Research

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Yannik Regimbald-Dumas - PhD

Research Fellow

Yannik received his PhD in Pharmacology from the University of Sherbrooke in Quebec, Canada in 2011. He joined the lab in October 2010 and is currently characterizing the role of a new regulator of Rspondin/b-catenin signaling and self-renewal of intestinal epithelial stem cells.  

Selective Publications:

  • Regimbald-DumasY., He X. (2011). Wnt signalling: What The X@# is WTX?EMBO Journal. 30(8):1415-1417
  • FregeauM-O.,Regimbald-DumasY.,GuillemetteG.(2011). Positive regulationof inositol 1,4,5-trisphosphate-induced Ca2+ release by mammalian  targetof rapamycin (mTOR)inRin-M5F.Journal of Cellular Biochemistry. 112(2):723-733
  • Regimbald-DumasY.,FregeauM-O.,GuillemetteG.(2011).Mammaliantarget ofRapamycin(mTOR)phosphorylatesinositol1,4,5-trisphosphatereceptortype 2and increases its Ca2+releaseactivity. Cellular Signalling. 23(1):71-79
  • Regimbald-Dumas Y., Arguin  G., Fregeau M-O., Guillemette G. (2007). cAMP-dependent  proteinkinaseenhancesinositol1,4,5-trisphosphate-induced Ca2+release in AR4-2J cells. Journal of Cellular Biochemistry. 101(3):609-618.
  • ArguinG.,Regimbald-DumasY.,FregeauM-O.,CaronA.Z.,GuillemetteG. (2007).ProteinkinaseCphosphorylatestheinositol1,4,5-trisphosphatereceptor type2 and decreases themobilization of Ca2+inpancreatoma AR4-2J cells. Journal of Endocrinology. 192(3):659-668.
  • GuillemetteJ.O.,CaronA.Z.,Regimbald-DumasY.,ArguinG.,MigneryG., BoulayG.,GuillemetteG.(2005).Expressionofatruncatedformofinositol1,4,5 trisphosphate receptors typeIII in thecytosolof DT40 triple inositol1,4,5 trisphosphate receptor-knockout cells. Cell Calcium. 37(2):97-104.
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