What are we doing?
- Comparative effectiveness and interventional clinical trials in pediatric status epilepticus and epileptic encephalopathies
How do we do it?
- Inventing, evaluating and implementing clinically relevant biomarkers and treatment paradigms to assess and benchmark these based on clinical data, neurophysiology, imaging, pharmacogenomics and genetics, in collaboration with basic researchers locally, nationally, and internationally.
- Developing and evaluating monitoring tools for clinical biomarkers to further clinical epilepsy outcome measures including seizure characterization, neuropsychological outcome assessment, and quality of life assessment by means of seizure sensors and electronic tools including TriVox, the RENCI seizure tracking and outcome prediction modeling software, and novel in- and outpatient monitoring devices and algorithms, and neurophysiological, biochemical and genetic periodicity markers and implement these techniques into clinical workflow.
- Research networks and collaborations are essential for our work, like the Pediatric Status Epilepticus Research Group, the Pediatric Epilepsy Research Consortium, the pediatric critical care epilepsy research group, the Critical Care EEG Monitoring Research Consortium, the Pediatric Neurocritical Care Research Group and other consortia.
Click for a full list of Loddenkemper Lab publications on PubMed.