Research

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2006

The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis.
Bergmeier W, Piffath CL, Goerge T, Cifuni SM, Ruggeri ZM, Ware J, Wagner DD.
Proc Natl Acad Sci U S A. 2006;103(45):16900-16905. PMCID: 1636551.

Inflammation. In: Michelson A, editor. Platelets.
Bergmeier W, Wagner D.
2nd ed. San Diego: Elsevier-Academic Press; 2006.

Systemic antithrombotic effects of ADAMTS13.
Chauhan AK, Motto DG, Lamb CB, Bergmeier W, Dockal M, Plaimauer B, Scheiflinger F, Ginsburg D, Wagner DD.
J Exp Med. 2006;203(3):767-776. PMCID: 2118248.

Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy.
Hirahashi J, Mekala D, Van Ziffle J, Xiao L, Saffaripour S, Wagner DD, Shapiro SD, Lowell C, Mayadas TN.
Immunity. 2006;25(2):271-283.

Elevated levels of homocysteine compromise blood-brain barrier integrity in mice.
Kamath AF, Chauhan AK, Kisucka J, Dole VS, Loscalzo J, Handy DE, Wagner DD.
Blood. 2006;107(2):591-593. PMCID: 1895614.

Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage.
Kisucka J, Butterfield CE, Duda DG, Eichenberger SC, Saffaripour S, Ware J, Ruggeri ZM, Jain RK, Folkman J, Wagner DD.
Proc Natl Acad Sci U S A. 2006;103(4):855-860. PMCID: 1348013.

Decreased plasma fibronectin leads to delayed thrombus growth in injured arterioles.
Matuskova J, Chauhan AK, Cambien B, Astrof S, Dole VS, Piffath CL, Hynes RO, Wagner DD.
Arterioscler Thromb Vasc Biol. 2006;26(6):1391-1396.

The A2B adenosine receptor protects against inflammation and excessive vascular adhesion.
Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M, Jones MR, St Hilaire C, Seldin DC, Toselli P, Lamperti E, Schreiber BM, Gavras H, Wagner DD, Ravid K.
J Clin Invest. 2006;116(7):1913-1923. PMCID: 1483170.

Fibrinogen and von Willebrand factor-independent platelet aggregation in vitro and in vivo.
Yang H, Reheman A, Chen P, Zhu G, Hynes RO, Freedman J, Wagner DD, Ni H.
J Thromb Haemost. 2006;4(10):2230-2237.

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