Research

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Immunology Research

The Division of Immunology has a long track record of cutting edge research in allergic and immunological mechanisms and is recognized world-wide for work on IgE regulation, Current areas of basic research include:

  • Pathogenesis of atopic dermatitis
  • Wiskott Aldrich Syndrome protein (WASP) and associated molecules
  • Signal transduction by the T cell receptor, the role of SLP-76
  • Regulation of IgE production
  • Roles of IgE in allergic pathogenesis and parasite immunity
  • TRAF functions in TNF receptor family signaling

 

Ongoing clinical projects include:

  • The evaluation of immunomodulators in asthma and atopic dermatitis.
  • A study of the efficacy of purified C1 esterase inhibitor in hereditary angioneurotic edema.
  • The evaluation of intravenous gammaglobulin treatment of patients with antibody deficiency disorders.
  • Studies of the use of anti_IgE in the treatment of asthma and atopic dermatitis.

 

Featured researchers in the Division of Immunology hold faculty appointments at Harvard Medical School.

Latest Research in Immunology:

RESEARCHER FOCUS AREA
Raif Geha, MD Immune deficiencies
Luigi Daniele Notarangelo, MD Cellular bases of congenital immunodeficiencies
Hans Oettgen, MD, PhD Allergy
Narayanaswamy Ramesh, PhD Molecular basis of primary immunodeficiencies
Lynda Schneider, MD Allergy
Dale T. Umetsu, MD, PhD The immunobiology of asthma and allergy
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