Recipient of NIH Mentored Clinical Scientist Development Award (K08): 2013-2018
Project Title: Immediate and Delayed Effects of Morphine on Brain Circuits: Animal - Human Correlation
Opioids are considered standard of care and used for management of acute pain, as well as for sedation of children of all ages. Our understanding of sequelae associated with prolonged opioid treatment on developing brain are limited. The is unique aspect of this project is in its translational effort to define the impact of prolonged morphine exposure in the rats of different ages using neuroimaging, behavioral, and immunohistochemical techniques (AIM 1), as well as in children of different ages using neuroimaging (AIM 2). Functional magnetic resonance imaging (fMRI) in both rats and children will allow a translational systems level investigation of prolonged morphine administration and its long-term effects.
About Dusica Bajic
Dr. Bajic received her MD from the Medical School of the University of Belgrade, Serbia and PhD from the Department of Pharmacology at the University of Illinois at Chicago, IL. Her postdoctoral training included: (1) Postdoctoral Fellow at the Department of Anatomy and Cell Biology at the University of Illinois at Chicago, (2) Anesthesia Residency training at Yale New Haven Hospital, Yale University, as well as (3) Pediatric Anesthesia Fellowship at Children's Hospital Boston, Harvard University where she now works as board certified staff anesthesiologist since 2008.