Research

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2009

The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation.
Banno F, Chauhan AK, Kokame K, Yang J, Miyata S, Wagner DD, Miyata T.
Blood. 2009;113(21):5323-5329. PMCID: 2686194.

Differential stimulation of monocytic cells results in distinct populations of microparticles.
Bernimoulin M, Waters EK, Foy M, Steele BM, Sullivan M, Falet H, Walsh MT, Barteneva N, Geng JG, Hartwig JH, Maguire PB, Wagner DD.
J Thromb Haemost. 2009;7(6):1019-1028. PMCID: 3242443.

Oxidative stress activates ADAM17/TACE and induces its target receptor shedding in platelets in a p38-dependent fashion.
Brill A, Chauhan AK, Canault M, Walsh MT, Bergmeier W, Wagner DD.
Cardiovasc Res. 2009;84(1):137-144. PMCID: 2741344.

Inhibition of von Willebrand factor-mediated platelet activation and thrombosis by the anti-von Willebrand factor A1-domain aptamer ARC1779.
Diener JL, Daniel Lagasse HA, Duerschmied D, Merhi Y, Tanguay JF, Hutabarat R, Gilbert J, Wagner DD, Schaub R.
J Thromb Haemost. 2009;7(7):1155-1162.

Serotonin stimulates platelet receptor shedding by tumor necrosis factor-alpha-converting enzyme (ADAM17).
Duerschmied D, Canault M, Lievens D, Brill A, Cifuni SM, Bader M, Wagner DD.
J Thromb Haemost. 2009;7(7):1163-1171. PMCID: 3244876.

Structure, biology and genetics of von Willebrand factor.
Ginsburg D, Wagner DD. In: Hoffman R, Benz EJ, Shattil SJ, Furie B, Silberstein LE, McGlave P, Heslop H, editors.
Hematology: Basic Principles and Practices. 5th ed. New York: Churchill Livingstone; 2009.

Innate immune cells induce hemorrhage in tumors during thrombocytopenia.
Ho-Tin-Noe B, Carbo C, Demers M, Cifuni SM, Goerge T, Wagner DD.
Am J Pathol. 2009;175(4):1699-1708. PMCID: 2751565.

Platelets: guardians of tumor vasculature. 
Ho-Tin-Noe B, Goerge T, Wagner DD. 
Cancer Res. 2009;69(14):5623-5626.

Elevated levels of soluble P-selectin in mice alter blood-brain barrier function, exacerbate stroke, and promote atherosclerosis.
Kisucka J, Chauhan AK, Zhao BQ, Patten IS, Yesilaltay A, Krieger M, Wagner DD.
Blood. 2009;113(23):6015-6022. PMCID: 2700332.

Inhibition of VEGF or TGF-{beta} signaling activates endothelium and increases leukocyte rolling.
Walshe TE, Dole VS, Maharaj AS, Patten IS, Wagner DD, D'Amore PA.
Arterioscler Thromb Vasc Biol. 2009;29(8):1185-1192. PMCID: 2775449.

von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke.
Zhao BQ, Chauhan AK, Canault M, Patten IS, Yang JJ, Dockal M, Scheiflinger F, Wagner DD.
Blood. 2009;114(15):3329-3334. PMCID: 2759655

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