Research

LIke ThisLIke ThisLIke This

Richard  Bachur, MD

Richard Bachur MD
Department:
Medicine Research
Division
Emergency Medicine Research
Hospital Title:
Chief, Division of Emergency Medicine; Senior Physician in Medicine
Academic Title:
Professor, Harvard Medical School
Research Focus Area:
AppendicitisInfectious Disease Emergencies
Contact Via Email
Send an email to SendYour Name*Your Email Address*Subject*Comments*

Research Overview

Dr. Bachur’s major research interests include the diagnostic evaluation of common presenting conditions including urinary tract infection, pneumonia, bacteremia, and appendicitis.

About Richard Bachur

Rich Bachur obtained his medical degree from UCLA before his clinical training in pediatrics and pediatric emergency medicine (Boston Children’s Hospital). He joined the faculty in 1994, was the fellowship director from 2003-2010, became chief of the Division of Emergency Medicine in 2009, and was promoted to Professor in 2015.

Key Publications


Bachur R, Perry H, Harper MB. Occult pneumonias: empiric chest radiographs in febrile children with leukocytosis. Ann Emerg Med. Feb 1999;33(2):166-173.
Bachur R, Harper MB. Reevaluation of outpatients with Streptococcus pneumoniae bacteremia. Pediatrics. Mar 2000;105(3 Pt 1):502-509.
• Kentsis A, Lin YY, Kurek K, Calicchio M, Wang L, Monigatti F, Campagne F, Lee R, Horwitz B, Steen H, Bachur R. Discovery and validation of urine markers of acute pediatric appendicitis using high-accuracy mass spectrometry. Ann Emerg Med. Jan 2010;55(1):62-70 e64.
• Neuman MI, Monuteaux MC, Scully KJ, Bachur RG. Prediction of pneumonia in a pediatric emergency department. Pediatrics. Aug 2011;128(2):246-253.
Bachur RG, Dayan PS, Bajaj L, et al. The effect of abdominal pain duration on the accuracy of diagnostic imaging for pediatric appendicitis. Ann Emerg Med. Nov 2012;60(5):582-590 e583.
Bachur RG, Callahan MJ, Monuteaux MC, Rangel S. Integration of Ultrasound Findings and A Clinical Score in the Diagnostic Evaluation of Pediatric Appendicitis. Journal of Pediatrics May 2015, 166(5):1134-9. 

Publications

Publications powered by Harvard Catalyst Profiles
  1. Michelson KA, Bachur RG, Levy JA. The impact of critically ill children on paediatric ED medication timeliness. Emerg Med J. 2016 Sep 28.
  2. Michelson KA, Stack AM, Bachur RG. Development of a Model to Measure Emergency Department Staffing Limitations. Pediatr Emerg Care. 2016 Sep; 32(9):599-602.
  3. Nelson KA, Morrow C, Wingerter SL, Bachur RG, Neuman MI. Impact of Chest Radiography on Antibiotic Treatment for Children With Suspected Pneumonia. Pediatr Emerg Care. 2016 Aug; 32(8):514-9.
  4. Shah S, Bourgeois F, Mannix R, Nelson K, Bachur R, Neuman MI. Emergency Department Management of Febrile Respiratory Illness in Children. Pediatr Emerg Care. 2016 Jul; 32(7):429-34.
  5. Muntel J, Xuan Y, Berger ST, Reiter L, Bachur R, Kentsis A, Steen H. Advancing Urinary Protein Biomarker Discovery by Data-Independent Acquisition on a Quadrupole-Orbitrap Mass Spectrometer. J Proteome Res. 2015 Nov 6; 14(11):4752-62.
  6. Lessenich EM, Kimia AA, Mandeville K, Li J, Landschaft A, Tsai A, Bachur RG. The Frequency of Postreduction Interventions After Successful Enema Reduction of Intussusception. Acad Emerg Med. 2015 Sep; 22(9):1042-7.
  7. Melendez E, Bachur R. Quality improvement in pediatric sepsis. Curr Opin Pediatr. 2015 Jun; 27(3):298-302.
  8. Kimia AA, Bachur RG, Torres A, Harper MB. Febrile seizures: emergency medicine perspective. Curr Opin Pediatr. 2015 Jun; 27(3):292-7.
  9. Bachur RG, Monuteaux MC, Neuman MI. A comparison of acute treatment regimens for migraine in the emergency department. Pediatrics. 2015 Feb; 135(2):232-8.
  10. Meehan WP, Bachur RG. The recommendation for rest following acute concussion. Pediatrics. 2015 Feb; 135(2):362-3.
  11. Show all
  12. Meehan WP, Mannix R, Monuteaux MC, Stein CJ, Bachur RG. Early symptom burden predicts recovery after sport-related concussion. Neurology. 2014 Dec 9; 83(24):2204-10.
  13. Bachur RG, Adams CM, Monuteaux MC. Evaluating the child with acute hip pain ("irritable hip") in a Lyme endemic region. J Pediatr. 2015 Feb; 166(2):407-11.e1.
  14. Levas MN, Dayan PS, Mittal MK, Stevenson MD, Bachur RG, Dudley NC, Bajaj L, Macias CG, Bennett J, Dowd MD, Thomas AJ, Kharbanda AB. Effect of Hispanic ethnicity and language barriers on appendiceal perforation rates and imaging in children. J Pediatr. 2014 Jun; 164(6):1286-91.e2.
  15. Vieira RL, Bachur R. Bedside ultrasound in pediatric practice. Pediatrics. 2014 Jan; 133(1):1-3.
  16. Levy JA, Waltzman M, Monuteaux MC, Bachur RG. Value of point-of-care ketones in assessing dehydration and acidosis in children with gastroenteritis. Acad Emerg Med. 2013 Nov; 20(11):1146-50.
  17. Niescierenko M, Bachur R. Advances in pediatric dehydration therapy. Curr Opin Pediatr. 2013 Jun; 25(3):304-9.
  18. Sahyoun C, Fleegler E, Kleinman M, Monuteaux MC, Bachur R. Early identification of children at risk for critical care: standardizing communication for inter-emergency department transfers. Pediatr Emerg Care. 2013 Apr; 29(4):419-24.
  19. Nagler J, Pina C, Weiner DL, Nagler A, Monuteaux MC, Bachur RG. Use of an automated case log to improve trainee evaluations on a pediatric emergency medicine rotation. Pediatr Emerg Care. 2013 Mar; 29(3):314-8.
  20. Kentsis A, Shulman A, Ahmed S, Brennan E, Monuteaux MC, Lee YH, Lipsett S, Paulo JA, Dedeoglu F, Fuhlbrigge R, Bachur R, Bradwin G, Arditi M, Sundel RP, Newburger JW, Steen H, Kim S. Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease. EMBO Mol Med. 2013 Feb; 5(2):210-20.
  21. Levy JA, Bachur RG, Monuteaux MC, Waltzman M. Intravenous dextrose for children with gastroenteritis and dehydration: a double-blind randomized controlled trial. Ann Emerg Med. 2013 Mar; 61(3):281-8.
  22. Kharbanda AB, Dudley NC, Bajaj L, Stevenson MD, Macias CG, Mittal MK, Bachur RG, Bennett JE, Sinclair K, Huang C, Dayan PS. Validation and refinement of a prediction rule to identify children at low risk for acute appendicitis. Arch Pediatr Adolesc Med. 2012 Aug; 166(8):738-44.
  23. Dull KE, Bachur RG. Simulation in the pediatric emergency department. Clin Pediatr (Phila). 2012 Aug; 51(8):711-7.
  24. Easter JS, Bachur R. Physicians' assessment of pediatric returns to the Emergency Department. J Emerg Med. 2013 Mar; 44(3):682-8.
  25. Michelson KA, Monuteaux MC, Stack AM, Bachur RG. Pediatric emergency department crowding is associated with a lower likelihood of hospital admission. Acad Emerg Med. 2012 Jul; 19(7):816-20.
  26. Li J, Monuteaux MC, Bachur RG. Interfacility transfers of noncritically ill children to academic pediatric emergency departments. Pediatrics. 2012 Jul; 130(1):83-92.
  27. Bachur RG, Hennelly K, Callahan MJ, Chen C, Monuteaux MC. Diagnostic imaging and negative appendectomy rates in children: effects of age and gender. Pediatrics. 2012 May; 129(5):877-84.
  28. Flores G, Abreu M, Barone CP, Bachur R, Lin H. Errors of medical interpretation and their potential clinical consequences: a comparison of professional versus ad hoc versus no interpreters. Ann Emerg Med. 2012 Nov; 60(5):545-53.
  29. Kharbanda AB, Stevenson MD, Macias CG, Sinclair K, Dudley NC, Bennett J, Bajaj L, Mittal MK, Huang C, Bachur RG, Dayan PS. Interrater reliability of clinical findings in children with possible appendicitis. Pediatrics. 2012 Apr; 129(4):695-700.
  30. Kentsis A, Ahmed S, Kurek K, Brennan E, Bradwin G, Steen H, Bachur R. Detection and diagnostic value of urine leucine-rich a-2-glycoprotein in children with suspected acute appendicitis. Ann Emerg Med. 2012 Jul; 60(1):78-83.e1.
  31. Weihmiller SN, Monuteaux MC, Bachur RG. Ability of pediatric physicians to judge the likelihood of intussusception. Pediatr Emerg Care. 2012 Feb; 28(2):136-40.
  32. Hennelly KE, Bachur R. Appendicitis update. Curr Opin Pediatr. 2011 Jun; 23(3):281-5.
  33. Wingerter S, Bachur R. Risk factors for contamination of catheterized urine specimens in febrile children. Pediatr Emerg Care. 2011 Jan; 27(1):1-4.
  34. Meehan WP, Fleegler E, Bachur RG. Adherence to guidelines for managing the well-appearing febrile infant: assessment using a case-based, interactive survey. Pediatr Emerg Care. 2010 Dec; 26(12):875-80.
  35. Shah S, Bachur R, Kim D, Neuman MI. Lack of predictive value of tachypnea in the diagnosis of pneumonia in children. Pediatr Infect Dis J. 2010 May; 29(5):406-9.
  36. Wolff M, Bachur R. Serious bacterial infection in recently immunized young febrile infants. Acad Emerg Med. 2009 Dec; 16(12):1284-9.
  37. Allister L, Bachur R, Glickman J, Horwitz B. Serum markers in acute appendicitis. J Surg Res. 2011 Jun 1; 168(1):70-5.
  38. Kentsis A, Lin YY, Kurek K, Calicchio M, Wang YY, Monigatti F, Campagne F, Lee R, Horwitz B, Steen H, Bachur R. Discovery and validation of urine markers of acute pediatric appendicitis using high-accuracy mass spectrometry. Ann Emerg Med. 2010 Jan; 55(1):62-70.e4.
  39. Nagler J, Bachur RG. Advanced airway management. Curr Opin Pediatr. 2009 Jun; 21(3):299-305.
  40. Thompson A, Mannix R, Bachur R. Acute pediatric monoarticular arthritis: distinguishing lyme arthritis from other etiologies. Pediatrics. 2009 Mar; 123(3):959-65.
  41. Meehan WP, Bachur RG. Sport-related concussion. Pediatrics. 2009 Jan; 123(1):114-23.
  42. Madati PJ, Bachur R. Development of an emergency department triage tool to predict acidosis among children with gastroenteritis. Pediatr Emerg Care. 2008 Dec; 24(12):822-30.
  43. Levy JA, Bachur RG. Bedside ultrasound in the pediatric emergency department. Curr Opin Pediatr. 2008 Jun; 20(3):235-42.
  44. Meehan WP, Bachur RG. Predictors of cerebrospinal fluid pleocytosis in febrile infants aged 0 to 90 days. Pediatr Emerg Care. 2008 May; 24(5):287-93.
  45. Bachur RG, Nagler J. Use of an automated electronic case log to assess fellowship training: tracking the pediatric emergency medicine experience. Pediatr Emerg Care. 2008 Feb; 24(2):75-82.
  46. Kharbanda AB, Fishman SJ, Bachur RG. Comparison of pediatric emergency physicians' and surgeons' evaluation and diagnosis of appendicitis. Acad Emerg Med. 2008 Feb; 15(2):119-25.
  47. Colvin JM, Bachur R, Kharbanda A. The presentation of appendicitis in preadolescent children. Pediatr Emerg Care. 2007 Dec; 23(12):849-55.
  48. Bachur R, Nagler J. Scholarship oversight under the new American Board of Pediatrics guidelines for subspecialty training: lessons learned from the first cycle. Pediatr Emerg Care. 2007 Nov; 23(11):771-3.
  49. Mannix R, Bachur R. Status asthmaticus in children. Curr Opin Pediatr. 2007 Jun; 19(3):281-7.
  50. Hoppa E, Bachur R. Lyme disease update. Curr Opin Pediatr. 2007 Jun; 19(3):275-80.
  51. Schneider C, Kharbanda A, Bachur R. Evaluating appendicitis scoring systems using a prospective pediatric cohort. Ann Emerg Med. 2007 Jun; 49(6):778-84, 784.e1.
  52. Levy JA, Bachur RG. Intravenous dextrose during outpatient rehydration in pediatric gastroenteritis. Acad Emerg Med. 2007 Apr; 14(4):324-30.
  53. Murphy CG, van de Pol AC, Harper MB, Bachur RG. Clinical predictors of occult pneumonia in the febrile child. Acad Emerg Med. 2007 Mar; 14(3):243-9.
  54. Becker T, Kharbanda A, Bachur R. Atypical clinical features of pediatric appendicitis. Acad Emerg Med. 2007 Feb; 14(2):124-9.
  55. Byer RL, Bachur RG. Clinical deterioration among patients with fever and erythroderma. Pediatrics. 2006 Dec; 118(6):2450-60.
  56. Melendez E, Bachur R. Advances in the emergency management of pediatric sepsis. Curr Opin Pediatr. 2006 Jun; 18(3):245-53.
  57. Nagler J, Harper MB, Bachur RG. An automated electronic case log: using electronic information systems to assess training in emergency medicine. Acad Emerg Med. 2006 Jul; 13(7):733-9.
  58. Stanley R, Pagon Z, Bachur R. Hyperpyrexia among infants younger than 3 months. Pediatr Emerg Care. 2005 May; 21(5):291-4.
  59. Bachur RG, Harper MB. Predictive model for serious bacterial infections among infants younger than 3 months of age. Pediatrics. 2001 Aug; 108(2):311-6.
  60. Bachur R, Harper MB. Reliability of the urinalysis for predicting urinary tract infections in young febrile children. Arch Pediatr Adolesc Med. 2001 Jan; 155(1):60-5.
  61. Bachur R. Nonresponders: prolonged fever among infants with urinary tract infections. Pediatrics. 2000 May; 105(5):E59.
  62. Bachur R, Harper MB. Reevaluation of outpatients with Streptococcus pneumoniae bacteremia. Pediatrics. 2000 Mar; 105(3 Pt 1):502-9.
  63. Chumpa A, Bachur RG, Harper MB. Bacteremia-associated pneumococcal pneumonia and the benefit of initial parenteral antimicrobial therapy. Pediatr Infect Dis J. 1999 Dec; 18(12):1081-5.
  64. Zaidi E, Bachur R, Harper M. Non-typhi Salmonella bacteremia in children. Pediatr Infect Dis J. 1999 Dec; 18(12):1073-7.
  65. Silverstein M, Bachur R, Harper MB. Clinical implications of penicillin and ceftriaxone resistance among children with pneumococcal bacteremia. Pediatr Infect Dis J. 1999 Jan; 18(1):35-41.
  66. Rothrock SG, Green SM, Harper MB, Clark MC, McIlmail DP, Bachur R. Parenteral vs oral antibiotics in the prevention of serious bacterial infections in children with Streptococcus pneumoniae occult bacteremia: a meta-analysis. Acad Emerg Med. 1998 Jun; 5(6):599-606.
  67. Mondolfi AA, Grenier BM, Thompson JE, Bachur RG. Comparison of self-inflating bags with anesthesia bags for bag-mask ventilation in the pediatric emergency department. Pediatr Emerg Care. 1997 Oct; 13(5):312-6.
  68. Rothrock SG, Harper MB, Green SM, Clark MC, Bachur R, McIlmail DP, Giordano PA, Falk JL. Do oral antibiotics prevent meningitis and serious bacterial infections in children with Streptococcus pneumoniae occult bacteremia? A meta-analysis. Pediatrics. 1997 Mar; 99(3):438-44.
  69. Johnson CE, Bachur R, Priebe C, Barnes-Ruth A, Lovejoy FH, Hafler JP. Developing residents as teachers: process and content. Pediatrics. 1996 Jun; 97(6 Pt 1):907-16.
  70. Mao C, Harper M, McIntosh K, Reddington C, Cohen J, Bachur R, Caldwell B, Hsu HW. Invasive pneumococcal infections in human immunodeficiency virus-infected children. J Infect Dis. 1996 Apr; 173(4):870-6.
  71. Bachur R, Caputo GL. Bacteremia and meningitis among infants with urinary tract infections. Pediatr Emerg Care. 1995 Oct; 11(5):280-4.
  72. Harper MB, Bachur R, Fleisher GR. Effect of antibiotic therapy on the outcome of outpatients with unsuspected bacteremia. Pediatr Infect Dis J. 1995 Sep; 14(9):760-7.
  73. Bachur R, Pagon Z. Success of short-course parenteral antibiotic therapy for acute osteomyelitis of childhood. Clin Pediatr (Phila). 2007 Jan; 46(1):30-5.
  74. Weihmiller SN, Buonomo C, Bachur R. Risk stratification of children being evaluated for intussusception. Pediatrics. 2011 Feb; 127(2):e296-303.
  75. Neuman MI, Graham D, Bachur R. Variation in the use of chest radiography for pneumonia in pediatric emergency departments. Pediatr Emerg Care. 2011 Jul; 27(7):606-10.
  76. Bachur RG, Hennelly K, Callahan MJ, Monuteaux MC. Advanced radiologic imaging for pediatric appendicitis, 2005-2009: trends and outcomes. J Pediatr. 2012 Jun; 160(6):1034-8.
  77. Dauber A, Weiss S, Maniaci V, Nylen E, Becker KL, Bachur R. Procalcitonin levels in febrile infants after recent immunization. Pediatrics. 2008 Nov; 122(5):e1119-22.
  78. Neuman MI, Scully KJ, Kim D, Shah S, Bachur RG. Physician assessment of the likelihood of pneumonia in a pediatric emergency department. Pediatr Emerg Care. 2010 Nov; 26(11):817-22.
  79. Shah S, Mathews B, Neuman MI, Bachur R. Detection of occult pneumonia in a pediatric emergency department. Pediatr Emerg Care. 2010 Sep; 26(9):615-21.
  80. Maniaci V, Dauber A, Weiss S, Nylen E, Becker KL, Bachur R. Procalcitonin in young febrile infants for the detection of serious bacterial infections. Pediatrics. 2008 Oct; 122(4):701-10.
  81. Mannix R, Meehan WP, Monuteaux MC, Bachur RG. Computed tomography for minor head injury: variation and trends in major United States pediatric emergency departments. J Pediatr. 2012 Jan; 160(1):136-9.e1.
  82. Neuman MI, Monuteaux MC, Scully KJ, Bachur RG. Prediction of pneumonia in a pediatric emergency department. Pediatrics. 2011 Aug; 128(2):246-53.
  83. Mathews B, Shah S, Cleveland RH, Lee EY, Bachur RG, Neuman MI. Clinical predictors of pneumonia among children with wheezing. Pediatrics. 2009 Jul; 124(1):e29-36.
  84. Abo A, Shannon M, Taylor G, Bachur R. The influence of body mass index on the accuracy of ultrasound and computed tomography in diagnosing appendicitis in children. Pediatr Emerg Care. 2011 Aug; 27(8):731-6.
  85. Kharbanda AB, Taylor GA, Fishman SJ, Bachur RG. A clinical decision rule to identify children at low risk for appendicitis. Pediatrics. 2005 Sep; 116(3):709-16.
  86. Nagler J, Levy JA, Bachur RG. Stridor in an infant with myelomeningocele. Pediatr Emerg Care. 2007 Jul; 23(7):478-81.
  87. Rutman MS, Bachur R, Harper MB. Radiographic pneumonia in young, highly febrile children with leukocytosis before and after universal conjugate pneumococcal vaccination. Pediatr Emerg Care. 2009 Jan; 25(1):1-7.
  88. Bachur RG, Dayan PS, Bajaj L, Macias CG, Mittal MK, Stevenson MD, Dudley NC, Sinclair K, Bennett J, Monuteaux MC, Kharbanda AB. The effect of abdominal pain duration on the accuracy of diagnostic imaging for pediatric appendicitis. Ann Emerg Med. 2012 Nov; 60(5):582-590.e3.
  89. Bachur R, Perry H, Harper MB. Occult pneumonias: empiric chest radiographs in febrile children with leukocytosis. Ann Emerg Med. 1999 Feb; 33(2):166-73.
  90. Melendez E, Bachur R. Serious adverse events during procedural sedation with ketamine. Pediatr Emerg Care. 2009 May; 25(5):325-8.
  91. Wingerter SL, Bachur RG, Monuteaux MC, Neuman MI. Application of the world health organization criteria to predict radiographic pneumonia in a US-based pediatric emergency department. Pediatr Infect Dis J. 2012 Jun; 31(6):561-4.
  92. Kharbanda AB, Taylor GA, Bachur RG. Suspected appendicitis in children: rectal and intravenous contrast-enhanced versus intravenous contrast-enhanced CT. Radiology. 2007 May; 243(2):520-6.
  93. Mittal MK, Dayan PS, Macias CG, Bachur RG, Bennett J, Dudley NC, Bajaj L, Sinclair K, Stevenson MD, Kharbanda AB. Performance of ultrasound in the diagnosis of appendicitis in children in a multicenter cohort. Acad Emerg Med. 2013 Jul; 20(7):697-702.
  94. Callahan MJ, Anandalwar SP, MacDougall RD, Stamoulis C, Kleinman PL, Rangel SJ, Bachur RG, Taylor GA. Pediatric CT dose reduction for suspected appendicitis: a practice quality improvement project using artificial gaussian noise--part 2, clinical outcomes. AJR Am J Roentgenol. 2015 Mar; 204(3):636-44.
  95. Anandalwar SP, Callahan MJ, Bachur RG, Feng C, Sidhwa F, Karki M, Taylor GA, Rangel SJ. Use of White Blood Cell Count and Polymorphonuclear Leukocyte Differential to Improve the Predictive Value of Ultrasound for Suspected Appendicitis in Children. J Am Coll Surg. 2015 Jun; 220(6):1010-7.
  96. Bachur RG, Callahan MJ, Monuteaux MC, Rangel SJ. Integration of ultrasound findings and a clinical score in the diagnostic evaluation of pediatric appendicitis. J Pediatr. 2015 May; 166(5):1134-9.
  97. Nigrovic LE, Stack AM, Mannix RC, Lyons TW, Samnaliev M, Bachur RG, Proctor MR. Quality Improvement Effort to Reduce Cranial CTs for Children With Minor Blunt Head Trauma. Pediatrics. 2015 Jul; 136(1):e227-33.
  98. Bachur RG, Levy JA, Callahan MJ, Rangel SJ, Monuteaux MC. Effect of Reduction in the Use of Computed Tomography on Clinical Outcomes of Appendicitis. JAMA Pediatr. 2015 Aug; 169(8):755-60.
  99. Berger ST, Ahmed S, Muntel J, Cuevas Polo N, Bachur R, Kentsis A, Steen J, Steen H. MStern Blotting-High Throughput Polyvinylidene Fluoride (PVDF) Membrane-Based Proteomic Sample Preparation for 96-Well Plates. Mol Cell Proteomics. 2015 Oct; 14(10):2814-23.
  100. Kentsis A, Monigatti F, Dorff K, Campagne F, Bachur R, Steen H. Urine proteomics for profiling of human disease using high accuracy mass spectrometry. Proteomics Clin Appl. 2009 Sep 1; 3(9):1052-1061.
  101. Bachur RG, Dayan PS, Dudley NC, Bajaj L, Stevenson MD, Macias CG, Mittal MK, Bennett J, Sinclair K, Monuteaux MC, Kharbanda AB. The Influence of Age on the Diagnostic Performance of White Blood Cell Count and Absolute Neutrophil Count in Suspected Pediatric Appendicitis. Acad Emerg Med. 2016 Nov; 23(11):1235-1242.
  102. Hirsch AW, Monuteaux MC, Fruchtman G, Bachur RG, Neuman MI. Characteristics of Children Hospitalized With Aspiration Pneumonia. Hosp Pediatr. 2016 Nov; 6(11):659-666.
LIke ThisLIke ThisLIke This
Close