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Chen Lab | Recent Publications

1.  Liu CH, Sun Y, Li J, Gong Y, Tian KT, Evans LP, Morss PC, Fredrick TW, Saba NJ, Chen J. Endothelial microRNA-150 is an intrinsic suppressor of pathologic ocular neovascularization. Proc Natl Acad Sci U S A. 2015 published ahead of print September 15, 2015. 

2. Sun Y, Liu CH, SanGiovanni JP, Evans LP, Tian KT, Zhang B, Stahl A, Pu WT, Kamenecka TM, Solt LA, Chen J. Nuclear receptor RORα regulates pathologic retinal angiogenesis by modulating Socs3 dependent inflammation. Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10401-6 

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3. Li J, Liu C, Sun Y, Gong Y, Fu Z, Evans LP, Tian KT, Juan AM, Hurst CG, Mammoto A, Chen J.  Endothelial TWIST1 promotes pathological ocular angiogenesis. Invest Ophthalmol Vis Sci. 2014 Nov 20;55(12):8267-77. 
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4. Chen J, Michan S, Juan AM, Hurst CG, Hatton CJ, Pei DT, Joyal J, Evans LP, Cui Z, Stahl A, Sapieha P, Sinclair DA, Smith LE. Neuronal sirtuin1 mediates retinal vascular regeneration in oxygen-induced ischemic retinopathy. Angiogenesis. 2013 Oct;16(4):985-92. PMID: 23912262. (cover article) 
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5. Chen J, Stahl A, Krah NM, Seaward MR, Dennison RJ, Sapieha P, Hua J, Hatton CJ, Juan AM, Aderman CM, Willett KL, Guerin KI, Mammoto A, Campbell M, Smith LE. Wnt signaling mediates pathologic vascular growth in proliferative retinopathy. Circulation. 2011 Oct 25;124(17):1871-81. PMID: 21969016.
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6. Chen J, Connor KM, Aderman CM, Willett KL, Aspegren OP, Smith LE. Suppression of retinal neovascularization by erythropoietin siRNA in a mouse model of proliferative retinopathy. Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1329-35. PMID: 18952918. (cover article)
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7. Chen J, Connor KM, Aderman CM, Smith LE. Erythropoietin deficiency decreases vascular stability in mice. J Clin Invest. 2008 Feb 1;118(2):526-533.  PMID: 18219289. (cover article).
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8. Chen J, Smith LE. Retinopathy of prematurity. Angiogenesis. 2007 Jun;10(2):133-140.
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