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Biobehavioral Pediatric Pain Lab | Brain fMRI in Youth with CRPS

From Simons et al., 2014 PAIN

Led by the Pain Analgesia Imaging Neuroscience (P.A.I.N.) Research Group directed by David Borsook and Lino Becerra, this study utilizes functional magnetic resonance imaging (fMRI) to define the neural circuitry of Complex Regional Pain Syndrome (CRPS) in children and adolescents.

The goal is to better understand the evolution of the brain’s role in the perception of pain in CRPS from the disease state through recovery in order to inform treatment of the condition. Dr. Simons is interested in the neural aspects of pain-related fear and emotional regulation as it relates to the pain experience.

Current status: Enrollment is active. Publications are in print and in progress.

Funding source: K23 NICHD/NIH (LS); R01 NINDS (Borsook); Sara Page Mayo Endowment for Pediatric Pain Research

If you are interested in learning more or participating in the study, please contact us at

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