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MODELING PAIN IN A DISH

Nociceptors made from skin recreate pain physiology
Chronic pain, affecting tens of millions of Americans alone, is debilitating and demoralizing. It has many causes, and in the worst cases, people become "hypersensitized" - their nervous systems fire off pain signals in response to very minor triggers... [ More ]
THE 98% 
Proteomics reveals proteins made from "noncoding" DNA
Vast chunks of our DNA - fully 98 percent of our genome - are considered "non-coding," meaning that they're not thought to carry instructions to make proteins. Yet we aready know this "junk DNA" isn't completely filler... [ More ]
BREAKING INTO THE AUTISTIC BRAIN 

A prismatic research approach sheds light on the biology of autism spectrum disorders
In one laboratory, nerve cells in a plastic dish glow green and red under a microscope, revealing their shapes and the locations of specific molecules. In another laboratory, mice that have grown up in the dark... [click to read more]

FLYING IN THE FACE OF PAIN

Fruit flies aid in the hunt for human pain genes
Ever wonder why some people are less sensitive to pain than others? It's not simply that they're brave, and the rest of us are wimps... [click to read more]

CAN DRUGS IMPROVE COGNITIVE OUTCOMES?

Clinical trials for genetic disorders linked to autism take aim at symptoms previously considered irreversible
Six-year-old Ryan is an expert chef. He especially likes cooking turkey in the toy microwave in the playroom of Children's Hospital Boston's Clinical and Translational Study Unit... [click to read more]

PROTEINS THAT RISE AND FALL TOGETHER

Proteomics and bioinformatics help identify elusive drug targets
Too much junk building up in your Inbox? Just like you might go through your thousands of messages and flag the ones to delete, your cells have a system for sorting through their thousands of proteins and marking the ones to trash... [click to read more]

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