Research

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2015

Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I
Xu J, Mercado-Lopez X, Grier JT, Kim WK, Chun LF, Irvine EB, Del Toro Duany Y, Kell A, Hur S, Gale M Jr, Raj A, Lopez CB.
MBio.(2015) 6:e01265-15.  (PDF)

Unusual cutaneous features associated with a heterozygous gain-of-function mutation in IFIH1: Aicardi-Goutires-Singleton-Merten overlapping syndrome.
Bursztejn AC, Briggs TA, Del Toro Duany Y, Anderson BH, O'Sullivan J, Williams SG, Bodemer C, Fraitag S, Gebhard F, Leheup B, Lemelle I, Oojageer A, Raffo E, Schmitt E, Rice GI, Hur S, Crow YJ.,  Br J Dermatol. Epub ahead of print.

Helicases in antiviral immunity: dual properties as sensors and effectors
Ahmad S and Hur S, .
Trends in Biochemical Sciences (2015) 40:576-85. (Review) (PDF)

Measuring Monomer-to-Filament Transition of MAVS as an In Vitro Activity Assay for RIG-I-Like Receptors
Wu B, Houh Y & Hur S, ,
Methods Molecular Biology, Vol 1390, In Press, (Book Chapter)

How RIG-I like receptors activate MAVS
Wu B & Hur S. Curr. Opin. Virol. (2015) 12:91-8 (PDF)

ATP-Dependent Effector-like Functions of RIG-I-like Receptors.
Yao H, Dittmann M, Peisley A, Hoffmann HH, Gilmore RH, Schmidt T, Schmid-Burgk JL, Hornung V, Rice CM, Hur S.
Mol Cell. 2015 Apr 16. pii: S1097-2765(15)00179-3. (PDF)

MDA5-filament, dynamics and disease.
Del Toro Duany Y, Wu B, Hur S. Curr Opin Virol. 2015 Feb 9;12C:20-25. (PDF)
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