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Research Fellowship Opportunities

Postdoc in the Division of Infectious Diseases/Department of Medicine at Boston Children’s Hospital

Job description

The Levy Laboratory is the focal point of the Precision Vaccines Program at Boston Children’s Hospital/Harvard Medical School. The Program employs cutting edge technologies to understand age-specific features of immune responses to inform development of vaccines tailored for optimal safety and immunogenicity towards distinct populations. Due to distinct immunity, most infection-induced death occurs at the extremes of life motivating development of improved vaccines that are safe and effective in the young and old. We seek a skilled and motivated post-doctoral scientist with background in Immunology (experience in T and B lymphocyte studies a plus), Vaccinology, and/or Systems Biology and Bioinformatics to lead projects employing systems biology to characterize age-specific vaccine responses and development of novel adjuvanted vaccines. The project will employ recent knowledge in the areas of innate immune pathways (TLRs/inflammasome) and nanoparticle technology to identify adjuvants and enhance immune responses of those at the extremes of age in vitro and in vivo. Studies will employ in vitro modeling of human newborn, adult and elderly antigen-presenting cells, T and B lymphocytes as well as in vivo animal and human studies.

Our laboratory, comprised of 12 current members including post-doctoral scientists, clinical fellows and technicians, is dynamic, international, supportive and productive. We are well funded by NIH, Gates Foundation, internal support as well as multiple sponsored research agreements. We offer excellent opportunities for high impact research, publication, attendance at scientific meetings, and careeradvancement with graduates of the lab holding prominent positions in academia and industry. The candidate should have obtained their PhD within the last 1-3 years. Interested applicants should e-mail their CV and arrange to have 3 statements of reference e-mailed to: ofer.levy@childrens.harvard.edu.

A postdoctoral fellow position is available in the Epigenetics and Stem Cell Unit of the Laboratory of Translational Gerontology Branch, National Institute on Aging (NIA), National Institutes of Health (NIH).

Specific interests of the laboratory encompass defining mechanisms that underlie age associated changes of the hematopoietic stem cell compartment with a focus on epigenetic drivers and DNA damage.

Candidates should have a Ph.D. M.D. or D.V.M. with 0-3 years post-doc experience. 

  • Strong oral and written communication skills are a requirement
  • Expertise working with lenti-viruses and CRISPR/Cas9 technology is desirable, but more importantly, we are seeking team members with
  • a strong work ethic and the aspiration to understand mechanisms driving tissue-specific stem cell
  • phenotypes. 

Please visit https://scholar.google.com/citations?user=xDwht4QAAAAJ&hl=en for more information on the research interests of our group

Applicants should submit their CV including a list of publications, a cover letter containing a brief statement of how his/her expertise can contribute to the research on aging hematopoietic stem cells (<1 page), and the name and contact information of three references to: 

Isabel Beerman, Ph.D., at isabel.beerman@nih.gov

Candidates may need to complete an on-site interview process to present her/his data and meet with our current group members. The Institute’s dynamic research environment encourages trainees to collaborate with the over 12,000 resource-rich NIH labs focused on basic, translational, and clinical research. 

Though the position is free from the demands of obtaining grants and teaching, opportunities to do both are available

Salary is commensurate with experience and accomplishments, and also includes benefits such as health insurance for the trainee and his/her family, support for coursework related to the trainee's research, opportunities to present research at national/international meetings. In addition, the NIH Fellows Committee (FelCom) and the NIH Office of Intramural Training & Education (OITE) sponsor a wide range of career development programs.

DHHS and NIH are Equal Opportunity Employers. The NIH is dedicated to building a diverse community in its training and employment programs

Postdoctoral Fellowship in Vascular Biology and Genetics at Harvard Medical School

The D’Amato Lab of the Vascular Biology Program at Boston Children’s Hospital and Harvard Medical School is seeking a highly motivated post-doctoral researcher to study the genetic control of ocular angiogenesis. The project investigates candidate genes found to control angiogenesis in the mouse eye. These candidate genes were identified through genome-wide association studies (GWAS) of inbred mouse strains and further validated in zebrafish. The fellow will lead a program to verify and elucidate the mechanism of action of these genes. The ideal postdoc (MD or PhD) will have a strong background in molecular and mammalian genetics with an interest in vascular biology and ophthalmology. Candidates should be able to work independently and have strong English writing skills. Salary is commensurate with experience. Position is available immediately for two years with potential for renewal and is fully funded with benefits. 

If interested, please send via email a CV, a statement of research interests, as well as the names and contact information for three references to:

Dr. Robert D'Amato 
Vascular Biology Program 
Boston Children's Hospital
300 Longwood Ave
Boston, MA 02115

robert.damato@childrens.harvard.edu

Lab website: www.damatolab.com

Senior Research Director

Department Stem Cell Program; Medicine-Hematology/Oncology

Description:
Senior Research Director, George Daley Laboratory; http://daley.med.harvard.edu
Seeking a talented scientist to supervise a dynamic translational hematology research
laboratory at Boston Children’s Hospital and the Harvard Medical School. This position supports
the principal investigator in managing scientific operations, maintaining regulatory compliance,
and performing research and administrative functions. The position calls for a conscientious,
creative, adaptable individual with good writing skills, and is well suited to the ambitious
individual who wishes to remain active in biomedical research as a career scientist in a
supervisory role. Outstanding candidates will be considered for faculty appointment as
Instructor at Boston Children’s Hospital and Harvard Medical School.


Duties and responsibilities will include:

• Participating in scientific group meetings, strategic planning, grant writing, and publications;
• Assisting principal investigator in managing personnel, projects, and research infrastructure;
• Supervising research technician staff and routine laboratory operations such as
ordering/receiving, inventory, vivarium coverage, and special projects;
• Liaison to institutional officials/offices including laboratory and radiation safety, research
operations, human resources, animal welfare, facilities and maintenance, occupational health
and safety, sponsored projects, public affairs, government affairs, intellectual property,
general counsel, and fund raising (Foundation and Trust);
• Recruitment and mentoring of research and administrative staff;
• Generation and maintenance of regulatory approvals including human subjects (IRB),
laboratory animals (IACUC), biosafety (IBC), and human embryonic stem cells (ESCRO);
• Operational understanding of standard laboratory equipment including freezers, tissue
culture hoods, incubators, FACS machines, microscopes, and computers among others;
• Maintenance of publication-related reporting and deposition requirements including
PubMedCentral, NIHMS, and MyNCBI;
• Monitoring of laboratory e-mail account and responding as needed to inquiries regarding
available positions, tissue donation, reagents requests, and other areas;
• Maintenance of laboratory website (experience with Dreamweaver, Photoshop and Illustrator
helpful);
• Drafting and review of sections of grant funding applications and progress reports pertinent to
budget justification, vertebrate animals, human subjects, facilities/infrastructure, and key
personnel;
• Editing of manuscripts, funding applications, and other laboratory-related submissions;
• Strategic planning regarding capital equipment requisitions, purchases, and space allocation;
• Ability to contribute to ongoing research projects as needed;

Requirements:
• Advanced Degree; MD or PhD in a related discipline
• At least 5 years of post-doctoral research experience
• Excellent oral and written communication skills

Please forward CV and three references to Dr. George Daley, Boston Children's Hospital, 1
Blackfan Circle, 7th Floor, Boston, MA 02115; Tel: 617-919-2015;
Daley.Lab@childrens.harvard.edu

Status Full Time - 40 Hours Shift Day

Schedule Mon-Fri and occasional weekends as needed


Genetics Postdoctoral Fellowship

Boston Children’s Hospital
Broad Institute of Harvard and MIT
Harvard Medical School
Boston, MA

A genetics postdoctoral training fellowship is available to work in the laboratory of Elizabeth Engle MD,
Professor of Neurology and Ophthalmology at Harvard Medical School (HMS) and an HHMI Investigator at
Boston Children’s Hospital (BCH), in collaboration with the laboratory of Daniel MacArthur PhD, Assistant
Professor of Genetics at HMS and Associate Director of Medical and Populations Genetics at the Broad
Institute and Mass General Hospital.

Background/Project
Dr. Engle is a neurogeneticist and developmental neurologist whose lab has defined a series of congenital
syndromes that perturb cranial nerve development and result in disorders of eye and face movement, while
Dr. MacArthur is a leader in the genomic analysis of large datasets in the context of rare disease, with a
particular focus on neuromuscular disorders. The goal of their collaborative translational research is to identify
and functionally study novel genetic causes of syndromic congenital cranial nerve disorders through analysis of
whole genome sequence (WGS) data from 900 individuals (a cohort of the Gabriella Miller Kids First Pediatric
Research Program).

Collaboration/Location
The postdoctoral fellow will be supervised by Drs. Engle and MacArthur; home base will be in the Engle lab and
the fellow will work closely with members of both the Engle and MacArthur research teams. The fellow will
have ample opportunities to take advantage of the vibrant scientific community of BCH, HMS and its affiliated
hospitals, and the Broad, and will likely interact with other investigators participating in the Gabriella Miller
Kids First Pediatric Research Program, supported by the NIH Common Fund.

Requirements
The ideal candidate will be highly motivated and creative with the ability to learn quickly and to function both
independently and within a team. S/he should also have:
• Ph.D. and/or M.D. training in genetics/genomics or a related field
• Expertise working with next-generation sequence data
• Preferred background in neurodevelopment
• Proven research productivity as demonstrated in publications
• Excellent written and oral communication skills

How to Apply
Please submit the following documents:
1. Cover letter
2. Curriculum vitae
3. Summary of your research experience and interests
4. Reference list including contact information (minimum of 3)

Please compile all the documents into one PDF in the order listed above and email to
engle.admin@childrens.harvard.edu.


Stem Cell Scientist

Location: South San Francisco, CA, USA

Summary: Senti Bio is seeking talented stem cell biologists to contribute to our early stage

projects, including the translation of novel technologies, protocol/process development, and

generation of pre-clinical data on key disease indications related to engineering of human stem

cells. A successful applicant will be able to independently drive a high risk/high impact research

program, work collaboratively with the broader scientific and business team to meet

milestones, and play a key role in building the culture of the company as it grows. Applicants

should have current knowledge of stem cell culture and differentiation tools and methods as

well as a mindset to deliver robust and practical solutions for long term commercial impact. We

are seeking individuals who are passionate about the future of “smart therapeutics” and have

the energy and boldness to thrive and grow in a startup environment.

Responsibilities:

  • Plan, perform, and interpret scientific experiments in a laboratory setting
  • Provide technical expertise and leadership in multiple parallel projects
  • Prepare regular presentations to the broader business and strategic team
  • Stay current with advanced molecular methods, scientific literature, and participate in

ideation and decision making meetings

  • Lead and propose “mini-projects” as needed, such as assessment of novel methods or

applications

  • Assist in milestone planning, budgeting, and team building/training

Qualifications:

  • Ph.D. or equivalent with expertise in stem cell biology or cell engineering
  • At least 2 years of stem cell engineering (ESC, iPSC, MSC, HSC), preferably for

therapeutic applications

  • Proficient with cell culture, cell analysis, and flow cytometry and analysis
  • Demonstrated ability to work independently and as part of a multi-functional team
  • Experience with in vivo animal studies a plus
  • Prior experience in a startup or industry role in therapeutic drug development a plus

Salary and Benefits:

  • Base pay, bonuses, and benefits to be determined based on application qualifications

with the aim of being competitive with similar roles in the area

  • Significant growth opportunity as the company expands

About: Senti Biosciences is a pioneering biotechnology startup developing novel therapeutics to

solve challenging and complex diseases. Founded in 2016 from an all-star team of synthetic

biologists from leading universities, Senti is creating world-class capabilities to design and

develop therapeutic cell circuits to improve human health. Headquartered in the San Francisco

Bay Area, Senti leverages expertise in bio-engineering and biological programming to build the

future of gene and cell based therapies.

To Apply:

Send an email with resume and cover letter to: jobs@sentibio.com

Assistant Professor of Biology: Infectious Disease, Oberlin College

The Oberlin College, Department of Biology invites applications for full-time tenure-track faculty position in Infectious Disease, beginning July 1, 2017

We seek individuals with expertise in immunology, parasitology, epidemiology, or a similar field, and in social factors that affect how disease is experienced. The incumbent will teach the standard teaching load (currently 4.5 courses per year), including upper-level courses in infectious disease, introductory biology, and a non-majors course; mentor undergraduate research students;  engage in scholarly research; and participate in the full range of faculty responsibilities, including academic advising and committee service. 

Successful experience working with, teaching, or mentoring diverse groups is desirable. To be assured of consideration, submit a letter of application, a curriculum vitae, academic transcripts, and at least three recent letters of reference to 

https://jobs.oberlin.edu/postings/3239 by 17 October 2016


University of Sydney Cardiovascular Fellowship 2017

The Heart Research Institute (HRI) and the Charles Perkins Centre of the University of Sydney are seeking
exceptional national and international early to mid-career researchers with the potential to become global leaders
in cardiovascular research for the Sydney Cardiovascular Fellowships 2017.

These fellowships represent the most prestigious fellowships in Australia for early to mid-career cardiovascular
researchers, and are valued at $1,000,000 over a period of five years.

The HRI, in partnership with the Charles Perkins Centre, University of Sydney, Royal Prince Alfred Hospital, and
affiliated Medical Research Institutes represent the largest consortium of cardiovascular researchers in Australia.
The $500 million investment in the Charles Perkins Centre by the University of Sydney represents one of the
largest single investments in diabetes, obesity, and CV research globally.

Successful applicants will interact closely with the following research expertise already present at the HRI and Charles Perkins Centre research consortium:
Atherosclerosis and its complications
  • Vascular biology and thrombosis
  • Cardiometabolic disease
  • Cardiovascular tissue engineering and biomaterials
  • Cardiovascular genetics and sudden cardiac death
  • Thromboembolic diseases in diabetes and cancer
Applicants performing research in these or complementary areas will be considered.

For more information and to download detailed information on these fellowships visit http://scvrc.org.au/ 

Timeline
Starting date for expressions of interest September 2016
Closing date for expressions of interest 14 October 2016
Candidates shortlisted and notified 18 November 2016
Shortlisted applicants first interview (Teleconference) Late November/early December 2016
Final applicant interviews (Sydney) January 2017


Aldovini lab:Division of Infectious Diseases at Boston Children's Hospital and Harvard Medical School

A postdoctoral position is available in the Division of Infectious Diseases at Boston Children’s Hospital and Harvard Medical School to support in a research program on HIV biology and AIDS vaccine development. Highly motivated applicants must have a PhD or MD degree, strong experience in molecular biology and/or immunology techniques and good communication skills. 

Send curriculum vitae with names and addresses of three references to Dr. Anna Aldovini: anna.aldovini@childrens.harvard.edu

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