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Charles  Berde, MD, PhD

Charles Berde
Department of Anesthesiology, Perioperative and Pain Medicine Research
Pain Medicine Research
Hospital Title:
Chief, Division of Pain Medicine
Academic Title:
Professor of Pediatrics, Harvard Medical School
Research Focus Area:
Pain management
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Research Overview

Charles Berde's research focuses on relieving neuropathic pain in children. The Pain Treatment Service at Children's Hospital in Boston has become a referral center for children with many types of neuropathic pain, but especially limb pain associated with signs of abnormal circulation, which has been variously named reflex sympathetic (or neurovascular) dystrophy (RSD/RND), sympathetically maintained pain (SMP), and complex regional pain syndrome type 1 (CRPS1). 

About Charles Berde

Charles Berde received an MD and PhD from Stanford University School of Medicine. He completed an internship and residency in pediatrics at Children's Hospital Boston, a residency in anesthesia at Massachusetts General Hospital, and a fellowship in pediatric anesthesia at Children's Hospital. He has received several awards and honors for his pioneering work in pediatric pain relief, including the 2003 Scientific Achievement Award of the Reflex Sympathetic Dystrophy Syndrome Association. He was profiled as one of Time Magazine's "Heroes in Medicine" in 1997.


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  1. Simons LE, Sieberg CB, Conroy C, Randall ET, Shulman J, Borsook D, Berde C, Sethna NF, Logan DE. Children With Chronic Pain: Response Trajectories After Intensive Pain Rehabilitation Treatment. J Pain. 2018 Feb; 19(2):207-218.
  2. Walco GA, Kopecky EA, Weisman SJ, Stinson J, Stevens B, Desjardins PJ, Berde CB, Krane EJ, Anand KJ, Yaster M, Dampier CD, Dworkin RH, Gilron I, Lynn AM, Maxwell LG, Raja S, Schachtel B, Turk DC. Clinical trial designs and models for analgesic medications for acute pain in neonates, infants, toddlers, children, and adolescents: ACTTION recommendations. Pain. 2017 Nov 13.
  3. Cornelissen L, Donado C, Lee JM, Liang NE, Mills I, Tou A, Bilge A, Berde CB. Clinical signs and electroencephalographic patterns of emergence from sevoflurane anaesthesia in children: An observational study. Eur J Anaesthesiol. 2017 Nov 08.
  4. Donado C, Lobo K, Velarde-Álvarez MF, Kim J, Kenney A, Logan D, Berde CB. Continuous Regional Anesthesia and Inpatient Rehabilitation for Pediatric Complex Regional Pain Syndrome. Reg Anesth Pain Med. 2017 Jul/Aug; 42(4):527-534.
  5. Cornelissen L, Bergin AM, Lobo K, Donado C, Soul JS, Berde CB. Electroencephalographic discontinuity during sevoflurane anesthesia in infants and children. Paediatr Anaesth. 2017 Mar; 27(3):251-262.
  6. Robinson S, Robertson FC, Dasenbrock HH, O'Brien CP, Berde C, Padua H. Image-guided intrathecal baclofen pump catheter implantation: a technical note and case series. J Neurosurg Spine. 2017 May; 26(5):621-627.
  7. Peake RW, Zhang VY, Azcue N, Hartigan CE, Shkreta A, Prabhakara J, Berde CB, Kellogg MD. Measurement of neosaxitoxin in human plasma using liquid-chromatography tandem mass spectrometry: Proof of concept for a pharmacokinetic application. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Nov 15; 1036-1037:42-49.
  8. Cornelissen L, Berde C. Biomedical science: Protection for anaesthetized mice. Nature. 2016 08 04; 536(7614):36-7.
  9. Berde C, Koka A, Donado-Rincon C. Lidocaine Infusions and Other Options for Opioid-Resistant Pain Due to Pediatric Advanced Cancer. Pediatr Blood Cancer. 2016 07; 63(7):1141-3.
  10. Chalkiadis GA, Berde C. Bundled analgesia interventions for day-stay surgery. Paediatr Anaesth. 2016 Feb; 26(2):120-1.
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  12. Simons LE, Erpelding N, Hernandez JM, Serrano P, Zhang K, Lebel AA, Sethna NF, Berde CB, Prabhu SP, Becerra L, Borsook D. Fear and Reward Circuit Alterations in Pediatric CRPS. Front Hum Neurosci. 2015; 9:703.
  13. Kurgansky KE, Rodriguez ST, Kralj MS, Mooney JJ, Dinakar P, d'Hemecourt PA, Hedequist DJ, Proctor MR, Berde CB. Epidural Steroid Injections for Radiculopathy and/or Back Pain in Children and Adolescents: A Retrospective Cohort Study With a Prospective Follow-Up. Reg Anesth Pain Med. 2016 Jan-Feb; 41(1):86-92.
  14. Davidson AJ, Disma N, de Graaff JC, Withington DE, Dorris L, Bell G, Stargatt R, Bellinger DC, Schuster T, Arnup SJ, Hardy P, Hunt RW, Takagi MJ, Giribaldi G, Hartmann PL, Salvo I, Morton NS, von Ungern Sternberg BS, Locatelli BG, Wilton N, Lynn A, Thomas JJ, Polaner D, Bagshaw O, Szmuk P, Absalom AR, Frawley G, Berde C, Ormond GD, Marmor J, McCann ME. Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial. Lancet. 2016 Jan 16; 387(10015):239-50.
  15. Poorun R, Hartley C, Goksan S, Worley A, Boyd S, Cornelissen L, Berde C, Rogers R, Ali T, Slater R. Electroencephalography during general anaesthesia differs between term-born and premature-born children. Clin Neurophysiol. 2016 Feb; 127(2):1216-1222.
  16. Lobo K, Donado C, Cornelissen L, Kim J, Ortiz R, Peake RW, Kellogg M, Alexander ME, Zurakowski D, Kurgansky KE, Peyton J, Bilge A, Boretsky K, McCann ME, Berde CB, Cravero J. A Phase 1, Dose-escalation, Double-blind, Block-randomized, Controlled Trial of Safety and Efficacy of Neosaxitoxin Alone and in Combination with 0.2% Bupivacaine, with and without Epinephrine, for Cutaneous Anesthesia. Anesthesiology. 2015 Oct; 123(4):873-85.
  17. Templin JS, Wylie MC, Kim JD, Kurgansky KE, Gorski G, Kheir J, Zurakowski D, Corfas G, Berde C. Neosaxitoxin in Rat Sciatic Block: Improved Therapeutic Index Using Combinations with Bupivacaine, with and without Epinephrine. Anesthesiology. 2015 Oct; 123(4):886-98.
  18. Cornelissen L, Kim SE, Purdon PL, Brown EN, Berde CB. Age-dependent electroencephalogram (EEG) patterns during sevoflurane general anesthesia in infants. Elife. 2015 Jun 23; 4:e06513.
  19. Garibyan L, Cornelissen L, Sipprell W, Pruessner J, Elmariah S, Luo T, Lerner EA, Jung Y, Evans C, Zurakowski D, Berde CB, Rox Anderson R. Transient Alterations of Cutaneous Sensory Nerve Function by Noninvasive Cryolipolysis. J Invest Dermatol. 2015 Nov; 135(11):2623-2631.
  20. Berde C. Developing better local anesthetics. Anesth Analg. 2015 Apr; 120(4):718-20.
  21. Bajic D, Soiza-Reilly M, Spalding AL, Berde CB, Commons KG. Endogenous cholinergic neurotransmission contributes to behavioral sensitization to morphine. PLoS One. 2015; 10(2):e0117601.
  22. Kossowsky J, Donado C, Berde CB. Immediate rescue designs in pediatric analgesic trials: a systematic review and meta-analysis. Anesthesiology. 2015 Jan; 122(1):150-171.
  23. Cornelissen L, Donado C, Kim J, Chiel L, Zurakowski D, Logan DE, Meier P, Sethna NF, Blankenburg M, Zernikow B, Sundel RP, Berde CB. Pain hypersensitivity in juvenile idiopathic arthritis: a quantitative sensory testing study. Pediatr Rheumatol Online J. 2014; 12:39.
  24. Becerra L, Sava S, Simons LE, Drosos AM, Sethna N, Berde C, Lebel AA, Borsook D. Intrinsic brain networks normalize with treatment in pediatric complex regional pain syndrome. Neuroimage Clin. 2014; 6:347-69.
  25. Simons LE, Pielech M, Erpelding N, Linnman C, Moulton E, Sava S, Lebel A, Serrano P, Sethna N, Berde C, Becerra L, Borsook D. The responsive amygdala: treatment-induced alterations in functional connectivity in pediatric complex regional pain syndrome. Pain. 2014 Sep; 155(9):1727-42.
  26. Berde CB, Boretsky KR, Cravero JP. Paravertebral block for analgesia after pediatric thoracic surgery. Reg Anesth Pain Med. 2014 May-Jun; 39(3):179-80.
  27. Solodiuk JC, Brighton H, McHale J, LoChiatto J, Logan DE, Sager S, Zurakowski D, Berde CB. Documented electronic medical record-based pain intensity scores at a tertiary pediatric medical center: a cohort analysis. J Pain Symptom Manage. 2014 Nov; 48(5):924-33.
  28. Jerome J, Solodiuk JC, Sethna N, McHale J, Berde C. A single institution's effort to translate codeine knowledge into specific clinical practice. J Pain Symptom Manage. 2014 Jul; 48(1):119-26.
  29. Rork JF, Berde CB, Goldstein RD. Regional anesthesia approaches to pain management in pediatric palliative care: a review of current knowledge. J Pain Symptom Manage. 2013 Dec; 46(6):859-73.
  30. Allee JI, Goins KM, Berde CB, McCann ME. A case of cerebrospinal fluid leak in an infant after spinal anesthesia. J Clin Anesth. 2013 May; 25(3):217-9.
  31. Linnman C, Becerra L, Lebel A, Berde C, Grant PE, Borsook D. Transient and persistent pain induced connectivity alterations in pediatric complex regional pain syndrome. PLoS One. 2013; 8(3):e57205.
  32. Logan DE, Williams SE, Carullo VP, Claar RL, Bruehl S, Berde CB. Children and adolescents with complex regional pain syndrome: more psychologically distressed than other children in pain? Pain Res Manag. 2013 Mar-Apr; 18(2):87-93.
  33. Berde C, Greco C. Pediatric regional anesthesia: drawing inferences on safety from prospective registries and case reports. Anesth Analg. 2012 Dec; 115(6):1259-62.
  34. Logan DE, Carpino EA, Chiang G, Condon M, Firn E, Gaughan VJ, Hogan M, Leslie DS, Olson K, Sager S, Sethna N, Simons LE, Zurakowski D, Berde CB. A day-hospital approach to treatment of pediatric complex regional pain syndrome: initial functional outcomes. Clin J Pain. 2012 Nov-Dec; 28(9):766-74.
  35. Bajic D, Berde CB, Commons KG. Periaqueductal gray neuroplasticity following chronic morphine varies with age: role of oxidative stress. Neuroscience. 2012 Dec 13; 226:165-77.
  36. Templin JS, Bang SJ, Soiza-Reilly M, Berde CB, Commons KG. Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas. Brain Res. 2012 May 31; 1457:1-12.
  37. Wylie MC, Johnson VM, Carpino E, Mullen K, Hauser K, Nedder A, Kheir JN, Rodriguez-Navarro AJ, Zurakowski D, Berde CB. Respiratory, neuromuscular, and cardiovascular effects of neosaxitoxin in isoflurane-anesthetized sheep. Reg Anesth Pain Med. 2012 Mar-Apr; 37(2):152-8.
  38. Oaklander AL, Wilson PR, Moskovitz PA, Manning DC, Lubenow T, Levine JD, Harden RN, Galer BS, Cooper MS, Bruehl S, Broatch J, Berde C, Bennett GJ. Response to "A new definition of neuropathic pain". Pain. 2012 Apr; 153(4):934-5; author reply 935-6.
  39. Berde CB, Walco GA, Krane EJ, Anand KJ, Aranda JV, Craig KD, Dampier CD, Finkel JC, Grabois M, Johnston C, Lantos J, Lebel A, Maxwell LG, McGrath P, Oberlander TF, Schanberg LE, Stevens B, Taddio A, von Baeyer CL, Yaster M, Zempsky WT. Pediatric analgesic clinical trial designs, measures, and extrapolation: report of an FDA scientific workshop. Pediatrics. 2012 Feb; 129(2):354-64.
  40. Sethna NF, Berde CB. Sympathetic nerve blocks, pragmatic trials, and responder analysis. Anesthesiology. 2012 Jan; 116(1):12-4.
  41. Berde CB, Athiraman U, Yahalom B, Zurakowski D, Corfas G, Bognet C. Tetrodotoxin-bupivacaine-epinephrine combinations for prolonged local anesthesia. Mar Drugs. 2011 Dec; 9(12):2717-28.
  42. Yahalom B, Athiraman U, Soriano SG, Zurakowski D, Carpino EA, Corfas G, Berde CB. Spinal anesthesia in infant rats: development of a model and assessment of neurologic outcomes. Anesthesiology. 2011 Jun; 114(6):1325-35.
  43. Rodríguez-Navarro AJ, Berde CB, Wiedmaier G, Mercado A, Garcia C, Iglesias V, Zurakowski D. Comparison of neosaxitoxin versus bupivacaine via port infiltration for postoperative analgesia following laparoscopic cholecystectomy: a randomized, double-blind trial. Reg Anesth Pain Med. 2011 Mar-Apr; 36(2):103-9.
  44. Simons LE, Sieberg CB, Carpino E, Logan D, Berde C. The Fear of Pain Questionnaire (FOPQ): assessment of pain-related fear among children and adolescents with chronic pain. J Pain. 2011 Jun; 12(6):677-86.
  45. Ullrich CK, Dussel V, Hilden JM, Sheaffer JW, Moore CL, Berde CB, Wolfe J. Fatigue in children with cancer at the end of life. J Pain Symptom Manage. 2010 Oct; 40(4):483-94.
  46. Berde CB, Stevens B. Blood sampling and other needle procedures - the Achilles heel of newborn intensive care. Pain. 2009 Dec 15; 147(1-3):15-6.
  47. Berde C, McGrath P. Pain measurement and Beecher's challenge: 50 years later. Anesthesiology. 2009 Sep; 111(3):473-4.
  48. Meier PM, Zurakowski D, Berde CB, Sethna NF. Lumbar sympathetic blockade in children with complex regional pain syndromes: a double blind placebo-controlled crossover trial. Anesthesiology. 2009 Aug; 111(2):372-80.
  49. Sava S, Lebel AA, Leslie DS, Drosos A, Berde C, Becerra L, Borsook D. Challenges of functional imaging research of pain in children. Mol Pain. 2009 Jun 16; 5:30.
  50. Ababneh ZQ, Beloeil H, Berde CB, Ababneh AM, Maier SE, Mulkern RV. In vivo lipid diffusion coefficient measurements in rat bone marrow. Magn Reson Imaging. 2009 Jul; 27(6):859-64.
  51. Lebel A, Becerra L, Wallin D, Moulton EA, Morris S, Pendse G, Jasciewicz J, Stein M, Aiello-Lammens M, Grant E, Berde C, Borsook D. fMRI reveals distinct CNS processing during symptomatic and recovered complex regional pain syndrome in children. Brain. 2008 Jul; 131(Pt 7):1854-79.
  52. Berde C, Nurko S. Opioid side effects--mechanism-based therapy. N Engl J Med. 2008 May 29; 358(22):2400-2.
  53. Wolfe J, Hammel JF, Edwards KE, Duncan J, Comeau M, Breyer J, Aldridge SA, Grier HE, Berde C, Dussel V, Weeks JC. Easing of suffering in children with cancer at the end of life: is care changing? J Clin Oncol. 2008 Apr 01; 26(10):1717-23.
  54. Needleman HL, Harpavat S, Wu S, Allred EN, Berde C. Postoperative pain and other sequelae of dental rehabilitations performed on children under general anesthesia. Pediatr Dent. 2008 Mar-Apr; 30(2):111-21.
  55. Berde CB, Yaster M, Meretoja O, McCann ME, Huledal G, Gustafsson U, Larsson LE. Stable plasma concentrations of unbound ropivacaine during postoperative epidural infusion for 24-72 hours in children. Eur J Anaesthesiol. 2008 May; 25(5):410-7.
  56. Dimitrakov J, Kroenke K, Steers WD, Berde C, Zurakowski D, Freeman MR, Jackson JL. Pharmacologic management of painful bladder syndrome/interstitial cystitis: a systematic review. Arch Intern Med. 2007 Oct 08; 167(18):1922-9.
  57. Wen YR, Suter MR, Kawasaki Y, Huang J, Pertin M, Kohno T, Berde CB, Decosterd I, Ji RR. Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model. Anesthesiology. 2007 Aug; 107(2):312-21.
  58. Sethna NF, Meier PM, Zurakowski D, Berde CB. Cutaneous sensory abnormalities in children and adolescents with complex regional pain syndromes. Pain. 2007 Sep; 131(1-2):153-61.
  59. Beloeil H, Ababneh Z, Chung R, Zurakowski D, Mulkern RV, Berde CB. Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 1): hyperalgesia, edema, and systemic cytokines. Anesthesiology. 2006 Jul; 105(1):128-38.
  60. Beloeil H, Ji RR, Berde CB. Effects of bupivacaine and tetrodotoxin on carrageenan-induced hind paw inflammation in rats (Part 2): cytokines and p38 mitogen-activated protein kinases in dorsal root ganglia and spinal cord. Anesthesiology. 2006 Jul; 105(1):139-45.
  61. Ullrich CK, Hilden JM, Sheaffer JW, Moore CL, Berde CB, Weeks JC, Wolfe J. Factors associated with fatigue in children with cancer at the end of life. J Clin Oncol. 2006 Jun 20; 24(18_suppl):8574.
  62. Meier PM, Alexander ME, Sethna NF, De Jong-De Vos Van Steenwijk CC, Zurakowski D, Berde CB. Complex regional pain syndromes in children and adolescents: regional and systemic signs and symptoms and hemodynamic response to tilt table testing. Clin J Pain. 2006 May; 22(4):399-406.
  63. Anand KJ, Aranda JV, Berde CB, Buckman S, Capparelli EV, Carlo W, Hummel P, Johnston CC, Lantos J, Tutag-Lehr V, Lynn AM, Maxwell LG, Oberlander TF, Raju TN, Soriano SG, Taddio A, Walco GA. Summary proceedings from the neonatal pain-control group. Pediatrics. 2006 Mar; 117(3 Pt 2):S9-S22.
  64. Lin YC, Lee AC, Kemper KJ, Berde CB. Use of complementary and alternative medicine in pediatric pain management service: a survey. Pain Med. 2005 Nov-Dec; 6(6):452-8.
  65. Ababneh Z, Beloeil H, Berde CB, Gambarota G, Maier SE, Mulkern RV. Biexponential parameterization of diffusion and T2 relaxation decay curves in a rat muscle edema model: decay curve components and water compartments. Magn Reson Med. 2005 Sep; 54(3):524-31.
  66. Greco C, Berde C. Pain management for the hospitalized pediatric patient. Pediatr Clin North Am. 2005 Aug; 52(4):995-1027, vii-viii.
  67. Tsui BC, Berde CB. Caudal analgesia and anesthesia techniques in children. Curr Opin Anaesthesiol. 2005 Jun; 18(3):283-8.
  68. Anand KJ, Aranda JV, Berde CB, Buckman S, Capparelli EV, Carlo WA, Hummel P, Lantos J, Johnston CC, Lehr VT, Lynn AM, Maxwell LG, Oberlander TF, Raju TN, Soriano SG, Taddio A, Walco GA. Analgesia and anesthesia for neonates: study design and ethical issues. Clin Ther. 2005 Jun; 27(6):814-43.
  69. Berde CB, Jaksic T, Lynn AM, Maxwell LG, Soriano SG, Tibboel D. Anesthesia and analgesia during and after surgery in neonates. Clin Ther. 2005 Jun; 27(6):900-21.
  70. Sethna NF, Verghese ST, Hannallah RS, Solodiuk JC, Zurakowski D, Berde CB. A randomized controlled trial to evaluate S-Caine patch for reducing pain associated with vascular access in children. Anesthesiology. 2005 Feb; 102(2):403-8.
  71. Berde CB, Lebel A. Complex regional pain syndromes in children and adolescents. Anesthesiology. 2005 Feb; 102(2):252-5.
  72. Masuda T, Cairns BE, Sadhasivam S, Dunning PS, Berde CB. Epinephrine prevents muscle blood flow increases after perineural injection of tetrodotoxin. Anesthesiology. 2004 Dec; 101(6):1428-34.
  73. McCann ME, Waters P, Goumnerova LC, Berde C. Self-mutilation in young children following brachial plexus birth injury. Pain. 2004 Jul; 110(1-2):123-9.
  74. Berde C. Local anesthetics in infants and children: an update. Paediatr Anaesth. 2004 May; 14(5):387-93.
  75. Lin YC, Bioteau AB, Ferrari LR, Berde CB. The use of herbs and complementary and alternative medicine in pediatric preoperative patients. J Clin Anesth. 2004 Feb; 16(1):4-6.
  76. Wang C, Liu H, Wilder RT, Berde CB. Effects of repeated injection of local anesthetic on sciatic nerve blocks response. J Huazhong Univ Sci Technolog Med Sci. 2004; 24(5):497-9.
  77. Suter MR, Papaloïzos M, Berde CB, Woolf CJ, Gilliard N, Spahn DR, Decosterd I. Development of neuropathic pain in the rat spared nerve injury model is not prevented by a peripheral nerve block. Anesthesiology. 2003 Dec; 99(6):1402-8.
  78. Kohane DS, Smith SE, Louis DN, Colombo G, Ghoroghchian P, Hunfeld NG, Berde CB, Langer R. Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres. Pain. 2003 Jul; 104(1-2):415-21.
  79. Cairns BE, Svensson P, Wang K, Hupfeld S, Graven-Nielsen T, Sessle BJ, Berde CB, Arendt-Nielsen L. Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle. J Neurophysiol. 2003 Oct; 90(4):2098-105.
  80. Berde CB, Brennan TJ, Raja SN. Opioids: more to learn, improvements to be made. Anesthesiology. 2003 Jun; 98(6):1309-12.
  81. Berde C, Wolfe J. Pain, anxiety, distress, and suffering: interrelated, but not interchangeable. J Pediatr. 2003 Apr; 142(4):361-3.
  82. Cairns BE, Gambarota G, Dunning PS, Mulkern RV, Berde CB. Activation of peripheral excitatory amino acid receptors decreases the duration of local anesthesia. Anesthesiology. 2003 Feb; 98(2):521-9.
  83. Berde CB, Sethna NF. Analgesics for the treatment of pain in children. N Engl J Med. 2002 Oct 03; 347(14):1094-103.
  84. Palmer GM, Cairns BE, Berkes SL, Dunning PS, Taylor GA, Berde CB. The effects of lidocaine and adrenergic agonists on rat sciatic nerve and skeletal muscle blood flow in vivo. Anesth Analg. 2002 Oct; 95(4):1080-6, table of contents.
  85. Teitelbaum JE, Berde CB, Nurko S, Buonomo C, Perez-Atayde AR, Fox VL. Diagnosis and management of MNGIE syndrome in children: case report and review of the literature. J Pediatr Gastroenterol Nutr. 2002 Sep; 35(3):377-83.
  86. Lee BH, Scharff L, Sethna NF, McCarthy CF, Scott-Sutherland J, Shea AM, Sullivan P, Meier P, Zurakowski D, Masek BJ, Berde CB. Physical therapy and cognitive-behavioral treatment for complex regional pain syndromes. J Pediatr. 2002 Jul; 141(1):135-40.
  87. Palmer GM, Sundel R, Berde CB, Sethna NF. Prolonged sensory and motor deficit following short-term lumbar epidural analgesia in a patient with mixed connective tissue disease. J Pain Symptom Manage. 2002 Feb; 23(2):89-92.
  88. Cairns BE, Gambarota G, Svensson P, Arendt-Nielsen L, Berde CB. Glutamate-induced sensitization of rat masseter muscle fibers. Neuroscience. 2002; 109(2):389-99.
  89. McCann ME, Sethna NF, Mazoit JX, Sakamoto M, Rifai N, Hope T, Sullivan L, Auble SG, Berde CB. The pharmacokinetics of epidural ropivacaine in infants and young children. Anesth Analg. 2001 Oct; 93(4):893-7.
  90. Meier PM, Berde CB, DiCanzio J, Zurakowski D, Sethna NF. Quantitative assessment of cutaneous thermal and vibration sensation and thermal pain detection thresholds in healthy children and adolescents. Muscle Nerve. 2001 Oct; 24(10):1339-45.
  91. Gambarota G, Cairns BE, Berde CB, Mulkern RV. Osmotic effects on the T2 relaxation decay of in vivo muscle. Magn Reson Med. 2001 Sep; 46(3):592-9.
  92. Wang C, Sholas MG, Berde CB, DiCanzio J, Zurakowski D, Wilder RT. Evidence that spinal segmental nitric oxide mediates tachyphylaxis to peripheral local anesthetic nerve block. Acta Anaesthesiol Scand. 2001 Sep; 45(8):945-53.
  93. Kohane DS, Lu NT, Crosa GA, Kuang Y, Berde CB. High concentrations of adrenergic antagonists prolong sciatic nerve blockade by tetrodotoxin. Acta Anaesthesiol Scand. 2001 Aug; 45(7):899-905.
  94. Kohane DS, Lu NT, Cairns BE, Berde CB. Effects of adrenergic agonists and antagonists on tetrodotoxin-induced nerve block. Reg Anesth Pain Med. 2001 May-Jun; 26(3):239-45.
  95. Berde C, Cairns B. Developmental pharmacology across species: promise and problems. Anesth Analg. 2000 Jul; 91(1):1-5.
  96. Needleman HL, Hoang CD, Allred E, Hertzberg J, Berde C. Reports of pain by children undergoing rapid palatal expansion. Pediatr Dent. 2000 May-Jun; 22(3):221-6.
  97. Kemper KJ, Sarah R, Silver-Highfield E, Xiarhos E, Barnes L, Berde C. On pins and needles? Pediatric pain patients' experience with acupuncture. Pediatrics. 2000 Apr; 105(4 Pt 2):941-7.
  98. Kohane DS, Lu NT, Gökgöl-Kline AC, Shubina M, Kuang Y, Hall S, Strichartz GR, Berde CB. The local anesthetic properties and toxicity of saxitonin homologues for rat sciatic nerve block in vivo. Reg Anesth Pain Med. 2000 Jan-Feb; 25(1):52-9.
  99. Lee AC, Highfield ES, Berde CB, Kemper KJ. Survey of acupuncturists: practice characteristics and pediatric care. West J Med. 1999 Sep; 171(3):153-7.
  100. Shenkman Z, Holzman RS, Kim C, Ferrari LR, DiCanzio J, Highfield ES, Van Keuren K, Kaptchuk T, Kenna MA, Berde CB, Rockoff MA. Acupressure-acupuncture antiemetic prophylaxis in children undergoing tonsillectomy. Anesthesiology. 1999 May; 90(5):1311-6.
  101. Fauza DO, Berde CB, Fishman SJ. Prolonged local myometrial blockade prevents preterm labor after fetal surgery in a leporine model. J Pediatr Surg. 1999 Apr; 34(4):540-2.
  102. Kohane DS, Kuang Y, Lu NT, Langer R, Strichartz GR, Berde CB. Vanilloid receptor agonists potentiate the in vivo local anesthetic activity of percutaneously injected site 1 sodium channel blockers. Anesthesiology. 1999 Feb; 90(2):524-34.
  103. Kohane DS, Sankar WN, Shubina M, Hu D, Rifai N, Berde CB. Sciatic nerve blockade in infant, adolescent, and adult rats: a comparison of ropivacaine with bupivacaine. Anesthesiology. 1998 Nov; 89(5):1199-208; discussion 10A.
  104. Dräger C, Benziger D, Gao F, Berde CB. Prolonged intercostal nerve blockade in sheep using controlled-release of bupivacaine and dexamethasone from polymer microspheres. Anesthesiology. 1998 Oct; 89(4):969-79.
  105. Kohane DS, Yieh J, Lu NT, Langer R, Strichartz GR, Berde CB. A re-examination of tetrodotoxin for prolonged duration local anesthesia. Anesthesiology. 1998 Jul; 89(1):119-31.
  106. Robinson WM, Ravilly S, Berde C, Wohl ME. End-of-life care in cystic fibrosis. Pediatrics. 1997 Aug; 100(2 Pt 1):205-9.
  107. Hu D, Hu R, Berde CB. Neurologic evaluation of infant and adult rats before and after sciatic nerve blockade. Anesthesiology. 1997 Apr; 86(4):957-65.
  108. Charles Berde and Robert Langer. "Biodegradable polymer matrices for sustained delivery of local anesthetic agents". 1997.
  109. Charles Berde and Robert Langer. "Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid". 1997.
  110. Wilder RT, Sholas MG, Berde CB. NG-nitro-L-arginine methyl ester (L-NAME) prevents tachyphylaxis to local anesthetics in a dose-dependent manner. Anesth Analg. 1996 Dec; 83(6):1251-5.
  111. Oberlander TF, Berde CB, Saul JP. Halothane and cardiac autonomic control in infants: assessment with quantitative respiratory sinus arrhythmia. Pediatr Res. 1996 Nov; 40(5):710-7.
  112. Castillo J, Curley J, Hotz J, Uezono M, Tigner J, Chasin M, Wilder R, Langer R, Berde C. Glucocorticoids prolong rat sciatic nerve blockade in vivo from bupivacaine microspheres. Anesthesiology. 1996 Nov; 85(5):1157-66.
  113. Berde C. Regional anesthesia in children: what have we learned? Anesth Analg. 1996 Nov; 83(5):897-900.
  114. Collins JJ, Geake J, Grier HE, Houck CS, Thaler HT, Weinstein HJ, Twum-Danso NY, Berde CB. Patient-controlled analgesia for mucositis pain in children: a three-period crossover study comparing morphine and hydromorphone. J Pediatr. 1996 Nov; 129(5):722-8.
  115. Ravilly S, Robinson W, Suresh S, Wohl ME, Berde CB. Chronic pain in cystic fibrosis. Pediatrics. 1996 Oct; 98(4 Pt 1):741-7.
  116. Houck CS, Wilder RT, McDermott JS, Sethna NF, Berde CB. Safety of intravenous ketorolac therapy in children and cost savings with a unit dosing system. J Pediatr. 1996 Aug; 129(2):292-6.
  117. Yaster M, Kost-Byerly S, Berde C, Billet C. The management of opioid and benzodiazepine dependence in infants, children, and adolescents. Pediatrics. 1996 Jul; 98(1):135-40.
  118. Curley J, Castillo J, Hotz J, Uezono M, Hernandez S, Lim JO, Tigner J, Chasin M, Langer R, Berde C. Prolonged regional nerve blockade. Injectable biodegradable bupivacaine/polyester microspheres. Anesthesiology. 1996 Jun; 84(6):1401-10.
  119. Collins JJ, Grier HE, Sethna NF, Wilder RT, Berde CB. Regional anesthesia for pain associated with terminal pediatric malignancy. Pain. 1996 Apr; 65(1):63-9.
  120. Collins JJ, Berde CB, Grier HE, Nachmanoff DB, Kinney HC. Massive opioid resistance in an infant with a localized metastasis to the midbrain periaqueductal gray. Pain. 1995 Nov; 63(2):271-5.
  121. Collins JJ, Kerner J, Sentivany S, Berde CB. Intravenous amitriptyline in pediatrics. J Pain Symptom Manage. 1995 Aug; 10(6):471-5.
  122. Berde C. Pediatric oncology procedures: to sleep or perchance to dream? Pain. 1995 Jul; 62(1):1-2.
  123. Collins JJ, Grier HE, Kinney HC, Berde CB. Control of severe pain in children with terminal malignancy. J Pediatr. 1995 Apr; 126(4):653-7.
  124. Strafford MA, Wilder RT, Berde CB. The risk of infection from epidural analgesia in children: a review of 1620 cases. Anesth Analg. 1995 Feb; 80(2):234-8.
  125. Rusy LM, Houck CS, Sullivan LJ, Ohlms LA, Jones DT, McGill TJ, Berde CB. A double-blind evaluation of ketorolac tromethamine versus acetaminophen in pediatric tonsillectomy: analgesia and bleeding. Anesth Analg. 1995 Feb; 80(2):226-9.
  126. Oberlander TF, Berde CB, Lam KH, Rappaport LA, Saul JP. Infants tolerate spinal anesthesia with minimal overall autonomic changes: analysis of heart rate variability in former premature infants undergoing hernia repair. Anesth Analg. 1995 Jan; 80(1):20-7.
  127. Suresh S, Ravilly S, Wohl ME, Berde CB. Anesthesia and perioperative care in cystic fibrosis. Anesth. Analg. 1995.
  128. Berde CB, Twum-Danso NAY, Wilder RT, Retik AJ. Epidural analgesia accelerates recovery following major pediatric urologic reconstructive surgery. Society for Pediatric Anesthesia/American Academy of Pediatrics. 1995.
  129. Wilder RT, Sholas M, Berde CB. L-nitroso-arginine methyl ester prevents tachyphylaxis to sciatic nerve blockade in a dose-dependent manner. Anesthesiology. 1995; 83:A808.
  130. Lee KC, Wilder RT, Smith RL, Berde CB. Thermal hyperalgesia accelerates and MK-801 prevents the development of tachyphylaxis to rat sciatic nerve blockade. Anesthesiology. 1994 Nov; 81(5):1284-93.
  131. Berde C. Epidural analgesia in children. Can J Anaesth. 1994 Jul; 41(7):555-60.
  132. Rusy LM, Houck CS, Ohlms LA, Jones DT, McGill TJ, Sullivan LJ, Berde CB. A double blind evaluation of ketorolac tromethamine versus acetaminophen in the pediatric tonsillectomy patient, effects on analgesia and bleeding. American Academy of Pediatrics, Section on Anesthesiology. 1994.
  133. Yee JD, Berde CB. Dextroamphetamine or methylphenidate as adjuvants to opioid analgesia for adolescents with cancer. J Pain Symptom Manage. 1994 Feb; 9(2):122-5.
  134. Kain ZN, O'Connor TZ, Berde CB. Management of tracheobronchial and esophageal foreign bodies in children: a survey study. J Clin Anesth. 1994 Jan-Feb; 6(1):28-32.
  135. Hu D, Hu R, Berde CB. Absolute volume predicts duration of sciatic blockade better than volume/kilogram in infant and adult rats. Anesthesiology. 1994; 81:A1375.
  136. Sang CN, Sethna NF, Sullivan L, Berde CB. Evaluation of epinephrine epidural test dose in children receiving isoflurane anesthesia. Anesthesiology. 1994; 81:A1344.
  137. Blank JW, Houck CS, McClain BC, Berde CB. Cephalad advancement of epidural catheters: radiographic correlation. Anesthesiology. 1994; 81:A1345.
  138. Olsson GL, Berde CB, Krane E, McGrath PA. Neuropathic pain in children. Abstracts of the 3rd International Pediatric Pain Symposium. 1994.
  139. Sang CN, Berde CV. The safety in pediatric regional analgesia study group: a multicenter study of safety and risk factors in pediatric regional analgesia. Anesthesiology. 1994; 81:A1386.
  140. Houck CS, McClain BC, Wilder RT, Sethna NF, Berde CB. The dose-response of epidural hydromorphone in children. Anesthesiology. 1994; 81:A1346.
  141. Sholas M, Wilder RT, Berde CB. Tachyphylaxis to sciatic blockade persists in spinalized rats. Anesthesiology. 1994; 81:A964.
  142. Hu R, Hu D, Berde CB. Epinephrine prolongs sciatic nerve block in infant but not adult rats. Anesthesiology. 1994; 81:A1356.
  143. Burrows FA, Berde CB. Optimal pain relief in infants and children. BMJ. 1993 Oct 02; 307(6908):815-6.
  144. Masters DB, Berde CB, Dutta S, Turek T, Langer R. Sustained local anesthetic release from bioerodible polymer matrices: a potential method for prolonged regional anesthesia. Pharm Res. 1993 Oct; 10(10):1527-32.
  145. Wilder RT, Berde CB, Griggs CT, Chickalingaiah R, Strichartz G. Chronic exposure to lidocaine does not alter flux through sodium channels in cultured neuronal cells. Reg Anesth. 1993 Sep-Oct; 18(5):283-9.
  146. Masters DB, Berde CB, Dutta SK, Griggs CT, Hu D, Kupsky W, Langer R. Prolonged regional nerve blockade by controlled release of local anesthetic from a biodegradable polymer matrix. Anesthesiology. 1993 Aug; 79(2):340-6.
  147. Kain ZN, Berde CB, Benjamin PK, Thompson JE. Performance of pediatric resuscitation bags assessed with an infant lung simulator. Anesth Analg. 1993 Aug; 77(2):261-4.
  148. Sethna NF, Berde CB. Venous air embolism during identification of the epidural space in children. Anesth Analg. 1993 May; 76(5):925-7.
  149. Berde CB. Toxicity of local anesthetics in infants and children. J Pediatr. 1993 May; 122(5 Pt 2):S14-20.
  150. Henderson K, Sethna NF, Berde CB. Continuous caudal anesthesia for inguinal hernia repair in former preterm infants. J Clin Anesth. 1993 Mar-Apr; 5(2):129-33.
  151. Truog RD, Berde CB. Pain, euthanasia, and anesthesiologists. Anesthesiology. 1993 Feb; 78(2):353-60.
  152. Houck CS, Berde C. Pain management in pediatrics. West J Med. 1993 Feb; 158(2):178-9.
  153. Perillo M, Sethna NF, Berde CB. Intravenous isoproterenol as a marker for epidural test-dosing in children. Anesth Analg. 1993 Jan; 76(1):178-81.
  154. Ly DQ, Berde CB, Hu D, Masters DB, Hu R. Comparison of injection and sustained release bupivicaine sciatic nerve blockade between adult and weaning rats. Anesthesiology. 1993; 79(3A):A908.
  155. Hu D, Hu R, Berde CB. Comparison of sciatic nerve blockade between infant and adult rats. Anesthesiology. 1993; 79(3A):A1137.
  156. Truog RD, Berde CB, Mitchell C, Grier HE. Barbiturates in the care of the terminally ill. N Engl J Med. 1992 Dec 03; 327(23):1678-82.
  157. Berde CB. Convulsions associated with pediatric regional anesthesia. Anesth Analg. 1992 Aug; 75(2):164-6.
  158. Wilder RT, Berde CB, Wolohan M, Vieyra MA, Masek BJ, Micheli LJ. Reflex sympathetic dystrophy in children. Clinical characteristics and follow-up of seventy patients. J Bone Joint Surg Am. 1992 Jul; 74(6):910-9.
  159. Masters DB, Griggs CT, Berde CB. High sensitivity quantification of RNA from gels and autoradiograms with affordable optical scanning. Biotechniques. 1992 Jun; 12(6):902-6, 908-11.
  160. Irazuzta JE, Berde CB, Sethna NF. Laser Doppler measurements of skin blood flow before, during, and after lumbar sympathetic blockade in children and young adults with reflex sympathetic dystrophy syndrome. J Clin Monit. 1992 Jan; 8(1):16-9.
  161. Sethna NF, Berde CB. Pediatric regional anesthesia equipment. Int Anesthesiol Clin. 1992; 30(3):163-76.
  162. Kain ZN, Berde CB, Benjamin PK, Thompson JE. Performance of pediatric resuscitation bags assessed with an infant lung simulator. Anesthesiology. 1992; 77:A509.
  163. Wilder RT, Berde CB, Troshynski TJ, Cahill CA, Sethna NF. Patient-controlled analgesia in children and adolescents: safety and outcome amoung 1,589 patients. Anesthesiology. 1992; 77:A1187.
  164. Sethna NF, Berde CB, Wilder RT, Strafford MA. The risk of infection from pediatric epidural analgesia is low. Anesthesiology. 1992; 77:A1158.
  165. Sievers TD, Yee JD, Foley ME, Blanding PJ, Berde CB. Midazolam for conscious sedation during pediatric oncology procedures: safety and recovery parameters. Pediatrics. 1991 Dec; 88(6):1172-9.
  166. Sethna NF, Berde CB. Continuous subarachnoid analgesia in two adolescents with severe scoliosis and impaired pulmonary function. Reg Anesth. 1991 Nov-Dec; 16(6):333-6.
  167. Berde CB, Beyer JE, Bournaki MC, Levin CR, Sethna NF. Comparison of morphine and methadone for prevention of postoperative pain in 3- to 7-year-old children. J Pediatr. 1991 Jul; 119(1 Pt 1):136-41.
  168. Desparmet JF, Berde CB, Schwartz DC, Lunn RJ, Hershenson MB. Efficacy of adrenaline, lignocaine-adrenaline and isoprenaline as a test dose in halothane-anaesthetized lambs. Eur J Anaesthesiol. 1991 Mar; 8(2):123-8.
  169. Berde CB, Lehn BM, Yee JD, Sethna NF, Russo D. Patient-controlled analgesia in children and adolescents: a randomized, prospective comparison with intramuscular administration of morphine for postoperative analgesia. J Pediatr. 1991 Mar; 118(3):460-6.
  170. Vieyra MA, Masek BJ, Berde CB, Allen GA. Children's pain and family functioning: a comparative analysis. J. Pain and Symptom Management. 1991; 6:146.
  171. Yee JD, Berde CB. Methylphenidate or dextraamphetamine as adjuvants in opioid analgesia. Journal of Pain and Symptom Management. 1991; 6:162.
  172. Masters DB, Dutta S, Langer R, Berde CB. Porlonged sciatic nerve blockade using sustained release of bupivicaine from a biodegradable polymer matrix. Anesthesiology. 1991; 75:A765.
  173. Cahill C, Gondek E, Stafford MA, Sethna NF, Berde CB. Implementation of a PCA program. Journal of Pain and Symptom Management. 1991; 6:187.
  174. Stafford MA, Cahill C, Schwartz T, Yee JD, Sethna NF, Berde CB. Recognition and treatment of pain in pediatric patients with AIDS. Journal of Pain and Symptom Management. 1991; 6:162.
  175. Beyer JE, Berde CB, Bournaki MC. Memories of pain in three- to seven-year-old children. Journal of Pain and Symptom Management. 1991; 6:174.
  176. Henderson KH, Sethna NF, Berde CB. Continuous caudal anesthesia with 2-chloroprocaine for premature infants undergoing inguinal hernia repair. Anesthesiology. 1991; 75:A693.
  177. Sethna NF, Stafford MA, Berde CB. Experience with 852 epidural infusions in a children's hospital. Journal of Pain and Symptom Management. 1991; 6:164.
  178. Wilder RT, Berde CB, Wolohan M, Micheli LM, Vieyra MA. Reflex sympathetic dystrophy in children and adolescents: follow-up of 70 patients adn development of a treatment algorithm. Anesthesiology. 1991; 75:A916.
  179. Beyer JE, McGrath PJ, Berde CB. Discordance between self-report and behavioral pain measures in children aged 3-7 years after surgery. J Pain Symptom Manage. 1990 Dec; 5(6):350-6.
  180. Berde CB, Sethna NF, Fisher DE, Kahn CH, Chandler P, Grier HE. Celiac plexus blockade for a 3-year-old boy with hepatoblastoma and refractory pain. Pediatrics. 1990 Nov; 86(5):779-81.
  181. Berde C, Ablin A, Glazer J, Miser A, Shapiro B, Weisman S, Zeltzer P. American Academy of Pediatrics Report of the Subcommittee on Disease-Related Pain in Childhood Cancer. Pediatrics. 1990 Nov; 86(5 Pt 2):818-25.
  182. Berde CB, Sethna NF, Conrad LS, Hershenson MB, Shillito J. Subarachnoid bupivacaine analgesia for seven months for a patient with a spinal cord tumor. Anesthesiology. 1990 Jun; 72(6):1094-6.
  183. Berde CB, Yee JD, Lehn BM, Moore LJ, Sethna NF. Patient-controlled analgesia in children and adolescents: a randomized comparison with intramuscular morphine. Anesthesiology. 1990; 73:A1102.
  184. Holzman RS, Pascucci RV, Sethna NF, Berde CB. Hypotension, flushing and bronchospasm in myelodysplasia patients undergoing surgery. Section on Anesthesiology, American Academy of Pediatrics. 1990; Spring.
  185. Berde CB, Sethna NF, Yemen TA, Pullerits J, Miler V. Continuous epidural bupivacaine-fentanyl infusions in children following ureteral reimplantation. Anesthesiology. 1990; 73:A775.
  186. Perillo M, Sethna NF, Berde CB. Isoproterenol for test dosing in pediatric regional blockade. Anesthesiology. 1990; 73:A1127.
  187. Berde CB, Masters DB, Dutta S, Turek T, Langer R. Sustained release of dibucaine from a biodegradable polymer matrix: a potential method for prolonged neural blockade. Anesthesiology. 1990; 73:A776.
  188. Berde CB. Regional analgesia in the management of chronic pain in childhood. J Pain Symptom Manage. 1989 Dec; 4(4):232-7.
  189. Anderson CT, Berde CB, Sethna NF, Pribaz JJ. Meningococcal purpura fulminans: treatment of vascular insufficiency in a 2-yr-old child with lumbar epidural sympathetic blockade. Anesthesiology. 1989 Sep; 71(3):463-4.
  190. Shannon M, Berde CB. Pharmacologic management of pain in children and adolescents. Pediatr Clin North Am. 1989 Aug; 36(4):855-71.
  191. Berde CB. Pediatric postoperative pain management. Pediatr Clin North Am. 1989 Aug; 36(4):921-40.
  192. Chang HM, Berde CB, Holz GG, Steward GF, Kream RM. Sufentanil, morphine, met-enkephalin, and kappa-agonist (U-50,488H) inhibit substance P release from primary sensory neurons: a model for presynaptic spinal opioid actions. Anesthesiology. 1989 Apr; 70(4):672-7.
  193. Berde CB, Fischel N, Filardi JP, Coe CS, Grier HE, Bernstein SC. Caudal epidural morphine analgesia for an infant with advanced neuroblastoma: report of a case. Pain. 1989 Feb; 36(2):219-23.
  194. Scuderi G, Sanders DP, Brustowicz RM, Berde CB, Colin A, Allen J, Healy GB, Hall JE. Postoperative lordoscoliosis causing extrinsic compression of the right main stem bronchus and respiratory insufficiency. A case report. Spine (Phila Pa 1976). 1989 Jan; 14(1):110-4.
  195. Berde CB, Sethna NF, Levin L, Retik A, Millis M, Lillehei C, Micheli L. Regional analgesia on pediatric medical and surgical wards. Intensive Care Med. 1989; 15 Suppl 1:S40-3.
  196. Berde C, Sethna NF, Masek B, Fosburg M, Rocklin S. Pediatric pain clinics: recommendations for their development. Pediatrician. 1989; 16(1-2):94-102.
  197. Holzman R, Sethna NF, Berde CB. Spinal vs. general anesthesia in infants undergoing hernia repair. Section on Anesthesiology, American Academy of Pediatrics. 1989.
  198. Vieyra M, Masek BJ, Berde CB. Reflex sympathetic dystrophy in children and adolescents. Society for Behavioral Medicine. 1989.
  199. Lunn RJ, Berde CB, Sethna NF, Johnson C, Gonzalez M. Stellate ganglion blockade in children and adolescents. Anesthesiology. 1989; 71:A1023.
  200. Desparmet J, Berde CB, Schwartz D, Lunn RJ, Hershenson M. Epidural test dosing in halothane-anesthesized lambs. Anesthesiology. 1989; 72:A1022.
  201. Berde CB, Warfield CA. Pediatric pain management. Hosp Pract (Off Ed). 1988 May 30; 23(5A):83-4, 89, 93-4 passim.
  202. Colin AA, Allen JL, Berde CB, Griscom NT, Hall JE, Young LW. Radiological case of the month. Bronchial compression and ventilatory dysfunction in scoliosis. Am J Dis Child. 1988 May; 142(5):545-6.
  203. Berde CB, Holzman RS, Sethna NF, Dickerson RB, Brustowicz RM. A comparison of methadone and morphine for postoperative analgesia in children and adolescents. Anesthesiology. 1988; 69:A768.
  204. Berde CB, Sethna NF, Micheli LJ. A technique for continuous lumbar sympathetic blockade for severe reflex sympathetic dystrophy in children and adolescents. Anesth Analg. 1988; 67:S4.
  205. Berde CB, Lacouture PG, Masek BJ, Sethna NF. Initial experience with a multidiscplinary pediatric pain treatment service. Pain. 1987; Supplement 4:S99.
  206. Berde CB, Sethna NF, Holzman RS, Reidy P, Gondek E. Pharmacokinetics of methadone in children and adolescents in the perioperative period. Anesthesiology. 1987; 67:A519.
  207. Berde CB, Sethna NF. Regional anesthetic approaches to post-operative pain in children and adolescents. Intensive Care Med. 1987; 13:460.
  208. Chang HM, Berde CB, Holz GG, Steward GF, Kream RM. Opioids inhibit substance P release from cultured dorsal root ganglia: a model for spinal narcotic action. Anesthesiology. 1987; 67:A388.
  209. Badwey JA, Curnutte JT, Robinson JM, Berde CB, Karnovsky MJ, Karnovsky ML. Effects of free fatty acids on release of superoxide and on change of shape by human neutrophils. Reversibility by albumin. J Biol Chem. 1984 Jun 25; 259(12):7870-7.
  210. Simmons CF, Winter HS, Berde C, Schrater F, Humphrey GB, Rosen FS, Beaver PC, Weller PF. Zoonotic filariasis with lymphedema in an immunodeficient infant. N Engl J Med. 1984 May 10; 310(19):1243-5.
  211. Berde CB, Benitz WE, Rasmussen LF, Kerner JA, Johnson JD, Wennberg RP. Bilirubin binding in the plasma of newborns: critical evaluation of a fluorescence quenching method and comparison to the peroxidase method. Pediatr Res. 1984 Apr; 18(4):349-54.
  212. Karnovsky ML, Badwey JA, Curnutte JT, Robinson JM, Berde CB, Karnovsky MJ. Some functional effects of physical changes in the membranes of white cells. Kroc Found Ser. 1984; 16:111-27.
  213. Karnovsky ML, Badwey JA, Curnutte JT, Robinson JM, Berde CB, Karnovsky MJ. The excitable membrane of phagocytic leukocytes. Prog Clin Biol Res. 1984; 164:347-54.
  214. Berde C, Willis DC, Sandberg EC. Pregnancy in women with pseudoxanthoma elasticum. Obstet Gynecol Surv. 1983 Jun; 38(6):339-44.
  215. Coolbear KP, Berde CB, Keough KM. Gel to liquid-crystalline phase transitions of aqueous dispersions of polyunsaturated mixed-acid phosphatidylcholines. Biochemistry. 1983 Mar 15; 22(6):1466-73.
  216. Badwey JA, Curnutte JT, Berde CB, Karnovsky ML. Cytochalasin E diminishes the lag phase in the release of superoxide by human neutrophils. Biochem Biophys Res Commun. 1982 May 14; 106(1):170-4.
  217. Berde CB, Coolbear KP, Keough KMW. Phase transitions of dispersions of polyunsaturated mixed acid phosphatidyl cholines: calorimetric measurements and a statistical-mechanical description. Mackinac Conference on Artificial Surfactant Proceedings. 1982.
  218. Kerner JA, Cassani C, Hurwitz R, Berde CB. Monitoring intravenous fat emulsions in neonates with the fatty acid/serum albumin molar ratio. JPEN J Parenter Enteral Nutr. 1981 Nov-Dec; 5(6):517-8.
  219. Berde CB, Andersen HC, Hudson BS. A theory of the effects of head-group structure and chain unsaturation on the chain melting transition of phospholipid dispersions. Biochemistry. 1980 Sep 02; 19(18):4279-93.
  220. Berde CB, Kerner JA, Johnson JD. Use of the conjugated polyene fatty acid, parinaric acid, in assaying fatty acids in serum or plasma. Clin Chem. 1980 Jul; 26(8):1173-7.
  221. Berde CB, Nagai M, Deutsch HF. Human alpha-fetoprotein. Fluorescence studies on binding and proximity relationships for fatty acids and bilirubin. J Biol Chem. 1979 Dec 25; 254(24):12609-14.
  222. Berde CB, Hudson BS, Simoni RD, Sklar LA. Human serum albumin. Spectroscopic studies of binding and proximity relationships for fatty acids and bilirubin. J Biol Chem. 1979 Jan 25; 254(2):391-400.
  223. Berde CB, Rasmussen F, Benitz W, Kerner JA, Johnson JD, Wennberg R. Binding of bilirubin and fatty acids in the sera of neonates. Clin Res. 1979; 27:134A.
  224. Daan S, Berde C. Two coupled oscillators: simulations of the circadian pacemaker in mammalian activity rhythms. J Theor Biol. 1978 Feb 06; 70(3):297-313.
  225. Berde CB, Kerner JA, Johnson JD. A free fatty acid binding index for serum. Pediatr Res. 1978; 12:502.
  226. Berde CB, Heller RA, Simoni RD. Activation of purified 3-hydroxy-3-methylglutaryl-CoA reductase by phospholipids. Biochim Biophys Acta. 1977 Jul 20; 488(1):112-20.
  227. Berde C. A population-family planning resource center: a community educational service. Fam Plann Resume. 1977; 1(1):142-3.
  228. Berde C. Nonmonotonic transients and some mathematical models of circadian rhythms. J Theor Biol. 1976 Feb; 56(2):435-41.
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