Your participation in the study should take no more than an hour. There is no fee for you to participate, as the costs associated with this study are covered by research funds.
Potential study participants will be identified from Ophthalmology Department medical records/via schedules for upcoming appointments and contacted by mail. They will be sent an introductory letter and if interested in enrolling, the individual and his/her family will be invited to enroll on the day of their next scheduled routine appointment at Boston Children's Hospital.
For each participant, a full medical and family history will be obtained and any associated systemic abnormalities will be documented. Each affected individual will undergo evaluation of best-corrected visual acuity, external examination, visual fields, pupils, cycloplegic retinoscopy and a dilated fundus exam. The detailed sensorimotor exam will include strabismus measurements, stereoacuity testing, extraocular motility evaluation and photographic documentation. An abbreviated examination will be completed by an orthoptist for the relatives of the subject. This examination will include evaluation of best-corrected visual acuity, external examination, pupils, sensorimotor evaluation, manifest refraction with an autorefractor and undilated ophthalmoscopy.
Each participant will provide: