Research

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PK Lab | Publications

  • Goobie SM, Meier PM, Pereira LM, McGowan FX, Prescilla RP, Scharp LA, Rogers GF, Proctor MR, Meara JG, Soriano SG, Zurakowski D, Sethna NF: Efficacy of tranexamic acid in pediatric craniosynostosis surgery. A double-blind placebo controlled trial. Anesthesiology 2011; 114(4): 862-71

  • Goobie SM, Meier PM, Sethna NF, Soriano SG, Zurakowski D, Samant S, Pereira LM: Population pharmacokinetics of tranexamic acid in paediatric patients undergoing craniosynostosis surgery. Clin Pharmacokinet; 2013; 52: 267-76

  • Bu, W., Pereira, L. M., Eckenhoff, R. G., & Yuki, K. (2014). Stereoselectivity of isoflurane in adhesion molecule leukocyte function-associated antigen-1. PloS One, 9(5), e96649.

  • Khwaja, O. S., Ho, E., Barnes, K. V., O'Leary, H. M., Pereira, L. M., Finkelstein, Y., Nelson, C. A., Vogel-Farley, V., DeGregorio, G., Holm, I. A., Khatwa, U., Kapur, K., Alexander, M. E., Finnegan, D. M., Cantwell, N. G., Walco, A. C., Rappaport, L., Gregas, M., Fichorova, R. N., Shannon, M. W., Sur, M., & Kaufmann, W. E. (2014). Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome. Proceedings of the National Academy of Sciences of the United States of America, 111(12), 4596-4601.

  • Goobie SM, Meier PM, Pereira LM, Soriano SG, Zurakowski D, Sethna NF. Population pharmacokinetic modeling of tranexamic acid in children undergoing open craniosynostosis surgery. 2011 Annual Meeting of the American Society of Anesthesiologists. Chicago. October 2011. Poster Discussion. A044.

  • Goobie SM., McCann ME, Brustowicz B, Sethna NF, Hresko T. B Barton, Periera LM Pharmacokinetics of Tranexamic Acid in Pediatric Scoliosis Surgery. The Canadian Anesthesia Society Annual Meeting. Ottawa, Ontario. June 2015

  • Goobie SM, T Hresko, ME McCann, D Hedequist, R Brustowicz, M Glotzbecker, N Sethna, L Karlin, A Navedo, J Emans, B Barton, D Zurakowski, L Pereira. Efficacy and Safety of Tranexamic Acid in Adolescent Idiopathic Surgery. The Scoliosis Research Society Annual Meeting. Indianapolis. 2015.


  • Goobie SM, T Hresko, ME McCann, D Hedequist, R Brustowicz, M Glotzbecker, N Sethna, L Karlin, A Navedo, J Emans, B Barton, D Zurakowski, L Pereira. Using Population Pharmacokinetics of Tranexamic Acid in Pediatric Scoliosis Surgery to predict the Optimum Dose. American Society of Anesthesiology annual meeting San Diego Sept 2015.

  • Sriswasdi P, Dube C, Pereira L,. Berde CB, Goobie SM.  Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Pediatric Surgical Patients. American Society of Anesthesiology annual meeting San Diego Sept 2015
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