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In the News

Announcing Partnership with Shire

We are proud to announce a new collaboration program between Shire and Boston Children’s, which will provide funding and additional resources to support development of therapeutics for rare diseases.  This collaboration will hopefully lead to new insights and advances for the indiviudals with orphan disease we serve. 

Investigators who are interested in submitting a project can complete the 2 page preproposal application due January 21st.  Questions about submissions can be directed to Nurjana Bachman in TIDO. 

CLARITY Challenge

The Manton Center partnered with other Children's Hospital Investigators to form the CLARITY Challenge (Children’s Leadership Award for the Reliable Interpretation and appropriate Transmission of Your genomic information).   The goal of the challenge was to identify best methods and practices for improving the reliability and accuracy of the genomics-to-clinic pipeline – spanning sequencing, analysis, interpretation and reporting – to provide the most meaningful results to patients and their families.

The CLARITY Challenge invited researchers from around the world to analyze the whole genome sequences of three families who are suspected to have a genetic basis for their conditions. 

The challenge is now complete and winners were announced! Check out the CLARITY Challenge for more information about the challenge and it's outcomes.

Read even more about the CLARITY Challenge's outcomes in the coverage by Vector in the artivce Using DNA Sequencing in Medicine: The World Starts to Figure Out How


Announcing Sequencing Pilot

This week, Boston's Children's Hospital announced the launch of the new sequencing pilot project for clinical or research use.  This initiative will allow for Children's Investigators with approved IRB protocols to submit samples for whole genome sequencing or exome sequencing.  Please see the application for more details.  Contact Catherine Brownstein with questions.

Wall Street Journal Features Gene Partnership
The Wall Street Journal featured the Gene Partnership (GP), the infrastructure of the Gene Discovery Core (GDC), in a lengthy and in-depth article that highlighted the innovative nature of the program. The project is led by GDC scientists Ingrid Holm, MD, MPH, Isaac Kohane, MD, PhD, Lou Kunkel, PhD, and Kenneth Mandl, MD, MPH, and showcases our commitment to advancing research and medicine.
June, 2010

First Human Embryonic Stem Cell Lines Approved
The NIH press release about the 13 new lines of human embyonic stem cells which have been approved for use in NIH-funded research. Eleven of the 13 cell lines were created in the Daley laboratory.
December 2, 2009

When Milk Threatens Babies
The Boston Globe discusses the relevance of orphan disease research by highlighting Dr. Gerard T. Berry's research and the comprehensive galactosemia conference co-sponsored by The Manton Center in August, 2009.

Rules Will Allow Financing for Old Stem Cell Lines
Dr. George Daley talks about the significance of older stem cell lines being eligible for federally financed research under the Obama administration in The New York Times
July 6, 2009

Louis Kunkel, PhD, chief of the Division of Genetics and a Howard Hughes Medical Investigator, was recently awarded the $250,000 March of Dimes Prize in Developmental Biology. Lou identified the gene and protein dystrophin, which is mutated in boys with Duchenne/Becker muscular dystrophy. The award has been awarded annually since 1996 to investigators whose research has profoundly advanced the science that underlies the understanding of birth defects.

George Daley, MD, PhD, associate chief and director of Pediatric Stem Cell Transplantation, was recently awarded the E. Mead Johnson Award from the American Pediatric Society and Society for Pediatric Research. The award, given since 1939, honors clinical and laboratory research achievements in pediatrics and is considered the most prestigious award in pediatric research.

No Small Change for the Health Information Economy
The Wall Street Journal
features The New England Journal of Medicine article written by Dr. Isaac Kohane and Dr. Ken Mandl discussing the Obama administration's plans for electronic healthcare records
March 26, 2009

Back to the Future
Dr. Luigi Notarangelo and Dr. George Daley are featured in a Vector Online article discussing the clinical and research applications of stem cells

Searching for Strength: One gene at a time
Vector Online describes Dr. Alan Beggs' work on congenital myopathies

Genetics for the people
Dr. Ingrid Holm discusses the future of gene discovery and Boston Children's Hospital's unique role in applying new research to patient care

Making genetics count
Dr. Louis Kunkel is featured in the Vector article discussing The Manton Center's role in gene discovery

Vector Online interviews Dr. George Daley
A video interview of Dr. George Daley discussing the reversal of federal funding restrictions on human embryonic stem cell research

Doctors Raise Doubts on Digital Health Data
The New York Times interviews Dr. Kenneth Mandl and Dr. Isaac Kohane about how economic stimulus money can be used to support health IT
March 25, 2009

Rethink Stem Cells? Science Already Has
Dr. George Daley was quoted by the New York Times about President Obama's action on stem cells
March 9, 2009

Research Named Number 1 of 2008
Research by Dr. George Daley was included among The Boston Globe's "Best of 2008" breakthroughs
December 29, 2008

Andy's Story
NECN talks with patient Andy Trevino's parents and Dr. Alan Beggs about orphan disease research
December 2, 2008

Announcing The Manton Center for Orphan Disease Research
Boston Children's Hospital Press Release
November 12, 2008

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