Jenkins RL, Lillehei CW, Jonas MM, Kim HB. Safety of minimal immunosuppression in liver transplantation for hepatoblastoma. J Pediatr Surg. 2008 Jun; 43(6):1148-52.
  37. Fong HF, Divasta AD, Difabio D, Ringelheim J, Jonas MM, Gordon CM. Prevalence and predictors of abnormal liver enzymes in young women with anorexia nervosa. J Pediatr. 2008 Aug; 153(2):247-53.
  38. Goodman ZD, Makhlouf HR, Liu L, Balistreri W, Gonzalez-Peralta RP, Haber B, Jonas MM, Mohan P, Molleston JP, Murray KF, Narkewicz MR, Rosenthal P, Smith LJ, Robuck PR, Schwarz KB. Pathology of chronic hepatitis C in children: liver biopsy findings in the Peds-C Trial. Hepatology. 2008 Mar; 47(3):836-43.
  39. Jonas MM, Little NR, Gardner SD. Long-term lamivudine treatment of children with chronic hepatitis B: durability of therapeutic responses and safety. J Viral Hepat. 2008 Jan; 15(1):20-7.
  40. Pall H, Zielenski J, Jonas MM, DaSilva DA, Potvin KM, Yuan XW, Huang Q, Freedman SD. Primary sclerosing cholangitis in childhood is associated with abnormalities in cystic fibrosis-mediated chloride channel function. J Pediatr. 2007 Sep; 151(3):255-9.
  41. Lee CK, Jonas MM. Pediatric hepatobiliary disease. Curr Opin Gastroenterol. 2007 May; 23(3):306-9.
  42. Modi BP, Suh MY, Jonas MM, Lillehei C, Kim HB. Ileal exclusion for refractory symptomatic cholestasis in Alagille syndrome. J Pediatr Surg. 2007 May; 42(5):800-5.
  43. Jonas MM. Finding adolescents and young adults with transfusion-associated hepatitis C: looking forward to looking back. Arch Pediatr Adolesc Med. 2007 Feb; 161(2):202-3.
  44. Neff GW, Kemmer N, Zacharias VC, Kaiser T, Duncan C, McHenry R, Jonas M, Novick D, Williamson C, Hess K, Thomas M, Buell J. Analysis of hospitalizations comparing rifaximin versus lactulose in the management of hepatic encephalopathy. Transplant Proc. 2006 Dec; 38(10):3552-5.
  45. Jonas MM. Treatment of chronic hepatitis B in children. J Pediatr Gastroenterol Nutr. 2006 Jul; 43 Suppl 1:S56-60.
  46. Squires RH, Shneider BL, Bucuvalas J, Alonso E, Sokol RJ, Narkewicz MR, Dhawan A, Rosenthal P, Rodriguez-Baez N, Murray KF, Horslen S, Martin MG, Lopez MJ, Soriano H, McGuire BM, Jonas MM, Yazigi N, Shepherd RW, Schwarz K, Lobritto S, Thomas DW, Lavine JE, Karpen S, Ng V, Kelly D, Simonds N, Hynan LS. Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr. 2006 May; 148(5):652-658.
  47. Elisofon SA, Jonas MM. Hepatitis B and C in children: current treatment and future strategies. Clin Liver Dis. 2006 Feb; 10(1):133-48, vii.
  48. Sokal EM, Kelly DA, Mizerski J, Badia IB, Areias JA, Schwarz KB, Vegnente A, Little NR, Gardener SD, Jonas MM. Long-term lamivudine therapy for children with HBeAg-positive chronic hepatitis B. Hepatology. 2006 Feb; 43(2):225-32.
  49. Berg CL, Jonas MM, Bacon BR. Treatment of hereditary hemochromatosis, Wilson Disease, and other metabolic disorders of the liver. Therapy in Digestive Diseases (MM Wolfe, ed.). 2006; 487-502.
  50. Elisofon SA, Jonas MM. Hepatitis B and C in Children: Current treatment and future strategies. Clinics in Liver Disease (J Bezerra and WF Balistreri, eds.). 2006; 10:133-148.
  51. Jonas MM. The role of liver transplantation in cystic fibrosis re-examined. Liver Transpl. 2005 Dec; 11(12):1463-5.
  52. Smektala R, Ohmann C, Paech S, Neuhaus E, Rieger M, Schwabe W, Debold P, Deimling A, Jonas M, Hupe K, Bücker-Nott HJ, Giani G, Szucs TD, Pientka L. [On the prognosis of hip fractures. Assessment of mortality after hip fractures by analyzing overlapping segments of longitudinal data]. Unfallchirurg. 2005 Nov; 108(11):927-8, 930-37.
  53. González-Peralta RP, Kelly DA, Haber B, Molleston J, Murray KF, Jonas MM, Shelton M, Mieli-Vergani G, Lurie Y, Martin S, Lang T, Baczkowski A, Geffner M, Gupta S, Laughlin M. Interferon alfa-2b in combination with ribavirin for the treatment of chronic hepatitis C in children: efficacy, safety, and pharmacokinetics. Hepatology. 2005 Nov; 42(5):1010-8.
  54. Kim HB, Pomposelli JJ, Lillehei CW, Jenkins RL, Jonas MM, Krawczuk LE, Fishman SJ. Mesogonadal shunts for extrahepatic portal vein thrombosis and variceal hemorrhage. Liver Transpl. 2005 Nov; 11(11):1389-94.
  55. Pall H, Jonas MM. Pediatric hepatobiliary disease. Curr Opin Gastroenterol. 2005 May; 21(3):344-7.
  56. Jonas MM, Krawczuk LE, Kim HB, Lillehei C, Perez-Atayde A. Rapid recurrence of nonalcoholic fatty liver disease after transplantation in a child with hypopituitarism and hepatopulmonary syndrome. Liver Transpl. 2005 Jan; 11(1):108-10.
  57. Broderick AM, Jonas MM. Management of hepatitis B infection in children. UpToDate (CD ROM) (BD Rose, ed.). 2005.
  58. Godra A, Jonas MM, Perez-Atayde AR. Histopathology of the liver in children with chronic hepatitis B (abstract). Modern Pathology. 2005; 18:312.
  59. Godra A, Perez-Atayde AR, Jonas MM. Histopathologic features of chronic hepatitis B in children (abstract). Hepatology. 2005; 42 (suppl):478-9(A).
  60. Riedlinger WFJ, Pall H, Jonas MM, Fox VL, Perez-Atayde AR. Primary sclerosing cholangitis: a clinicopathologic study in 31 children (abstract). Modern Pathology. 2005; 18:305.
  61. Jonas MM. Hepatitis C virus infectionin children. UpToDate (CD ROM) (BD Rose, ed.). 2005.
  62. Delgado-Borrego A, Jonas MM. Treatment Options for Hepatitis C Infection in Children. Curr Treat Options Gastroenterol. 2004 Oct; 7(5):373-379.
  63. Chang MH, Hadzic D, Rouassant SH, Jonas M, Kohn IJ, Negro F, Roberts E, Sibal A. Acute and chronic hepatitis: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2004 Jun; 39 Suppl 2:S584-8.
  64. Hom X, Little NR, Gardner SD, Jonas MM. Predictors of virologic response to Lamivudine treatment in children with chronic hepatitis B infection. Pediatr Infect Dis J. 2004 May; 23(5):441-5.
  65. Broderick A, Jonas MM. Management of hepatitis B in children. Clin Liver Dis. 2004 May; 8(2):387-401.
  66. Jonas MM. Nonalcoholic fatty liver disease. Adolesc Med Clin. 2004 Feb; 15(1):159-73, xi.
  67. Mayer A, Jonas MM. Hepatitis C. Textbook of Pediatric Infectious Diseases (RD Feigin, JD Cherry, GJ Demmler, and S Kaplan, eds.). 2004; 2237-51.
  68. Broderick A, Jonas MM. Hepatitis B and Hepatitis D. Textbook of Pediatric Infectious Diseases (RD Feigin, JD Cherry, GJ Demmler, and S Kaplan, eds.). 2004; 1863-83.
  69. Jonas MM. Hepatitis C in Children. Management Issues in Hepatitis C Infection (JG McHutchison ed.). 2004; 104-7.
  70. Jonas MM. Hepatitis C in Children. Hepatol Rev. 2004; 1:32-8.
  71. Broderick A, Jonas MM. Management of Hepatitis B in Children. Clinics in Liver Disease (TT Tran and P Martin, eds.). 2004; 387-401.
  72. Chang M-W, Hadzic D, Heller S, Jonas M, Kohn IJ, Negro F, Roberts E, Sibal A. Working Group Report on Acute and Chronic Hepatitis. J Pediatr Gastroenterol Nutr. 2004; 39:S584-8.
  73. Yuan Q, Jonas MM. Pediatric hepatobiliary disease. Curr Opin Gastroenterol. 2003 May; 19(3):276-80.
  74. Broderick AL, Jonas MM. Hepatitis B in children. Semin Liver Dis. 2003 Feb; 23(1):59-68.
  75. Jonas MM (Section Editor). Hepatobilary System. Rudolph's Pediatrics (C Rudolph, ed.). 2003; 1469-1518.
  76. Jonas MM, Perez-Atayde AR. Liver Disease in Infancy and Childhood. Diseases of the Liver (ER Schiff and M Sorell, eds.). 2003; 1459-98.
  77. Jonas MM. Children with hepatitis C. Hepatology. 2002 Nov; 36(5 Suppl 1):S173-8.
  78. Jonas MM. Re: ganciclovir treatment in infants with cytomegalovirus infection and cholestasis. J Pediatr Gastroenterol Nutr. 2002 Sep; 35(3):399-400; author reply 400.
  79. Jonas MM. Concerns about experimental design. J Pediatr Gastroenterol Nutr. 2002 Aug; 35(2):234.
  80. Jonas MM, Kelley DA, Mizerski J, Badia IB, Areias JA, Schwarz KB, Little NR, Greensmith MJ, Gardner SD, Bell MS, Sokal EM. Clinical trial of lamivudine in children with chronic hepatitis B. N Engl J Med. 2002 May 30; 346(22):1706-13.
  81. Jonas MM. Children with Hepatitis C. Hepatology (Proceedings of NIH Consensus Conference on Hepatitis C). 2002; 36 (Suppl):S173-8.
  82. Razvi S, Schneider L, Jonas MM, Cunningham-Rundles C. Outcome of intravenous immunoglobulin-transmitted hepatitis C virus infection in primary immunodeficiency. Clin Immunol. 2001 Dec; 101(3):284-8.
  83. Jonas MM. Challenges in the treatment of hepatitis C in children. Clin Liver Dis. 2001 Nov; 5(4):1063-71.
  84. Jonas M, Scholefield JH. Anal Fissure. Gastroenterol Clin North Am. 2001 Mar; 30(1):167-81.
  85. Burns JL, Griffith A, Barry JJ, Jonas M, Chi EY. Transcytosis of gastrointestinal epithelial cells by Escherichia coli K1. Pediatr Res. 2001 Jan; 49(1):30-7.
  86. Jonas MM, Graeme-Cook FM. A 17-year-old girl with vomiting, jaundice and weight loss. Case records of the Massachusetts General Hospital. N Engl J Med. 2001; 344:591-9.
  87. Jonas MM, Perez-Atayde AR. Fibrocystic Liver Diseases. Liver Disease in Children (FJ Suchy, RJ Sokol, and WF Balistreri, eds.). 2001; 899-913.
  88. Nguyen D, Buonomo C, Jonas M. Image of the month. Diagnosis of cutis laxa. Gastroenterology. 2000 Dec; 119(6):1430;1804.
  89. Jonas MM. Viral hepatitis. From prevention to antivirals. Clin Liver Dis. 2000 Nov; 4(4):849-77.
  90. Berg CL, Jonas MM, Gollan JL. Treatment of genetic hemochromatosis, Wilson Disease, and other metabolic diseases of the liver. Therapy of Digestive Disorders (MM Wolfe, ed.). 2000; 257-88.
  91. Jonas MM. Hepatitis C in Children. Hepatitis C (TJ Liang and JH Hoofnagle, eds.). 2000; 389-403.
  92. Jonas MM. Viral Hepatitis- From Prevention to Antivirals. Clinics in Liver Disease (JA Bezerra and WF Balistreri, eds.). 2000; 849-77.
  93. Hom XB, Jonas MM. Sources of viral hepatitis in children. Viral Hepatitis Rev. 2000; 6:47-64.
  94. Jonas MM. Treatment of chronic hepatitis C in pediatric patients. Clin Liver Dis. 1999 Nov; 3(4):855-67.
  95. Jonas MM. Hepatitis C infection in children. N Engl J Med. 1999 Sep 16; 341(12):912-3.
  96. Varela-Fascinetto G, Treacy SJ, Lillehei CW, Jonas MM, Lund DP, Kevy SV, Pérez A, Zurakowski D, Vacanti JP. Long-term results in pediatric ABO-incompatible liver transplantation. Transplant Proc. 1999 Feb-Mar; 31(1-2):467-8.
  97. Linton RA, Turtle M, Band DM, O'Brien TK, Jonas MM, Linton NW. A new technique for measuring cardiac output and shunt fraction during venovenous extracorporeal membrane oxygenation. Perfusion. 1999 Jan; 14(1):43-7.
  98. Siafakas C, Jonas MM. Neonatal Hepatitis. Pediatric Gastrointestinal Disease: Pathophysiology, Diagnosis, Management. 1999; 553-67.
  99. Smith S, Skerrett SJ, Chi EY, Jonas M, Mohler K, Wilson CB. The locus of tumor necrosis factor-alpha action in lung inflammation. Am J Respir Cell Mol Biol. 1998 Dec; 19(6):881-91.
  100. Siafakas CG, Jonas MM, Alexander S, Herrin J, Furuta GT. Early onset of nephrotic syndrome after treatment with D-penicillamine in a patient with Wilson's disease. Am J Gastroenterol. 1998 Dec; 93(12):2544-6.
  101. Teitelbaum JE, Perez-Atayde AR, Cohen M, Bousvaros A, Jonas MM. Minocycline-related autoimmune hepatitis: case series and literature review. Arch Pediatr Adolesc Med. 1998 Nov; 152(11):1132-6.
  102. Badizadegan K, Jonas MM, Ott MJ, Nelson SP, Perez-Atayde AR. Histopathology of the liver in children with chronic hepatitis C viral infection. Hepatology. 1998 Nov; 28(5):1416-23.
  103. Winram SB, Jonas M, Chi E, Rubens CE. Characterization of group B streptococcal invasion of human chorion and amnion epithelial cells In vitro. Infect Immun. 1998 Oct; 66(10):4932-41.
  104. Srivastava M, Perez-Atayde A, Jonas MM. Drug-associated acute-onset vanishing bile duct and Stevens-Johnson syndromes in a child. Gastroenterology. 1998 Sep; 115(3):743-6.
  105. Kim SZ, Marz PL, Laor T, Teitelbaum J, Jonas MM, Levy HL. Elevated galactose in newborn screening due to congenital absence of the portal vein. Eur J Pediatr. 1998 Jul; 157(7):608-9.
  106. Jonas MM, Ott MJ, Nelson SP, Badizadegan K, Perez-Atayde AR. Interferon-alpha treatment of chronic hepatitis C virus infection in children. Pediatr Infect Dis J. 1998 Mar; 17(3):241-6.
  107. Laor T, Hoffer FA, Vacanti JP, Jonas MM. MR cholangiography in children after liver transplantation from living related donors. AJR Am J Roentgenol. 1998 Mar; 170(3):683-7.
  108. Linton R, Turtle M, Band D, O'Brien T, Jonas M. In vitro evaluation of a new lithium dilution method of measuring cardiac output and shunt fraction in patients undergoing venovenous extracorporeal membrane oxygenation. Crit Care Med. 1998 Jan; 26(1):174-7.
  109. Darmstadt GL, Fleckman P, Jonas M, Chi E, Rubens CE. Differentiation of cultured keratinocytes promotes the adherence of Streptococcus pyogenes. J Clin Invest. 1998 Jan 1; 101(1):128-36.
  110. Murray KF, Jonas MM. Biliary Atresia. Clinical Pediatric Gastroenterology (S Altschuler and C Liacouras, eds.). 1998; 331-9.
  111. Nizet V, Kim KS, Stins M, Jonas M, Chi EY, Nguyen D, Rubens CE. Invasion of brain microvascular endothelial cells by group B streptococci. Infect Immun. 1997 Dec; 65(12):5074-81.
  112. Lenders C, Buonomo C, Jonas MM. Image of the month. Disseminated infections, especially candidiasis in immunocompromised individuals, cat-scratch fever, and infiltrative diseases such as leukemia or lymphoma. Gastroenterology. 1997 Nov; 113(5):1432, 1815.
  113. Siafakas CG, Jonas MM, Perez-Atayde AR. Abnormal bile acid metabolism and neonatal hemochromatosis: a subset with poor prognosis. J Pediatr Gastroenterol Nutr. 1997 Sep; 25(3):321-6.
  114. Jonas MM, Robertson LM, Middleman AB. Low prevalence of antibody to hepatitis C virus in an urban adolescent population. J Pediatr. 1997 Aug; 131(2):314-6.
  115. Bresee JS, Mast EE, Coleman PJ, Baron MJ, Schonberger LB, Alter MJ, Jonas MM, Yu MY, Renzi PM, Schneider LC. Hepatitis C virus infection associated with administration of intravenous immune globulin. A cohort study. JAMA. 1996 Nov 20; 276(19):1563-7.
  116. Schluger LK, Sheiner PA, Jonas M, Guarrera JV, Fiel IM, Meyers B, Berk PD. Isoniazid hepatotoxicity after orthotopic liver transplantation. Mt Sinai J Med. 1996 Oct-Nov; 63(5-6):364-9.
  117. Burns JL, Jonas M, Chi EY, Clark DK, Berger A, Griffith A. Invasion of respiratory epithelial cells by Burkholderia (Pseudomonas) cepacia. Infect Immun. 1996 Oct; 64(10):4054-9.
  118. Jonas MM. Interferon-alpha for viral hepatitis. J Pediatr Gastroenterol Nutr. 1996 Aug; 23(2):93-106.
  119. Jonas MM, Baron MJ, Bresee JS, Schneider LC. Clinical and virologic features of hepatitis C virus infection associated with intravenous immunoglobulin. Pediatrics. 1996 Aug; 98(2 Pt 1):211-5.
  120. Shamberger RC, Leichtner AM, Jonas MM, LaQuaglia MP. Long-term hepatic regeneration and function in infants and children following liver resection. J Am Coll Surg. 1996 Jun; 182(6):515-9.
  121. Nelson SP, Jonas MM. Hepatitis C infection in children who received extracorporeal membrane oxygenation. J Pediatr Surg. 1996 May; 31(5):644-8.
  122. Fishman LN, Jonas MM, Lavine JE. Update on viral hepatitis in children. Pediatr Clin North Am. 1996 Feb; 43(1):57-74.
  123. Jonas MM. Hepatitis C virus infection: clinical aspects and treatment with interferon alfa. Clin Ther. 1996; 18 Suppl B:110-25.
  124. Schneider LC, Jonas MM, Baron MJ, Mast EF, Alter MJ, Schonberger LB, Lambert S, Coleman P, Bresee JS. Intravenous immunoglobulin and hepatitis C virus: the Boston episode. Clin Ther. 1996; 18 Suppl B:108-9.
  125. Nelson SN, Jonas MM. Clinical features of liver disease. Practical Pediatric Gastroenterology (JA Walker-Smith, JR Hamilton, and WA Walker, eds.). 1996; 107-18.
  126. Jonas MM. Hepatitis C virus infection: clinical aspects and treatment with interferon-alfa. Clin Therapeut. 1996; 18 (Suppl):110-25.
  127. Jonas MM. Hepatitis B vaccination in pediatric practice. Infectious Disease in Children. 1996; 7-13.
  128. Jonas MM. Viral hepatitis. Pediatric Gastrointestinal Disease (WA Walker, PR Durie, JR Hamilton, JA Walker-Smith, and JB Watkins, eds.). 1996; 1028-51.
  129. Jonas MM. The clinical spectrum of hepatitis C virus infection. Internat Semin Paediatr Gastroenterol Nutr. 1996; 5:9-15.
  130. Wagstaff J, Jonas MM. Closing in on a "familial cholestasis gene". Hepatology. 1995 Nov; 22(5):1611-3.
  131. Miller TL, Jonas MM. Adolescent Human Immunodeficiency Virus Infection and Gastrointestinal Disease. Adolesc Med. 1995 Oct; 6(3):397-416.
  132. Jonas MM. Hereditary hemorrhagic telangiectasia. J Pediatr Gastroenterol Nutr. 1995 Feb; 20(2):238.
  133. D'Agata ID, Jonas MM. Shedding light into the black box of childhood cholestatic liver disease. Hepatology. 1995 Jan; 21(1):257-60.
  134. D'Agata ID, Jonas MM, Perez-Atayde AR, Guay-Woodford LM. Combined cystic disease of the liver and kidney. Semin Liver Dis. 1994 Aug; 14(3):215-28.
  135. Bross DA, Perez-Atayde A, Mandell VS, Hyams JS, Jonas MM. Hereditary hemorrhagic telangiectasia presenting in early childhood. J Pediatr Gastroenterol Nutr. 1994 May; 18(4):497-500.
  136. Perez-Atayde AR, Sirlin SM, Jonas M. Coombs-positive autoimmune hemolytic anemia and postinfantile giant cell hepatitis in children. Pediatr Pathol. 1994 Jan-Feb; 14(1):69-77.
  137. Jonas MM, R Siegel. Hepatitis B infection in Children. AAP Pediatric Update (monograph and audiocassette) (WF Balistreri, moderator). 1994.
  138. Powelson JA, Cosimi AB, Lewis WD, Rohrer RJ, Freeman RB, Vacanti JP, Jonas M, Lorber MI, Marks WH, Bradley J, et al. Hepatic retransplantation in New England--a regional experience and survival model. Transplantation. 1993 Apr; 55(4):802-6.
  139. Jonas MM, Walker WA. Disorders of the biliary tree. Gellis and Kagan's Current Pediatric Therapy (FD Burg, J Ingelfinger, and E Wald, eds.). 1993.
  140. Jonas MM. Bacterial overgrowth in the small bowel. Pediatric Gastrointestinal Disease: Pathophysiology, Diagnosis, Management (R Wyllie and J Hyams, eds.). 1993.
  141. Jonas MM, Zilleruelo GE, LaRue SI, Abitbol C, Strauss J, Lu Y. Hepatitis C infection in a pediatric dialysis population. Pediatrics. 1992 Apr; 89(4 Pt 2):707-9.
  142. Jonas MM, Bell MD, Eidson MS, Koutouby R, Hensley GT. Congenital diabetes mellitus and fatal secretory diarrhea in two infants. J Pediatr Gastroenterol Nutr. 1991 Nov; 13(4):415-25.
  143. Jonas MM, Ragin L, Silva MO. Membranous glomerulonephritis and chronic persistent hepatitis B in a child: treatment with recombinant interferon alfa. J Pediatr. 1991 Nov; 119(5):818-20.
  144. Ranjan D, Purser R, Jonas M, Yrizzary J, Borgeson M, Miller J, Burke G. Isolated splenic vein thrombosis as a cause of massive upper-gastrointestinal bleeding following orthotopic liver transplantation. Transplantation. 1991 Oct; 52(4):725-7.
  145. Sachse RE, Burke GW, Jonas M, Milgrom M, Miller J. Benign pneumatosis intestinalis with subcutaneous emphysema in a liver transplant recipient. Am J Gastroenterol. 1990 Jul; 85(7):876-9.
  146. Jonas MM, Reddy RK, DeMedina M, Schiff ER. Hepatitis B infection in a large municipal obstetrical population: characterization and prevention of perinatal transmission. Am J Gastroenterol. 1990 Mar; 85(3):277-80.
  147. Burke GW III, Ranjan D, Jonas MM, Koleilat N, Miller J. Current trends in immunosuppression in pediatric orthotopic liver transplantation. Internat Pediatr. 1990; 5:18-22.
  148. Jonas MM, Roldan EO, Lyons HJ, Fojaco RM, Reddy RK. Histopathologic features of the liver in pediatric acquired immune deficiency syndrome. J Pediatr Gastroenterol Nutr. 1989 Jul; 9(1):73-81.
  149. Jonas MM. Gastrointestinal disease symptoms. Curr Opin Pediatr. 1989; 1:345-9.
  150. Jayachandar J, Frank JL, Jonas MM. Isolated intestinal myopathy resembling progressive systemic sclerosis in a child. Gastroenterology. 1988 Oct; 95(4):1114-8.
  151. Jonas MM, Eidson MS. Propylthiouracil hepatotoxicity: two pediatric cases and review of the literature. J Pediatr Gastroenterol Nutr. 1988 Sep-Oct; 7(5):776-9.
  152. Jonas MM, Kaweblum YA, Fojaco R. Neonatal hemochromatosis: failure of deferoxamine therapy. J Pediatr Gastroenterol Nutr. 1987 Nov-Dec; 6(6):984-8.
  153. Jonas MM, Schiff ER, O'Sullivan MJ, de Medina M, Reddy KR, Jeffers LJ, Fayne T, Roach KC, Steele BW. Failure of Centers for Disease Control criteria to identify hepatitis B infection in a large municipal obstetrical population. Ann Intern Med. 1987 Sep; 107(3):335-7.
  154. Jonas MM. Inflammatory bowel disease in children and adolescents. Pract Gastroenterol. 1987; 11:37-42.
  155. Jonas MM, Montgomery RK, Grand RJ. Intestinal lactase synthesis during postnatal development in the rat. Pediatr Res. 1985 Sep; 19(9):956-62.
  156. Jonas MM, Grand RJ. The abdomen and gastrointestinal tract (sections). Pediatrics (M Ziai, ed.). 1984; 292-4.
  157. Jonas MM, Perrault J, Grand RJ, Dickson ER. Clinical response to penicillamine in cholestatic liver disease. Extrahepatic biliary atresia (F Daum, ed.). 1983; 227-32.
  158. Montgomery RK, Jonas MM, Grand RJ. Intestinal disaccharidases: structure, function and deficiency. Carbohydrate intolerance in infancy (F Lifshitz, ed.). 1982; 75-92.
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