The goals of Jonathan Finkelstein's research are to:
- Promote judicious antibiotic use in primary care practice.
- Measure trends in community antibiotic resistance among key pathogens.
- Develop new research methods and infrastructure to measure and improve the quality of care for children.
His research has included a wide range of epidemiologic studies of disease burden in defined populations. He has also conducted cluster-randomized behavior change intervention trials for both providers and patients to improve asthma care and to promote more judicious antibiotic prescribing. Currently, he leads a decade-long longitudinal study of antibiotic resistance in eight Massachusetts communities.
About Jonathan Finkelstein, MD, MPH
Jonathan Finkelstein received his MD from the University of Pennsylvania School of Medicine and his MPH from Harvard School of Public Health. He completed an internship, residency and fellowship at Boston Children's Hospital. Dr. Finkelstein is the Vice Chair for Quality and Outcomes and holds the Donald M. Berwick Chair in Pediatric Quality and Outcomes at Boston Children’s Hospital. He co-directs a training program for pediatric health services researchers and teaches extensively at Harvard Medical School.
- Finkelstein JA, Stille C, Nordin J, Davis R, Raebel MA, Roblin D, Go A, Smith D, Johnson CC, Kleinman K, Chan KA, Platt R. Reduction in antibiotic use among US children, 1996-2000. Pediatrics. 2003;112(3 pt 1):620-627.
- Finkelstein JA, Huang SS, Daniel J, Rifas-Shiman, SL, Kleinman K, Goldmann D, Pelton S, DeMaria A, Platt R. Antibiotic-resistant streptococcus pneumoniae in the PCV7 era: predictors of carriage in a multi-community sample. Pediatrics. 2003;112(4):862-869.
- Lozano P, Finkelstein JA, Carey VJ, Wagner EH, Inui TS, Fuhlbrigge AL, Soumerai SB, Sullivan SD, Weiss ST, Weiss KB. A multi-site randomized trial of the effects of physician education and organizational change in chronic asthma care: health outcomes of the Pediatric Asthma Care PORT study. Arch Pediatr Adolesc Med. 2004;158(9):875-883.
- Finkelstein JA, Lozano P, Fuhlbrigge AL, Carey VJ, Inui TS, Soumerai SB, Sullivan SD, Wagner EH, Weiss ST, Weiss KB. Practice-level effects of interventions to improve asthma care in primary care settings: the Pediatric Asthma Care PORT. Health Serv Res. 2005;40(6 Pt 1):1737-1757.
- Kappelman MD, Bousvaros A, Hyams J, Markowitz J, Pfefferkorn M, Kugathasan S, Rosh J, Otley A, Mack D, Griffiths A, Evans J, Grand R, Langton C, Kleinman K, Finkelstein JA. Intercenter variation in initial management of children with Crohn’s disease. Inflamm Bowel Dis. 2007;13(7):890-895.
- Finkelstein JA, Huang SS, Kleinman K, Rifas-Shiman SL, Stille CJ, Daniel J, Schiff N, Steingard R, Soumerai SB, Ross-Degnan D, Goldmann D, Platt R. Impact of a 16-community trial to promote judicious antibiotic use in Massachusetts. Pediatrics. 2008;121(1):e15-23.
- Hanage WP, Bishop CJ, Huang SS, Stevenson AE, Pelton SI, Lipsitch M, Finkelstein JA. Carried pneumococci in Massachusetts children; the contribution of clonal expansion and serotype switching. Pediatr Infect Dis J. 2011;30(4):302-308. PMCID: PMC3175614.
- Greene SK, Kleinman KP, Lakoma MD, Rifas-Shiman SL, Lee GM, Huang SS, Finkelstein JA. Trends in antibiotic use in Massachusetts children, 2000-2009. Pediatrics. 2012;130(1):15-22. PMCID: PMC3382917.
- Garvey KG, Wolpert HA, Rhodes ET, Laffel LM, Kleinman K, Beste MG, Wolfsdorf JI, Finkelstein JA. Health care transition in patients with type 1 diabetes mellitus: young adult experiences and relationship to glycemic control diabetes care. Diabetes Care. 2012;35(8):1716-22. PMCID: PMC3402251.
- Lee GM, Kleinman K, Pelton SI, Hanage W, Huang SS, Lakoma M, Dutta-Linn M, Croucher NJ, Stevenson A, Finkelstein JA. Impact of PCV13 vaccination on Streptococcus pneumoniae carriage in young children in Massachusetts. J Ped Infec Dis. 2014;3(1):23-32. PMCID: PMC3933044.
2010-2015 Conjugate vaccine impact on pneumococcal carriage, disease, and population genetics
NIH-NIAID 2 R01 AI066304-05
This research continues the examination of trends in pneumococcal colonizing and invasive disease isolates, will assess shifts in pneumococcal population structure by MLST, and use whole genome sequencing to identify potential genetic determinants associated with serotype switching and invasiveness.
2010-2015 Emerging trends in antimicrobial use and their impact on primary care for children
This mid-career development award allows investigation of antibiotic use trends using data from 3 health plans, as well as conducting a parent survey regarding current views of antibiotic use among the general public. It also allows Dr. Finkelstein to focus additional effort on mentorship activities in his roles as a research fellowship director.
2013-2018 Research Training in Prevention and Care of Chronic Illness in Childhood
This NRSA program supports training for researchers to study prevention and care delivery for children, particularly those with chronic conditions. It will include research on childhood risk factors for disease; and methods to transform health systems to deliver more effective, coordinated care. The program will support trainee stipends and tuition at the Harvard School of Public Health, and other fellowship expenses.
2013-2018 Training in child health services research and implementation science
This grant supports an NRSA post-doctoral fellowship program for health services researchers across pediatric subspecialties with a focus on training in implementation science. The program will support trainee stipends and tuition at the Harvard School of Public Health, and other fellowship expenses.