Joined the lab in the fall of 2016 after receiving her Ph.D. from Johns Hopkins school of Medicine. Her thesis was completed under the guidance of Kathryn Wagner M.D. Ph.D. from Johns Hopkins and Kennedy Krieger Institute Genetic Muscle Center in Baltimore, Maryland. While working in Baltimore, Tracy developed a novel xenograft model for human skeletal muscle diseases and tested new gene therapy with the model. Working closely with the muscular dystrophy patients community during her graduate work has motivated her to stay in the field of muscular dystrophy while continuing to work on pushing more therapeutics from bench to clinic. In her spare time, Tracy is passionate about cooking and eating good food while exploring fun things to do around Boston.
Joined the Kunkel Lab in June 2015. She received her Ph.D. from the University of Pennsylvania. Her research in the Kunkel lab is focused on discovering disease modifiers and drug therapies for Duchenne Muscular Dystrophy. Janelle is from Melrose, Massachusetts.
Anna Pakula, Ph.D
Joined the Kunkel Lab in October 2015 after graduating from Adam Mickiewicz University in Poland. She holds a Ph.D. in the myology field from the Free University in Germany. In the Kunkel Lab, Anna’s focus is on Facioscapulohumeral Dystrophy (FSHD) and Duchenne Dystrophy. Her interests include developing treatment strategies through injections and use of transgenic zebrafish models designed by Hiroaki Mitsuhashi. Through Anna’s focus on the main mechanisms behind FSHD, she has been working on Single Cell Transcriptomics on primary human muscle FSHD cells in order to characterize the cells regardless of DUX4 expression. Anna is an active member of the Women in Science Association in both Germany and the United States. In her spare time, Anna enjoys discovering different cultures through her many travels and is Thorn, Poland.
Matthias Lambert, Ph.D.
Joined the lab in the fall of 2017 after receiving his Ph.D. in physiology from Lille University in France. His doctorate research was completed under the supervision of physiologist, Pr. Bruno Bastide and proteomics professor, Dr. Caroline Cieniewski-Bernard. While completing his Ph.D., Matthias focused on the characterization of the role of a post-translational modification, O-GlcNAcylation, in the sarcomere structure of the skeletal muscle and it’s involvement in muscle diseases. Using the C2C12 myotubes model, Matthias determined that O-GlcNAcylation is a fine modulator of the sarcomeric morphology, it is involved in interactions between key structural proteins such as desmin and alpha B-crystallin, and O-GlcNAcylation has O-GlcNAc binding sites on various proteins of interest. In the Kunkel lab, Matthias plans to first use a library of novel small molecules (which modulate different signaling pathways in the zebrafish sapje screening model) to modulate Jagged1 protein and restore dystrophic phenotype as seen in previous animal models. His second goal is to move these efficient molecules into a preclinical mouse model and create and new transgenic mouse line expressing Jagged1 in an inducible way. In his spare time, Matthias enjoys playing the drums while discovering new food and culture from all over the world. He is also an active member of the French Muscular Dystrophy Association. Matthias is from Saint-Omer, France.
Lillian Mead, Research Assistant
Joined the Kunkel lab in October 2015 after completing an undergraduate degree in Biology from Lake Forest College in Chicago. During her undergrad, Lillian worked with Dr. Amiel Rosenkranz at Rosalind Franklin University of Medicine and Science to observe changes in eating habits and stress reactions of female rats injected with progesterone. For the past year, Lillian has been collaborating on a multiple DMD and FSHD lab projects using zebrafish and mouse models. Lilly also assists with the maintenance of the labs muscular dystrophy mouse and fish models. In her spare time, Lilly works at The Handle Bar spin studio and enjoys exploring Boston. Lilly is from Yarmouth, Maine.
Devin Gibbs, Research Assistant
Joined the Kunkel Lab in June of 2014. He completed a double major at Colby College in Biology and Music where he worked in Andrea’s Tildens lab determining the expression patterns of circadian rhythm proteins in crustaceans. For the past two years, one of Devin’s primary roles in the Kunkel Lab has been the maintenance of the labs muscular dystrophy mouse and fish models. Devin has also collaborated on a wide range of projects including drug screens in zebrafish and behavioral assays in mice. Devin is from Waterville, Maine.
*Devin will be joining the Molecular Biology Ph.D. program at UCLA, fall 2017