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David  Briscoe, MB, ChB

Research Center:
Transplant Research Program
Nephrology Research
Hospital Title:
Director, Transplant Research Program and Fellowship Program
Academic Title:
Associate Professor of Medicine, Harvard Medical School
Research Focus Area:
Transplant rejection
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About David Briscoe

Dr. David Briscoe is an Associate Professor of Pediatrics at Harvard Medical School and the Casey Lee Ball Chair in Transplantation at Boston Children's Hospital. He trained in Pediatrics, Nephrology and transplantation immunology, and directs a research program focused on the understanding of chronic allograft rejection with a goal to enhance long-term outcomes following solid organ transplantation.

Dr. Briscoe earned his medical degree at the Royal College of Surgeons in Ireland and performed his initial residency training in General Medicine and Pediatrics in Dublin. He also completed Pediatric Residency training at the University of Colorado Health Sciences Center in Denver, Colorado, and a postdoctoral fellowship in Pediatric Nephrology at Boston Children’s Hospital and Harvard Medical School. Among several honors, Dr. Briscoe was awarded a Young Investigator Award and the Basic Science Investigator Award of the American Society of Transplantation. He was also elected to the national honors society, the American Society of Clinical Investigation in 2004. In 2008, Dr. Briscoe became the Fellowship Program Director in Pediatric Nephrology at Boston Children's Hospital and Principal Investigator of a T32 training program grant. In 2013, he was appointed Director of the Transplant Research Program at Boston Children’s Hospital, and in 2015, he became the first incumbent Casey Lee Ball Chair in Transplantation.

Dr. Briscoe belongs to a number of Professional Societies, including the Pediatric Academic Societies, the American Society of Transplantation, the American Society of Transplant Surgeons and the American Society of Nephrology. He has held leadership positions, both national and international, including being a member of the Board of Directors of the American Society of Transplantation, the Executive Committee Chair for the American Transplant Congress, Program Chair in Immunology for the Annual Meeting of the American Society of Nephrology and Chair of the Public Policy Committee for the American Society of Transplantation. Currently, Dr. Briscoe serves as a Councilor for the International Pediatric Transplant Association, an affiliate of the Transplantation Society. In these positions, Dr. Briscoe has been a strong advocate for pediatric transplant recipients, and he is most supportive of discovery-based research, translational research and clinical trials in the field to impact long-term care. He is also a strong advocate for the training of physicians and scientists in biomedical research.

Dr. Briscoe’s research focuses on endothelial immunobiology and immune-mediated angiogenesis as underlying mechanisms in chronic allograft rejection. He has held several NIH R01 grants, a program project grant, and he has been involved in multicenter clinical trials to advance biomarker development and translational research initiatives.  He also serves as a standing member on a NIH study section and is a regular reviewer on special grant review committees to provide transplant expertise. He has also served on the editorial board of several transplant journals and is currently the senior editor of Transplantation Direct.

For more about Dr. Briscoe’s research, please visit

Key Publications

View Dr.Briscoe’s publications in PubMed.

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