Research

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2015

Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown
Wittrup, A., Ai, A., Liu, X., Hamar, P., Trifonova, R., Charisse, K., Manoharan, M., Kirchhausen, T. and Lieberman, J. Nature biotechnology. 2015, 33. 8. 870-876. (PDF)

Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics
Li, D., Shao, L., Chen, B. C., Zhang, X., Zhang, M., Moses, B., Milkie, D. E., Beach, J. R., Hammer, J. A., 3rd, Pasham, M., Kirchhausen, T., Baird, M. A., Davidson, M. W., Xu, P. and Betzig, E. Science. 2015, 349. 6251. aab3500. (PDF)

Endocytosis of ligand activated sphingosine 1-phosphate receptor 1 mediated by the clathrin-pathway. 
Reeves, P. M., Kang, Y. L. and Kirchhausen, T. Traffic. 2015 PMID: 26481905  (PDF)

Superinfection exclusion is absent during acute Junin virus infection of Vero and A549 cells.
Gaudin, R. and Kirchhausen, T. 2015.  Scientific reports. 2015,  5. 15990. (PDF)

Asymmetric formation of coated pits on dorsal and ventral surfaces at the leading edge of motile cells and on protrusions of immobile cells.
Kural C, Akatay AA, Gaudin R, Chen BC, Legant WR, Betzig E, Kirchhausen T. Mol Biol Cell. 2015 Apr 7. 

26(11):2044-53

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Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology.
Ishikawa Y, Maeda M, Pasham M, Aguet F, Tacheva-Grigorova SK, Masuda T, Yi H, Lee SU, Xu J, Teruya-Feldstein J, Ericsson M, Mullally A, Heuser J, Kirchhausen T, Maeda T. Haematologica. 2015 Apr;100(4):439-51. (PDF)

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