Research

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Sherin Shaaban

Sherin Shaaban, M.D., Ph.D., Postdoctoral Research Fellow

Sherin joined the Engle lab in February 2010 as a postdoctoral research fellow. She is an Assistant Lecturer in Ophthalmology at the Faculty of Medicine, Mansoura University in Egypt. She received her medical degree and then earned a M.Sc. in Ophthalmology, both from Mansoura University. Following her clinical training, she pursued a Ph.D. at Okayama University in Japan. This degree was awarded in 2009 for clinical genetics research directed at determining susceptibility loci for comitant strabismus using genetic linkage analysis. In the Engle lab, Sherin is using a variety of genetic approaches to elucidate the genetic variants underlying the common forms of strabismus. Sherin will also be working to identify the genetic causes of isolated congenital ptosis. We hypothesize that ptosis is one of the CCDDs and that gene defects might alter the development of the central caudal motor neurons of the oculomotor nucleus and/or the targeting of their axons to the levator palpebrae superioris, which elevates the eyelid.

Publications:

  1. Shaaban S, El-lakkany R, Swelam A, Anwar G. Low vision aids provision for visually impaired Egyptian patients: a clinical outcome. Middle East Afr J Ophthalmol. 2009, 16(1):29-34.
  2. Shaaban S, Matsuo T, Strauch K, et al. Investigation of parent-of-origin effects in comitant strabismus using MOD-score analysis. Mol Vis. 2009, 15:1351-1358.
  3. Shaaban S, Matsuo T, Fujiwara H, Itoshima E, Furuse T, Hasebe S, Zhang Q, Ott J, Ohtsuki H. Chromosomes 4q28.3 and 7q31.2 as new susceptibility loci for comitant strabismus. Invest. Ophthalmol. Vis Sci. 2009, 50(2):654-661.

Awards:

Akagi Award of the Okayama University Ophthalmology Alumni Association, 2010.
International Council of Ophthalmology Fellowship award in Pediatric Ophthalmology and Strabismus, 2009.

Contact information:

Sherin Shaaban, M.D., Ph.D.
Division of Neurology
CLS 14030.10
Children’s Hospital Boston
300 Longwood Avenue
Boston, MA, 02115
E-mail: sherin.shaaban@childrens.harvard.edu

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